Clinical research in dermatology: 10 steps to getting started.

abstract：:Acrodermatitis continua of Hallopeau (ACH) is a chronic, inflammatory, and relapsing disorder characterized by the progressive destruction of fingernails and toenails. This condition is rare, difficult to treat, and often misdiagnosed. Several antipsoriatic treatments have been used, without any therapeutic guideline ...

journal_title：Dermatologic therapy

authors： Lanna C,Cesaroni GM,Mazzilli S,Lozzi F,Palumbo V,Diluvio L,Bianchi L,Campione E

更新日期：2019-07-01 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

journal_title：Dermatologic therapy

authors： Accordino RE,Engler D,Ginsburg IH,Koo J

更新日期：2008-01-01 00:00:00

abstract：:The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...

journal_title：Dermatologic therapy

authors： Passanisi S,Arasi S,Caminiti L,Crisafulli G,Salzano G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：:Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...

journal_title：Dermatologic therapy

authors： Kennemer C,Pavlidakey P,Sami N

更新日期：2017-07-01 00:00:00

abstract：:The present authors report the case of a 9-year-old boy affected by psoriasis, juvenile psoriatic arthritis, enthesitis, and celiac disease. The signs and symptoms of the different comorbidities appeared at different times in the clinical history, complicating the overall diagnostic and therapeutic procedures. Coopera...

journal_title：Dermatologic therapy

authors： Prignano F,Bonciani D,Bandinelli F,Matucci Cerinic M,Lotti T

更新日期：2010-03-01 00:00:00

abstract：:We report a case of Alternaria alternata cutaneous and pulmonary infection in a 62-year-old man after heart transplantation treated by azole antifungals. Alternaria spp. belong to a group of opportunistic dematiaceous fungi with worldwide distribution. The cutaneous form of the infection in human is very rare and occu...

journal_title：Dermatologic therapy

authors： Sečníková Z,Jůzlová K,Vojáčková N,Kazakov DV,Hošková L,Fialová J,Džambová M,Hercogová J

更新日期：2014-05-01 00:00:00

abstract：:Melasma is a hard-to-manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064-nm low-fluence Q-switched...

journal_title：Dermatologic therapy

authors： Abdel Hay R,Mohammed FN,Sayed KS,Abd El Fattah NA,Ibrahim S

更新日期：2020-07-01 00:00:00

abstract：:The rise in popularity and demand for nonsurgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimize the potential for cross-contam...

journal_title：Dermatologic therapy

authors： Murthy R,Eccleston D,Mckeown D,Parikh A,Shotter S

更新日期：2020-10-17 00:00:00

abstract：:Large difficult to heal ulcers of various etiologies carry a high morbidity and mortality rate. Becaplermin is a recombinant platelet-derived growth factor approved for treatment of diabetic ulcers. In this two-case series, we report the use of becaplermin in the treatment of ulcers due to (i) calciphylaxis, an often ...

journal_title：Dermatologic therapy

authors： Twu O,Mednik S,Scumpia P,Doaty S,Worswick S

更新日期：2016-03-01 00:00:00

abstract：:Growth factors play an important role in reversing the effects of skin aging mediated by chronological and environmental factors. Excessive oxidation of intra- and extracellular components result in breakdown of collagen and elastin network in the dermis and produce the effect of facial aging. Topical application of h...

journal_title：Dermatologic therapy

authors： Mehta RC,Fitzpatrick RE

更新日期：2007-09-01 00:00:00

abstract：:Solid organ transplant recipients are at a significantly increased risk of developing skin cancer. Both systemic and topical retinoids are useful for chemosuppression of skin cancer in this patient population. These drugs can reduce both the present extent and the future development of premalignant and malignant skin ...

journal_title：Dermatologic therapy

authors： Neuhaus IM,Tope WD

更新日期：2005-01-01 00:00:00

abstract：:The oral mucosa is a common site for collateral damage of cancer therapies, including radiation, cytotoxic medication, and newer targeted therapies. Ulcerative oral mucositis is typically painful and affects oral functions including speech, and oral intake of food and medications, thus impacting the quality of life. D...

journal_title：Dermatologic therapy

authors： Barasch A,Epstein JB

更新日期：2011-07-01 00:00:00

abstract：:Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been an open debate on the impact of biological drugs used in the treatment of psoriasis. To define whether patients under treatment with biologics suffer from increased morbidity and mortality from COVID-19, compared to psoriatic patients ...

journal_title：Dermatologic therapy

authors： Brazzelli V,Isoletta E,Barak O,Barruscotti S,Vassallo C,Giorgini C,Michelerio A,Tomasini CF,Musella V,Klersy C

更新日期：2020-11-01 00:00:00

abstract：:Nail involvement can place a significant burden on patients as a result of functional damage and psychosocial problems, leading to major repercussions on the quality of life. There is strong evidence that nail psoriasis can often be difficult to treat. We report a 69-year-old man with severe onychodystrophy, onycholys...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Chimenti MS,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of pati...

journal_title：Dermatologic therapy

authors： Del Boz J,Millán-Cayetano JF,García-Montero P,García-Harana C,Rivas-Ruiz F,de Troya-Martín M

更新日期：2018-07-01 00:00:00

abstract：:Verrucas are often recalcitrant to conventional cryotherapy. Since 1970, intralesional bleomycin has been used off-label by dermatologists. But in some cases, the results of intralesional bleomycin were disappointing. Vincristine is a well-known vinca alkaloid antiblastic drug that has been used for treating hematolog...

journal_title：Dermatologic therapy

authors： Lee JR,Youn JH,Roh JY

更新日期：2011-05-01 00:00:00

abstract：:Off-label treatment with reduced doses of biological therapies for moderate-severe psoriasis is used, but its efficacy, safety, and persistence are not well known. We have compared reduced doses with standard an escalated doses and study predictive factors for a successful reduction of doses lasting more than 6 months...

journal_title：Dermatologic therapy

authors： Llamas-Velasco M,Daudén E

更新日期：2020-11-01 00:00:00

abstract：:Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...

journal_title：Dermatologic therapy

authors： Bar-Ilan E,Koren A,Shehadeh W,Mashiah J,Sprecher E,Artzi O

更新日期：2020-01-01 00:00:00

abstract：:Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser...

journal_title：Dermatologic therapy

authors： Mu YZ,Jiang L,Yang H

更新日期：2019-11-01 00:00:00

abstract：:Hand dermatitis is a common skin condition that often has a chronic and/or relapsing clinical course. Several clinical forms of hand dermatitis have been described, including contact (i.e., allergic and irritant), hyperkeratotic (i.e., psoriasiform or tylotic), frictional, nummular, atopic, pompholyx (i.e., dyshidrosi...

journal_title：Dermatologic therapy

authors： Warshaw EM

更新日期：2004-01-01 00:00:00

abstract：:Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...

journal_title：Dermatologic therapy

authors： Agha R,Mirowski GW

更新日期：2010-05-01 00:00:00

abstract：:Topical and intralesional corticosteroids (CS) are effective treatments for oral manifestations of autoimmune vesiculobullous diseases (VBD); however, may cause unnecessary absorption in the adjacent healthy mucosal surfaces, local infections, atrophy, and injection pain. To propose a protocol using a unique modality ...

journal_title：Dermatologic therapy

authors： Porat Ben Amy D,Kassem R

更新日期：2020-11-01 00:00:00

abstract：:As the first dermatological biological treatment, infliximab was first used in the treatment of psoriasis in 2001. Since that time many biological agents have come into use for dermatological diseases and developments in this area are still ongoing. The most important feature of biological treatments is that the treat...

journal_title：Dermatologic therapy

authors： Yavuz C

更新日期：2019-07-01 00:00:00

abstract：:Acne is known as a chronic inflammatory skin disease with sever adverse effects on quality of life in the patients. The increasing resistance to antibiotics has decreased their effectiveness in treating acne. As viable microbial dietary supplements, probiotics provide health benefits through fighting pathogens and mai...

journal_title：Dermatologic therapy

authors： Goodarzi A,Mozafarpoor S,Bodaghabadi M,Mohamadi M

更新日期：2020-05-01 00:00:00

abstract：:Ultrapotent topical corticosteroids and circumcision are usually effective for male genital lichen sclerosus (MGLSc); however, refractory cases are often referred to our Male Genital Dermatology Unit. Treatment with autologous platelet-rich plasma (TPRP) has recently been advocated as a safe and effective treatment op...

journal_title：Dermatologic therapy

authors： Navarrete J,Echarte L,Sujanov A,Guillones A,Vola M,Bunker CB,Agorio C,Touriño C

更新日期：2020-11-01 00:00:00

abstract：:Objective of this open, noninterventional, noncontrolled study was to investigate the tolerability and performance of a woad extract containing cream in subjects with dry, pruritic skin after twice daily application over 2 weeks. Assessments included sensorial characteristics, skin condition, pruritus (numeric rating ...

journal_title：Dermatologic therapy

authors： Forner C,Zeidler C,Stein P,Stössel E,Wefelmeier L,Peukert N,Isermann D,Ständer S

更新日期：2019-07-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established nonsurgical treatment for nodular basal cell carcinoma (nBCC). This study compares the clinical, histopathological, and immunohistochemical findings in recurrent nBCC after PDT versus pre-treatment (primary) nBCC. This retrospective study analyzed nodular BCCs treated with ...

journal_title：Dermatologic therapy

authors： Gracia-Cazaña T,Nicolás J,Cerro-Muñoz PA,González S,Juarranz Á,Gilaberte Y

更新日期：2021-01-13 00:00:00

abstract：:Alopecia areata (AA) is a common disease that results in nonscarring hair loss. Recently, tofacitinib (TOFA) has been a novel promising therapy for AA. The aim of this study is to determine the efficacy of oral TOFA treatment for alopecia areata (AA), and alopecia universalis (AU). Data of nine patients treated with o...

journal_title：Dermatologic therapy

authors： Akdogan N,Ersoy-Evans S,Doğan S,Atakan N

更新日期：2019-11-01 00:00:00

abstract：:Zoonoses are infectious diseases that can be transmitted from animals to humans. Transmission occurs directly or through vectors such as ticks, mosquitoes, or flies. The causative agents include bacteria, parasites, viruses, and fungi. Domestic pets and livestock, as well as wild animals, can be the source of disease....

journal_title：Dermatologic therapy

authors： Wilson M,Lountzis N,Ferringer T

更新日期：2009-07-01 00:00:00