Abstract:
:Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglandin F2α analogue latanoprost versus tacrolimus when combined with narrow-band ultraviolet B and microneedling in repigmentation of nonsegmental vitiligo lesions. Our results confirm potency of prostaglandins, in particular, that of latanoprost, in inducing repigmentation, with the efficiency being at least comparable to that of tacrolimus, while contribution of microneedling remains unclear. In summary, results of our study provide further evidences for justified use of prostaglandins, in particular, latanoprost, in vitiligo treatment. In turn, this warrants future studies on the topic aiming to conclusively introduce prostaglandin-based formulations as conventional agents for vitiligo management.
journal_name
Dermatol Therjournal_title
Dermatologic therapyauthors
Korobko IV,Lomonosov KMdoi
10.1111/dth.12383subject
Has Abstractpub_date
2016-11-01 00:00:00pages
437-441issue
6eissn
1396-0296issn
1529-8019journal_volume
29pub_type
杂志文章abstract::Experience at the University of California, San Francisco (UCSF), in the management of patch-stage mycosis fungoides (MF) with topical, predominantly high-potency, corticosteroids is reviewed. The technique of applications is discussed in detail. Approximately 200 patients have been treated. The results are very favor...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2003.01639.x
更新日期:2003-01-01 00:00:00
abstract::Severe acute respiratory syndrome-corona virus-2, which causes coronavirus disease 2019 (COVID-19), is highly contagious and a particularly popular problem in all around the World and also in all departments of every hospital. In order to protect the well-being of health care providers while providing a sufficient wor...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13438
更新日期:2020-07-01 00:00:00
abstract::Pruritus is a symptom that significantly affects the patient's quality of life in cutaneous T cell lymphoma (CTCL). The most effective treatments are those that address the condition itself; however, it is often not possible to control this symptom. Lymphoma-related pruritus normally becomes more severe as CTCL progre...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12113
更新日期:2014-05-01 00:00:00
abstract::Itch is an extremely frequent and enervating symptom of many diseases. Current anti-itch therapy, which is based almost exclusively on an "immunocentric" viewpoint, is often unsatisfactory. Recent studies show that this symptom is in fact the result of a complex interplay among skin, nervous system, endocrine system, ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2005.00030.x
更新日期:2005-07-01 00:00:00
abstract:INTRODUCTION:There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. OBJECTIVES:(a) To describe the clinical profile of HS patients receiving first-line biologic treatment in an HS c...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14254
更新日期:2020-11-01 00:00:00
abstract::Vitiligo is a relatively common disorder characterized by areas of depigmented skin. It may be associated with social stigma and adversely affects the quality of life. Although many treatment options are available, none is curable. The search continues for an effective therapeutic option. New targeted options include ...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13215
更新日期:2020-03-01 00:00:00
abstract::Plantar warts are a common reason for dermatological consultations and their treatment can occasionally be a challenge. Plantar warts are benign lesions produced by the human papillomavirus (HPV) that often fail to respond to habitual treatment. Cidofovir is a potent antiviral drug that acts competitively, inhibiting ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12061
更新日期:2014-03-01 00:00:00
abstract::Treatment of pustular psoriasis in pregnancy is often difficult to manage and is hampered by limited treatment options. We describe herein a patient who was treated with secukinumab after an unsatisfying response to oral steroids and cyclosporin. ...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.13040
更新日期:2019-09-01 00:00:00
abstract::Acne cysts are a common dermatological problem that often leads to scarring and a significant negative impact on patients' psyche. The aim of the study was to evaluate the usefulness of intralesional foam sclerotherapy for the treatment of cystic acne. Patients with cystic acne treated with intralesional foam scleroth...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13505
更新日期:2020-11-01 00:00:00
abstract::Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are medication-induced in most instances. While the clinical manifestations of SJS and TEN are well-defined, the optimal treatment for these disorders is not. Case reports have shown benefit with the use of a variet...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1529-8019.2011.01396.x
更新日期:2011-03-01 00:00:00
abstract::Cutaneous necrotizing vasculitis is a heterogeneous group of disorders characterized clinically by palpable purpura, and histologically by a segmental angiocentric inflammatory condition with fibrinoid necrosis of the vessel wall, endothelial swelling, and nuclear dust of the post capillary venules. Often, the skin se...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2012.01480.x
更新日期:2012-07-01 00:00:00
abstract::It has been reported that dermatology practices may be a vector for SARS-CoV-2 transmission and elective cases should be postponed during the pandemic period. In this context, studies on the change of patient profile in Dermatology outpatient clinic have been conducted. However, there was no study in the literature ab...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13642
更新日期:2020-09-01 00:00:00
abstract::Alternative methods are commonly used in patients with dermatologic diseases, with homeopathy being one of the most common. Homeopathy was developed by Samuel Hahnemann (1755-1843) and is based on the law of similars and the law of infinitesimals. It is a regulatory therapy where high dilutions of particular compounds...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1046/j.1529-8019.2003.01616.x
更新日期:2003-01-01 00:00:00
abstract::Hydrogels based on hyaluronic acid are used to restore volume, hydration, and skin tone, as well as to correct scars, asymmetries or defects of the soft tissue. Hyaluronic acid is often chemically crosslinked with different crosslinking agents in order to improve its mechanical and biological properties. Here we focus...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.13747
更新日期:2020-07-01 00:00:00
abstract::Psoriasis of the scalp, face, intertriginous areas, genitals, hands, feet, and nails is often underdiagnosed, and disease management can be challenging. Despite the small surface area commonly affected by psoriasis in these locations, patients have disproportionate levels of physical impairment and emotional distress....
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12589
更新日期:2018-05-01 00:00:00
abstract::Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12571
更新日期:2018-01-01 00:00:00
abstract::Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramati...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12337
更新日期:2016-05-01 00:00:00
abstract::The incidences of fungal infections have greatly increased over the past few years, particularly in humid and industrialized areas. The severity of such infections ranges from being asymptomatic-mild to potentially life-threatening systemic infections. There are limited classes of drugs that are approved for the treat...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.13905
更新日期:2020-11-01 00:00:00
abstract::Dermatoses of the breast during lactation can be difficult to diagnose because of their overlapping clinical appearances. It is important to properly diagnose and treat nipple dermatitis since it can be a significant source of pain when nursing. Poorly controlled nipple pain in nursing mothers is one of the primary re...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12071
更新日期:2013-07-01 00:00:00
abstract::Hand dermatitis is a common skin condition that often has a chronic and/or relapsing clinical course. Several clinical forms of hand dermatitis have been described, including contact (i.e., allergic and irritant), hyperkeratotic (i.e., psoriasiform or tylotic), frictional, nummular, atopic, pompholyx (i.e., dyshidrosi...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/j.1396-0296.2004.04025.x
更新日期:2004-01-01 00:00:00
abstract::Necrobiosis lipoidica diabeticorum is a granulomatous skin disease of uncertain pathogenesis. Many therapeutic approaches have been reported in the literature, but none of them can be considered the gold standard. Fractional CO(2) laser treatment shows peculiar effects in the skin, mainly due to its ability of modula...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2012.01531.x
更新日期:2012-11-01 00:00:00
abstract::The Coronavirus Disease 2019 (COVID-19) outbreak significantly affected the clinical practice in hospitals and the management of many diseases. The aim of this study was to evaluate the effect of pandemic-related factors on the severity and course of chronic urticaria (CU). A total of 194 CU patients who were on regul...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14652
更新日期:2020-12-10 00:00:00
abstract::Despite the high prevalence of pulmonary tuberculosis worldwide, extrapulmonary tuberculosis especially cutaneous and osteoarticular tuberculosis occurs rarely, both of which are often difficult to be recognized since their symptoms mimic those of many other cutaneous and osteoarticular diseases. Here, we present a ra...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.12600
更新日期:2018-07-01 00:00:00
abstract::Topical and intralesional corticosteroids (CS) are effective treatments for oral manifestations of autoimmune vesiculobullous diseases (VBD); however, may cause unnecessary absorption in the adjacent healthy mucosal surfaces, local infections, atrophy, and injection pain. To propose a protocol using a unique modality ...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/dth.14446
更新日期:2020-11-01 00:00:00
abstract::In the past decade, the expanded use of targeted anticancer drugs has significantly prolonged survival in patients treated for a variety of cancers. Despite their increased specificity, agents such as epidermal growth factor receptor inhibitors (EGFRIs), BRAF inhibitors, and targeted immunotherapies have commonly been...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12027
更新日期:2013-03-01 00:00:00
abstract::Febrile ulcero-necrotic Mucha-Habermann disease (FUMHD) is a rare subtype of pityriasis lichenoides et varioliformis acuta (only 41 cases described to date), characterized by an acute onset of ulcero-necrotic papules accompanied by high fever and severe constitutional symptoms. We report a case of a 23-year-old man wi...
journal_title:Dermatologic therapy
pub_type: 杂志文章
doi:10.1111/j.1529-8019.2010.01343.x
更新日期:2010-07-01 00:00:00
abstract::The development of effective and well-tolerated biologic therapies has advanced the management of psoriasis by enabling clinicians to treat underlying disease mechanisms. Biologics approved for the treatment of moderate-to-severe psoriasis include three tumor necrosis factor alpha inhibitors and an interleukin-12/inte...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12251
更新日期:2015-07-01 00:00:00
abstract::Maffucci syndrome is characterized by multiple benign vascular anomalies and enchondromas present on the distal extremities. Effective treatment options are currently not available for Maffucci syndrome-associated vascular lesions. Sirolimus is a mTOR pathway inhibitor, and has been tried successfully in the treatment...
journal_title:Dermatologic therapy
pub_type: 信件
doi:10.1111/dth.12851
更新日期:2019-05-01 00:00:00
abstract::Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO(2) laser fluences, by modulating the secret...
journal_title:Dermatologic therapy
pub_type: 临床试验,杂志文章
doi:10.1111/j.1529-8019.2009.01265.x
更新日期:2009-11-01 00:00:00
abstract::Acute urticaria is a self-limited cutaneous condition marked by transient, erythematous, and pruritic wheals. It is a hypersensitivity response that is often secondary to infection, medications, or food allergies in children. In contrast, the urticarial "mimickers" described in this review article are often seen in th...
journal_title:Dermatologic therapy
pub_type: 杂志文章,评审
doi:10.1111/dth.12103
更新日期:2013-11-01 00:00:00