Biologic therapy for acrodermatitis continua of Hallopeau: Successful treatment with secukinumab and review of the literature.

Abstract:

:Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Blockade of the IL-17 receptor A has shown promise in the treatment of psoriatic erythroderma and generalized pustular psoriasis not responsive to conventional treatment. A rapid response was observed in our patient, in both skin lesions and arthritic symptoms, underlining the ability of secukinumab to improve symptoms beyond those of plaque psoriasis.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Galluzzo M,D'Adamio S,Teoli M,Bianchi L,Talamonti M

doi

10.1111/dth.12899

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

e12899

issue

3

eissn

1396-0296

issn

1529-8019

journal_volume

32

pub_type

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