Efalizumab in the treatment of psoriasis: when comorbidity is an issue.

abstract：:The skin plays a critical role in the detection of internal malignances. Cutaneous signs of these disorders afford clinicians opportunities for early diagnosis and treatment. We aim to succinctly review the recognition, diagnosis, and treatment of selected cutaneous paraneoplastic diseases. Skin disorders that may be ...

journal_title：Dermatologic therapy

authors： Abreu Velez AM,Howard MS

更新日期：2010-11-01 00:00:00

abstract：:Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds...

journal_title：Dermatologic therapy

authors： Smolle J

更新日期：2003-01-01 00:00:00

abstract：:Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe chronic hand eczema in terms of drug survival and reasons for discontinuation. Patients ...

journal_title：Dermatologic therapy

authors： Politiek K,Christoffers WA,Coenraads PJ,Schuttelaar MA

更新日期：2016-09-01 00:00:00

abstract：:Alopecia areata (AA) is a common disease that results in nonscarring hair loss. Recently, tofacitinib (TOFA) has been a novel promising therapy for AA. The aim of this study is to determine the efficacy of oral TOFA treatment for alopecia areata (AA), and alopecia universalis (AU). Data of nine patients treated with o...

journal_title：Dermatologic therapy

authors： Akdogan N,Ersoy-Evans S,Doğan S,Atakan N

更新日期：2019-11-01 00:00:00

abstract：:Psoriasis is a chronic, systemic inflammatory disease that in the moderate to severe forms may benefit of biologics, namely TNF and IL-12/23 and IL-17 inhibitors. Loss of response, lack of response, or discontinuation due to adverse events represent a concrete therapeutic challenge for dermatologists that have to swit...

journal_title：Dermatologic therapy

authors： Damiani G,Conic RRZ,de Vita V,Costanzo A,Regazzini R,Pigatto PDM,Bragazzi NL,Pacifico A,Malagoli P

更新日期：2019-03-01 00:00:00

abstract：:Isotretinoin is an effective therapy for severe nodulocystic acne. Several experimental studies suggest that it may have an effect on vitamin D physiology. In the present study, the authors aimed to investigate the effect of isotretinoin treatment on the metabolism of vitamin D in acne patients. A prospective analysis...

journal_title：Dermatologic therapy

authors： Ertugrul DT,Karadag AS,Tutal E,Akin KO

更新日期：2011-03-01 00:00:00

abstract：:Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function. The study objective was to investigate short-term and long-term effects of two emollients on symptoms and skin barrier functions in xerotic eczema. Randomized, double-blind, study enrolling females/males, with b...

journal_title：Dermatologic therapy

authors： Simon D,Nobbe S,Nägeli M,Barysch M,Kunz M,Borelli S,Hasan-Ali O,Wildi E,Gasser UE

更新日期：2018-11-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF)-alpha inhibitors are licensed for patients with severe refractory psoriasis and psoriatic arthritis. However, TNF-alpha inhibitors have also been used off-label for various recalcitrant mucocutaneous diseases. This study aimed to evaluate the efficacy and safety of TNF-alpha inhibitor...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-05-01 00:00:00

abstract：:Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin and mucous membrane injury, which may cause acute and chronic dermatitis, secondary infection and aggravation of underlying skin diseases. This is a consensus of Chinese experts on protective measures and advice on hand-cleaning- ...

journal_title：Dermatologic therapy

authors： Yan Y,Chen H,Chen L,Cheng B,Diao P,Dong L,Gao X,Gu H,He L,Ji C,Jin H,Lai W,Lei T,Li L,Li L,Li R,Liu D,Liu W,Lu Q,Shi Y,Song J,Tao J,Wang B,Wang G,Wu Y,Xiang L,Xie J,Xu J,Yao Z,Zhang F,Zhang J,

更新日期：2020-07-01 00:00:00

abstract：:Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...

journal_title：Dermatologic therapy

authors： Barrett ME,Heller MM,Fullerton Stone H,Murase JE

更新日期：2013-07-01 00:00:00

abstract：:Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...

journal_title：Dermatologic therapy

authors： Liu M,Li X,Chen XY,Xue F,Zheng J

更新日期：2015-11-01 00:00:00

abstract：:Ischemic complications in cutaneous surgery can be devastating. Tissue ischemia can result from improper technique or closure design (i.e., increased tension), inadequate hemostasis, or infection, all of which result in decreased blood supply to the surgical site. Knowledge of patient characteristics that affect blood...

journal_title：Dermatologic therapy

authors： Delaney A,Diamantis S,Marks VJ

更新日期：2011-11-01 00:00:00

abstract：:The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...

journal_title：Dermatologic therapy

authors： Toth DP,Papp K,Gratton D

更新日期：2008-11-01 00:00:00

abstract：:Dermoscopy as a diagnostic tool is attaining impetus in inflammatory dermatoses with the cumulative description of characteristic findings in most dermatoses obviating at times the need of biopsy. In this retrospective observational study, 20 histopathology confirmed cases each of pityriasis rosea (PR), guttate psoria...

journal_title：Dermatologic therapy

authors： Jindal R,Chauhan P,Sethi S

更新日期：2020-12-05 00:00:00

abstract：:The World Health Organization has recently defined the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections as a pandemic. The infection, which may cause a potentially very severe respiratory disease, now called coronavirus disease 2019 (COVID-19), has airborne transmission via droplets while less a...

journal_title：Dermatologic therapy

authors： Elsaie ML,Nada HA

更新日期：2020-09-01 00:00:00

abstract：:Nodular elastosis with cysts and comedones also known as Favre-Racouchot syndrome frequently occurs on actinically damaged skin of middle-aged or elderly Caucasian subjects. The disease usually affects simmetrically the skin mainly around the orbits. Treatment in the past has not been entirely satisfactory. Treatment ...

journal_title：Dermatologic therapy

authors： Mavilia L,Campolmi P,Santoro G,Lotti T

更新日期：2010-01-01 00:00:00

abstract：:Dialkylcarbamoylchloride (DACC)-coated cotton acetate dressing works directly through hydrophobic interaction to reduce the number of bacteria without the risk of resistance. It is easy to use and therefore expected to improve patient's compliance. This study aimed to assess the clinical efficacy of DACC-coated cotton...

journal_title：Dermatologic therapy

authors： Dwiyana RF,Gondokaryono SP,Rahardja JI,Arline Diana I,Yogya Y,Gunawan H

更新日期：2019-09-01 00:00:00

abstract：:Acne is known as a chronic inflammatory skin disease with sever adverse effects on quality of life in the patients. The increasing resistance to antibiotics has decreased their effectiveness in treating acne. As viable microbial dietary supplements, probiotics provide health benefits through fighting pathogens and mai...

journal_title：Dermatologic therapy

authors： Goodarzi A,Mozafarpoor S,Bodaghabadi M,Mohamadi M

更新日期：2020-05-01 00:00:00

abstract：:Melasma is a hard-to-manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064-nm low-fluence Q-switched...

journal_title：Dermatologic therapy

authors： Abdel Hay R,Mohammed FN,Sayed KS,Abd El Fattah NA,Ibrahim S

更新日期：2020-07-01 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:Omalizumab is a monoclonal antibody, targeting Fc receptor of IgE, approved for the treatment of allergic asthma and chronic spontaneous urticaria. Its utility in atopic dermatitis appears controversial from data in literature since the molecule is well tolerated but it seems less effective than other medications used...

journal_title：Dermatologic therapy

authors： Iannelli M,Caminiti L,Vaccaro M,Marafioti I,Spinuzza A,Panasiti I,Barbalace A,Crisafulli G,Pajno GB

更新日期：2020-07-01 00:00:00

abstract：:There are many developmental abnormalities that may appear in the neonate and in infants when critical steps in embryogenesis fail. These steps are often not fatal but can lead to significant morbidity for those patients affected. A logical approach is needed in addressing both the diagnostic and therapeutic issues th...

journal_title：Dermatologic therapy

authors： Farvolden D,Sweeney SM,Wiss K

更新日期：2005-03-01 00:00:00

abstract：:Psoriasis of the scalp, face, intertriginous areas, genitals, hands, feet, and nails is often underdiagnosed, and disease management can be challenging. Despite the small surface area commonly affected by psoriasis in these locations, patients have disproportionate levels of physical impairment and emotional distress....

journal_title：Dermatologic therapy

authors： Merola JF,Qureshi A,Husni ME

更新日期：2018-05-01 00:00:00

abstract：:Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to...

journal_title：Dermatologic therapy

authors： Ertugrul G,Ertugrul S,Soylemez E

更新日期：2020-07-01 00:00:00

abstract：:Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...

journal_title：Dermatologic therapy

authors： Johansen MB,Jemec GBE,Fabricius S

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:Solid organ transplant recipients are at a significantly increased risk of developing skin cancer. Both systemic and topical retinoids are useful for chemosuppression of skin cancer in this patient population. These drugs can reduce both the present extent and the future development of premalignant and malignant skin ...

journal_title：Dermatologic therapy

authors： Neuhaus IM,Tope WD

更新日期：2005-01-01 00:00:00

abstract：:The purpose of the work was to assess changes in chemerin and irisin levels in women with diagnosed intrahepatic cholestasis of pregnant women treated with ursodeoxycholic acid. The study group consisted of 50 patients with diagnosed and confirmed intrahepatic cholestasis of pregnant women at 24-25 weeks of pregnancy ...

journal_title：Dermatologic therapy

authors： Dąbrowski K,Kierach R,Grabarek BO,Boroń D,Kukla M

更新日期：2020-03-01 00:00:00

abstract：:Lyophilized-growth factors (L-GFs), is a new platelet rich plasma (PRP) preparation that is standardized in growth factors concentrations. The aim of this study was to compare the therapeutic efficacy of ablative fractional CO2 laser in combination with L-GFs vs PRP in post-acne scars. This study was conducted on 45 p...

journal_title：Dermatologic therapy

authors： Neinaa YME,Al-Khayat LA,Suliman GAM,Ameen TE

更新日期：2020-11-01 00:00:00

abstract：:Pigmented lesions represent an enormous range of conditions, from benign to malignant tumors, and from infectious to post-inflammatory. Pigmented lesions are much less easily diagnosed on anogenital skin, and clinicians should have a low threshold for biopsy confirmation of diseases not classic in appearance. ...

journal_title：Dermatologic therapy

authors： Edwards L

更新日期：2010-09-01 00:00:00