Landscape of current and future therapies of Merkel cell carcinoma.

abstract：:Papillon-Lefèvre syndrome (PLS) is a rare disorder characterized by diffuse palmoplantar erythematous, fissured hyperkeratosis, and aggressive periodontal disease that starts in the early periods of childhood. Periodontal disease occurs with the early loss of deciduous teeth at the age of 2 to 4 years, followed by the...

journal_title：Dermatologic therapy

authors： Giannetti L,Apponi R,Dello Diago AM,Jafferany M,Goldust M,Sadoughifar R

更新日期：2020-05-01 00:00:00

abstract：:The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...

journal_title：Dermatologic therapy

authors： Rossi R,Assad GB,Buggiani G,Lotti T

更新日期：2008-09-01 00:00:00

abstract：:Cyclosporine A (CYA) belongs to calcineurin inhibitor family, which has the ability to selectively suppress T cells. Owing to its immune-modulatory effects, it had been in use for graft vs host diseases and organ transplant rejection for many years, but in dermatology, it was first approved for use in 1997 in the trea...

journal_title：Dermatologic therapy

authors： Amber T,Tabassum S

更新日期：2020-11-01 00:00:00

abstract：:Acrodermatitis continua of Hallopeau (ACH) is a rare pustular psoriasis variant refractory to many conventional treatments. We report the successful treatment with secukinumab of a patient with a long history of ACH with marked onychodystrophy with frank pustulosis on the nail bed and with accompanying arthritis. Bloc...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...

journal_title：Dermatologic therapy

authors： Asilian A,Kazemipour S,Mokhtari F,Iraji F,Shahmoradi Z,Mohaghegh F,Mozafarpoor S,Talakoub M

更新日期：2021-01-05 00:00:00

abstract：:Up until now, real-life experiences on the efficacy of risankizumab in patients who had previously failed anti-IL17, anti-IL12/23 or anti-IL23 inhibitor are not reported. We carried out a single-center, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously...

journal_title：Dermatologic therapy

authors： Megna M,Fabbrocini G,Ruggiero A,Cinelli E

更新日期：2020-11-01 00:00:00

abstract：:Intralesional methotrexate (il-MTX) has been reported as a useful therapy in keratoacanthoma (KA) and cutaneous squamous cell carcinoma (cSCC). However, the data available on the histological changes induced by this therapy are very scarce. We conducted a single center, prospective study that included 65 cases of cSCC...

journal_title：Dermatologic therapy

authors： Bergón-Sendín M,Parra-Blanco V,Pulido-Pérez A,Nieto-Benito LM,Rosell-Díaz ÁM,Suárez-Fernández R

更新日期：2020-11-01 00:00:00

abstract：:Successful treatment of Hailey-Hailey disease with intradermal botulinum toxin injections has been previously reported. The main disadvantages of this treatment are the excruciating pain and the risk of infections due to the numerous injections. We sought to evaluate the clinical effectiveness and safety profile of a ...

journal_title：Dermatologic therapy

authors： Bar-Ilan E,Koren A,Shehadeh W,Mashiah J,Sprecher E,Artzi O

更新日期：2020-01-01 00:00:00

abstract：:Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR)...

journal_title：Dermatologic therapy

authors： Fawzy MM,Nofal A,Alakad R

更新日期：2020-11-01 00:00:00

abstract：:To evaluate the preventive practices in family members of melanoma patients regarding melanoma in Turkey and compare our results with similar studies by a literature review. A questionnaire-based, cross-sectional study was conducted in 52 participants over the age of 18 years. The questionnaire consisted of the items ...

journal_title：Dermatologic therapy

authors： Sarikaya Solak S,Yondem H,Cicin I

更新日期：2020-11-01 00:00:00

abstract：:Epidermolytic acanthoma is an uncommon benign tumor with a predilection for the anogenital region, that is characterized histologically by epidermolytic hyperkeratosis. Most reported cases are asymptomatic while some are pruritic. Treatment of this condition is challenging and not well studied. We report a 55-year-old...

journal_title：Dermatologic therapy

authors： Tan GF,Tan ES,Tey HL

更新日期：2014-03-01 00:00:00

abstract：:To date, the geographical distribution and global trends of search activities on psoriasis and atopic eczema on Google and YouTube are widely unknown. The aim of this study was to identify geographic and temporal trends in YouTube and Google search activities for psoriasis and atopic eczema. We used specific filter se...

journal_title：Dermatologic therapy

authors： Hongler VNS,Navarini A,Brandt O,Goldust M,Mueller SM

更新日期：2020-07-01 00:00:00

abstract：:Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...

journal_title：Dermatologic therapy

authors： Juzlova K,Votrubova J,Kacerovska D,Lukas M,Bortlik M,Rohacova H,Nohynkova E,Vojackova N,Fialova J,Hercogova J

更新日期：2014-05-01 00:00:00

abstract：:Adult colloid milium is a rare cutaneous deposition disorder that frequently involves areas of chronic sun exposure. The most common clinical presentation exhibits multiple, firm, and amber-colored papules that cluster to form large plaques. Histologically, there are masses of amorphous, eosinophilic material expandin...

journal_title：Dermatologic therapy

authors： Li YL,Luo YJ,Wu Y,Li B,Gao XH,Chen HD,Li JH

更新日期：2014-03-01 00:00:00

abstract：:The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...

journal_title：Dermatologic therapy

authors： Toth DP,Papp K,Gratton D

更新日期：2008-11-01 00:00:00

abstract：:Plantar warts can cause pain near the toes and the sole of the foot and may result in referral for treatment. This study was aimed at comparing 40% trichloroacetic acid (TCA) and cryotherapy (Cryo) for the treatment of plantar warts. This single-blind, randomized clinical trial was performed on 60 subjects presenting ...

journal_title：Dermatologic therapy

authors： Karrabi M,Kheirkhah M,Shahrestanaki E,Thomas S,Sahebkar M

更新日期：2020-07-01 00:00:00

abstract：INTRODUCTION:Androgenetic Alopecia (AGA) with its precursor Miniaturization of Anagen phase (MA), and Telogen Effluvium (TE) represent non-scarring hair loss diseases which causes moderate to severe aesthetic and psychologic discomfort in affected people. Several therapeutic approaches have been tested through the late...

journal_title：Dermatologic therapy

authors： Piccolo D,Crisman G,Conforti C,Buzzi M,Genovesi C,Marchi D,Mazzaracchio D,Goldust M

更新日期：2021-01-24 00:00:00

abstract：:Covering wounds, acute and chronic, is one of the most fundamental activities of any medical practitioner. Although wound dressings primarily serve to contain the "good" and keep out the "bad," research has characterized more specifically the sophisticated interaction between the human wound bed and its dressing count...

journal_title：Dermatologic therapy

authors： Powers JG,Morton LM,Phillips TJ

更新日期：2013-05-01 00:00:00

abstract：:It is not common for dermatologists to use intravenous antibiotics in daily practice. However, there are several serious infections that may come to the attention of a dermatologist because of cutaneous signs and symptoms. It is important for dermatologists to be familiar with the presenting symptoms, various stages o...

journal_title：Dermatologic therapy

authors： Sambrano B,Gordon R,Mays R,Lapolla W,Scheinfeld N

更新日期：2012-01-01 00:00:00

abstract：:Vitiligo is quite a common hypopigmentary disorder, which may affect both children and adults with important psychological effects due to the well-known leopard skin-like appearance. The authors summarize in the present study the published evidence on vitiligo with particular interest on the controversial aspects of t...

journal_title：Dermatologic therapy

authors： Lotti T,Gianfaldoni S,Valle Y,Rovesti M,Feliciano C,Satolli F

更新日期：2019-01-01 00:00:00

abstract：:Ultrapotent topical corticosteroids and circumcision are usually effective for male genital lichen sclerosus (MGLSc); however, refractory cases are often referred to our Male Genital Dermatology Unit. Treatment with autologous platelet-rich plasma (TPRP) has recently been advocated as a safe and effective treatment op...

journal_title：Dermatologic therapy

authors： Navarrete J,Echarte L,Sujanov A,Guillones A,Vola M,Bunker CB,Agorio C,Touriño C

更新日期：2020-11-01 00:00:00

abstract：:Despite the high prevalence of pulmonary tuberculosis worldwide, extrapulmonary tuberculosis especially cutaneous and osteoarticular tuberculosis occurs rarely, both of which are often difficult to be recognized since their symptoms mimic those of many other cutaneous and osteoarticular diseases. Here, we present a ra...

journal_title：Dermatologic therapy

authors： Li Z,Wang S,Chen X,Ming X,Peng L,Li W

更新日期：2018-07-01 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...

journal_title：Dermatologic therapy

authors： Subedi S,Yu Q,Chen Z,Shi Y

更新日期：2018-01-01 00:00:00

abstract：:Pemphigus is a group of autoimmune diseases characterized by the formation of erosions and/or flaccid bullae of the skin and/or mucosae. The definition "drug-induced pemphigus" has been coined to indicate cases of pemphigus with clinical, histological and immunopathologic features similar to those of the idiopathic di...

journal_title：Dermatologic therapy

authors： Palleria C,Bennardo L,Dastoli S,Iannone LF,Silvestri M,Manti A,Nisticò SP,Russo E,De Sarro G

更新日期：2019-01-01 00:00:00

abstract：:Spontaneous remission occurs in less than 10% of patients suffering from alopecia areata (AA) totalis for more than 2 years. The efficacy of PUVA therapy is controversial due to recurrence of hair loss after cessation. We report two cases presenting with AA totalis and AA universalis. After hair regrowth, relapse of h...

journal_title：Dermatologic therapy

authors： Lux-Battistelli C

更新日期：2015-07-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:Male cosmetic patients represent a growing population of individuals who can substantially benefit from well-chosen esthetic interventions. Understanding some of the unique aspects of the male psyche can result in more effective recruitment of male cosmetic patients and aid the clinician in helping these patients to c...

journal_title：Dermatologic therapy

authors： Fried RG

更新日期：2007-11-01 00:00:00

abstract：:Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...

journal_title：Dermatologic therapy

authors： Agha R,Mirowski GW

更新日期：2010-05-01 00:00:00

abstract：:Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...

journal_title：Dermatologic therapy

authors： Taraz M,Niknam S,Ehsani AH

更新日期：2017-05-01 00:00:00