Abstract:
:The Coronavirus Disease 2019 (COVID-19) outbreak significantly affected the clinical practice in hospitals and the management of many diseases. The aim of this study was to evaluate the effect of pandemic-related factors on the severity and course of chronic urticaria (CU). A total of 194 CU patients who were on regular follow-up, were enrolled in the study. The disease activity was assessed by means of the weekly urticaria activity score (UAS7) and urticaria control test (UCT). Patients were divided into two subgroups according to their disease aggravation as "aggravated" and "non-aggravated". Two groups were compared in terms of demographic, clinical, COVID-19-associated parameters, and parameters related with the effect of COVID-19 pandemic on CU management. The omalizumab use was statistically higher (P = .017), and the systemic corticosteroid use was statistically lower (P = .025) in the "aggravated" group. Adherence to quarantine was significantly lower in the "aggravated" group (P = .027). 173 patients (89.2%) were unable to contact a dermatologist during the pandemic. Among 186 patients who received treatment for CU before the pandemic, 48 (25.8%) did not continue the existing treatment during the pandemic. CU aggravated in one patient with COVID-19 and remained stable in the other. This study showed that CU patients, especially those on omalizumab therapy, had difficulties in attending medical care and even in the maintenance of their existing therapies during the pandemic. Creating novel follow-up and treatment models as well as the increased use of teledermatology might be beneficial in the management of this life-disturbing condition.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Erdem Y,Polat Ekinci A,Altunay IK,Sivaz O,Inal S,Gokalp MO,Pehlivan G,Özkaya Edoi
10.1111/dth.14652subject
Has Abstractpub_date
2020-12-10 00:00:00pages
e14652eissn
1396-0296issn
1529-8019pub_type
杂志文章abstract::Maintaining the health of dermal fibroblast cells and controlling their growth and proliferation would directly affect the health of skin tissues. The present study encompassed three control and three experimental specimens, which were different in terms of the duration of exposure to electromagnetic field (EMF) and i...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13803
更新日期:2020-07-01 00:00:00
abstract::Hand-foot syndrome (HFS) is a specific cutaneous toxicity caused by a variety of antitumor drugs. The most common drugs include capecitabine, pegylated liposomal doxorubicin and fluorouracil (PLD), tyrosine kinase inhibitor. It is a dose-limiting cutaneous toxicity of these drugs. We reported an advanced lung adenocar...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13241
更新日期:2020-03-01 00:00:00
abstract::Reflectance confocal microscopy (RCM) enables the noninvasive in vivo imaging of the skin with a horizontal axis and a cellular-level resolution allowing the study of the skin from superficial layers to papillary dermis. It has arisen an important tool in the study of tumors and specially an important role in the char...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2012.01495.x
更新日期:2012-09-01 00:00:00
abstract::Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14094
更新日期:2020-11-01 00:00:00
abstract::Although there is still some controversy about the existence of psoriatic arthritis as a specific form of inflammatory arthritis associated with psoriasis, epidemiological, and clinical studies support the unique features of psoriatic arthritis. Because of lack of diagnostic or classification criteria, the disease has...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2004.04038.x
更新日期:2004-01-01 00:00:00
abstract::The isotretinoin registry has arrived. It has a lofty goal of preventing all isotretinoin pregnancies. How we got to this point and what the registry means to prescribers and patients have many dermatologists confused and concerned. Will it be burdensome, will it preclude the use in most offices of this most important...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2006.00080.x
更新日期:2006-07-01 00:00:00
abstract::Lichen planus is considered a T cell-mediated immunological disease. Even mast cells may contribute to the pathogenesis of the disease. Keratinocytes of the basal layer of the skin and/or the hair follicle may represent the "target/victim" of an immune aggression, determining the destruction of the hair follicle and t...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2010.01359.x
更新日期:2010-09-01 00:00:00
abstract::Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been an open debate on the impact of biological drugs used in the treatment of psoriasis. To define whether patients under treatment with biologics suffer from increased morbidity and mortality from COVID-19, compared to psoriatic patients ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14516
更新日期:2020-11-01 00:00:00
abstract:INTRODUCTION:Androgenetic Alopecia (AGA) with its precursor Miniaturization of Anagen phase (MA), and Telogen Effluvium (TE) represent non-scarring hair loss diseases which causes moderate to severe aesthetic and psychologic discomfort in affected people. Several therapeutic approaches have been tested through the late...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14799
更新日期:2021-01-24 00:00:00
abstract::A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12724
更新日期:2018-11-01 00:00:00
abstract::The condition of most patients with hyperhidrosis (HH) is known to worsen with increased temperature. However, most prior studies of oral glycopyrrolate (OGly) for the treatment of HH have assumed a stable treatment protocol, without taking into account seasonal variations in temperature. The main aim of this study is...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14249
更新日期:2020-11-01 00:00:00
abstract::Studies on microcystic adnexal carcinoma (MAC) survival rates have been limited. This effort examines the association of patient demographics, treatment modalities, and tumor stage with overall survival (OS) in patients with MAC of the head and neck. All cases of MAC with primary sites of the skin of the head and neck...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14559
更新日期:2020-11-18 00:00:00
abstract::Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14750
更新日期:2021-01-05 00:00:00
abstract::The highest efficacy of oral propranolol is for infantile hemangioma (IH) in the proliferative phase. Evaluation of the effectiveness of oral propranolol is less established when it is administered in late infancy following the proliferative phase. We aimed to assess the clinical outcomes of pediatric patients managed...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13331
更新日期:2020-05-01 00:00:00
abstract::Keloid often recur after treatment, and recent studies in keloid management favor the combination therapy of laser-assisted drug delivery over monotherapy. Unfortunately, the previous researches lack long-term follow-up. In this prospective study, 41 individuals with refractory keloids underwent eight treatment sessio...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14359
更新日期:2020-11-01 00:00:00
abstract::This is the first report of a case of porocarcinoma that was successfully treated with maxacalcitol and imiquimod. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.12830
更新日期:2019-03-01 00:00:00
abstract::Psychiatric symptoms in dermatology practice are increasingly being recognized. The use of psychiatric medications by dermatologist is dealt with caution and uncertainty in several psychodermatological conditions. Several skin conditions are associated with anxiety, depression, and obsessive-compulsive symptoms. Some ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13385
更新日期:2020-05-01 00:00:00
abstract::Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13022
更新日期:2019-09-01 00:00:00
abstract::Postherpetic neuralgia (PHN) is a debilitating disease characterized by continuous, intense pain following an outbreak of herpes zoster. The pain associated with PHN can severely affect a patient's quality of life, quality of sleep, and ability to participate in activities of daily living. The aim of this study was to...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13181
更新日期:2020-01-01 00:00:00
abstract::Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12083
更新日期:2014-05-01 00:00:00
abstract::Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12503
更新日期:2017-09-01 00:00:00
abstract::Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are medication-induced in most instances. While the clinical manifestations of SJS and TEN are well-defined, the optimal treatment for these disorders is not. Case reports have shown benefit with the use of a variet...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2011.01396.x
更新日期:2011-03-01 00:00:00
abstract::Moisturization is the pillar of daily skin care and has significant benefit in improving hydration, strengthening the skin barrier, and ameliorating inflammatory dermatoses. Bioactive ingredients such as endocannabinoids, bioactive lipids, growth factors, microbiome modulators, and antioxidant enzymes are increasingly...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13101
更新日期:2019-11-01 00:00:00
abstract::The World Health Organization has recently defined the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections as a pandemic. The infection, which may cause a potentially very severe respiratory disease, now called coronavirus disease 2019 (COVID-19), has airborne transmission via droplets while less a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13777
更新日期:2020-09-01 00:00:00
abstract::Scleredema is a deposition disorder which presents as diffuse, symmetric, non-pitting skin induration from dermal deposits of glycosaminoglycans ("mucins"). It classically affects the upper back and posterior neck, often causing skin tightness and decreased range of motion. In most patients the clinical course is chro...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12504
更新日期:2017-07-01 00:00:00
abstract::Fractional ablative carbon dioxide laser resurfacing is a frontline treatment for acne scars. It creates multiple microscopic treatment zones to accelerate the collagen formation and the healing process of reepithelialization, according the principle of fractional photothermolysis. At present, the fractional CO2 laser...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13084
更新日期:2019-11-01 00:00:00
abstract::There are many developmental abnormalities that may appear in the neonate and in infants when critical steps in embryogenesis fail. These steps are often not fatal but can lead to significant morbidity for those patients affected. A logical approach is needed in addressing both the diagnostic and therapeutic issues th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2005.05016.x
更新日期:2005-03-01 00:00:00
abstract::Photodynamic therapy (PDT), traditionally used in patients with nonmelanoma skin cancer, has been found to be effective for various inflammatory skin conditions. Daylight-activated PDT (DL-PDT), in which the sun serves as the light source, is substantially less painful than conventional PDT. This study aimed to determ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14329
更新日期:2020-11-01 00:00:00
abstract::The recent EAACI/GA2 LEN/EDF/WAO guidelines recommend omalizumab (anti-IgE) for the management of patients aged ≥12 years with chronic urticaria unresponsive to high-doses second-generation H1 -antihistamines (antiH1 ). However, there is little published information on the success of omalizumab for such a treatment in...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13489
更新日期:2020-07-01 00:00:00
abstract::As the first dermatological biological treatment, infliximab was first used in the treatment of psoriasis in 2001. Since that time many biological agents have come into use for dermatological diseases and developments in this area are still ongoing. The most important feature of biological treatments is that the treat...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12932
更新日期:2019-07-01 00:00:00