Efficacy and safety of risankizumab in psoriasis patients who failed anti-IL-17, anti-12/23 and/or anti IL-23: Preliminary data of a real-life 16-week retrospective study.

abstract：:The development of effective and well-tolerated biologic therapies has advanced the management of psoriasis by enabling clinicians to treat underlying disease mechanisms. Biologics approved for the treatment of moderate-to-severe psoriasis include three tumor necrosis factor alpha inhibitors and an interleukin-12/inte...

journal_title：Dermatologic therapy

authors： Gaspari AA,Tyring S

更新日期：2015-07-01 00:00:00

abstract：:It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages o...

journal_title：Dermatologic therapy

authors： Sambrano B,Gordon R,Mays R,Lapolla W,Scheinfeld N

更新日期：2012-01-01 00:00:00

abstract：:Psoriasis is associated with an increased risk of atherosclerosis. The objective of this study is evaluate the relationship between carotid intima-media thickness (CIMT) serum and cystatin-C, fetuin-A levels in determining the increased risk of subclinical atherosclerosis in psoriasis patients. In this study, age and ...

journal_title：Dermatologic therapy

authors： Demirbaş A,Kurtipek GS,Tunçez A,Akyürek F,Demirbaş GU

更新日期：2020-11-01 00:00:00

abstract：:Nail involvement can place a significant burden on patients as a result of functional damage and psychosocial problems, leading to major repercussions on the quality of life. There is strong evidence that nail psoriasis can often be difficult to treat. We report a 69-year-old man with severe onychodystrophy, onycholys...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Chimenti MS,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of pati...

journal_title：Dermatologic therapy

authors： Del Boz J,Millán-Cayetano JF,García-Montero P,García-Harana C,Rivas-Ruiz F,de Troya-Martín M

更新日期：2018-07-01 00:00:00

abstract：:Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO(2) laser treatment shows peculiar effects in the skin, mainly due to its ability of modula...

journal_title：Dermatologic therapy

authors： Buggiani G,Tsampau D,Krysenka A,De Giorgi V,Hercogová J

更新日期：2012-11-01 00:00:00

abstract：:Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglan...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2016-11-01 00:00:00

abstract：:Desquamative inflammatory vaginitis (DIV) is not a diagnosis in itself, and may be the presentation of a range of blistering disorders including pemphigus vulgaris, lichen planus and mucous membrane pemphigoid. The existence of an idiopathic subset of DIV remains controversial and is discussed in the present article. ...

journal_title：Dermatologic therapy

authors： Murphy R

更新日期：2004-01-01 00:00:00

abstract：:Despite the high prevalence of pulmonary tuberculosis worldwide, extrapulmonary tuberculosis especially cutaneous and osteoarticular tuberculosis occurs rarely, both of which are often difficult to be recognized since their symptoms mimic those of many other cutaneous and osteoarticular diseases. Here, we present a ra...

journal_title：Dermatologic therapy

authors： Li Z,Wang S,Chen X,Ming X,Peng L,Li W

更新日期：2018-07-01 00:00:00

abstract：:A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...

journal_title：Dermatologic therapy

authors： Hussain K,Gkini MA,Taylor R,Shinhmar S,Bewley A

更新日期：2018-11-01 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:The safety of methotrexate in psoriasis patients with metabolic syndrome could be argued because of increased risk of liver toxicity. The aim of the study was to investigate the safety of methotrexate compared with secukinumab in psoriasis patients with metabolic syndrome. A controlled, open trial in psoriasis patient...

journal_title：Dermatologic therapy

authors： Gisondi P,Bellinato F,Bruni M,De Angelis G,Girolomoni G

更新日期：2020-11-01 00:00:00

abstract：INTRODUCTION:Androgenetic Alopecia (AGA) with its precursor Miniaturization of Anagen phase (MA), and Telogen Effluvium (TE) represent non-scarring hair loss diseases which causes moderate to severe aesthetic and psychologic discomfort in affected people. Several therapeutic approaches have been tested through the late...

journal_title：Dermatologic therapy

authors： Piccolo D,Crisman G,Conforti C,Buzzi M,Genovesi C,Marchi D,Mazzaracchio D,Goldust M

更新日期：2021-01-24 00:00:00

abstract：:During the past 20 years, tremendous progress has been made in our understanding of the molecular basis of many genetic skin conditions. The translation of these laboratory findings into effective therapies for affected individuals has been slow, however, in large part due to the risk of carcinogenesis from random vir...

journal_title：Dermatologic therapy

authors： Lai-Cheong JE,Elias PM,Paller AS

更新日期：2013-01-01 00:00:00

abstract：:Prayer marks are asymptomatic callosities resulting from repeated, extended pressure, and friction exerted on bony prominences when praying on hard ground. A 41-year-old woman with ulcerative colitis treated with infliximab was referred to our clinic due to skin changes on her feet that were suspected to be drug erupt...

journal_title：Dermatologic therapy

authors： Fosse N,Rast AC,Kammermann A,Sonderegger J,Navarini A,Goldust M,Brandt O,Mueller SM

更新日期：2020-01-01 00:00:00

abstract：:Keloid often recur after treatment, and recent studies in keloid management favor the combination therapy of laser-assisted drug delivery over monotherapy. Unfortunately, the previous researches lack long-term follow-up. In this prospective study, 41 individuals with refractory keloids underwent eight treatment sessio...

journal_title：Dermatologic therapy

authors： Wang J,Wu J,Xu M,Gao Q,Chen B,Wang F,Song H

更新日期：2020-11-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF)-alpha inhibitors are licensed for patients with severe refractory psoriasis and psoriatic arthritis. However, TNF-alpha inhibitors have also been used off-label for various recalcitrant mucocutaneous diseases. This study aimed to evaluate the efficacy and safety of TNF-alpha inhibitor...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-05-01 00:00:00

abstract：:Isotretinoin is a safe and useful medication for acne management. Adverse effects are mostly related to cutaneous and mucous membranes. We present a case of a 24-year-old female patient who was on treatment with isotretinoin for acne vulgaris Grade 4. After 6 months of treatment, the patient presented with localized p...

journal_title：Dermatologic therapy

authors： Gupta M,Lotti T,Goldust M

更新日期：2020-05-01 00:00:00

abstract：:Vitiligo is quite a common hypopigmentary disorder, which may affect both children and adults with important psychological effects due to the well-known leopard skin-like appearance. The authors summarize in the present study the published evidence on vitiligo with particular interest on the controversial aspects of t...

journal_title：Dermatologic therapy

authors： Lotti T,Gianfaldoni S,Valle Y,Rovesti M,Feliciano C,Satolli F

更新日期：2019-01-01 00:00:00

abstract：:Psoriasis is a chronic, systemic inflammatory disease that in the moderate to severe forms may benefit of biologics, namely TNF and IL-12/23 and IL-17 inhibitors. Loss of response, lack of response, or discontinuation due to adverse events represent a concrete therapeutic challenge for dermatologists that have to swit...

journal_title：Dermatologic therapy

authors： Damiani G,Conic RRZ,de Vita V,Costanzo A,Regazzini R,Pigatto PDM,Bragazzi NL,Pacifico A,Malagoli P

更新日期：2019-03-01 00:00:00

abstract：:Onychomycosis is an important medical disorder affecting both health and quality of life of patients. This study was done to compare the efficacy of CO2 laser in combination with topical tioconazole versus CO2 laser only versus topical tioconazole alone in onychomycosis. A total of 120 patients with onychomycosis were...

journal_title：Dermatologic therapy

authors： Zaki AM,Abdo HM,Ebadah MA,Ibrahim SM

更新日期：2020-01-01 00:00:00

abstract：:This article presents a short summary of our current knowledge of cicatricial alopecia disease pathogenesis and the hypothetical disease mechanisms that may be involved in scarring alopecia development. Several forms of scarring alopecia likely involve targeted cytotoxic action against hair follicle cells mediated by ...

journal_title：Dermatologic therapy

authors： McElwee KJ

更新日期：2008-07-01 00:00:00

abstract：:Past studies have reported associations between psoriasis, metabolic syndrome, and atherosclerotic cardiovascular disease. According to studies, N-terminal pro B-type natriuretic peptide (NT-proBNP) is a useful screening test for cardiac disease. We examined the serum NT-proBNP level in patients with psoriasis and com...

journal_title：Dermatologic therapy

authors： Shahidi-Dadras M,Niknezhad N,Niknejad N,Zargari O

更新日期：2019-05-01 00:00:00

abstract：:Treatment of pustular psoriasis in pregnancy is often difficult to manage and is hampered by limited treatment options. We describe herein a patient who was treated with secukinumab after an unsatisfying response to oral steroids and cyclosporin. ...

journal_title：Dermatologic therapy

authors： Chhabra G,Chanana C,Verma P,Saxena A

更新日期：2019-09-01 00:00:00

abstract：:Ischemic complications in cutaneous surgery can be devastating. Tissue ischemia can result from improper technique or closure design (i.e., increased tension), inadequate hemostasis, or infection, all of which result in decreased blood supply to the surgical site. Knowledge of patient characteristics that affect blood...

journal_title：Dermatologic therapy

authors： Delaney A,Diamantis S,Marks VJ

更新日期：2011-11-01 00:00:00

abstract：:Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...

journal_title：Dermatologic therapy

authors： Conti A,Piaserico S,Gisondi P,Odorici G,Galdo G,Lasagni C,Pellacani G

更新日期：2017-09-01 00:00:00

abstract：:Psoriasis impacts the quality of life (QoL) by disrupting overall health and social life. Thus, the use of a QoL evaluation item is crucial in assessing a therapeutic regimen. Also, faster improvements in QoL lead to better patient compliance, but very few studies compare psoriasis traditional and biologic therapies t...

journal_title：Dermatologic therapy

authors： Pistone G,Gurreri R,Tilotta G,Caruso P,Curiale S,Bongiorno MR

更新日期：2019-09-01 00:00:00

abstract：:Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...

journal_title：Dermatologic therapy

authors： Agha R,Mirowski GW

更新日期：2010-05-01 00:00:00

abstract：:Photodynamic therapy (PDT), traditionally used in patients with nonmelanoma skin cancer, has been found to be effective for various inflammatory skin conditions. Daylight-activated PDT (DL-PDT), in which the sun serves as the light source, is substantially less painful than conventional PDT. This study aimed to determ...

journal_title：Dermatologic therapy

authors： Kremer N,Sherman S,Lapidoth M,Enk CD,Leshem YA,Mimouni T,Dudkiewicz D,Hodak E,Levi A

更新日期：2020-11-01 00:00:00

abstract：:Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...

journal_title：Dermatologic therapy

authors： Zackheim HS

更新日期：2003-01-01 00:00:00