Biologics in dermatology: What does the future hold?

abstract：:Epidermolytic acanthoma is an uncommon benign tumor with a predilection for the anogenital region, that is characterized histologically by epidermolytic hyperkeratosis. Most reported cases are asymptomatic while some are pruritic. Treatment of this condition is challenging and not well studied. We report a 55-year-old...

journal_title：Dermatologic therapy

authors： Tan GF,Tan ES,Tey HL

更新日期：2014-03-01 00:00:00

abstract：:Some studies have demonstrated that neurotransmitters are involved in the pathogenesis of numerous skin conditions, including psoriasis, addressing the close correlation between the skin and the central nervous system. There are reports showing psoriasis improvement after peripheral nervous system injury. In addition,...

journal_title：Dermatologic therapy

authors： González C,Franco M,Londoño A,Valenzuela F

更新日期：2020-11-01 00:00:00

abstract：:Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoria...

journal_title：Dermatologic therapy

authors： Jindal R,Chauhan P,Sethi S

更新日期：2020-12-05 00:00:00

abstract：:The highest efficacy of oral propranolol is for infantile hemangioma (IH) in the proliferative phase. Evaluation of the effectiveness of oral propranolol is less established when it is administered in late infancy following the proliferative phase. We aimed to assess the clinical outcomes of pediatric patients managed...

journal_title：Dermatologic therapy

authors： Kridin K,Pam N,Bergman R,Khamaysi Z

更新日期：2020-05-01 00:00:00

abstract：:The rise in popularity and demand for nonsurgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimize the potential for cross-contam...

journal_title：Dermatologic therapy

authors： Murthy R,Eccleston D,Mckeown D,Parikh A,Shotter S

更新日期：2020-10-17 00:00:00

abstract：:Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse cutaneous drug reaction with mortality up to 10%. It is a rare condition with risk varying between 1 in 1000 and 1 in 10 000 drug exposures. The aim of the study was to describe clinical features, management and drugs responsible for cau...

journal_title：Dermatologic therapy

authors： Sandhu S,Neema S,Vashisht D,Venugopal R,Sengupta P,Radhakrishnan S

更新日期：2020-12-14 00:00:00

abstract：:Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...

journal_title：Dermatologic therapy

authors： Asilian A,Kazemipour S,Mokhtari F,Iraji F,Shahmoradi Z,Mohaghegh F,Mozafarpoor S,Talakoub M

更新日期：2021-01-05 00:00:00

abstract：:The World Health Organization has recently defined the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections as a pandemic. The infection, which may cause a potentially very severe respiratory disease, now called coronavirus disease 2019 (COVID-19), has airborne transmission via droplets while less a...

journal_title：Dermatologic therapy

authors： Elsaie ML,Nada HA

更新日期：2020-09-01 00:00:00

abstract：:Studies on microcystic adnexal carcinoma (MAC) survival rates have been limited. This effort examines the association of patient demographics, treatment modalities, and tumor stage with overall survival (OS) in patients with MAC of the head and neck. All cases of MAC with primary sites of the skin of the head and neck...

journal_title：Dermatologic therapy

authors： Behbahani S,Yeh CJ,Pinto JO,Wassef D,Povolotskiy R,Joseph N,Lambert WC,Schwartz RA

更新日期：2020-11-18 00:00:00

abstract：:Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser...

journal_title：Dermatologic therapy

authors： Mu YZ,Jiang L,Yang H

更新日期：2019-11-01 00:00:00

abstract：:Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...

journal_title：Dermatologic therapy

authors： Kennemer C,Pavlidakey P,Sami N

更新日期：2017-07-01 00:00:00

abstract：:Vitiligo is a relatively common disorder characterized by areas of depigmented skin. It may be associated with social stigma and adversely affects the quality of life. Although many treatment options are available, none is curable. The search continues for an effective therapeutic option. New targeted options include ...

journal_title：Dermatologic therapy

authors： Agarwal K,Podder I,Kassir M,Vojvodic A,Schwartz RA,Wollina U,Valle Y,Lotti T,Rokni GR,Grabbe S,Goldust M

更新日期：2020-03-01 00:00:00

abstract：:Epidermolysis bullosa (EB) is a group of rare heterogeneous, genetic disorders. Currently, there is no effective pharmacological or genetic therapy for all EB subtypes. Dry extract from birch bark and betulin upregulate some pro-inflammatory mediators and downregulate others. The increase in pro-inflammatory cytokines...

journal_title：Dermatologic therapy

authors： Schwieger-Briel A,Ott H,Kiritsi D,Laszczyk-Lauer M,Bodemer C

更新日期：2019-07-01 00:00:00

abstract：:Pemphigus encompasses a group of chronic autoimmune blistering diseases of the skin and/or mucosa. Rituximab (RTX) has shown promising efficacy for the treatment of pemphigus in the past decade. Considering potential cardiac side effects, this study was conducted to assess the effects of RTX on electrocardiogram (ECG)...

journal_title：Dermatologic therapy

authors： Aidi S,Daneshpazhooh M,Eslami M,Azizpour A,Toosi R,Mollazadeh R

更新日期：2020-11-01 00:00:00

abstract：:Dialkylcarbamoylchloride (DACC)-coated cotton acetate dressing works directly through hydrophobic interaction to reduce the number of bacteria without the risk of resistance. It is easy to use and therefore expected to improve patient's compliance. This study aimed to assess the clinical efficacy of DACC-coated cotton...

journal_title：Dermatologic therapy

authors： Dwiyana RF,Gondokaryono SP,Rahardja JI,Arline Diana I,Yogya Y,Gunawan H

更新日期：2019-09-01 00:00:00

abstract：:Desquamative inflammatory vaginitis (DIV) is not a diagnosis in itself, and may be the presentation of a range of blistering disorders including pemphigus vulgaris, lichen planus and mucous membrane pemphigoid. The existence of an idiopathic subset of DIV remains controversial and is discussed in the present article. ...

journal_title：Dermatologic therapy

authors： Murphy R

更新日期：2004-01-01 00:00:00

abstract：:Pemphigus is a group of autoimmune diseases characterized by the formation of erosions and/or flaccid bullae of the skin and/or mucosae. The definition "drug-induced pemphigus" has been coined to indicate cases of pemphigus with clinical, histological and immunopathologic features similar to those of the idiopathic di...

journal_title：Dermatologic therapy

authors： Palleria C,Bennardo L,Dastoli S,Iannone LF,Silvestri M,Manti A,Nisticò SP,Russo E,De Sarro G

更新日期：2019-01-01 00:00:00

abstract：:Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...

journal_title：Dermatologic therapy

authors： Kara Polat A,Akın Belli A,Göre Karaali M,Koku Aksu AE

更新日期：2020-11-01 00:00:00

abstract：:Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR)...

journal_title：Dermatologic therapy

authors： Fawzy MM,Nofal A,Alakad R

更新日期：2020-11-01 00:00:00

abstract：:Surgery as treatment for local invasive cutaneous squamous cell carcinoma (cSCC) is not always feasible due to the age and/or the health status of patients. Thus, the investigation of new strategies to improve the quality of life of them is required. The aim of this work is to investigate two chemotherapy agents indiv...

journal_title：Dermatologic therapy

authors： Gil S,Yébenes M,Luelmo J,Alsina M,Sabés M

更新日期：2016-09-01 00:00:00

abstract：:Various adverse events (AEs) have been reported to occur at a high rate in patients treated with dabrafenib plus trametinib (D + T) combination therapy. Among such AEs, the incidence of pyrexia was highest among the series of AEs in patients treated with D + T combination therapy. Although little is known about the me...

journal_title：Dermatologic therapy

authors： Amagai R,Fujimura T,Muto Y,Kambayashi Y,Furudate S,Ohuchi K,Okuma T,Hashimoto A,Aiba S

更新日期：2020-11-14 00:00:00

abstract：:Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...

journal_title：Dermatologic therapy

authors： Barrett ME,Heller MM,Fullerton Stone H,Murase JE

更新日期：2013-07-01 00:00:00

abstract：:The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...

journal_title：Dermatologic therapy

authors： Rossi R,Assad GB,Buggiani G,Lotti T

更新日期：2008-09-01 00:00:00

abstract：:Basal cell carcinoma (BCC) is the most common malignancy in Caucasians, and its incidence is increasing. Most BCCs are treated surgically, nevertheless surgery is not an effective treatment for locally advanced or metastatic BCC. Alterations in hedgehog signaling pathway, a key regulator of cell growth and differentia...

journal_title：Dermatologic therapy

authors： Spallone G,Sollena P,Ventura A,Fargnoli MC,Gutierrez C,Piccerillo A,Tambone S,Bianchi L,Peris K

更新日期：2019-11-01 00:00:00

abstract：:Many traditional Chinese medicine compositions can moisturize the skin and utilize in cosmetics. Using a combination of Chinese Medicine Materials and guided by Traditional Chinese Medicine principles, this study selected Echinacea purpurea to protect the skin barrier, Dendrobium nobile to clear heat and promote fluid...

journal_title：Dermatologic therapy

authors： Meng H,Li J,Dong Y,He Y,Ren H,Liu Y,Qu Z,Zhang W,Zhang L,Bao T,Yi F

更新日期：2020-11-01 00:00:00

abstract：:Large difficult to heal ulcers of various etiologies carry a high morbidity and mortality rate. Becaplermin is a recombinant platelet-derived growth factor approved for treatment of diabetic ulcers. In this two-case series, we report the use of becaplermin in the treatment of ulcers due to (i) calciphylaxis, an often ...

journal_title：Dermatologic therapy

authors： Twu O,Mednik S,Scumpia P,Doaty S,Worswick S

更新日期：2016-03-01 00:00:00

abstract：:Past studies have reported associations between psoriasis, metabolic syndrome, and atherosclerotic cardiovascular disease. According to studies, N-terminal pro B-type natriuretic peptide (NT-proBNP) is a useful screening test for cardiac disease. We examined the serum NT-proBNP level in patients with psoriasis and com...

journal_title：Dermatologic therapy

authors： Shahidi-Dadras M,Niknezhad N,Niknejad N,Zargari O

更新日期：2019-05-01 00:00:00

abstract：:Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

journal_title：Dermatologic therapy

authors： Accordino RE,Engler D,Ginsburg IH,Koo J

更新日期：2008-01-01 00:00:00

abstract：:Management of keloid is difficult, so there is always a need for adequate and effective therapy. In this study, we explored and compared the efficacy and synergistic effect of combined intralesional radiofrequency (RF) and intralesional triamcinolone acetonide (TAC) with intralesional triamcinolone acetonide alone in ...

journal_title：Dermatologic therapy

authors： Kaushal V,Kumar S,Brar BK,Singh A

更新日期：2020-11-01 00:00:00

abstract：:It has been reported that dermatology practices may be a vector for SARS-CoV-2 transmission and elective cases should be postponed during the pandemic period. In this context, studies on the change of patient profile in Dermatology outpatient clinic have been conducted. However, there was no study in the literature ab...

journal_title：Dermatologic therapy

authors： Temiz SA,Dursun R,Daye M,Ataseven A

更新日期：2020-09-01 00:00:00