Abstract：
:An extraction and determination method of most important amphetamine derivatives in serum has been developed. The procedure comprises liquid-liquid extraction with tert-butyl methyl ether of the sample under basic conditions, centrifugation, formation of hydrochloric salts after the separation of organic phase, vacuum evaporation of the organic solvent at 60 degrees C, and trifluoroacetylation by on-line flash injection with MBTFA. GC analysis was performed by electron impact GC-MS in SIM mode. In this way satisfactory identification of 12 amphetamine derivatives could be obtained. Amphetamine, methamphetamine, MDA, MDMA and MDEA could be analyzed by using pentadeuterated analogs as internal standards. Low limits of detection 2.5-6.9 ng/mL could be reached. The assay was linear within the 5-100 ng/mL range with a regression coefficient greater than 0.999 for each compound. Our derivatization method is of low cost since only 1 microL of MBTFA is used for each flash trifluoroacetylation.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Hidvégi E,Fábián P,Hideg Z,Somogyi Gdoi
10.1016/j.forsciint.2006.03.030subject
Has Abstractpub_date
2006-09-12 00:00:00pages
119-23issue
2-3eissn
0379-0738issn
1872-6283pii
S0379-0738(06)00348-3journal_volume
161pub_type
杂志文章abstract：BACKGROUND:The study of post mortem vitreous magnesium (Mg) is less common than sodium (Na), chloride (Cl) and potassium (K) in the forensic literature. There is no accepted normal range for post mortem vitreous Mg and the relationship between post mortem vitreous Mg levels and post mortem interval (PMI), other electro...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.12.038
更新日期：2018-03-01 00:00:00
abstract：:Forensic science faces many challenges, some high profile and others that are less visible. It is argued that a holistic understanding of the complex matrix of forensic science is critical to robust and transparent forensic reconstruction approaches. This paper explores the value of incorporating the contrasting appro...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.08.026
更新日期：2018-11-01 00:00:00
abstract：:In 1968, when the Harvard Committee defined brain-death to characterize irreversible coma, the question of when a doctor might stop resuscitation remained unresolved: brain-death is a safe, but not a sufficient criterion. Furthermore, the committee defined brain-death to be the death of man without any more than pragm...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(94)90388-3
更新日期：1994-12-16 00:00:00
abstract：:Conservation of the three-dimensional aspect of bitemarks optimizes their analysis. Although bitemarks could be recorded with a surface scanner, in clinical dentistry, intraoral scanners are used as an alternative to conventional dental impressions. Here we assess the reproducibility and the reliability of a three-dim...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110198
更新日期：2020-04-01 00:00:00
abstract：INTRODUCTION:3-methoxyphencyclidine (3-MeO-PCP) appeared on the illicit drug market in 2011 and is an analogue of phencyclidine, which exhibits anesthetic, analgesic and hallucinogenic properties. In this paper, we report data from a non-fatal intoxication and seven deaths involving 3-MeO-PCP in Sweden during the perio...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.02.034
更新日期：2017-06-01 00:00:00
abstract：:We developed a q-PCR technique that simultaneously evaluates the extent of degradation and determines the gender of a human DNA donor. QYDEG HRM is a triplex real-time PCR whose products are analysed by high-resolution melting (HRM). The system produces three amplicons: (1) transducin (beta)-like 1, Y-linked (TBL1Y) (...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.11.013
更新日期：2019-02-01 00:00:00
abstract：:The procedure used in this laboratory for removing and identifying contamination of hair specimens with drugs is demonstrated by its application to hair contaminated by various experimental models. The models include soaking; coating with drug followed by sweat conditions for 6 h; and soaking in a very high concentrat...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.04.024
更新日期：2004-10-29 00:00:00
abstract：:The Bayesian approach provides a unified and logical framework for the analysis of evidence and to provide results in the form of likelihood ratios (LR) from the forensic laboratory to court. In this contribution we want to clarify how the biometric scientist or laboratory can adapt their conventional biometric system...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.11.007
更新日期：2005-12-20 00:00:00
abstract：:We describe two suicide cases in which old paraquat was ingested. In conjunction with lung involvement a pronounced degeneration was observed in skeletal muscle of one who died on the 14th day after the ingestion. The following sarcoplasmic or endoplasmic reticulum Ca2+ ATPase (SERCA) monoclonal antibodies were used f...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(98)00190-x
更新日期：1999-03-15 00:00:00
abstract：:The detection of buried firearms remains a critical issue in law enforcement. We assess the suitability of magnetic gradiometers to detect buried rifles and handguns at multiple depths using numerical modeling and field investigations. Our simulation is based on a simple approach to characterize handguns and rifles as...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110396
更新日期：2020-09-01 00:00:00
abstract：INTRODUCTION:The intoxicated person may cause harm to others, often requiring expert evaluation for the determination of guilt. The primary aim of this study was to determine the mechanisms of mistakes that led 17 doctors accused of working under the influence of alcohol to face malpractice. We also wanted to clarify w...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2018.01.019
更新日期：2018-04-01 00:00:00
abstract：:False positives due to the presence of antimony in vehicle seat fabrics are a problem in gunshot residue (GSR) analysis, in particular, when graphite furnace atomic absorption spectrometry (GFAAS) is employed. In this study, we sought to determine the reason for the prevalence of false positive results and to propose ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.03.006
更新日期：2015-05-01 00:00:00
abstract：:One hundred and ten pairs of blood and semen samples and their stains were studied to type glyoxalase 1 (GLO 1) isoenzymes using agarose-starch medium. A good agreement was observed between the phenotypes expressed in blood and semen samples of the same donor. No GLO 1 activity however could be demonstrated in the vag...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90185-5
更新日期：1988-05-01 00:00:00
abstract：:Reports in the literature suggest that diagnostic differences in craniofacial morphology between blacks and whites arise very early in development. These reports, however, have not been consistent regarding which traits are diagnostic and have failed to provide forensic anthropologists with a reliable method of assess...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.02.009
更新日期：2005-07-16 00:00:00
abstract：:The cyanide distribution in five fatal cyanide poisonings was analyzed by the pyridine-pyrazolone method using a Conway diffusion cell. In order to study the effect of storage conditions on cyanide concentration in tissue samples, the cyanide concentrations were first measured immediately after collection of the sampl...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(88)90164-8
更新日期：1988-09-01 00:00:00
abstract：:The reference database of highly informative Y-chromosomal short tandem repeat (STR) haplotypes (YHRD), available online at http://ystr.charite.de, represents the largest collection of male-specific genetic profiles currently available for European populations. By September 2000, YHRD contained 4688 9-locus (so-called...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00478-3
更新日期：2001-05-15 00:00:00
abstract：:A new discrimination method for the bioapatite materials bone, antler and ivory was developed using X-ray diffractometry and comprises non-invasive measurements in order to take valuable objects into account. Our approach deals with the analysis of peak intensity ratios resulting from several measurements on each obje...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2020.110159
更新日期：2020-03-01 00:00:00
abstract：:We describe two cases of human consumption of seeds from Argyreia nervosa (Hawaiian Baby Woodrose), which resulted in one fatality due to falling from a building and one surviving witness. The principal psychoactive constituent of the seeds, lysergamide (LSA), was recovered from blood and urine samples by mixed-mode c...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.11.017
更新日期：2010-04-15 00:00:00
abstract：:Forensic pathologists are often involved in the identification of unknown bodies. It is imperative, therefore, that they become aware of a national computerized identification system (NCIC) administered by the FBI. There is also a state system in California which has resulted in the identification of 59 individuals. T...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(86)90013-7
更新日期：1986-02-01 00:00:00
abstract：:Suicide has been reported as the second or third most common cause of death in children and adolescents worldwide. In this study, cases of under the age of 19 years submitted to the Institute of Forensic Medicine, First Specialization Board between 1996 and 2000 as suicides by the Board were evaluated retrospectively....
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2003.11.024
更新日期：2004-05-28 00:00:00
abstract：:In an investigation of postmortem ethanol diffusion deuterium-labeled ethanol-d6 was instilled by peroral gavage immediately after death by CO into the stomach of rat carcasses which were subsequently kept for 12-72 h at 5 or 30 degrees C. The heart blood, abdominal fluid and several tissues were collected and analyze...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(95)01820-4
更新日期：1995-12-29 00:00:00
abstract：:We have performed a population genetic study on a population from South Saxony-Anhalt, Germany. The allele distributions of the systems DYS19, DYS385, DYS389I/II DYS390, DYS391, DYS392 and DYS393 were investigated in a sample of 234 unrelated males. PCR products were detected using capillary electrophoresis on the ABI...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.01.004
更新日期：2005-12-20 00:00:00
abstract：:An increased number of police enquiries involving human remains buried with lime have demonstrated the need for more research into the effect of different types of lime on cadaver decomposition and its micro-environment. This study follows previous studies by the authors who have investigated the effects of lime on th...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2013.12.046
更新日期：2014-05-01 00:00:00
abstract：UNLABELLED:The paper gives a review of the development of methods of postmortem electrical excitability of skeletal muscle for determining the time since death. For practical application in casework, the following method can be proposed: position of electrodes in the orbicularis oculi muscle, stimulation by rectangular...
journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/0379-0738(90)90291-6
更新日期：1990-10-01 00:00:00
abstract：:Formalin-fixed and paraffin-embedded tissue (FF-PET) is an invaluable resource for retrospective molecular genetic studies, but the extraction of high-quality genomic DNA from FF-PET is still a problematic issue. Despite the range of DNA extraction methods currently in use, the association of phenol-chloroform extract...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.09.004
更新日期：2010-01-30 00:00:00
abstract：:Short tandem repeats (STRs) or microsatellites have been recognized worldwide as a powerful tool for human identification. They have become widely used in human identification especially in criminal cases and mass disasters. Police departments are often interested in cases where tissues are already decomposed and only...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.09.052
更新日期：2004-12-02 00:00:00
abstract：:Most of the automotive companies use cast iron for their engine blocks. Restoration of obliterated number on these iron surfaces by chemical etching is known to be quite difficult. Heating of the obliterated surface using oxyacetylene flame is an alternative recovery treatment suggested in literature and used in pract...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.07.020
更新日期：2012-11-30 00:00:00
abstract：:The mass spectrum of the drug of abuse 2,5-dimethoxyamphetamine (2,5-DMA) is characterized by an imine fragment base peak at m/z 44 and additional fragments at m/z 151/152 for the dimethoxybenzyl cation and radical cation, respectively. Five positional ring isomers of dimethoxyamphetamines (DMA) have an isomeric relat...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.08.010
更新日期：2009-11-20 00:00:00
abstract：:Diphenhydramine is one of the first effective antihistamine agents to have been discovered. The compound is also used for its sedative and antiemetic effects. The first case involving repetitive sedation linked to the use of diphenhydramine as a drug-facilitated crime and subsequent impairment of a 9-year-old female v...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.12.006
更新日期：2007-12-20 00:00:00
abstract：:In prosecution, Belgian judiciary currently uses outdated yield figures (28.1g per plant, sold at € 3/g at grower level) for fining illicit indoor cannabis plantations. Using state-of-the-art cultivation techniques, our growth experiments showed that yield is better expressed in g/m(2) cultivated surface area rather t...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2012.03.013
更新日期：2012-07-10 00:00:00
