Abstract:
:Topical and intralesional corticosteroids (CS) are effective treatments for oral manifestations of autoimmune vesiculobullous diseases (VBD); however, may cause unnecessary absorption in the adjacent healthy mucosal surfaces, local infections, atrophy, and injection pain. To propose a protocol using a unique modality for targeted administration of CS for the treatment of local manifestations of oral VBD. The medical records of nine patients with systemic CS-resistant VBD oral lesions, were reviewed following 3 weeks of treatment and 3 months of tapering using a custom-made tray designed for precise application of topical CS targeted to the involved mucosa. Following treatment, lesions have healed in 8/9 patients. Involvement of surrounding mucosa was minimal, and no systemic adverse effects were recorded. The proposed protocol using custom-made trays for targeted CS treatment could be an effective alternative treatment for oral VBD.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Porat Ben Amy D,Kassem Rdoi
10.1111/dth.14446subject
Has Abstractpub_date
2020-11-01 00:00:00pages
e14446issue
6eissn
1396-0296issn
1529-8019journal_volume
33pub_type
杂志文章abstract::There are many developmental abnormalities that may appear in the neonate and in infants when critical steps in embryogenesis fail. These steps are often not fatal but can lead to significant morbidity for those patients affected. A logical approach is needed in addressing both the diagnostic and therapeutic issues th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2005.05016.x
更新日期:2005-03-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00229.x
更新日期:2008-10-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12465
更新日期:2017-05-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13101
更新日期:2019-11-01 00:00:00
abstract:INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14254
更新日期:2020-11-01 00:00:00
abstract::Maintaining the health of dermal fibroblast cells and controlling their growth and proliferation would directly affect the health of skin tissues. The present study encompassed three control and three experimental specimens, which were different in terms of the duration of exposure to electromagnetic field (EMF) and i...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13803
更新日期:2020-07-01 00:00:00
abstract::Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe chronic hand eczema in terms of drug survival and reasons for discontinuation. Patients ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12362
更新日期:2016-09-01 00:00:00
abstract::Photodynamic therapy (PDT) is an established nonsurgical treatment for nodular basal cell carcinoma (nBCC). This study compares the clinical, histopathological, and immunohistochemical findings in recurrent nBCC after PDT versus pre-treatment (primary) nBCC. This retrospective study analyzed nodular BCCs treated with ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14779
更新日期:2021-01-13 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2006.00080.x
更新日期:2006-07-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00196.x
更新日期:2008-07-01 00:00:00
abstract::The purpose of the work was to assess changes in chemerin and irisin levels in women with diagnosed intrahepatic cholestasis of pregnant women treated with ursodeoxycholic acid. The study group consisted of 50 patients with diagnosed and confirmed intrahepatic cholestasis of pregnant women at 24-25 weeks of pregnancy ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13272
更新日期:2020-03-01 00:00:00
abstract::Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin and mucous membrane injury, which may cause acute and chronic dermatitis, secondary infection and aggravation of underlying skin diseases. This is a consensus of Chinese experts on protective measures and advice on hand-cleaning- ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13310
更新日期:2020-07-01 00:00:00
abstract::Nail involvement can place a significant burden on patients as a result of functional damage and psychosocial problems, leading to major repercussions on the quality of life. There is strong evidence that nail psoriasis can often be difficult to treat. We report a 69-year-old man with severe onychodystrophy, onycholys...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12914
更新日期:2019-05-01 00:00:00
abstract::Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse cutaneous drug reaction with mortality up to 10%. It is a rare condition with risk varying between 1 in 1000 and 1 in 10 000 drug exposures. The aim of the study was to describe clinical features, management and drugs responsible for cau...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14670
更新日期:2020-12-14 00:00:00
abstract::A previous study has defined the maculopapular subtype of manifestations of COVID-19. The objective of our study was to describe and classify maculopapular eruptions associated with COVI-19. We carried out a subanalysis of the maculopapular cases found in the previous cross-sectional study. Using a consensus, we defin...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14170
更新日期:2020-11-01 00:00:00
abstract::This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2008.00202.x
更新日期:2008-07-01 00:00:00
abstract::This is the first report of a case of porocarcinoma that was successfully treated with maxacalcitol and imiquimod. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.12830
更新日期:2019-03-01 00:00:00
abstract::Epidermolysis Bullosa (EB) is a rare group of diseases caused by genetic variants in skin structural proteins. EB is characterized by varying degrees of skin fragility, blisters and impaired wound healing, and is classified based on the ultrastructural levels of skin cleavage-simplex, junctional, dystrophic, and Kindl...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14093
更新日期:2020-11-01 00:00:00
abstract::Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12504
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:There are conflicting results in the literature regarding the frequency of allergic diseases in COVID-19 patients. The effect of having an allergic disease on COVID-19 disease severity has been little studied. In this study, we tried to determine the frequency of allergic diseases in COVID-19 patients and th...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14581
更新日期:2020-11-25 00:00:00
abstract::Genital ulcer disease (GUD) constitutes a major public health problem. Most of them are the result of sexually transmitted diseases. Genital herpes, syphilis, lymphogranuloma venereum, granuloma venereum, or chancroid are the commonly encountered GUD. The treatment modalities for these disorders have changed with adve...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2008.00191.x
更新日期:2008-05-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2007.00149.x
更新日期:2007-09-01 00:00:00
abstract::Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12309
更新日期:2016-03-01 00:00:00
abstract::A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12724
更新日期:2018-11-01 00:00:00
abstract::Emollients are acknowledged as a part of standard care in therapeutic and prevention protocols as well as a part of everyday skin care routine. When it comes to making a final decision between two emollient products, the ingredient list, that is, the formulation composition could be the determining factor. In such cas...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14020
更新日期:2020-11-01 00:00:00
abstract::Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Bloc...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12899
更新日期:2019-05-01 00:00:00
abstract::Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13022
更新日期:2019-09-01 00:00:00
abstract::Immunosuppressive and immunomodulatory therapies are important in dermatology, but indications are influenced by SARS-CoV-2. We will focus on skin disorders such as autoimmune connective tissue disorders, neutrophilic dermatoses, and vasculitis. Immunomodulators such as colchicine and antimalarials can easily be prefe...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13686
更新日期:2020-09-01 00:00:00
abstract::Ultrapotent topical corticosteroids and circumcision are usually effective for male genital lichen sclerosus (MGLSc); however, refractory cases are often referred to our Male Genital Dermatology Unit. Treatment with autologous platelet-rich plasma (TPRP) has recently been advocated as a safe and effective treatment op...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14032
更新日期:2020-11-01 00:00:00
abstract::Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma. This condition is difficult to diagnose because of its large size and expansive nature and may be diagnosed as a malignant tumor. There are various treatments such as surgery and oral retinoids; however, limited studies have verified th...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13291
更新日期:2020-05-01 00:00:00