Investigation of hearing and outer hair cell function of the cochlea in patients with vitiligo.

Abstract:

:Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to determine which disease-related parameters trigger damage to cochlear melanocytes in vitiligo patients and the effect of vitiligo on the outer hair cells and hearing. Thirty-one vitiligo patients and 40 sex- and age-matched healthy volunteers were evaluated. The conventional pure tone audiometry (C-PTA) test and the distortion product otoacoustic emission (DPOAE) test were performed. There was no significant difference between vitiligo patients and controls in C-PTA test results, but the DPOAE test results were abnormal in vitiligo patients. The duration of the disease was significantly related to hypoacusis. As the duration of the disease increases, cochlear dysfunction may increase. Especially in patients with longer disease duration, otoacoustic emission tests should be performed in addition to conventional audiometry tests for early detection of damage to the outer hair cells.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Ertugrul G,Ertugrul S,Soylemez E

doi

10.1111/dth.13724

subject

Has Abstract

pub_date

2020-07-01 00:00:00

pages

e13724

issue

4

eissn

1396-0296

issn

1529-8019

journal_volume

33

pub_type

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