Abstract:
:Topical application of timolol cream is effective and convenient for treating superficial infantile hemangiomas. Intralesional injection of corticosteroids, such as diprospan, is useful for the treatment of superficia infantile hemangiomas without systemic side effects. We conducted a self-controlled study to investigate whether a combination of intralesional injection of diprospan with topical timolol 0.5% cream would be more efficient than timolol cream alone in thick superficial infantile hemangiomas. Thirty-eight patients with 39 thick superficial infantile hemangiomas were recruited. Each lesion was randomly divided into two equal parts: one part was treated with topical timolol 0.5% cream (timolol cream group), while the other part was treated with injection of diprospan combined with topical timolol 0.5% cream (combined treatment group). Infants were followed every 4 weeks to determine whether injections should be continued, and timolol cream was applied four times daily for 5 months. During 5 months of treatment, three specialist physicians were invited to evaluate the therapeutic effects. The combined treatment group showed better lesion involution than did the timolol cream group regarding lesion thickness and color of lesions. The combination of intralesional injection of diprospan with topical timolol 0.5% cream is a suitable and safe strategy for thick superficial infantile hemangiomas.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Xu P,Yu Q,Huang H,Zhang W,Li Wdoi
10.1111/dth.12595subject
Has Abstractpub_date
2018-05-01 00:00:00pages
e12595issue
3eissn
1396-0296issn
1529-8019journal_volume
31pub_type
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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更新日期:2020-11-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
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更新日期:2010-01-01 00:00:00
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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pub_type: 杂志文章
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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