Abstract:
:Palmoplantar pustulosis is a chronic inflammatory disease which characterized by a eruption of sterile pustules on the palms and soles. Apremilast is an oral phosphodiesterase-4 inhibitor which is approved for the treatment of chronic plaque psoriasis and psoriatic arthritis. However, no clinical trial has been performed to confirm the efficacy of apremilast for palmoplantar pustulosis yet. Moreover, there are very few cases of this disease treated with apremilast. Herein, we describe a case of a refractory palmoplantar pustulosis succesfully treated with apremilast.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Carrascosa de Lome R,Conde Montero E,de la Cueva Dobao Pdoi
10.1111/dth.13230subject
Has Abstractpub_date
2020-03-01 00:00:00pages
e13230issue
2eissn
1396-0296issn
1529-8019journal_volume
33pub_type
信件abstract::Pustulosis palmoplantaris (PPP; synonyms: pustulosis palmaris et plantaris, palmoplantar amicrobic pustulosis) is a common chronic, relapsing, pustular eruption affecting the palms and soles. The authors report the successful treatment of six therapy-experienced patients with histologically confirmed PPP with oral itr...
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