Abstract:
:Pemphigus encompasses a group of chronic autoimmune blistering diseases of the skin and/or mucosa. Rituximab (RTX) has shown promising efficacy for the treatment of pemphigus in the past decade. Considering potential cardiac side effects, this study was conducted to assess the effects of RTX on electrocardiogram (ECG) parameters in pemphigus patients. This observational cross-sectional study was conducted in 80 consecutive patients with pemphigus who were eligible for RTX infusion. The patients' heart rhythm was monitored before, during and after RTX infusion and ECG parameters were compared before and after the infusion. Eighty patients were included in the study. The median age of the patients was 42 years. The mean and maximum heart rate (HR) increased significantly after RTX infusion compared with pre-infusion mean and maximum HR. The mean corrected QT (QTc) interval, premature atrial contraction (PAC), and premature ventricular contraction (PVC) counts increased significantly after RTX infusion (P value: 0.009, 0.004 and 0.007 respectively). According to the results of this study, RTX has potential arrhythmogenic side effects including increased mean and maximum HR, QTc interval, PAC and PVC count. However, these findings are minor and should not prevent eligible patients from receiving RTX infusion.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Aidi S,Daneshpazhooh M,Eslami M,Azizpour A,Toosi R,Mollazadeh Rdoi
10.1111/dth.14299subject
Has Abstractpub_date
2020-11-01 00:00:00pages
e14299issue
6eissn
1396-0296issn
1529-8019journal_volume
33pub_type
杂志文章abstract::Among different laser types, the carbon dioxide (CO2 ) laser remains one of the most used by dermatologists. Its usefulness has been demonstrated both for therapeutic and cosmetic purposes. This review aims to provide an overview of the applications of CO2 laser in dermatology, focusing on the treatment of infective, ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.14692
更新日期:2020-12-22 00:00:00
abstract::Few studies have reported Fractional Carbon Dioxide (FCO2) laser use in treating alopecia areata (AA), yet, effectiveness of this therapy has not been comparatively analyzed. To assess efficacy and safety of FCO2 laser in comparison to traditional intralesional corticosteroids injection (ILCs) in treatment of AA. This...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13742
更新日期:2020-07-01 00:00:00
abstract::Oral lichen planus (OLP) is a chronic inflammatory disease, has prolonged courses, repeated attacks and resistance to treatment. The traditional narrow spectrum UVB treatment has an established efficacy on skin lichen planus, and high safety. However, most of ultraviolet phototherapy devices have a huge volume, thereb...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12510
更新日期:2017-09-01 00:00:00
abstract::Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00164.x
更新日期:2008-01-01 00:00:00
abstract::The care of patients who have cutaneous melanoma (CM) has undergone a dramatic change during the past five decades. In an increasing majority of cases, CM is being discovered in a premetastatic phase of tumor progression. Most patients are being treated in the ambulatory setting with a minimum of inconvenience and eco...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2005.00056.x
更新日期:2006-01-01 00:00:00
abstract::Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin and mucous membrane injury, which may cause acute and chronic dermatitis, secondary infection and aggravation of underlying skin diseases. This is a consensus of Chinese experts on protective measures and advice on hand-cleaning- ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13310
更新日期:2020-07-01 00:00:00
abstract::Nodular elastosis with cysts and comedones also known as Favre-Racouchot syndrome frequently occurs on actinically damaged skin of middle-aged or elderly Caucasian subjects. The disease usually affects simmetrically the skin mainly around the orbits. Treatment in the past has not been entirely satisfactory. Treatment ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2009.01279.x
更新日期:2010-01-01 00:00:00
abstract::Postherpetic neuralgia (PHN) is a debilitating disease characterized by continuous, intense pain following an outbreak of herpes zoster. The pain associated with PHN can severely affect a patient's quality of life, quality of sleep, and ability to participate in activities of daily living. The aim of this study was to...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13181
更新日期:2020-01-01 00:00:00
abstract::The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...
journal_title:Dermatologic therapy
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1529-8019.2008.00235.x
更新日期:2008-11-01 00:00:00
abstract::Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,随机对照试验
doi:10.1111/dth.12259
更新日期:2015-11-01 00:00:00
abstract::Psoriasis is an inflammatory, immune-mediated cutaneous disorder that has recently been recognized as systemic disease that is associated with multiple comorbidities such as depression, obesity, and the metabolic syndrome. The metabolic syndrome is the constellation of abdominal obesity, dyslipidemia, hypertension and...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01307.x
更新日期:2010-03-01 00:00:00
abstract::Vitiligo is a prevalent destructive melanocyte skin disease that negatively affects the patients' life in terms of self-esteem. Suction blister and dermabrasion plus 5-fluorouracil are effective treatments for vitiligo. The present study was conducted to compare the outcomes of these two techniques. The present clinic...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14750
更新日期:2021-01-05 00:00:00
abstract::Acute urticaria is a self-limited cutaneous condition marked by transient, erythematous, and pruritic wheals. It is a hypersensitivity response that is often secondary to infection, medications, or food allergies in children. In contrast, the urticarial "mimickers" described in this review article are often seen in th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12103
更新日期:2013-11-01 00:00:00
abstract::Keratitis-ichthyosis-deafness (KID syndrome) is a syndromes ichthyoses that is clinically and genetically heterogeneous requiring early and long-term multidisciplinary monitoring of affected individuals. A review of the clinical, etiopathogenic and therapeutic aspects is presented of this rare congenital ectodermal di...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13507
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:To explore the inhibition of the proliferation of vulvar squamous cell carcinoma (VSCC) by astragaloside IV. METHODS:MTT examined the cell proliferation of VSCC. Flow cytometry analyzed cell cycle and apoptosis. Western blot assay detected the expression of some relevant proteins. RESULTS:AS-IV reduced the ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12802
更新日期:2019-07-01 00:00:00
abstract::Photodynamic therapy (PDT), traditionally used in patients with nonmelanoma skin cancer, has been found to be effective for various inflammatory skin conditions. Daylight-activated PDT (DL-PDT), in which the sun serves as the light source, is substantially less painful than conventional PDT. This study aimed to determ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14329
更新日期:2020-11-01 00:00:00
abstract::Smooth, lustrous nails are a sign of health and beauty in our society and fuel the US$6-billion nail salon industry in the United States. Although many women can use nail cosmetics without adverse consequences, when problems occur it is important to recognize the causes and treat the problem condition. The cornerstone...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2007.00111.x
更新日期:2007-01-01 00:00:00
abstract::Treatment of pustular psoriasis in pregnancy is often difficult to manage and is hampered by limited treatment options. We describe herein a patient who was treated with secukinumab after an unsatisfying response to oral steroids and cyclosporin. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13040
更新日期:2019-09-01 00:00:00
abstract::Axillary bromhidrosis has a strong negative effect on one's social life. A high success rate and few complications are criteria for a surgical treatment. The objective of this study was to evaluate a new surgical treatment modality for bromhidrosis: subcutaneous scissor with micropore. Twenty patients with bromhidrosi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12484
更新日期:2017-05-01 00:00:00
abstract::Pigmented lesions represent an enormous range of conditions, from benign to malignant tumors, and from infectious to post-inflammatory. Pigmented lesions are much less easily diagnosed on anogenital skin, and clinicians should have a low threshold for biopsy confirmation of diseases not classic in appearance. ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01349.x
更新日期:2010-09-01 00:00:00
abstract::Despite the high prevalence of pulmonary tuberculosis worldwide, extrapulmonary tuberculosis especially cutaneous and osteoarticular tuberculosis occurs rarely, both of which are often difficult to be recognized since their symptoms mimic those of many other cutaneous and osteoarticular diseases. Here, we present a ra...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12600
更新日期:2018-07-01 00:00:00
abstract::Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12465
更新日期:2017-05-01 00:00:00
abstract::Soft-tissue augmentation with hyaluronic acid and calcium hydroxyl apatite are among the most widely used minimally invasive cosmetic treatments for the correction of contour deficiencies and wrinkles of the face without the risk, recovery time, and expense of a major surgery. Training and experience in the art and sc...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01380.x
更新日期:2011-01-01 00:00:00
abstract::To date, the geographical distribution and global trends of search activities on psoriasis and atopic eczema on Google and YouTube are widely unknown. The aim of this study was to identify geographic and temporal trends in YouTube and Google search activities for psoriasis and atopic eczema. We used specific filter se...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13510
更新日期:2020-07-01 00:00:00
abstract::Ultrapotent topical corticosteroids and circumcision are usually effective for male genital lichen sclerosus (MGLSc); however, refractory cases are often referred to our Male Genital Dermatology Unit. Treatment with autologous platelet-rich plasma (TPRP) has recently been advocated as a safe and effective treatment op...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14032
更新日期:2020-11-01 00:00:00
abstract::Psoriasis is a common dermatosis affecting the skin, mucosal surfaces, and cutaneous adnexa, and joints and bones can be involved at some degree in the clinical features of the disease, configuring psoriatic arthritis. Moderate to severe psoriasis has a high impact on quality of life and requires an integrated and lon...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2008.00229.x
更新日期:2008-10-01 00:00:00
abstract:INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14254
更新日期:2020-11-01 00:00:00
abstract::Isotretinoin is a safe and useful medication for acne management. Adverse effects are mostly related to cutaneous and mucous membranes. We present a case of a 24-year-old female patient who was on treatment with isotretinoin for acne vulgaris Grade 4. After 6 months of treatment, the patient presented with localized p...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13280
更新日期:2020-05-01 00:00:00
abstract::Tattoos have long become a part of human civilization. However, as the number of people who get tattoos increases, so is the number of people who wish to have their tattoos removed. Compared to other methods, laser-based devices are associated with the best efficacy and least side effects in tattoo removal. Lack of un...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.14418
更新日期:2020-10-17 00:00:00
abstract::Surgery as treatment for local invasive cutaneous squamous cell carcinoma (cSCC) is not always feasible due to the age and/or the health status of patients. Thus, the investigation of new strategies to improve the quality of life of them is required. The aim of this work is to investigate two chemotherapy agents indiv...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12373
更新日期:2016-09-01 00:00:00