Abstract:
:Both in the topical and systemic treatment of psoriasis, retinoids are mainstays. In this chapter the history and modes of actions of retinoids are presented. Tazarotene and acitretin are the only retinoids that are available in both topical and systemic formulations. A more extensive description of their pharmacology, modes of action, indications and contraindications, clinical results, and treatment strategies will be presented. Finally, retinoid X receptor ligands and retinoic acid metabolism blocking agents will be introduced as potential future retinoid mimetics in psoriasis.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
van de Kerkhof PCdoi
10.1111/j.1529-8019.2006.00082.xsubject
Has Abstractpub_date
2006-09-01 00:00:00pages
252-63issue
5eissn
1396-0296issn
1529-8019pii
DTH082journal_volume
19pub_type
杂志文章,评审abstract::Soft-tissue augmentation with hyaluronic acid and calcium hydroxyl apatite are among the most widely used minimally invasive cosmetic treatments for the correction of contour deficiencies and wrinkles of the face without the risk, recovery time, and expense of a major surgery. Training and experience in the art and sc...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01380.x
更新日期:2011-01-01 00:00:00
abstract::The world entered the year 2020 with reports of the emergence of a new viral illness in Wuhan city, Hubei province, China. In January 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified to be the causative novel coronavirus for the cluster of patients suffering from pneumonia in China. Th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13677
更新日期:2020-07-01 00:00:00
abstract::The objective of our study was to describe the effectiveness and safety of oral dutasteride (OD) for male androgenetic alopecia in real clinical practice. A retrospective, monocentric, and descriptive study was designed. Male patients with androgenetic alopecia that had received OD for at least 12 months were included...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13182
更新日期:2020-01-01 00:00:00
abstract::Pustulosis palmoplantaris (PPP; synonyms: pustulosis palmaris et plantaris, palmoplantar amicrobic pustulosis) is a common chronic, relapsing, pustular eruption affecting the palms and soles. The authors report the successful treatment of six therapy-experienced patients with histologically confirmed PPP with oral itr...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2008.01219.x
更新日期:2009-01-01 00:00:00
abstract::Although acne is not an infectious disease, oral antibiotics have remained a mainstay of treatment over the last 40 years. The anti-inflammatory properties of oral antibiotics, particularly the tetracyclines, are efficacious in treating inflammatory acne lesions. Common prescribing practices in Dermatology exert signi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12370
更新日期:2016-09-01 00:00:00
abstract::Protozoan infections can have a variety of different cutaneous manifestations in addition to systemic signs and symptoms of disease. Recognition and diagnosis can be difficult, as additional laboratory tests, in addition to biopsies, may be required. Treatment options for different protozoa vary and resolution of dise...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2004.04054.x
更新日期:2004-01-01 00:00:00
abstract::Palmoplantar pustulosis is a chronic inflammatory disease which characterized by a eruption of sterile pustules on the palms and soles. Apremilast is an oral phosphodiesterase-4 inhibitor which is approved for the treatment of chronic plaque psoriasis and psoriatic arthritis. However, no clinical trial has been perfor...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13230
更新日期:2020-03-01 00:00:00
abstract::Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12503
更新日期:2017-09-01 00:00:00
abstract::Tinea are superficial fungal infections caused by dermatophytes. Luliconazole exhibits highest antifungal activity against Trichophyton spp. which are major causative agents of dermatophytosis. However, luliconazole suffers from drawbacks such as less skin retention, low aqueous solubility and poor skin penetration. T...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13959
更新日期:2020-11-01 00:00:00
abstract::Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious and a particularly popular problem in all around the World and also in all departments of every hospital. In order to protect the well-being of health care providers while providing a sufficient wor...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13438
更新日期:2020-07-01 00:00:00
abstract::Growth factors play an important role in reversing the effects of skin aging mediated by chronological and environmental factors. Excessive oxidation of intra- and extracellular components result in breakdown of collagen and elastin network in the dermis and produce the effect of facial aging. Topical application of h...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2007.00149.x
更新日期:2007-09-01 00:00:00
abstract::COVID-19 disease is a highly contagious and particularly popular problem in all countries. A variety of repurposed drugs and investigational drugs such as remdesivir, chloroquine, hydroxychloroquine, ritonavir, lopinavir, interferon-beta, and other potential drugs have been studied for COVID19 treatment. We reviewed t...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13476
更新日期:2020-07-01 00:00:00
abstract::Plantar warts can cause pain near the toes and the sole of the foot and may result in referral for treatment. This study was aimed at comparing 40% trichloroacetic acid (TCA) and cryotherapy (Cryo) for the treatment of plantar warts. This single-blind, randomized clinical trial was performed on 60 subjects presenting ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13559
更新日期:2020-07-01 00:00:00
abstract::Malignant melanoma is considered to be an immunogenic tumor, which is expected to change its behaviour in the field of immunosuppression. Although the incidence of melanoma in organ transplant recipients is increased to a smaller degree than in non-melanoma skin cancer, its potential morbidity and mortality has to be ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12276
更新日期:2016-01-01 00:00:00
abstract::Vitiligo is quite a common hypopigmentary disorder, which may affect both children and adults with important psychological effects due to the well-known leopard skin-like appearance. The authors summarize in the present study the published evidence on vitiligo with particular interest on the controversial aspects of t...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12745
更新日期:2019-01-01 00:00:00
abstract::Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14750
更新日期:2021-01-05 00:00:00
abstract::Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14094
更新日期:2020-11-01 00:00:00
abstract::Keratoacanthoma centrifugum marginatum (KCM) is a rare variant of keratoacanthoma. This condition is difficult to diagnose because of its large size and expansive nature and may be diagnosed as a malignant tumor. There are various treatments such as surgery and oral retinoids; however, limited studies have verified th...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13291
更新日期:2020-05-01 00:00:00
abstract::Clinical research plays a very important role in the development of drugs and devices, including those for wound healing. The process of initiating a clinical trial can be rather daunting, particularly with the ever-increasing regulatory hurdles. Many clinicians are generally either not trained or have limited knowled...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2006.00095.x
更新日期:2006-11-01 00:00:00
abstract::Psoriasis is associated with an increased risk of atherosclerosis. The objective of this study is evaluate the relationship between carotid intima-media thickness (CIMT) serum and cystatin-C, fetuin-A levels in determining the increased risk of subclinical atherosclerosis in psoriasis patients. In this study, age and ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13898
更新日期:2020-11-01 00:00:00
abstract::Maintaining the health of dermal fibroblast cells and controlling their growth and proliferation would directly affect the health of skin tissues. The present study encompassed three control and three experimental specimens, which were different in terms of the duration of exposure to electromagnetic field (EMF) and i...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13803
更新日期:2020-07-01 00:00:00
abstract::Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO(2) laser fluences, by modulating the secret...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2009.01265.x
更新日期:2009-11-01 00:00:00
abstract::The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00224.x
更新日期:2008-09-01 00:00:00
abstract::Hand dermatitis is a common skin condition that often has a chronic and/or relapsing clinical course. Several clinical forms of hand dermatitis have been described, including contact (i.e., allergic and irritant), hyperkeratotic (i.e., psoriasiform or tylotic), frictional, nummular, atopic, pompholyx (i.e., dyshidrosi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2004.04025.x
更新日期:2004-01-01 00:00:00
abstract::The present authors report the case of a 9-year-old boy affected by psoriasis, juvenile psoriatic arthritis, enthesitis, and celiac disease. The signs and symptoms of the different comorbidities appeared at different times in the clinical history, complicating the overall diagnostic and therapeutic procedures. Coopera...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01301.x
更新日期:2010-03-01 00:00:00
abstract::Psoriasis is an inflammatory, immune-mediated cutaneous disorder that has recently been recognized as systemic disease that is associated with multiple comorbidities such as depression, obesity, and the metabolic syndrome. The metabolic syndrome is the constellation of abdominal obesity, dyslipidemia, hypertension and...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01307.x
更新日期:2010-03-01 00:00:00
abstract::The oral mucosa is a common site for collateral damage of cancer therapies, including radiation, cytotoxic medication, and newer targeted therapies. Ulcerative oral mucositis is typically painful and affects oral functions including speech, and oral intake of food and medications, thus impacting the quality of life. D...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2011.01434.x
更新日期:2011-07-01 00:00:00
abstract::Adult colloid milium is a rare cutaneous deposition disorder that frequently involves areas of chronic sun exposure. The most common clinical presentation exhibits multiple, firm, and amber-colored papules that cluster to form large plaques. Histologically, there are masses of amorphous, eosinophilic material expandin...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12056
更新日期:2014-03-01 00:00:00
abstract::Up until now, real-life experiences on the efficacy of risankizumab in patients who had previously failed anti-IL17, anti-IL12/23 or anti-IL23 inhibitor are not reported. We carried out a single-center, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14144
更新日期:2020-11-01 00:00:00
abstract:INTRODUCTION:Androgenetic Alopecia (AGA) with its precursor Miniaturization of Anagen phase (MA), and Telogen Effluvium (TE) represent non-scarring hair loss diseases which causes moderate to severe aesthetic and psychologic discomfort in affected people. Several therapeutic approaches have been tested through the late...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14799
更新日期:2021-01-24 00:00:00