Abstract:
:Treatment of warts is considered as a big challenge for patients as well as doctors. Immunotherapy represents a promising and successful method of warts treatment. A great attention has been paid for various types of immunotherapeutic agents. One of the immunotherapeutic approaches is intralesional immunotherapy that showed a successful result in treatment of warts. Complete resolution of warts was achieved in many of studied patients, while some of them showed partial response and only few patients showed no response. Our study was based on the previous observations and reports of regression of several types of warts after administration of candida antigen and other new immunotherapeutic antigens. Candida antigen group showed complete clearance in 16 patients (69.6%), partial response in seven patients (30.4%). In VZV vaccine group, complete clearance was observed in 15 patients (65.2%), partial response in eight patients (34.8%). These results showed that the therapeutic response in two groups had a close statistical result and more chances must be given to VZV vaccine specially after its promising and successful results. In conclusion, we presented a novel approach for the treatment of recalcitrant wart using intralesional immunotherapy with Candida antigen and VZV vaccine. VZV vaccine seems to be promising, safe and effective remedy for any type warts mainly plantar warts.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Amer A,Nassar A,Gamal D,Marei Adoi
10.1111/dth.14667subject
Has Abstractpub_date
2020-12-12 00:00:00pages
e14667eissn
1396-0296issn
1529-8019pub_type
杂志文章abstract::Smooth, lustrous nails are a sign of health and beauty in our society and fuel the US$6-billion nail salon industry in the United States. Although many women can use nail cosmetics without adverse consequences, when problems occur it is important to recognize the causes and treat the problem condition. The cornerstone...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2007.00111.x
更新日期:2007-01-01 00:00:00
abstract::Filiform warts are commonly treated with surgical removal or cryotherapy, yet such treatment modalities may result in complications for darker skin types. We report a man successfully treated for more than 50 filiform facial warts using a combination of 5-fluorouracil 5% and salicylic acid 20%. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13235
更新日期:2020-03-01 00:00:00
abstract::The skin plays a critical role in the detection of internal malignances. Cutaneous signs of these disorders afford clinicians opportunities for early diagnosis and treatment. We aim to succinctly review the recognition, diagnosis, and treatment of selected cutaneous paraneoplastic diseases. Skin disorders that may be ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2010.01371.x
更新日期:2010-11-01 00:00:00
abstract::Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12571
更新日期:2018-01-01 00:00:00
abstract::Omalizumab is a monoclonal antibody, targeting Fc receptor of IgE, approved for the treatment of allergic asthma and chronic spontaneous urticaria. Its utility in atopic dermatitis appears controversial from data in literature since the molecule is well tolerated but it seems less effective than other medications used...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13519
更新日期:2020-07-01 00:00:00
abstract::Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12503
更新日期:2017-09-01 00:00:00
abstract::It has been reported that dermatology practices may be a vector for SARS-CoV-2 transmission and elective cases should be postponed during the pandemic period. In this context, studies on the change of patient profile in Dermatology outpatient clinic have been conducted. However, there was no study in the literature ab...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13642
更新日期:2020-09-01 00:00:00
abstract::Eccrine porocarcinoma (EPC) is a rare cutaneous neoplasm that grows slowly over a long period of time but often experiences an accelerated growth phase. This malignant tumor may arise denovo or evolve from a pre-existing benign eccrine poroma. Histologic evaluation demonstrates anaplastic cells involving the epidermis...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2008.00243.x
更新日期:2008-11-01 00:00:00
abstract::The Dangguikushen (DGKS) pill is a proprietary traditional Chinese medicine that has shown superior efficacy in the treatment of acne vulgaris for many years. A network pharmacology-based analysis was performed to explore the potential anti-acne compounds, core therapeutic targets, and the main pathways, involved in t...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14061
更新日期:2020-11-01 00:00:00
abstract::Both in the topical and systemic treatment of psoriasis, retinoids are mainstays. In this chapter the history and modes of actions of retinoids are presented. Tazarotene and acitretin are the only retinoids that are available in both topical and systemic formulations. A more extensive description of their pharmacology...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2006.00082.x
更新日期:2006-09-01 00:00:00
abstract::Up until now, real-life experiences on the efficacy of risankizumab in patients who had previously failed anti-IL17, anti-IL12/23 or anti-IL23 inhibitor are not reported. We carried out a single-center, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14144
更新日期:2020-11-01 00:00:00
abstract::The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00224.x
更新日期:2008-09-01 00:00:00
abstract::Paronychia has been described as a side effect in patients undergoing treatment with MEK (mitogen activated protein kinase enzyme) inhibitors. It is usually a recurrent condition that can have a significant impact in the quality of life. Topical beta blocker treatment has been described as an effective therapy in anti...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13164
更新日期:2020-01-01 00:00:00
abstract::Generalized eruptive keratoacanthoma, is considered a serious condition because the eruptions are diffuse, persistent, and recurrent. Constant pruritus, visceral neoplasms, and unsatisfactory response to treatment are ominous prognostic factors. Even if skin cancers are usually well controlled with surgical and/or rad...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12374
更新日期:2016-09-01 00:00:00
abstract::The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...
journal_title:Dermatologic therapy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1529-8019.2008.00235.x
更新日期:2008-11-01 00:00:00
abstract::The safety of methotrexate in psoriasis patients with metabolic syndrome could be argued because of increased risk of liver toxicity. The aim of the study was to investigate the safety of methotrexate compared with secukinumab in psoriasis patients with metabolic syndrome. A controlled, open trial in psoriasis patient...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14281
更新日期:2020-11-01 00:00:00
abstract::For effective treatment of vitiligo, it is as important to arrest the progression of the disease, as it is to induce repigmentation. Epidermal oxidative stress has been documented in vitiligo patients, and there is much support for a free-radical-mediated damage as an initial pathogenic event in melanocyte degeneratio...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2010.01328.x
更新日期:2010-05-01 00:00:00
abstract::In view of the new viral COVID-19 pandemic, the fungal Candida auris epidemic still in progress worldwide highlights non-Candida albicans candidal infections. We describe an immunocompetent woman with a cutaneous manifestation of Candida parasilopsis fungemia, a prominent eschar, which proved to be the nidus for the c...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13481
更新日期:2020-07-01 00:00:00
abstract::Surgery as treatment for local invasive cutaneous squamous cell carcinoma (cSCC) is not always feasible due to the age and/or the health status of patients. Thus, the investigation of new strategies to improve the quality of life of them is required. The aim of this work is to investigate two chemotherapy agents indiv...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12373
更新日期:2016-09-01 00:00:00
abstract::Acitretin has been used off-label for years to treat chronic hand eczema, but acitretin is less often prescribed as alitretinoïne was approved. This study evaluates both retinoids in a daily practice cohort of patients with severe chronic hand eczema in terms of drug survival and reasons for discontinuation. Patients ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12362
更新日期:2016-09-01 00:00:00
abstract::Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe adverse cutaneous drug reaction with mortality up to 10%. It is a rare condition with risk varying between 1 in 1000 and 1 in 10 000 drug exposures. The aim of the study was to describe clinical features, management and drugs responsible for cau...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14670
更新日期:2020-12-14 00:00:00
abstract::Lyophilized-growth factors (L-GFs), is a new platelet rich plasma (PRP) preparation that is standardized in growth factors concentrations. The aim of this study was to compare the therapeutic efficacy of ablative fractional CO2 laser in combination with L-GFs vs PRP in post-acne scars. This study was conducted on 45 p...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14488
更新日期:2020-11-01 00:00:00
abstract::The ultraviolet (UV) light spectrum has long been known to induce biologic effect on the skin. For a large number of cutaneous disorders, phototherapy and photochemotherapy are effective therapeutic options with excellent safety profiles and well-documented side effects. Despite their ease of administration and benefi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2009.01292.x
更新日期:2010-01-01 00:00:00
abstract::This is the first report of a case of porocarcinoma that was successfully treated with maxacalcitol and imiquimod. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.12830
更新日期:2019-03-01 00:00:00
abstract::Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13184
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:There are conflicting results in the literature regarding the frequency of allergic diseases in COVID-19 patients. The effect of having an allergic disease on COVID-19 disease severity has been little studied. In this study, we tried to determine the frequency of allergic diseases in COVID-19 patients and th...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14581
更新日期:2020-11-25 00:00:00
abstract::Tumor necrosis factor-alpha (TNF)-alpha inhibitors are licensed for patients with severe refractory psoriasis and psoriatic arthritis. However, TNF-alpha inhibitors have also been used off-label for various recalcitrant mucocutaneous diseases. This study aimed to evaluate the efficacy and safety of TNF-alpha inhibitor...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12222
更新日期:2015-05-01 00:00:00
abstract::The objective of our study was to describe the effectiveness and safety of oral dutasteride (OD) for male androgenetic alopecia in real clinical practice. A retrospective, monocentric, and descriptive study was designed. Male patients with androgenetic alopecia that had received OD for at least 12 months were included...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13182
更新日期:2020-01-01 00:00:00
abstract::Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12309
更新日期:2016-03-01 00:00:00
abstract::A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12724
更新日期:2018-11-01 00:00:00