Topical and oral bexarotene.

Abstract:

:Bexarotene is a retinoid that specifically binds retinoid X receptors and has numerous effects on cellular growth and differentiation. It is approved for the treatment of cutaneous T cell lymphoma both topically and systemically. Adverse effects include hyperlipidemia, central hypothyroidism, and neutropenia with bexarotene capsules, and an irritant dermatitis with bexarotene gel. With aggressive management of these potential side effects, bexarotene is an additional option in the armamentarium for management of cutaneous T cell lymphoma.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Schadt CR

doi

10.1111/dth.12087

subject

Has Abstract

pub_date

2013-09-01 00:00:00

pages

400-3

issue

5

eissn

1396-0296

issn

1529-8019

journal_volume

26

pub_type

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