Rare atopy in COVID-19 patients or COVID-19 famine in atopic patients?

Abstract:

BACKGROUND:There are conflicting results in the literature regarding the frequency of allergic diseases in COVID-19 patients. The effect of having an allergic disease on COVID-19 disease severity has been little studied. In this study, we tried to determine the frequency of allergic diseases in COVID-19 patients and the effect of having an allergic disease on COVID-19 disease severity. METHODS:A retrospective cross-sectional study was conducted in patients diagnosed with COVID-19 in a state hospital in Istanbul, Turkey. Patients were contacted by phone and those who approved to participate in the study were questionned about their sociodemographic characteristics, body-mass index, smoking history, and about their atopic status. Rate of atopic diseases among mild and severe COVID-19 patients and risk estimates for mild disease in atopic and non-atopic COVID-19 patients were calculated. RESULTS:Study population consisted of 235 adults with COVID-19 (mean age, 45.3 years [standard deviation, 15.0 years]; 139 (59.1%) male). Among study population 16 (6.8%) subjects had one of the three atopic symptoms which were wheezing, rhinitis or eczema. Among the subjects with atopic status 4 (1.7%) subjects had wheezing, 8 (3.4%) had rhinitis and 4 (1.7%) had eczema within the last 12 months. Although atopic status is associated with 3.1 times higher odds for mild disease, being atopic or not being atopic was not found to be associated with COVID-19 severity (p=.054). CONCLUSION:The information that atopic diseases are less common in COVID-19 patients may guide clinical risk classification. This article is protected by copyright. All rights reserved.

journal_name

Dermatol Ther

journal_title

Dermatologic therapy

authors

Naziroğlu T,Aksu K

doi

10.1111/dth.14581

subject

Has Abstract

pub_date

2020-11-25 00:00:00

eissn

1396-0296

issn

1529-8019

pub_type

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