Abstract:
:Verrucas are often recalcitrant to conventional cryotherapy. Since 1970, intralesional bleomycin has been used off-label by dermatologists. But in some cases, the results of intralesional bleomycin were disappointing. Vincristine is a well-known vinca alkaloid antiblastic drug that has been used for treating hematological neoplasm and nephroblastomas. It was reported good efficacy of intralesional vincristine for treating nodular lesion in classic Kaposi sarcoma. Its use in epithelial neoplasm and Kaposi sarcoma may support its efficacy in recalcitrant verrucas. The three patients selected for the study presented severe verrucas on foot, and they had already undergone cryotherapy several times and there was no improvement. They got intralesional vincristine injection on their verrucas. The target lesion was infiltrated with 0.03 mL of vincristine sulphate at a concentration of 1 µg/mL. The injected amount of vincristine was proportional to the diameter of the nodule. After two treatments had been completed, there was a great decrease of lesion size compared with the other lesions. The three patients complained of pain lasting for several days. This pain was generally well tolerated. Intralesional vincristine injection on verruca is an effective and rapid novel method, and when combined with cryotherapy, shows excellent therapeutic response.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Lee JR,Youn JH,Roh JYdoi
10.1111/j.1529-8019.2011.01425.xsubject
Has Abstractpub_date
2011-05-01 00:00:00pages
380-3issue
3eissn
1396-0296issn
1529-8019journal_volume
24pub_type
杂志文章abstract::Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO(2) laser fluences, by modulating the secret...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
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更新日期:2009-11-01 00:00:00
abstract::Past studies have reported associations between psoriasis, metabolic syndrome, and atherosclerotic cardiovascular disease. According to studies, N-terminal pro B-type natriuretic peptide (NT-proBNP) is a useful screening test for cardiac disease. We examined the serum NT-proBNP level in patients with psoriasis and com...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.12865
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2012.01533.x
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abstract::Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...
journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2006.00061.x
更新日期:2006-03-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2011.01434.x
更新日期:2011-07-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12061
更新日期:2014-03-01 00:00:00
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2012.01501.x
更新日期:2012-05-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01343.x
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12040
更新日期:2014-01-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00229.x
更新日期:2008-10-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14544
更新日期:2020-11-14 00:00:00
abstract::Photodynamic therapy (PDT) is an established nonsurgical treatment for nodular basal cell carcinoma (nBCC). This study compares the clinical, histopathological, and immunohistochemical findings in recurrent nBCC after PDT versus pre-treatment (primary) nBCC. This retrospective study analyzed nodular BCCs treated with ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14779
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journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12083
更新日期:2014-05-01 00:00:00
abstract::Psoriasis is a chronic inflammatory condition that often requires life-long treatment. Conventional therapies have not fully met the needs of psoriatic patients, because of limited efficacy, adverse effects with cumulative use, and patient inconvenience. In the past decade, biologic immunotherapies have become accepte...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2009.01259.x
更新日期:2009-09-01 00:00:00
abstract::Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...
journal_title:Dermatologic therapy
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doi:10.1111/dth.14094
更新日期:2020-11-01 00:00:00
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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journal_title:Dermatologic therapy
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更新日期:2008-09-01 00:00:00
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journal_title:Dermatologic therapy
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更新日期:2020-03-01 00:00:00
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journal_title:Dermatologic therapy
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doi:10.1111/dth.12027
更新日期:2013-03-01 00:00:00
abstract::Pruritus is a symptom that significantly affects the patient's quality of life in cutaneous T cell lymphoma (CTCL). The most effective treatments are those that address the condition itself; however, it is often not possible to control this symptom. Lymphoma-related pruritus normally becomes more severe as CTCL progre...
journal_title:Dermatologic therapy
pub_type: 杂志文章
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journal_title:Dermatologic therapy
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更新日期:2004-01-01 00:00:00
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journal_title:Dermatologic therapy
pub_type: 杂志文章
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更新日期:2020-12-14 00:00:00
abstract::Lasers and other light sources are popular treatment options for facial rejuvenation in recent years. In this study, we aimed to compare the efficacy and safety of fractional radiofrequency (RF) and fractional Erbium: YAG (Er:YAG) laser for facial and neck skin wrinkles, objectively. Three hundred and thirty-three pat...
journal_title:Dermatologic therapy
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更新日期:2019-09-01 00:00:00