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Online reference database of European Y-chromosomal short tandem repeat (STR) haplotypes.

Abstract：

:The reference database of highly informative Y-chromosomal short tandem repeat (STR) haplotypes (YHRD), available online at http://ystr.charite.de, represents the largest collection of male-specific genetic profiles currently available for European populations. By September 2000, YHRD contained 4688 9-locus (so-called "minimal") haplotypes, 40% of which have been extended further to include two additional loci. Establishment of YHRD has been facilitated by the joint efforts of 31 forensic and anthropological institutions. All contributing laboratories have agreed to standardize their Y-STR haplotyping protocols and to participate in a quality assurance exercise prior to the inclusion of any data. In view of its collaborative character, and in order to put YHRD to its intended use, viz. the support of forensic caseworkers in their routine decision-making process, the database has been made publicly available via the Internet in February 2000. Online searches for complete or partial Y-STR haplotypes from evidentiary or non-probative material can be performed on a non-commercial basis, and yield observed haplotype counts as well as extrapolated population frequency estimates. In addition, the YHRD website provides information about the quality control test, genotyping protocols, haplotype formats and informativity, population genetic analysis, literature references, and a list of contact addresses of the contributing laboratories.

journal_name

Forensic Sci Int

journal_title

Forensic science international

authors

Roewer L,Krawczak M,Willuweit S,Nagy M,Alves C,Amorim A,Anslinger K,Augustin C,Betz A,Bosch E,Cagliá A,Carracedo A,Corach D,Dekairelle AF,Dobosz T,Dupuy BM,Füredi S,Gehrig C,Gusmaõ L,Henke J,Henke L,Hidding M,

doi

10.1016/s0379-0738(00)00478-3

keywords:

subject

Has Abstract

pub_date

2001-05-15 00:00:00

pages

106-13

issue

2-3

eissn

0379-0738

issn

1872-6283

pii

S0379073800004783

journal_volume

118

pub_type

杂志文章

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