Unlocking the mystery of persistent skin ulcers in a young man and successful treatment with a simple regimen.

abstract：:The world is facing a viral pandemic of a new coronavirus called COVID-19. Pentoxifylline is a methyl-xanthine derivative and it inhibits the phosphodiesterase IV (PDE IV). This drug is known for its unique features as an immunomodulatory and anti-inflammatory agent, also it could have antiviral affects. This is a sco...

journal_title：Dermatologic therapy

authors： Seirafianpour F,Mozafarpoor S,Fattahi N,Sadeghzadeh-Bazargan A,Hanifiha M,Goodarzi A

更新日期：2020-07-01 00:00:00

abstract：:Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...

journal_title：Dermatologic therapy

authors： Zackheim HS

更新日期：2003-01-01 00:00:00

abstract：INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...

journal_title：Dermatologic therapy

authors： Montero-Vilchez T,Salvador-Rodriguez L,Sanchez-Diaz M,Cuenca-Barrales C,Martinez-Lopez A,Arias-Santiago S,Molina-Leyva A

更新日期：2020-11-01 00:00:00

abstract：:Psoriasis and psoriatic arthritis (PsA) have been linked to metabolic syndrome (MS). The impact of adipokines on psoriasis, PsA, and MS pathogenesis has recently received investigative attention. A total of 80 subjects with psoriasis, 40 subjects with PsA, and 60 healthy controls were enrolled. Serum omentin and visfa...

journal_title：Dermatologic therapy

authors： Dağdelen D,Karadag AS,Kasapoğlu E,Wang JV,Erman H

更新日期：2020-11-01 00:00:00

abstract：:Tinea pedis affects the life quality distinctly and patients those with a prolonged disease often resort to non-medical methods. We sought to evaluate patients' knowledge about tinea pedis and approaches to the non-pharmacological agents. A cross-sectional study was conducted on 152 patients with tinea pedis who answe...

journal_title：Dermatologic therapy

authors： Kara Polat A,Akın Belli A,Göre Karaali M,Koku Aksu AE

更新日期：2020-11-01 00:00:00

abstract：:Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...

journal_title：Dermatologic therapy

authors： Barrett ME,Heller MM,Fullerton Stone H,Murase JE

更新日期：2013-07-01 00:00:00

abstract：:Hand-foot syndrome (HFS) is a specific cutaneous toxicity caused by a variety of antitumor drugs. The most common drugs include capecitabine, pegylated liposomal doxorubicin and fluorouracil (PLD), tyrosine kinase inhibitor. It is a dose-limiting cutaneous toxicity of these drugs. We reported an advanced lung adenocar...

journal_title：Dermatologic therapy

authors： Ren Y,Li T,Du LY,Qiu Y,Wang SB,Lei KJ,Jia YM

更新日期：2020-03-01 00:00:00

abstract：:Growth factors play an important role in reversing the effects of skin aging mediated by chronological and environmental factors. Excessive oxidation of intra- and extracellular components result in breakdown of collagen and elastin network in the dermis and produce the effect of facial aging. Topical application of h...

journal_title：Dermatologic therapy

authors： Mehta RC,Fitzpatrick RE

更新日期：2007-09-01 00:00:00

abstract：:Most studies of oral oxybutynin (OOx) for the treatment of hyperhidrosis (HH) have assumed a stable treatment protocol, without taking into account adverse effects (AE) or seasonal variations in temperature. The objective is to evaluate adjusting the dose of OOx according to the time of year. Prospective study of pati...

journal_title：Dermatologic therapy

authors： Del Boz J,Millán-Cayetano JF,García-Montero P,García-Harana C,Rivas-Ruiz F,de Troya-Martín M

更新日期：2018-07-01 00:00:00

abstract：:Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2014-07-01 00:00:00

abstract：:Intralesional immunotherapy by different antigens has shown promising efficacy and safety in the treatment of warts. However, the use of these antigens for the treatment of plane warts has been investigated in two studies only. To evaluate the efficacy and safety of three antigens; Measles Mumps, Rubella vaccine (MMR)...

journal_title：Dermatologic therapy

authors： Fawzy MM,Nofal A,Alakad R

更新日期：2020-11-01 00:00:00

abstract：:Psoriatic patients with latent tuberculosis infection (LTBI) need a prophylaxis before starting a treatment with biological drugs. The aim of this study is to investigate the safety and efficacy of prophylaxis of LTBI in psoriatic patients receiving long-term biological drugs. The study included 56 patients (42 male a...

journal_title：Dermatologic therapy

authors： Conti A,Piaserico S,Gisondi P,Odorici G,Galdo G,Lasagni C,Pellacani G

更新日期：2017-09-01 00:00:00

abstract：:Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...

journal_title：Dermatologic therapy

authors： Asilian A,Kazemipour S,Mokhtari F,Iraji F,Shahmoradi Z,Mohaghegh F,Mozafarpoor S,Talakoub M

更新日期：2021-01-05 00:00:00

abstract：:Management of keloid is difficult, so there is always a need for adequate and effective therapy. In this study, we explored and compared the efficacy and synergistic effect of combined intralesional radiofrequency (RF) and intralesional triamcinolone acetonide (TAC) with intralesional triamcinolone acetonide alone in ...

journal_title：Dermatologic therapy

authors： Kaushal V,Kumar S,Brar BK,Singh A

更新日期：2020-11-01 00:00:00

abstract：:Maffucci syndrome is characterized by multiple benign vascular anomalies and enchondromas present on the distal extremities. Effective treatment options are currently not available for Maffucci syndrome-associated vascular lesions. Sirolimus is a mTOR pathway inhibitor, and has been tried successfully in the treatment...

journal_title：Dermatologic therapy

authors： Gupta V,Mridha AR,Khaitan BK

更新日期：2019-05-01 00:00:00

abstract：:The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...

journal_title：Dermatologic therapy

authors： Toth DP,Papp K,Gratton D

更新日期：2008-11-01 00:00:00

abstract：:Up until now, real-life experiences on the efficacy of risankizumab in patients who had previously failed anti-IL17, anti-IL12/23 or anti-IL23 inhibitor are not reported. We carried out a single-center, retrospective study, to evaluate the efficacy, safety and tolerability of patients under risankizumab who previously...

journal_title：Dermatologic therapy

authors： Megna M,Fabbrocini G,Ruggiero A,Cinelli E

更新日期：2020-11-01 00:00:00

abstract：:Neutrophilic folliculitis is an often overlooked chronic condition characterized by a monomorphic eruption of "sterile" papulopustules. Neutrophilic folliculitis is often refractory to conventional treatment with topical and systemic antibiotics or isotretinoin. We report a case of severe pustular neutrophilic follicu...

journal_title：Dermatologic therapy

authors： Sand FL,Thomsen SF

更新日期：2015-03-01 00:00:00

abstract：:Febrile ulcero-necrotic Mucha-Habermann disease (FUMHD) is a rare subtype of pityriasis lichenoides et varioliformis acuta (only 41 cases described to date), characterized by an acute onset of ulcero-necrotic papules accompanied by high fever and severe constitutional symptoms. We report a case of a 23-year-old man wi...

journal_title：Dermatologic therapy

authors： Marenco F,Fava P,Fierro MT,Quaglino P,Bernengo MG

更新日期：2010-07-01 00:00:00

abstract：:Photodynamic therapy (PDT) is an established nonsurgical treatment for nodular basal cell carcinoma (nBCC). This study compares the clinical, histopathological, and immunohistochemical findings in recurrent nBCC after PDT versus pre-treatment (primary) nBCC. This retrospective study analyzed nodular BCCs treated with ...

journal_title：Dermatologic therapy

authors： Gracia-Cazaña T,Nicolás J,Cerro-Muñoz PA,González S,Juarranz Á,Gilaberte Y

更新日期：2021-01-13 00:00:00

abstract：:For many years, drug therapies were not explicitly studied in the pediatric population. The lack of data forced clinicians to treat children using empiric therapy, often guessing at the treatment dose. In addition to the lack of dosing information, there was no evidence that a product would be safe and efficacious in ...

journal_title：Dermatologic therapy

authors： Mathis L,Rodriguez W

更新日期：2009-05-01 00:00:00

abstract：:Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramati...

journal_title：Dermatologic therapy

authors： Alamri A,Alsenaid A,Ruzicka T,Wolf R

更新日期：2016-05-01 00:00:00

abstract：:The development of effective and well-tolerated biologic therapies has advanced the management of psoriasis by enabling clinicians to treat underlying disease mechanisms. Biologics approved for the treatment of moderate-to-severe psoriasis include three tumor necrosis factor alpha inhibitors and an interleukin-12/inte...

journal_title：Dermatologic therapy

authors： Gaspari AA,Tyring S

更新日期：2015-07-01 00:00:00

abstract：:The Coronavirus Disease 2019 (COVID-19) outbreak significantly affected the clinical practice in hospitals and the management of many diseases. The aim of this study was to evaluate the effect of pandemic-related factors on the severity and course of chronic urticaria (CU). A total of 194 CU patients who were on regul...

journal_title：Dermatologic therapy

authors： Erdem Y,Polat Ekinci A,Altunay IK,Sivaz O,Inal S,Gokalp MO,Pehlivan G,Özkaya E

更新日期：2020-12-10 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is a rare, systemic inflammatory disorder of not completely understood etiology. Aberrant activation of the innate immune system and overproduction of several pro-inflammatory mediators are considered a critical component in disease pathogenesis. AOSD still poses a challenge due to t...

journal_title：Dermatologic therapy

authors： Wawrzycki B,Krasowska D,Pietrzak A,Wielosz E,Majdan M,Lotti T

更新日期：2019-09-01 00:00:00

abstract：:Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...

journal_title：Dermatologic therapy

authors： Agha R,Mirowski GW

更新日期：2010-05-01 00:00:00

abstract：:Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, there has been an open debate on the impact of biological drugs used in the treatment of psoriasis. To define whether patients under treatment with biologics suffer from increased morbidity and mortality from COVID-19, compared to psoriatic patients ...

journal_title：Dermatologic therapy

authors： Brazzelli V,Isoletta E,Barak O,Barruscotti S,Vassallo C,Giorgini C,Michelerio A,Tomasini CF,Musella V,Klersy C

更新日期：2020-11-01 00:00:00

abstract：:Acne is known as a chronic inflammatory skin disease with sever adverse effects on quality of life in the patients. The increasing resistance to antibiotics has decreased their effectiveness in treating acne. As viable microbial dietary supplements, probiotics provide health benefits through fighting pathogens and mai...

journal_title：Dermatologic therapy

authors： Goodarzi A,Mozafarpoor S,Bodaghabadi M,Mohamadi M

更新日期：2020-05-01 00:00:00

abstract：:Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO(2) laser fluences, by modulating the secret...

journal_title：Dermatologic therapy

authors： Prignano F,Campolmi P,Bonan P,Ricceri F,Cannarozzo G,Troiano M,Lotti T

更新日期：2009-11-01 00:00:00

abstract：:The world entered the year 2020 with reports of the emergence of a new viral illness in Wuhan city, Hubei province, China. In January 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified to be the causative novel coronavirus for the cluster of patients suffering from pneumonia in China. Th...

journal_title：Dermatologic therapy

authors： Kaur I,Sharma A,Jakhar D,Das A,Aradhya SS,Sharma R,Jindal V,Mhatre M

更新日期：2020-07-01 00:00:00