New and emerging biologic therapies for moderate-to-severe plaque psoriasis: mechanistic rationales and recent clinical data for IL-17 and IL-23 inhibitors.

abstract：:Until now, there have only been two cases describing the coexistence of angiolymphoid hyperplasia with eosinophilia (ALHE) and Kimura's disease in one patient. Herein, we report the previous case of recurrent ALHE and Kimura's disease that was successfully treated with surgery. ...

journal_title：Dermatologic therapy

authors： Jun R,Liu XK,Zeng K

更新日期：2014-01-01 00:00:00

abstract：:Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...

journal_title：Dermatologic therapy

authors： Johansen MB,Jemec GBE,Fabricius S

更新日期：2019-09-01 00:00:00

abstract：:Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...

journal_title：Dermatologic therapy

authors： Zackheim HS

更新日期：2003-01-01 00:00:00

abstract：:Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoria...

journal_title：Dermatologic therapy

authors： Jindal R,Chauhan P,Sethi S

更新日期：2020-12-05 00:00:00

abstract：:Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...

journal_title：Dermatologic therapy

authors： Barrett ME,Heller MM,Fullerton Stone H,Murase JE

更新日期：2013-07-01 00:00:00

abstract：:The skin plays a critical role in the detection of internal malignances. Cutaneous signs of these disorders afford clinicians opportunities for early diagnosis and treatment. We aim to succinctly review the recognition, diagnosis, and treatment of selected cutaneous paraneoplastic diseases. Skin disorders that may be ...

journal_title：Dermatologic therapy

authors： Abreu Velez AM,Howard MS

更新日期：2010-11-01 00:00:00

abstract：:Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been an open debate on the impact of biological drugs used in the treatment of psoriasis. To define whether patients under treatment with biologics suffer from increased morbidity and mortality from COVID-19, compared to psoriatic patients ...

journal_title：Dermatologic therapy

authors： Brazzelli V,Isoletta E,Barak O,Barruscotti S,Vassallo C,Giorgini C,Michelerio A,Tomasini CF,Musella V,Klersy C

更新日期：2020-11-01 00:00:00

abstract：:Psoriasis is a common dermatosis affecting the skin, mucosal surfaces, and cutaneous adnexa, and joints and bones can be involved at some degree in the clinical features of the disease, configuring psoriatic arthritis. Moderate to severe psoriasis has a high impact on quality of life and requires an integrated and lon...

journal_title：Dermatologic therapy

authors： Prignano F,Buggiani G,Lotti T

更新日期：2008-10-01 00:00:00

abstract：:Genital ulcer disease (GUD) constitutes a major public health problem. Most of them are the result of sexually transmitted diseases. Genital herpes, syphilis, lymphogranuloma venereum, granuloma venereum, or chancroid are the commonly encountered GUD. The treatment modalities for these disorders have changed with adve...

journal_title：Dermatologic therapy

authors： Kaliaperumal K

更新日期：2008-05-01 00:00:00

abstract：:Alopecia areata (AA) is a common disease that results in nonscarring hair loss. Recently, tofacitinib (TOFA) has been a novel promising therapy for AA. The aim of this study is to determine the efficacy of oral TOFA treatment for alopecia areata (AA), and alopecia universalis (AU). Data of nine patients treated with o...

journal_title：Dermatologic therapy

authors： Akdogan N,Ersoy-Evans S,Doğan S,Atakan N

更新日期：2019-11-01 00:00:00

abstract：:Tumor necrosis-alpha (TNF-alpha) has been implicated in many forms of inflammation and is an end-stage product of the inflammatory cytokine cascade. It is an inducer of inflammation and is involved in many cutaneous and systemic inflammatory diseases. The development of agents that block the effects of TNF-alpha has a...

journal_title：Dermatologic therapy

authors： Jackson JM

更新日期：2007-07-01 00:00:00

abstract：:Clinical research plays a very important role in the development of drugs and devices, including those for wound healing. The process of initiating a clinical trial can be rather daunting, particularly with the ever-increasing regulatory hurdles. Many clinicians are generally either not trained or have limited knowled...

journal_title：Dermatologic therapy

authors： Carson PA

更新日期：2006-11-01 00:00:00

abstract：:Zoonoses are infectious diseases that can be transmitted from animals to humans. Transmission occurs directly or through vectors such as ticks, mosquitoes, or flies. The causative agents include bacteria, parasites, viruses, and fungi. Domestic pets and livestock, as well as wild animals, can be the source of disease....

journal_title：Dermatologic therapy

authors： Wilson M,Lountzis N,Ferringer T

更新日期：2009-07-01 00:00:00

abstract：:Plantar warts can cause pain near the toes and the sole of the foot and may result in referral for treatment. This study was aimed at comparing 40% trichloroacetic acid (TCA) and cryotherapy (Cryo) for the treatment of plantar warts. This single-blind, randomized clinical trial was performed on 60 subjects presenting ...

journal_title：Dermatologic therapy

authors： Karrabi M,Kheirkhah M,Shahrestanaki E,Thomas S,Sahebkar M

更新日期：2020-07-01 00:00:00

abstract：:Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramati...

journal_title：Dermatologic therapy

authors： Alamri A,Alsenaid A,Ruzicka T,Wolf R

更新日期：2016-05-01 00:00:00

abstract：:Lasers and other light sources are popular treatment options for facial rejuvenation in recent years. In this study, we aimed to compare the efficacy and safety of fractional radiofrequency (RF) and fractional Erbium: YAG (Er:YAG) laser for facial and neck skin wrinkles, objectively. Three hundred and thirty-three pat...

journal_title：Dermatologic therapy

authors： Serdar ZA,Tatlıparmak A

更新日期：2019-09-01 00:00:00

abstract：:Treatment of severe psoriasis (PsO) in organ transplant (OT) patients is difficult. In fact, systemic drugs used for PsO therapy can be detrimental to transplanted organs and/or can increase the risk of serious infections in subjects already taking antireject medicines. Current guidelines fail to give indications on h...

journal_title：Dermatologic therapy

authors： Lora V,Graceffa D,De Felice C,Morrone A,Bonifati C

更新日期：2019-05-01 00:00:00

abstract：:Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function. The study objective was to investigate short-term and long-term effects of two emollients on symptoms and skin barrier functions in xerotic eczema. Randomized, double-blind, study enrolling females/males, with b...

journal_title：Dermatologic therapy

authors： Simon D,Nobbe S,Nägeli M,Barysch M,Kunz M,Borelli S,Hasan-Ali O,Wildi E,Gasser UE

更新日期：2018-11-01 00:00:00

abstract：:To date, the geographical distribution and global trends of search activities on psoriasis and atopic eczema on Google and YouTube are widely unknown. The aim of this study was to identify geographic and temporal trends in YouTube and Google search activities for psoriasis and atopic eczema. We used specific filter se...

journal_title：Dermatologic therapy

authors： Hongler VNS,Navarini A,Brandt O,Goldust M,Mueller SM

更新日期：2020-07-01 00:00:00

abstract：:This article refers to papulosquamous diseases that are seen in the elderly. Many of these diseases are complex to diagnose due to the fact that they are difficult to identify, because they may resemble a similar disorder, which can be misleading. The problem that is frequently seen with these diseases is that they ar...

journal_title：Dermatologic therapy

authors： Norman RA,Blanco PM

更新日期：2003-01-01 00:00:00

abstract：:The purpose of the work was to assess changes in chemerin and irisin levels in women with diagnosed intrahepatic cholestasis of pregnant women treated with ursodeoxycholic acid. The study group consisted of 50 patients with diagnosed and confirmed intrahepatic cholestasis of pregnant women at 24-25 weeks of pregnancy ...

journal_title：Dermatologic therapy

authors： Dąbrowski K,Kierach R,Grabarek BO,Boroń D,Kukla M

更新日期：2020-03-01 00:00:00

abstract：:The Coronavirus Disease 2019 (COVID-19) outbreak significantly affected the clinical practice in hospitals and the management of many diseases. The aim of this study was to evaluate the effect of pandemic-related factors on the severity and course of chronic urticaria (CU). A total of 194 CU patients who were on regul...

journal_title：Dermatologic therapy

authors： Erdem Y,Polat Ekinci A,Altunay IK,Sivaz O,Inal S,Gokalp MO,Pehlivan G,Özkaya E

更新日期：2020-12-10 00:00:00

abstract：:Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO(2) laser treatment shows peculiar effects in the skin, mainly due to its ability of modula...

journal_title：Dermatologic therapy

authors： Buggiani G,Tsampau D,Krysenka A,De Giorgi V,Hercogová J

更新日期：2012-11-01 00:00:00

abstract：:Lichen planus is considered a T cell-mediated immunological disease. Even mast cells may contribute to the pathogenesis of the disease. Keratinocytes of the basal layer of the skin and/or the hair follicle may represent the "target/victim" of an immune aggression, determining the destruction of the hair follicle and t...

journal_title：Dermatologic therapy

authors： d'Ovidio R,Rossi A,Di Prima TM

更新日期：2010-09-01 00:00:00

abstract：:The condition of most patients with hyperhidrosis (HH) is known to worsen with increased temperature. However, most prior studies of oral glycopyrrolate (OGly) for the treatment of HH have assumed a stable treatment protocol, without taking into account seasonal variations in temperature. The main aim of this study is...

journal_title：Dermatologic therapy

authors： Garcia-Souto F,Del Boz J,Polo-Padillo J

更新日期：2020-11-01 00:00:00

abstract：:Maintaining the health of dermal fibroblast cells and controlling their growth and proliferation would directly affect the health of skin tissues. The present study encompassed three control and three experimental specimens, which were different in terms of the duration of exposure to electromagnetic field (EMF) and i...

journal_title：Dermatologic therapy

authors： Naghibzadeh M,Gholampour S,Naghibzadeh M,Sadeghian-Nodoushan F,Nikukar H

更新日期：2020-07-01 00:00:00

abstract：:The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...

journal_title：Dermatologic therapy

authors： Passanisi S,Arasi S,Caminiti L,Crisafulli G,Salzano G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:The rise in popularity and demand for nonsurgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimize the potential for cross-contam...

journal_title：Dermatologic therapy

authors： Murthy R,Eccleston D,Mckeown D,Parikh A,Shotter S

更新日期：2020-10-17 00:00:00

abstract：:In view of the new viral COVID-19 pandemic, the fungal Candida auris epidemic still in progress worldwide highlights non-Candida albicans candidal infections. We describe an immunocompetent woman with a cutaneous manifestation of Candida parasilopsis fungemia, a prominent eschar, which proved to be the nidus for the c...

journal_title：Dermatologic therapy

authors： Schwartz RA,Kapila R

更新日期：2020-07-01 00:00:00