Recalcitrant trametinib-induced paronychia treated successfully with topical timolol in a pediatric patient.

Abstract:

:Paronychia has been described as a side effect in patients undergoing treatment with MEK (mitogen activated protein kinase enzyme) inhibitors. It is usually a recurrent condition that can have a significant impact in the quality of life. Topical beta blocker treatment has been described as an effective therapy in antineoplastic-induced pyogenic granulomas and in antineoplastic-induced paronychia. We describe the first case treated with topical timolol for a trametinib-induced paronychia in a pediatric patient that allowed to continue the third line antineoplastic therapy for his glioma.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Martínez-de-Espronceda I,Bernabeu-Wittel J,Azcona M,Monserrat MT

doi

10.1111/dth.13164

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

e13164

issue

1

eissn

1396-0296

issn

1529-8019

journal_volume

33

pub_type

信件
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