Neuroanatomy and neurophysiology of itch.

abstract：:Lichen planus is considered a T cell-mediated immunological disease. Even mast cells may contribute to the pathogenesis of the disease. Keratinocytes of the basal layer of the skin and/or the hair follicle may represent the "target/victim" of an immune aggression, determining the destruction of the hair follicle and t...

journal_title：Dermatologic therapy

authors： d'Ovidio R,Rossi A,Di Prima TM

更新日期：2010-09-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is a rare, systemic inflammatory disorder of not completely understood etiology. Aberrant activation of the innate immune system and overproduction of several pro-inflammatory mediators are considered a critical component in disease pathogenesis. AOSD still poses a challenge due to t...

journal_title：Dermatologic therapy

authors： Wawrzycki B,Krasowska D,Pietrzak A,Wielosz E,Majdan M,Lotti T

更新日期：2019-09-01 00:00:00

abstract：:Treatment of severe psoriasis (PsO) in organ transplant (OT) patients is difficult. In fact, systemic drugs used for PsO therapy can be detrimental to transplanted organs and/or can increase the risk of serious infections in subjects already taking antireject medicines. Current guidelines fail to give indications on h...

journal_title：Dermatologic therapy

authors： Lora V,Graceffa D,De Felice C,Morrone A,Bonifati C

更新日期：2019-05-01 00:00:00

abstract：:Vitiligo progression is attributed to immune system malfunctioning, thus immunomodulating compounds might be beneficial in stopping vitiligo progression which is a prerequisite for successful repigmentation. The goal of this study was to assess efficacy of acridone acetic acid, sodium salt (Na-AAA), an immunomodulatin...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2014-07-01 00:00:00

abstract：:Psoriasis is a chronic skin inflammatory disorder with frequent relapse. Ceramides and their key enzymes are deficient in the lesions, resulting in impaired epidermal permeability barrier, which correlates with disease severity. We evaluated the efficacy of linoleic acid-ceramide moisturizer (LA-Cer) as an adjunctive ...

journal_title：Dermatologic therapy

authors： Liu M,Li X,Chen XY,Xue F,Zheng J

更新日期：2015-11-01 00:00:00

abstract：:Paronychia has been described as a side effect in patients undergoing treatment with MEK (mitogen activated protein kinase enzyme) inhibitors. It is usually a recurrent condition that can have a significant impact in the quality of life. Topical beta blocker treatment has been described as an effective therapy in anti...

journal_title：Dermatologic therapy

authors： Martínez-de-Espronceda I,Bernabeu-Wittel J,Azcona M,Monserrat MT

更新日期：2020-01-01 00:00:00

abstract：:Isotretinoin is an effective therapy for severe nodulocystic acne. Several experimental studies suggest that it may have an effect on vitamin D physiology. In the present study, the authors aimed to investigate the effect of isotretinoin treatment on the metabolism of vitamin D in acne patients. A prospective analysis...

journal_title：Dermatologic therapy

authors： Ertugrul DT,Karadag AS,Tutal E,Akin KO

更新日期：2011-03-01 00:00:00

abstract：:Cyclosporine A (CYA) belongs to calcineurin inhibitor family, which has the ability to selectively suppress T cells. Owing to its immune-modulatory effects, it had been in use for graft vs host diseases and organ transplant rejection for many years, but in dermatology, it was first approved for use in 1997 in the trea...

journal_title：Dermatologic therapy

authors： Amber T,Tabassum S

更新日期：2020-11-01 00:00:00

abstract：:A 57-year-old Caucasian female presented to our clinic with her 23-year-old son, who was profoundly autistic. Our patient was convinced that her son had an infestation with fibers and believed that he had developed the condition as a young child. She described the symptoms of the infestation in her son's skin on his b...

journal_title：Dermatologic therapy

authors： Hussain K,Gkini MA,Taylor R,Shinhmar S,Bewley A

更新日期：2018-11-01 00:00:00

abstract：:Performing an accurate oral examination is an integral part of a complete dermatological evaluation. As dermatologists, we are frequently asked to assess and treat numerous oral pathologies, which include, but are not limited to, normal variants, infections, ulcers, granulomas, lymphomas, as well as primary and metast...

journal_title：Dermatologic therapy

authors： Agha R,Mirowski GW

更新日期：2010-05-01 00:00:00

abstract：:Tumor necrosis-alpha (TNF-alpha) has been implicated in many forms of inflammation and is an end-stage product of the inflammatory cytokine cascade. It is an inducer of inflammation and is involved in many cutaneous and systemic inflammatory diseases. The development of agents that block the effects of TNF-alpha has a...

journal_title：Dermatologic therapy

authors： Jackson JM

更新日期：2007-07-01 00:00:00

abstract：:Infection-induced panniculitis may result from a number of microbes including bacteria, fungi, and parasites. Viruses have also been implicated as a cause. This type of panniculitis can occur as a primary infection by direct inoculation of infectious microorganisms into the subcutaneous tissue, or secondarily via micr...

journal_title：Dermatologic therapy

authors： Morrison LK,Rapini R,Willison CB,Tyring S

更新日期：2010-07-01 00:00:00

abstract：:During the past 20 years, tremendous progress has been made in our understanding of the molecular basis of many genetic skin conditions. The translation of these laboratory findings into effective therapies for affected individuals has been slow, however, in large part due to the risk of carcinogenesis from random vir...

journal_title：Dermatologic therapy

authors： Lai-Cheong JE,Elias PM,Paller AS

更新日期：2013-01-01 00:00:00

abstract：:Vitiligo is a systemic disease that affects not only the skin but also other areas that contain melanocytes, such as the inner ear. Studies of the effect of vitiligo on hearing loss have shown inconsistent results, and it is not clear which parameters related to the disease affect hearing. The aim of this study was to...

journal_title：Dermatologic therapy

authors： Ertugrul G,Ertugrul S,Soylemez E

更新日期：2020-07-01 00:00:00

abstract：:Mycobacterium W (Mw) vaccine has been found to be effective in the treatment of leprosy and warts. Despite increasing use of Mw immunotherapy, data on its safety is limited. We report a series of eight patients who developed persisting injection site granulomatous reaction following Mw immunotherapy and were successfu...

journal_title：Dermatologic therapy

authors： Vinay K,Narang T,Saikia UN,Kumaran MS,Dogra S

更新日期：2017-03-01 00:00:00

abstract：:Acne is known as a chronic inflammatory skin disease with sever adverse effects on quality of life in the patients. The increasing resistance to antibiotics has decreased their effectiveness in treating acne. As viable microbial dietary supplements, probiotics provide health benefits through fighting pathogens and mai...

journal_title：Dermatologic therapy

authors： Goodarzi A,Mozafarpoor S,Bodaghabadi M,Mohamadi M

更新日期：2020-05-01 00:00:00

abstract：:Although acne is not an infectious disease, oral antibiotics have remained a mainstay of treatment over the last 40 years. The anti-inflammatory properties of oral antibiotics, particularly the tetracyclines, are efficacious in treating inflammatory acne lesions. Common prescribing practices in Dermatology exert signi...

journal_title：Dermatologic therapy

authors： Farrah G,Tan E

更新日期：2016-09-01 00:00:00

abstract：:Maffucci syndrome is characterized by multiple benign vascular anomalies and enchondromas present on the distal extremities. Effective treatment options are currently not available for Maffucci syndrome-associated vascular lesions. Sirolimus is a mTOR pathway inhibitor, and has been tried successfully in the treatment...

journal_title：Dermatologic therapy

authors： Gupta V,Mridha AR,Khaitan BK

更新日期：2019-05-01 00:00:00

abstract：:Morgellons disease, a pattern of dermatologic symptoms very similar, if not identical, to those of delusions of parasitosis, was first described many centuries ago, but has recently been given much attention on the internet and in the mass media. The present authors present a history of Morgellons disease, in addition...

journal_title：Dermatologic therapy

authors： Accordino RE,Engler D,Ginsburg IH,Koo J

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:Androgenetic Alopecia (AGA) with its precursor Miniaturization of Anagen phase (MA), and Telogen Effluvium (TE) represent non-scarring hair loss diseases which causes moderate to severe aesthetic and psychologic discomfort in affected people. Several therapeutic approaches have been tested through the late...

journal_title：Dermatologic therapy

authors： Piccolo D,Crisman G,Conforti C,Buzzi M,Genovesi C,Marchi D,Mazzaracchio D,Goldust M

更新日期：2021-01-24 00:00:00

abstract：:Ingrown nail is a common problem seen in the dermatology clinics. The aim of this study is to compare the wedge resection method and chemical matricectomy with NaOH in terms of operation time, postoperative pain severity, postoperative drainage, recurrence rates, recovery time, and the effects of these two methods on ...

journal_title：Dermatologic therapy

authors： Akkus A,Demirseren DD,Demirseren ME,Aktas A

更新日期：2018-09-01 00:00:00

abstract：:Protozoan infections can have a variety of different cutaneous manifestations in addition to systemic signs and symptoms of disease. Recognition and diagnosis can be difficult, as additional laboratory tests, in addition to biopsies, may be required. Treatment options for different protozoa vary and resolution of dise...

journal_title：Dermatologic therapy

authors： Sra KK,Sracic J,Tyring SK

更新日期：2004-01-01 00:00:00

abstract：:Pemphigus encompasses a group of chronic autoimmune blistering diseases of the skin and/or mucosa. Rituximab (RTX) has shown promising efficacy for the treatment of pemphigus in the past decade. Considering potential cardiac side effects, this study was conducted to assess the effects of RTX on electrocardiogram (ECG)...

journal_title：Dermatologic therapy

authors： Aidi S,Daneshpazhooh M,Eslami M,Azizpour A,Toosi R,Mollazadeh R

更新日期：2020-11-01 00:00:00

abstract：:The rise in popularity and demand for nonsurgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimize the potential for cross-contam...

journal_title：Dermatologic therapy

authors： Murthy R,Eccleston D,Mckeown D,Parikh A,Shotter S

更新日期：2020-10-17 00:00:00

abstract：:Psoriasis is a chronic inflammatory disease of the skin which can occur at any age-group. Psoriasis in childhood is not uncommon and has genetic susceptibility but usually, an environmental trigger such as infection is thought to initiate the disease process. Pediatric psoriasis has profound effects on both physical a...

journal_title：Dermatologic therapy

authors： Subedi S,Yu Q,Chen Z,Shi Y

更新日期：2018-01-01 00:00:00

abstract：:Topical and intralesional corticosteroids (CS) are effective treatments for oral manifestations of autoimmune vesiculobullous diseases (VBD); however, may cause unnecessary absorption in the adjacent healthy mucosal surfaces, local infections, atrophy, and injection pain. To propose a protocol using a unique modality ...

journal_title：Dermatologic therapy

authors： Porat Ben Amy D,Kassem R

更新日期：2020-11-01 00:00:00

abstract：:Nail involvement can place a significant burden on patients as a result of functional damage and psychosocial problems, leading to major repercussions on the quality of life. There is strong evidence that nail psoriasis can often be difficult to treat. We report a 69-year-old man with severe onychodystrophy, onycholys...

journal_title：Dermatologic therapy

authors： Galluzzo M,D'Adamio S,Chimenti MS,Teoli M,Bianchi L,Talamonti M

更新日期：2019-05-01 00:00:00

abstract：:The Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling pathway has been linked to the pathogenesis of many inflammatory skin diseases; however, the role of JAKs in the pathogenesis of acne vulgaris has not been previously elucidated. We aimed to analyze the cutaneous expression of JAK1/...

journal_title：Dermatologic therapy

authors： Awad SM,Tawfik YM,El-Mokhtar MA,El-Gazzar AF,Abdel Motaleb AA

更新日期：2020-11-19 00:00:00

abstract：:Treatment of pustular psoriasis in pregnancy is often difficult to manage and is hampered by limited treatment options. We describe herein a patient who was treated with secukinumab after an unsatisfying response to oral steroids and cyclosporin. ...

journal_title：Dermatologic therapy

authors： Chhabra G,Chanana C,Verma P,Saxena A

更新日期：2019-09-01 00:00:00

abstract：:The world is facing a viral pandemic of a new coronavirus called COVID-19. Pentoxifylline is a methyl-xanthine derivative and it inhibits the phosphodiesterase IV (PDE IV). This drug is known for its unique features as an immunomodulatory and anti-inflammatory agent, also it could have antiviral affects. This is a sco...

journal_title：Dermatologic therapy

authors： Seirafianpour F,Mozafarpoor S,Fattahi N,Sadeghzadeh-Bazargan A,Hanifiha M,Goodarzi A

更新日期：2020-07-01 00:00:00