Drug therapy in pediatrics: a developing field.

abstract：:Maffucci syndrome is characterized by multiple benign vascular anomalies and enchondromas present on the distal extremities. Effective treatment options are currently not available for Maffucci syndrome-associated vascular lesions. Sirolimus is a mTOR pathway inhibitor, and has been tried successfully in the treatment...

journal_title：Dermatologic therapy

authors： Gupta V,Mridha AR,Khaitan BK

更新日期：2019-05-01 00:00:00

abstract：:Onychomycosis is an important medical disorder affecting both health and quality of life of patients. This study was done to compare the efficacy of CO2 laser in combination with topical tioconazole versus CO2 laser only versus topical tioconazole alone in onychomycosis. A total of 120 patients with onychomycosis were...

journal_title：Dermatologic therapy

authors： Zaki AM,Abdo HM,Ebadah MA,Ibrahim SM

更新日期：2020-01-01 00:00:00

abstract：:This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by ...

journal_title：Dermatologic therapy

authors： McElwee KJ

更新日期：2008-07-01 00:00:00

abstract：:The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway has been linked to the pathogenesis of many inflammatory skin diseases; however, the role of JAKs in the pathogenesis of acne vulgaris has not been previously elucidated. We aimed to analyze the cutaneous expression of JAK1/...

journal_title：Dermatologic therapy

authors： Awad SM,Tawfik YM,El-Mokhtar MA,El-Gazzar AF,Abdel Motaleb AA

更新日期：2020-11-19 00:00:00

abstract：:Pemphigus encompasses a group of chronic autoimmune blistering diseases of the skin and/or mucosa. Rituximab (RTX) has shown promising efficacy for the treatment of pemphigus in the past decade. Considering potential cardiac side effects, this study was conducted to assess the effects of RTX on electrocardiogram (ECG)...

journal_title：Dermatologic therapy

authors： Aidi S,Daneshpazhooh M,Eslami M,Azizpour A,Toosi R,Mollazadeh R

更新日期：2020-11-01 00:00:00

abstract：:Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser...

journal_title：Dermatologic therapy

authors： Mu YZ,Jiang L,Yang H

更新日期：2019-11-01 00:00:00

abstract：:Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...

journal_title：Dermatologic therapy

authors： Bar-Ilan E,Koren A,Shehadeh W,Mashiah J,Sprecher E,Artzi O

更新日期：2020-01-01 00:00:00

abstract：:Psoriasis of the scalp, face, intertriginous areas, genitals, hands, feet, and nails is often underdiagnosed, and disease management can be challenging. Despite the small surface area commonly affected by psoriasis in these locations, patients have disproportionate levels of physical impairment and emotional distress....

journal_title：Dermatologic therapy

authors： Merola JF,Qureshi A,Husni ME

更新日期：2018-05-01 00:00:00

abstract：:Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2014-07-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are medication-induced in most instances. While the clinical manifestations of SJS and TEN are well-defined, the optimal treatment for these disorders is not. Case reports have shown benefit with the use of a variet...

journal_title：Dermatologic therapy

authors： Worswick S,Cotliar J

更新日期：2011-03-01 00:00:00

abstract：:Melasma is a hard-to-manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064-nm low-fluence Q-switched...

journal_title：Dermatologic therapy

authors： Abdel Hay R,Mohammed FN,Sayed KS,Abd El Fattah NA,Ibrahim S

更新日期：2020-07-01 00:00:00

abstract：:Surgery as treatment for local invasive cutaneous squamous cell carcinoma (cSCC) is not always feasible due to the age and/or the health status of patients. Thus, the investigation of new strategies to improve the quality of life of them is required. The aim of this work is to investigate two chemotherapy agents indiv...

journal_title：Dermatologic therapy

authors： Gil S,Yébenes M,Luelmo J,Alsina M,Sabés M

更新日期：2016-09-01 00:00:00

abstract：:Omalizumab is a monoclonal antibody, targeting Fc receptor of IgE, approved for the treatment of allergic asthma and chronic spontaneous urticaria. Its utility in atopic dermatitis appears controversial from data in literature since the molecule is well tolerated but it seems less effective than other medications used...

journal_title：Dermatologic therapy

authors： Iannelli M,Caminiti L,Vaccaro M,Marafioti I,Spinuzza A,Panasiti I,Barbalace A,Crisafulli G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：:Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing count...

journal_title：Dermatologic therapy

authors： Powers JG,Morton LM,Phillips TJ

更新日期：2013-05-01 00:00:00

abstract：:Cumulative exposure to ultraviolet radiation (UVR) increases the risk of developing skin cancer, particularly squamous cell carcinoma and basal cell carcinoma. Thus, the need for protection from the sun is widely advocated, but consumers generally associate such protection with the occasional extreme exposure and tend...

journal_title：Dermatologic therapy

authors： Nole G,Johnson AW

更新日期：2004-01-01 00:00:00

abstract：:Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...

journal_title：Dermatologic therapy

authors： Çetinarslan T,Evrenos MK,Bilaç C,Özyurt B,Türel Ermertcan A

更新日期：2020-11-01 00:00:00

abstract：:Lichen planus is considered a T cell-mediated immunological disease. Even mast cells may contribute to the pathogenesis of the disease. Keratinocytes of the basal layer of the skin and/or the hair follicle may represent the "target/victim" of an immune aggression, determining the destruction of the hair follicle and t...

journal_title：Dermatologic therapy

authors： d'Ovidio R,Rossi A,Di Prima TM

更新日期：2010-09-01 00:00:00

abstract：:Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...

journal_title：Dermatologic therapy

authors： Kara Polat A,Akın Belli A,Göre Karaali M,Koku Aksu AE

更新日期：2020-11-01 00:00:00

abstract：:COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and other potential drugs have been studied for COVID19 treatment. We reviewed t...

journal_title：Dermatologic therapy

authors： Türsen Ü,Türsen B,Lotti T

更新日期：2020-07-01 00:00:00

abstract：:Prayer marks are asymptomatic callosities resulting from repeated, extended pressure, and friction exerted on bony prominences when praying on hard ground. A 41-year-old woman with ulcerative colitis treated with infliximab was referred to our clinic due to skin changes on her feet that were suspected to be drug erupt...

journal_title：Dermatologic therapy

authors： Fosse N,Rast AC,Kammermann A,Sonderegger J,Navarini A,Goldust M,Brandt O,Mueller SM

更新日期：2020-01-01 00:00:00

abstract：:Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to...

journal_title：Dermatologic therapy

authors： Ertugrul G,Ertugrul S,Soylemez E

更新日期：2020-07-01 00:00:00

abstract：:Acne is known as a chronic inflammatory skin disease with sever adverse effects on quality of life in the patients. The increasing resistance to antibiotics has decreased their effectiveness in treating acne. As viable microbial dietary supplements, probiotics provide health benefits through fighting pathogens and mai...

journal_title：Dermatologic therapy

authors： Goodarzi A,Mozafarpoor S,Bodaghabadi M,Mohamadi M

更新日期：2020-05-01 00:00:00

abstract：:The ultraviolet (UV) light spectrum has long been known to induce biologic effect on the skin. For a large number of cutaneous disorders, phototherapy and photochemotherapy are effective therapeutic options with excellent safety profiles and well-documented side effects. Despite their ease of administration and benefi...

journal_title：Dermatologic therapy

authors： Sage RJ,Lim HW

更新日期：2010-01-01 00:00:00

abstract：:Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...

journal_title：Dermatologic therapy

authors： Kennemer C,Pavlidakey P,Sami N

更新日期：2017-07-01 00:00:00

abstract：:Verrucas are often recalcitrant to conventional cryotherapy. Since 1970, intralesional bleomycin has been used off-label by dermatologists. But in some cases, the results of intralesional bleomycin were disappointing. Vincristine is a well-known vinca alkaloid antiblastic drug that has been used for treating hematolog...

journal_title：Dermatologic therapy

authors： Lee JR,Youn JH,Roh JY

更新日期：2011-05-01 00:00:00

abstract：:Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoria...

journal_title：Dermatologic therapy

authors： Jindal R,Chauhan P,Sethi S

更新日期：2020-12-05 00:00:00

abstract：:Febrile ulcero-necrotic Mucha-Habermann disease (FUMHD) is a rare subtype of pityriasis lichenoides et varioliformis acuta (only 41 cases described to date), characterized by an acute onset of ulcero-necrotic papules accompanied by high fever and severe constitutional symptoms. We report a case of a 23-year-old man wi...

journal_title：Dermatologic therapy

authors： Marenco F,Fava P,Fierro MT,Quaglino P,Bernengo MG

更新日期：2010-07-01 00:00:00

abstract：:Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglan...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2016-11-01 00:00:00

abstract：:Diphenylcyclopropenone (DPCP) immunotherapy has been shown to be efficacious for the treatment of warts, especially periungual warts for which destructive techniques are limited. However, factors affecting the duration of treatment of periungual warts have not been studied. A total of 61 patients with periungual warts...

journal_title：Dermatologic therapy

authors： Park HK,Kim JS

更新日期：2016-03-01 00:00:00

abstract：:Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...

journal_title：Dermatologic therapy

authors： Zackheim HS

更新日期：2003-01-01 00:00:00