Activation of Janus kinase signaling pathway in acne lesions.

abstract：:Although acne is not an infectious disease, oral antibiotics have remained a mainstay of treatment over the last 40 years. The anti-inflammatory properties of oral antibiotics, particularly the tetracyclines, are efficacious in treating inflammatory acne lesions. Common prescribing practices in Dermatology exert signi...

journal_title：Dermatologic therapy

authors： Farrah G,Tan E

更新日期：2016-09-01 00:00:00

abstract：:Large difficult to heal ulcers of various etiologies carry a high morbidity and mortality rate. Becaplermin is a recombinant platelet-derived growth factor approved for treatment of diabetic ulcers. In this two-case series, we report the use of becaplermin in the treatment of ulcers due to (i) calciphylaxis, an often ...

journal_title：Dermatologic therapy

authors： Twu O,Mednik S,Scumpia P,Doaty S,Worswick S

更新日期：2016-03-01 00:00:00

abstract：:Psychiatric symptoms in dermatology practice are increasingly being recognized. The use of psychiatric medications by dermatologist is dealt with caution and uncertainty in several psychodermatological conditions. Several skin conditions are associated with anxiety, depression, and obsessive-compulsive symptoms. Some ...

journal_title：Dermatologic therapy

authors： Jafferany M,Stamu-O'Brien C,Mkhoyan R,Patel A

更新日期：2020-05-01 00:00:00

abstract：:Tattoos have long become a part of human civilization. However, as the number of people who get tattoos increases, so is the number of people who wish to have their tattoos removed. Compared to other methods, laser-based devices are associated with the best efficacy and least side effects in tattoo removal. Lack of un...

journal_title：Dermatologic therapy

authors： Kurniadi I,Tabri F,Madjid A,Anwar AI,Widita W

更新日期：2020-10-17 00:00:00

abstract：:Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...

journal_title：Dermatologic therapy

authors： Juzlova K,Votrubova J,Kacerovska D,Lukas M,Bortlik M,Rohacova H,Nohynkova E,Vojackova N,Fialova J,Hercogova J

更新日期：2014-05-01 00:00:00

abstract：:Keloid often recur after treatment, and recent studies in keloid management favor the combination therapy of laser-assisted drug delivery over monotherapy. Unfortunately, the previous researches lack long-term follow-up. In this prospective study, 41 individuals with refractory keloids underwent eight treatment sessio...

journal_title：Dermatologic therapy

authors： Wang J,Wu J,Xu M,Gao Q,Chen B,Wang F,Song H

更新日期：2020-11-01 00:00:00

abstract：:Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

journal_title：Dermatologic therapy

authors： Accordino RE,Engler D,Ginsburg IH,Koo J

更新日期：2008-01-01 00:00:00

abstract：:The safety of methotrexate in psoriasis patients with metabolic syndrome could be argued because of increased risk of liver toxicity. The aim of the study was to investigate the safety of methotrexate compared with secukinumab in psoriasis patients with metabolic syndrome. A controlled, open trial in psoriasis patient...

journal_title：Dermatologic therapy

authors： Gisondi P,Bellinato F,Bruni M,De Angelis G,Girolomoni G

更新日期：2020-11-01 00:00:00

abstract：:Generalized eruptive keratoacanthoma, is considered a serious condition because the eruptions are diffuse, persistent, and recurrent. Constant pruritus, visceral neoplasms, and unsatisfactory response to treatment are ominous prognostic factors. Even if skin cancers are usually well controlled with surgical and/or rad...

journal_title：Dermatologic therapy

authors： Ribero S,Balagna E,Sportoletti Baduel E,Picciotto F,Sanlorenzo M,Fierro MT,Quaglino P,Macripo G

更新日期：2016-09-01 00:00:00

abstract：:Verrucas are often recalcitrant to conventional cryotherapy. Since 1970, intralesional bleomycin has been used off-label by dermatologists. But in some cases, the results of intralesional bleomycin were disappointing. Vincristine is a well-known vinca alkaloid antiblastic drug that has been used for treating hematolog...

journal_title：Dermatologic therapy

authors： Lee JR,Youn JH,Roh JY

更新日期：2011-05-01 00:00:00

abstract：:Hand dermatitis is a common skin condition that often has a chronic and/or relapsing clinical course. Several clinical forms of hand dermatitis have been described, including contact (i.e., allergic and irritant), hyperkeratotic (i.e., psoriasiform or tylotic), frictional, nummular, atopic, pompholyx (i.e., dyshidrosi...

journal_title：Dermatologic therapy

authors： Warshaw EM

更新日期：2004-01-01 00:00:00

abstract：:Vitiligo is quite a common hypopigmentary disorder, which may affect both children and adults with important psychological effects due to the well-known leopard skin-like appearance. The authors summarize in the present study the published evidence on vitiligo with particular interest on the controversial aspects of t...

journal_title：Dermatologic therapy

authors： Lotti T,Gianfaldoni S,Valle Y,Rovesti M,Feliciano C,Satolli F

更新日期：2019-01-01 00:00:00

abstract：:Melasma is a hard-to-manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064-nm low-fluence Q-switched...

journal_title：Dermatologic therapy

authors： Abdel Hay R,Mohammed FN,Sayed KS,Abd El Fattah NA,Ibrahim S

更新日期：2020-07-01 00:00:00

abstract：:Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...

journal_title：Dermatologic therapy

authors： Taraz M,Niknam S,Ehsani AH

更新日期：2017-05-01 00:00:00

abstract：:The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...

journal_title：Dermatologic therapy

authors： Passanisi S,Arasi S,Caminiti L,Crisafulli G,Salzano G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：:Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...

journal_title：Dermatologic therapy

authors： Kara Polat A,Akın Belli A,Göre Karaali M,Koku Aksu AE

更新日期：2020-11-01 00:00:00

abstract：:Lasers are considered the most efficient methods for hair reduction. The goal of these devices is to provide long-term effects without adverse reactions. This is a randomized split-body controlled study on body hair removal and pseudofolliculitis (PFC) treatment, comparing the standard single pass (SP) emission with t...

journal_title：Dermatologic therapy

authors： Bonan P,Troiano M,Verdelli A

更新日期：2020-11-01 00:00:00

abstract：:Epidermolysis Bullosa (EB) is a rare group of diseases caused by genetic variants in skin structural proteins. EB is characterized by varying degrees of skin fragility, blisters and impaired wound healing, and is classified based on the ultrastructural levels of skin cleavage-simplex, junctional, dystrophic, and Kindl...

journal_title：Dermatologic therapy

authors： Bartolo J,Farricha V,Carvalhal S,Moura C,Abecasis N

更新日期：2020-11-01 00:00:00

abstract：:This article refers to papulosquamous diseases that are seen in the elderly. Many of these diseases are complex to diagnose due to the fact that they are difficult to identify, because they may resemble a similar disorder, which can be misleading. The problem that is frequently seen with these diseases is that they ar...

journal_title：Dermatologic therapy

authors： Norman RA,Blanco PM

更新日期：2003-01-01 00:00:00

abstract：:Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds...

journal_title：Dermatologic therapy

authors： Smolle J

更新日期：2003-01-01 00:00:00

abstract：:Diphenylcyclopropenone (DPCP) immunotherapy has been shown to be efficacious for the treatment of warts, especially periungual warts for which destructive techniques are limited. However, factors affecting the duration of treatment of periungual warts have not been studied. A total of 61 patients with periungual warts...

journal_title：Dermatologic therapy

authors： Park HK,Kim JS

更新日期：2016-03-01 00:00:00

abstract：:A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...

journal_title：Dermatologic therapy

authors： Hussain K,Gkini MA,Taylor R,Shinhmar S,Bewley A

更新日期：2018-11-01 00:00:00

abstract：:Acute urticaria is a self-limited cutaneous condition marked by transient, erythematous, and pruritic wheals. It is a hypersensitivity response that is often secondary to infection, medications, or food allergies in children. In contrast, the urticarial "mimickers" described in this review article are often seen in th...

journal_title：Dermatologic therapy

authors： Mathur AN,Mathes EF

更新日期：2013-11-01 00:00:00

abstract：:The development of effective and well-tolerated biologic therapies has advanced the management of psoriasis by enabling clinicians to treat underlying disease mechanisms. Biologics approved for the treatment of moderate-to-severe psoriasis include three tumor necrosis factor alpha inhibitors and an interleukin-12/inte...

journal_title：Dermatologic therapy

authors： Gaspari AA,Tyring S

更新日期：2015-07-01 00:00:00

abstract：:Psoriasis impacts the quality of life (QoL) by disrupting overall health and social life. Thus, the use of a QoL evaluation item is crucial in assessing a therapeutic regimen. Also, faster improvements in QoL lead to better patient compliance, but very few studies compare psoriasis traditional and biologic therapies t...

journal_title：Dermatologic therapy

authors： Pistone G,Gurreri R,Tilotta G,Caruso P,Curiale S,Bongiorno MR

更新日期：2019-09-01 00:00:00

abstract：:Itch is an extremely frequent and enervating symptom of many diseases. Current anti-itch therapy, which is based almost exclusively on an "immunocentric" viewpoint, is often unsatisfactory. Recent studies show that this symptom is in fact the result of a complex interplay among skin, nervous system, endocrine system, ...

journal_title：Dermatologic therapy

authors： Guarneri C,Terranova M,Terranova G,Guarneri F

更新日期：2005-07-01 00:00:00

abstract：:During the past 20 years, tremendous progress has been made in our understanding of the molecular basis of many genetic skin conditions. The translation of these laboratory findings into effective therapies for affected individuals has been slow, however, in large part due to the risk of carcinogenesis from random vir...

journal_title：Dermatologic therapy

authors： Lai-Cheong JE,Elias PM,Paller AS

更新日期：2013-01-01 00:00:00

abstract：:Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...

journal_title：Dermatologic therapy

authors： Barrett ME,Heller MM,Fullerton Stone H,Murase JE

更新日期：2013-07-01 00:00:00

abstract：:Merkel cell carcinoma is rare and aggressive skin cancer, which occurrence is linked to exposure to ultraviolet light and the Merkel-cell polyomavirus. In recent years, significant progress in understanding the mechanism of Merkel cell carcinoma pathogenesis has been observed. This neoplasm often expresses PD-L1, and ...

journal_title：Dermatologic therapy

authors： Kwiatkowska D,Reich A

更新日期：2020-05-01 00:00:00

abstract：:The present authors report the case of a 9-year-old boy affected by psoriasis, juvenile psoriatic arthritis, enthesitis, and celiac disease. The signs and symptoms of the different comorbidities appeared at different times in the clinical history, complicating the overall diagnostic and therapeutic procedures. Coopera...

journal_title：Dermatologic therapy

authors： Prignano F,Bonciani D,Bandinelli F,Matucci Cerinic M,Lotti T

更新日期：2010-03-01 00:00:00