Abstract:
:Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR), Candida antigen, and purified protein derivative (PPD) in the treatment of multiple plane warts. The study included 120 patients who were randomly assigned to three groups, 40 patients in each group. Each agent was injected intralesionally at a dose of 0.1 mL into the largest wart at 2-week intervals until complete clearance or for a maximum of five sessions. Complete clearance of warts was observed in 55% of the PPD group, in 70% of the Candida antigen group, and in 62.5% of the MMR group. No statistically significant difference in the therapeutic response was found between the three groups. Intralesional antigen immunotherapy seems to be a promising well-tolerated and effective therapeutic option for the treatment of multiple plane warts, with relatively higher efficacy of Candida antigen.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Fawzy MM,Nofal A,Alakad Rdoi
10.1111/dth.13807subject
Has Abstractpub_date
2020-11-01 00:00:00pages
e13807issue
6eissn
1396-0296issn
1529-8019journal_volume
33pub_type
杂志文章abstract::The isotretinoin registry has arrived. It has a lofty goal of preventing all isotretinoin pregnancies. How we got to this point and what the registry means to prescribers and patients have many dermatologists confused and concerned. Will it be burdensome, will it preclude the use in most offices of this most important...
journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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pub_type: 杂志文章,评审
doi:10.1111/dth.12745
更新日期:2019-01-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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