Maculopapular eruptions associated to COVID-19: A subanalysis of the COVID-Piel study.

Abstract:

:A previous study has defined the maculopapular subtype of manifestations of COVID-19. The objective of our study was to describe and classify maculopapular eruptions associated with COVI-19. We carried out a subanalysis of the maculopapular cases found in the previous cross-sectional study. Using a consensus, we defined seven clinical patterns. We described patient demographics, the therapy received by the patient and the characteristics of each pattern. Consensus lead to the description of seven major maculopapular patterns: morbilliform (45.5%), other maculopapular (20.0%), purpuric (14.2%), erythema multiforme-like (9.7%), pytiriasis rosea-like (5.7%), erythema elevatum diutinum-like (2.3%), and perifollicular (2.3%). In most cases, maculopapular eruptions were coincident (61.9%) or subsequent (34.1%) to the onset of other COVID-19 manifestations. The most frequent were cough (76%), dyspnea (72%), fever (88%), and astenia (62%). Hospital admission due to pneumonia was frequent (61%). Drug intake was frequent (78%). Laboratory alterations associated with maculo-papular eruptions were high C-reactive protein, high D-Dimer, lymphopenia, high ferritin, high LDH, and high IL-6. The main limitation of our study was the impossibility to define the cause-effect relationship of each pattern. In conclusion, we provide a description of the cutaneous maculopapular manifestations associated with COVID-19. The cutaneous manifestations of COVID-19 are wide-ranging and can mimic other dermatoses.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Català A,Galván-Casas C,Carretero-Hernández G,Rodríguez-Jiménez P,Fernández-Nieto D,Rodríguez-Villa A,Navarro-Fernández Í,Ruiz-Villaverde R,Falkenhain-López D,Llamas-Velasco M,Carnero-Gonzalez L,García-Gavin J,Baniandrés O,Gonz

doi

10.1111/dth.14170

subject

Has Abstract

pub_date

2020-11-01 00:00:00

pages

e14170

issue

6

eissn

1396-0296

issn

1529-8019

journal_volume

33

pub_type

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