Off-label use of TNF-alpha inhibitors in a dermatological university department: retrospective evaluation of 118 patients.

abstract：:During the past 20 years, tremendous progress has been made in our understanding of the molecular basis of many genetic skin conditions. The translation of these laboratory findings into effective therapies for affected individuals has been slow, however, in large part due to the risk of carcinogenesis from random vir...

journal_title：Dermatologic therapy

authors： Lai-Cheong JE,Elias PM,Paller AS

更新日期：2013-01-01 00:00:00

abstract：:COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and other potential drugs have been studied for COVID19 treatment. We reviewed t...

journal_title：Dermatologic therapy

authors： Türsen Ü,Türsen B,Lotti T

更新日期：2020-07-01 00:00:00

abstract：:Cutaneous necrotizing vasculitis is a heterogeneous group of disorders characterized clinically by palpable purpura, and histologically by a segmental angiocentric inflammatory condition with fibrinoid necrosis of the vessel wall, endothelial swelling, and nuclear dust of the post capillary venules. Often, the skin se...

journal_title：Dermatologic therapy

authors： Tsampau D,Buggiani G,Hercogova J,Lotti T

更新日期：2012-07-01 00:00:00

abstract：:Spontaneous remission occurs in less than 10% of patients suffering from alopecia areata (AA) totalis for more than 2 years. The efficacy of PUVA therapy is controversial due to recurrence of hair loss after cessation. We report two cases presenting with AA totalis and AA universalis. After hair regrowth, relapse of h...

journal_title：Dermatologic therapy

authors： Lux-Battistelli C

更新日期：2015-07-01 00:00:00

abstract：:Many traditional Chinese medicine compositions can moisturize the skin and utilize in cosmetics. Using a combination of Chinese Medicine Materials and guided by Traditional Chinese Medicine principles, this study selected Echinacea purpurea to protect the skin barrier, Dendrobium nobile to clear heat and promote fluid...

journal_title：Dermatologic therapy

authors： Meng H,Li J,Dong Y,He Y,Ren H,Liu Y,Qu Z,Zhang W,Zhang L,Bao T,Yi F

更新日期：2020-11-01 00:00:00

abstract：:Zoonoses are infectious diseases that can be transmitted from animals to humans. Transmission occurs directly or through vectors such as ticks, mosquitoes, or flies. The causative agents include bacteria, parasites, viruses, and fungi. Domestic pets and livestock, as well as wild animals, can be the source of disease....

journal_title：Dermatologic therapy

authors： Wilson M,Lountzis N,Ferringer T

更新日期：2009-07-01 00:00:00

abstract：:Hydrogels based on hyaluronic acid are used to restore volume, hydration, and skin tone, as well as to correct scars, asymmetries or defects of the soft tissue. Hyaluronic acid is often chemically crosslinked with different crosslinking agents in order to improve its mechanical and biological properties. Here we focus...

journal_title：Dermatologic therapy

authors： Zerbinati N,Esposito C,Cipolla G,Calligaro A,Monticelli D,Martina V,Golubovic M,Binic I,Sigova J,Gallo AL,D'Este E,Jafferany M,Pratosoni M,Tirant M,Van Thuong N,Sangalli F,Rauso R,Lotti T

更新日期：2020-07-01 00:00:00

abstract：:Both in the topical and systemic treatment of psoriasis, retinoids are mainstays. In this chapter the history and modes of actions of retinoids are presented. Tazarotene and acitretin are the only retinoids that are available in both topical and systemic formulations. A more extensive description of their pharmacology...

journal_title：Dermatologic therapy

authors： van de Kerkhof PC

更新日期：2006-09-01 00:00:00

abstract：:Androgenetic alopecia also known as pattern alopecia, is a disorder characterized by the gradual onset of the conversion of terminal hairs into vellus hairs. Dexpanthenol has an anti-oxidative and anti-inflammatory effect and a cellular repair capability. We present nine male cases who had marked improvement after rec...

journal_title：Dermatologic therapy

authors： Kutlu Ö

更新日期：2020-05-01 00:00:00

abstract：:Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...

journal_title：Dermatologic therapy

authors： Taraz M,Niknam S,Ehsani AH

更新日期：2017-05-01 00:00:00

abstract：:Reflectance confocal microscopy (RCM) enables the noninvasive in vivo imaging of the skin with a horizontal axis and a cellular-level resolution allowing the study of the skin from superficial layers to papillary dermis. It has arisen an important tool in the study of tumors and specially an important role in the char...

journal_title：Dermatologic therapy

authors： Carrera C,Puig S,Malvehy J

更新日期：2012-09-01 00:00:00

abstract：:Desquamative inflammatory vaginitis (DIV) is not a diagnosis in itself, and may be the presentation of a range of blistering disorders including pemphigus vulgaris, lichen planus and mucous membrane pemphigoid. The existence of an idiopathic subset of DIV remains controversial and is discussed in the present article. ...

journal_title：Dermatologic therapy

authors： Murphy R

更新日期：2004-01-01 00:00:00

abstract：:Pemphigus is a group of autoimmune diseases characterized by the formation of erosions and/or flaccid bullae of the skin and/or mucosae. The definition "drug-induced pemphigus" has been coined to indicate cases of pemphigus with clinical, histological and immunopathologic features similar to those of the idiopathic di...

journal_title：Dermatologic therapy

authors： Palleria C,Bennardo L,Dastoli S,Iannone LF,Silvestri M,Manti A,Nisticò SP,Russo E,De Sarro G

更新日期：2019-01-01 00:00:00

abstract：:Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...

journal_title：Dermatologic therapy

authors： Liu M,Li X,Chen XY,Xue F,Zheng J

更新日期：2015-11-01 00:00:00

abstract：:Treatment of warts is considered as a big challenge for patients as well as doctors. Immunotherapy represents a promising and successful method of warts treatment. A great attention has been paid for various types of immunotherapeutic agents. One of the immunotherapeutic approaches is intralesional immunotherapy that ...

journal_title：Dermatologic therapy

authors： Amer A,Nassar A,Gamal D,Marei A

更新日期：2020-12-12 00:00:00

abstract：:Behçet's disease (BD) is an autoimmune disease that affects many organs. We aimed to investigate the relationship between BD and these pregnancy-associated plasma protein A (PAPP-A), neopterin, and high sensitive C-reactive protein (hsCRP) parameters. The study included 57 BD patients and 54 healthy controls. After ev...

journal_title：Dermatologic therapy

authors： Akyurek F,Tuncez Akyurek F

更新日期：2020-07-01 00:00:00

abstract：:Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...

journal_title：Dermatologic therapy

authors： Bar-Ilan E,Koren A,Shehadeh W,Mashiah J,Sprecher E,Artzi O

更新日期：2020-01-01 00:00:00

abstract：:Photodynamic therapy (PDT), traditionally used in patients with nonmelanoma skin cancer, has been found to be effective for various inflammatory skin conditions. Daylight-activated PDT (DL-PDT), in which the sun serves as the light source, is substantially less painful than conventional PDT. This study aimed to determ...

journal_title：Dermatologic therapy

authors： Kremer N,Sherman S,Lapidoth M,Enk CD,Leshem YA,Mimouni T,Dudkiewicz D,Hodak E,Levi A

更新日期：2020-11-01 00:00:00

abstract：:Pruritus is associated with various skin diseases, dry skin, and with it an impaired skin barrier function. The study objective was to investigate short-term and long-term effects of two emollients on symptoms and skin barrier functions in xerotic eczema. Randomized, double-blind, study enrolling females/males, with b...

journal_title：Dermatologic therapy

authors： Simon D,Nobbe S,Nägeli M,Barysch M,Kunz M,Borelli S,Hasan-Ali O,Wildi E,Gasser UE

更新日期：2018-11-01 00:00:00

abstract：:Tattoos have long become a part of human civilization. However, as the number of people who get tattoos increases, so is the number of people who wish to have their tattoos removed. Compared to other methods, laser-based devices are associated with the best efficacy and least side effects in tattoo removal. Lack of un...

journal_title：Dermatologic therapy

authors： Kurniadi I,Tabri F,Madjid A,Anwar AI,Widita W

更新日期：2020-10-17 00:00:00

abstract：:Non-peristomal postoperative pyoderma gangrenosum (PPG) is a rare subtype of pyoderma gangrenosum that occurs in the early postoperative period at surgical incisions, most commonly after breast surgery. Early diagnosis and treatment is essential to prevent severe scaring. TNF-alpha inhibitor infliximab was reported to...

journal_title：Dermatologic therapy

authors： Ariane M,Bouaziz JD,de Masson A,Jachiet M,Bagot M,Lepelletier C

更新日期：2019-01-01 00:00:00

abstract：:Nucleosomes are typically located intracellularly, and extracellular levels of nucleosomes indicated the degree of cell death. We postulated aberrant nucleosomes expression in dermatomyositis (DM) and polymyositis (PM). To assess the aberrant expression of circulating nucleosomes in DM and polymyositis. 76 consecutive...

journal_title：Dermatologic therapy

authors： Zhong D,Wu C,Bai J,Zhao J,Xu D,Li M,Wang Q,Wang F,Zeng X

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To explore the inhibition of the proliferation of vulvar squamous cell carcinoma (VSCC) by astragaloside IV. METHODS:MTT examined the cell proliferation of VSCC. Flow cytometry analyzed cell cycle and apoptosis. Western blot assay detected the expression of some relevant proteins. RESULTS:AS-IV reduced the ...

journal_title：Dermatologic therapy

authors： Zhao Y,Wang L,Wang Y,Dong S,Yang S,Guan Y,Wu X

更新日期：2019-07-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...

journal_title：Dermatologic therapy

authors： Asilian A,Kazemipour S,Mokhtari F,Iraji F,Shahmoradi Z,Mohaghegh F,Mozafarpoor S,Talakoub M

更新日期：2021-01-05 00:00:00

abstract：:Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR)...

journal_title：Dermatologic therapy

authors： Fawzy MM,Nofal A,Alakad R

更新日期：2020-11-01 00:00:00

abstract：:Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds...

journal_title：Dermatologic therapy

authors： Smolle J

更新日期：2003-01-01 00:00:00

abstract：:A change of pricing policy in Spain have made both doses of ustekinumab (UST), 45 and 90 mg, recently available at the same price. Our primary objective was to evaluate effectiveness of UST 90 mg at 52 and 104 weeks in psoriasis patients in clinical practice; secondary objectives were to study the reasons for using th...

journal_title：Dermatologic therapy

authors： Llamas-Velasco M,Baniandrés O,Rivera R,Reymundo Jimenez A,Hospital M,García Zamora E,González-Cantero Á,Andrés Lencina JJ,Daudén E,de la Cueva P

更新日期：2020-07-01 00:00:00

abstract：:Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2014-07-01 00:00:00

abstract：:Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to...

journal_title：Dermatologic therapy

authors： Ertugrul G,Ertugrul S,Soylemez E

更新日期：2020-07-01 00:00:00