Abstract:
:Cumulative exposure to ultraviolet radiation (UVR) increases the risk of developing skin cancer, particularly squamous cell carcinoma and basal cell carcinoma. Thus, the need for protection from the sun is widely advocated, but consumers generally associate such protection with the occasional extreme exposure and tend to ignore the risk of long-term exposure. In fact, a sun exposure model predicts that over a lifetime, a person will receive tens of thousands of minimal erythema doses worth of UVR through normal, daily, incidental exposure. The cumulative effect of casual sun exposure over the years underscores the need for everyday basic UVR protection in which even low level (SPF 4-10) sunscreens are shown to offer significant benefit. Analysis shows that daily protection can reduce lifetime exposure by 50% or more.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Nole G,Johnson AWdoi
10.1111/j.1396-0296.2004.04s1007.xkeywords:
subject
Has Abstractpub_date
2004-01-01 00:00:00pages
57-62eissn
1396-0296issn
1529-8019pii
04S1007journal_volume
17 Suppl 1pub_type
杂志文章,评审abstract::Isotretinoin is a safe and useful medication for acne management. Adverse effects are mostly related to cutaneous and mucous membranes. We present a case of a 24-year-old female patient who was on treatment with isotretinoin for acne vulgaris Grade 4. After 6 months of treatment, the patient presented with localized p...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13280
更新日期:2020-05-01 00:00:00
abstract::Androgenetic alopecia also known as pattern alopecia, is a disorder characterized by the gradual onset of the conversion of terminal hairs into vellus hairs. Dexpanthenol has an anti-oxidative and anti-inflammatory effect and a cellular repair capability. We present nine male cases who had marked improvement after rec...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13381
更新日期:2020-05-01 00:00:00
abstract::Acne cysts are a common dermatological problem that often leads to scarring and a significant negative impact on patients' psyche. The aim of the study was to evaluate the usefulness of intralesional foam sclerotherapy for the treatment of cystic acne. Patients with cystic acne treated with intralesional foam scleroth...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13505
更新日期:2020-11-01 00:00:00
abstract::Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13022
更新日期:2019-09-01 00:00:00
abstract::Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01318.x
更新日期:2010-05-01 00:00:00
abstract::Nucleosomes are typically located intracellularly, and extracellular levels of nucleosomes indicated the degree of cell death. We postulated aberrant nucleosomes expression in dermatomyositis (DM) and polymyositis (PM). To assess the aberrant expression of circulating nucleosomes in DM and polymyositis. 76 consecutive...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14460
更新日期:2020-11-01 00:00:00
abstract::Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12503
更新日期:2017-09-01 00:00:00
abstract::It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages o...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2012.01533.x
更新日期:2012-01-01 00:00:00
abstract::Pustulosis palmoplantaris (PPP; synonyms: pustulosis palmaris et plantaris, palmoplantar amicrobic pustulosis) is a common chronic, relapsing, pustular eruption affecting the palms and soles. The authors report the successful treatment of six therapy-experienced patients with histologically confirmed PPP with oral itr...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2008.01219.x
更新日期:2009-01-01 00:00:00
abstract::Dialkylcarbamoylchloride (DACC)-coated cotton acetate dressing works directly through hydrophobic interaction to reduce the number of bacteria without the risk of resistance. It is easy to use and therefore expected to improve patient's compliance. This study aimed to assess the clinical efficacy of DACC-coated cotton...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13047
更新日期:2019-09-01 00:00:00
abstract::Topical application of timolol cream is effective and convenient for treating superficial infantile hemangiomas. Intralesional injection of corticosteroids, such as diprospan, is useful for the treatment of superficia infantile hemangiomas without systemic side effects. We conducted a self-controlled study to investig...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12595
更新日期:2018-05-01 00:00:00
abstract::Bexarotene is a retinoid that specifically binds retinoid X receptors and has numerous effects on cellular growth and differentiation. It is approved for the treatment of cutaneous T cell lymphoma both topically and systemically. Adverse effects include hyperlipidemia, central hypothyroidism, and neutropenia with bexa...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12087
更新日期:2013-09-01 00:00:00
abstract::Although there is still some controversy about the existence of psoriatic arthritis as a specific form of inflammatory arthritis associated with psoriasis, epidemiological, and clinical studies support the unique features of psoriatic arthritis. Because of lack of diagnostic or classification criteria, the disease has...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2004.04038.x
更新日期:2004-01-01 00:00:00
abstract::Generalized eruptive keratoacanthoma, is considered a serious condition because the eruptions are diffuse, persistent, and recurrent. Constant pruritus, visceral neoplasms, and unsatisfactory response to treatment are ominous prognostic factors. Even if skin cancers are usually well controlled with surgical and/or rad...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12374
更新日期:2016-09-01 00:00:00
abstract::Physicians and patients have come to expect that our prescription topicals not only be efficacious but also minimally irritating and cosmetically pleasing. Much research and development effort are being spent to identify new vehicles to achieve these goals. Consumers are also demanding nonprescription products that gi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2012.01501.x
更新日期:2012-05-01 00:00:00
abstract::Acute urticaria is a self-limited cutaneous condition marked by transient, erythematous, and pruritic wheals. It is a hypersensitivity response that is often secondary to infection, medications, or food allergies in children. In contrast, the urticarial "mimickers" described in this review article are often seen in th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12103
更新日期:2013-11-01 00:00:00
abstract::Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse cutaneous drug reaction with mortality up to 10%. It is a rare condition with risk varying between 1 in 1000 and 1 in 10 000 drug exposures. The aim of the study was to describe clinical features, management and drugs responsible for cau...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14670
更新日期:2020-12-14 00:00:00
abstract::Some studies have demonstrated that neurotransmitters are involved in the pathogenesis of numerous skin conditions, including psoriasis, addressing the close correlation between the skin and the central nervous system. There are reports showing psoriasis improvement after peripheral nervous system injury. In addition,...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14319
更新日期:2020-11-01 00:00:00
abstract::Keratitis-ichthyosis-deafness (KID syndrome) is a syndromes ichthyoses that is clinically and genetically heterogeneous requiring early and long-term multidisciplinary monitoring of affected individuals. A review of the clinical, etiopathogenic and therapeutic aspects is presented of this rare congenital ectodermal di...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13507
更新日期:2020-07-01 00:00:00
abstract::This article refers to papulosquamous diseases that are seen in the elderly. Many of these diseases are complex to diagnose due to the fact that they are difficult to identify, because they may resemble a similar disorder, which can be misleading. The problem that is frequently seen with these diseases is that they ar...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1046/j.1529-8019.2003.01633.x
更新日期:2003-01-01 00:00:00
abstract::To evaluate the preventive practices in family members of melanoma patients regarding melanoma in Turkey and compare our results with similar studies by a literature review. A questionnaire-based, cross-sectional study was conducted in 52 participants over the age of 18 years. The questionnaire consisted of the items ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14268
更新日期:2020-11-01 00:00:00
abstract::Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00164.x
更新日期:2008-01-01 00:00:00
abstract::Alopecia areata (AA) is a common disease that results in nonscarring hair loss. Recently, tofacitinib (TOFA) has been a novel promising therapy for AA. The aim of this study is to determine the efficacy of oral TOFA treatment for alopecia areata (AA), and alopecia universalis (AU). Data of nine patients treated with o...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13118
更新日期:2019-11-01 00:00:00
abstract::Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO(2) laser treatment shows peculiar effects in the skin, mainly due to its ability of modula...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2012.01531.x
更新日期:2012-11-01 00:00:00
abstract::Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14041
更新日期:2020-11-01 00:00:00
abstract::Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Bloc...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12899
更新日期:2019-05-01 00:00:00
abstract::Intralesional methotrexate (il-MTX) has been reported as a useful therapy in keratoacanthoma (KA) and cutaneous squamous cell carcinoma (cSCC). However, the data available on the histological changes induced by this therapy are very scarce. We conducted a single center, prospective study that included 65 cases of cSCC...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14377
更新日期:2020-11-01 00:00:00
abstract::Psoriasis impacts the quality of life (QoL) by disrupting overall health and social life. Thus, the use of a QoL evaluation item is crucial in assessing a therapeutic regimen. Also, faster improvements in QoL lead to better patient compliance, but very few studies compare psoriasis traditional and biologic therapies t...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13021
更新日期:2019-09-01 00:00:00
abstract::Merkel cell carcinoma is rare and aggressive skin cancer, which occurrence is linked to exposure to ultraviolet light and the Merkel-cell polyomavirus. In recent years, significant progress in understanding the mechanism of Merkel cell carcinoma pathogenesis has been observed. This neoplasm often expresses PD-L1, and ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13281
更新日期:2020-05-01 00:00:00
abstract::Clinical research plays a very important role in the development of drugs and devices, including those for wound healing. The process of initiating a clinical trial can be rather daunting, particularly with the ever-increasing regulatory hurdles. Many clinicians are generally either not trained or have limited knowled...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2006.00095.x
更新日期:2006-11-01 00:00:00