Serum soluble CD163 and proinflammatory chemokines may be biomarkers of the onset of adverse events in dabrafenib plus trametinib combination therapy for advanced melanoma.

abstract：:Prostaglandins and their analogues are beneficial as topical agents in vitiligo treatment, yet neither of the previous study addressed their comparative efficiency with conventional topical agents used in vitiligo treatment. In this pilot (24 patients) left-right comparative study we addressed efficiency of prostaglan...

journal_title：Dermatologic therapy

authors： Korobko IV,Lomonosov KM

更新日期：2016-11-01 00:00:00

abstract：:We report a case of Alternaria alternata cutaneous and pulmonary infection in a 62-year-old man after heart transplantation treated by azole antifungals. Alternaria spp. belong to a group of opportunistic dematiaceous fungi with worldwide distribution. The cutaneous form of the infection in human is very rare and occu...

journal_title：Dermatologic therapy

authors： Sečníková Z,Jůzlová K,Vojáčková N,Kazakov DV,Hošková L,Fialová J,Džambová M,Hercogová J

更新日期：2014-05-01 00:00:00

abstract：:Leishmaniasis is a vector borne disease transmitted by phlebotomine sandflies. Cutaneous leishmaniasis (CL) predominantly causes skin ulcers but may disseminate. CL may present a therapeutic challenge. The present study reports the case of a 15-year old boy with CL consisting of a single, ulcer on the leg, resistant t...

journal_title：Dermatologic therapy

authors： Johansen MB,Jemec GBE,Fabricius S

更新日期：2019-09-01 00:00:00

abstract：:Mycobacterium W (Mw) vaccine has been found to be effective in the treatment of leprosy and warts. Despite increasing use of Mw immunotherapy, data on its safety is limited. We report a series of eight patients who developed persisting injection site granulomatous reaction following Mw immunotherapy and were successfu...

journal_title：Dermatologic therapy

authors： Vinay K,Narang T,Saikia UN,Kumaran MS,Dogra S

更新日期：2017-03-01 00:00:00

abstract：:Psoriasis is a chronic, systemic inflammatory disease that in the moderate to severe forms may benefit of biologics, namely TNF and IL-12/23 and IL-17 inhibitors. Loss of response, lack of response, or discontinuation due to adverse events represent a concrete therapeutic challenge for dermatologists that have to swit...

journal_title：Dermatologic therapy

authors： Damiani G,Conic RRZ,de Vita V,Costanzo A,Regazzini R,Pigatto PDM,Bragazzi NL,Pacifico A,Malagoli P

更新日期：2019-03-01 00:00:00

abstract：:Protozoan infections can have a variety of different cutaneous manifestations in addition to systemic signs and symptoms of disease. Recognition and diagnosis can be difficult, as additional laboratory tests, in addition to biopsies, may be required. Treatment options for different protozoa vary and resolution of dise...

journal_title：Dermatologic therapy

authors： Sra KK,Sracic J,Tyring SK

更新日期：2004-01-01 00:00:00

abstract：:The efficacy and safety of efalizumab in the treatment of moderate-to-severe chronic psoriasis has been established in studies of up to 3 years' duration. This study aims to describe the efficacy of up to 15 months' treatment with efalizumab and the convenience of therapy in patients with moderate-to-severe chronic pl...

journal_title：Dermatologic therapy

authors： Toth DP,Papp K,Gratton D

更新日期：2008-11-01 00:00:00

abstract：:Ischemic complications in cutaneous surgery can be devastating. Tissue ischemia can result from improper technique or closure design (i.e., increased tension), inadequate hemostasis, or infection, all of which result in decreased blood supply to the surgical site. Knowledge of patient characteristics that affect blood...

journal_title：Dermatologic therapy

authors： Delaney A,Diamantis S,Marks VJ

更新日期：2011-11-01 00:00:00

abstract：:Jarisch-Herxheimer reaction (JHR) is an acute and self-limited condition, which commonly occurs after treatment for spirochetal infections. Probably, it corresponds to a transient immunological reaction to endotoxin-like products released from the microorganism during the therapy. For this reason, JHR may be associate...

journal_title：Dermatologic therapy

authors： Muscianese M,Magri F,Pranteda G,Pranteda G

更新日期：2020-03-01 00:00:00

abstract：:Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topi...

journal_title：Dermatologic therapy

authors： Zanardelli M,Kovacevic M,McCoy J,Wang X,Goren A,Lotti T

更新日期：2016-03-01 00:00:00

abstract：:Reflectance confocal microscopy (RCM) enables the noninvasive in vivo imaging of the skin with a horizontal axis and a cellular-level resolution allowing the study of the skin from superficial layers to papillary dermis. It has arisen an important tool in the study of tumors and specially an important role in the char...

journal_title：Dermatologic therapy

authors： Carrera C,Puig S,Malvehy J

更新日期：2012-09-01 00:00:00

abstract：:Skin cancers are the most common type of cancer. Nonmelanoma skin cancers (NMSCs) are more common than melanoma. Although the mortality rate is low, cancer word can be frightening for patients. Surgery is the main treatment. As skin cancers are most commonly located on the face, undesirable cosmetic results can occur ...

journal_title：Dermatologic therapy

authors： Çetinarslan T,Evrenos MK,Bilaç C,Özyurt B,Türel Ermertcan A

更新日期：2020-11-01 00:00:00

abstract：:Ingrown nail is a common problem seen in the dermatology clinics. The aim of this study is to compare the wedge resection method and chemical matricectomy with NaOH in terms of operation time, postoperative pain severity, postoperative drainage, recurrence rates, recovery time, and the effects of these two methods on ...

journal_title：Dermatologic therapy

authors： Akkus A,Demirseren DD,Demirseren ME,Aktas A

更新日期：2018-09-01 00:00:00

abstract：:Intralesional methotrexate (il-MTX) has been reported as a useful therapy in keratoacanthoma (KA) and cutaneous squamous cell carcinoma (cSCC). However, the data available on the histological changes induced by this therapy are very scarce. We conducted a single center, prospective study that included 65 cases of cSCC...

journal_title：Dermatologic therapy

authors： Bergón-Sendín M,Parra-Blanco V,Pulido-Pérez A,Nieto-Benito LM,Rosell-Díaz ÁM,Suárez-Fernández R

更新日期：2020-11-01 00:00:00

abstract：:Photodynamic therapy (PDT), traditionally used in patients with nonmelanoma skin cancer, has been found to be effective for various inflammatory skin conditions. Daylight-activated PDT (DL-PDT), in which the sun serves as the light source, is substantially less painful than conventional PDT. This study aimed to determ...

journal_title：Dermatologic therapy

authors： Kremer N,Sherman S,Lapidoth M,Enk CD,Leshem YA,Mimouni T,Dudkiewicz D,Hodak E,Levi A

更新日期：2020-11-01 00:00:00

abstract：:Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous reactions that are medication-induced in most instances. While the clinical manifestations of SJS and TEN are well-defined, the optimal treatment for these disorders is not. Case reports have shown benefit with the use of a variet...

journal_title：Dermatologic therapy

authors： Worswick S,Cotliar J

更新日期：2011-03-01 00:00:00

abstract：:Psoriasis is associated with an increased risk of atherosclerosis. The objective of this study is evaluate the relationship between carotid intima-media thickness (CIMT) serum and cystatin-C, fetuin-A levels in determining the increased risk of subclinical atherosclerosis in psoriasis patients. In this study, age and ...

journal_title：Dermatologic therapy

authors： Demirbaş A,Kurtipek GS,Tunçez A,Akyürek F,Demirbaş GU

更新日期：2020-11-01 00:00:00

abstract：:Male cosmetic patients represent a growing population of individuals who can substantially benefit from well-chosen esthetic interventions. Understanding some of the unique aspects of the male psyche can result in more effective recruitment of male cosmetic patients and aid the clinician in helping these patients to c...

journal_title：Dermatologic therapy

authors： Fried RG

更新日期：2007-11-01 00:00:00

abstract：:The highest efficacy of oral propranolol is for infantile hemangioma (IH) in the proliferative phase. Evaluation of the effectiveness of oral propranolol is less established when it is administered in late infancy following the proliferative phase. We aimed to assess the clinical outcomes of pediatric patients managed...

journal_title：Dermatologic therapy

authors： Kridin K,Pam N,Bergman R,Khamaysi Z

更新日期：2020-05-01 00:00:00

abstract：:For many years, drug therapies were not explicitly studied in the pediatric population. The lack of data forced clinicians to treat children using empiric therapy, often guessing at the treatment dose. In addition to the lack of dosing information, there was no evidence that a product would be safe and efficacious in ...

journal_title：Dermatologic therapy

authors： Mathis L,Rodriguez W

更新日期：2009-05-01 00:00:00

abstract：:The major therapeutic approaches (5-fluorouracil, imiquimod, vermilionectomy, and CO(2) Laser ablation) for actinic cheilitis are aimed at avoiding and preventing a malignant transformation into invasive squamous cell carcinoma via destruction/removal of the damaged epithelium. Recently, photodynamic therapy (PDT) has...

journal_title：Dermatologic therapy

authors： Rossi R,Assad GB,Buggiani G,Lotti T

更新日期：2008-09-01 00:00:00

abstract：:Onychomycosis is an important medical disorder affecting both health and quality of life of patients. This study was done to compare the efficacy of CO2 laser in combination with topical tioconazole versus CO2 laser only versus topical tioconazole alone in onychomycosis. A total of 120 patients with onychomycosis were...

journal_title：Dermatologic therapy

authors： Zaki AM,Abdo HM,Ebadah MA,Ibrahim SM

更新日期：2020-01-01 00:00:00

abstract：:Pemphigus encompasses a group of chronic autoimmune blistering diseases of the skin and/or mucosa. Rituximab (RTX) has shown promising efficacy for the treatment of pemphigus in the past decade. Considering potential cardiac side effects, this study was conducted to assess the effects of RTX on electrocardiogram (ECG)...

journal_title：Dermatologic therapy

authors： Aidi S,Daneshpazhooh M,Eslami M,Azizpour A,Toosi R,Mollazadeh R

更新日期：2020-11-01 00:00:00

abstract：:Melasma is a human melanogenesis dysfunction that results in localized, chronic acquired hyperpigmentation of the skin. It has a significant impact on appearance, causing psychosocial and emotional distress, and reducing the quality of life of the affected patients. Tranexamic acid (TA) is a plasmin inhibitor used to ...

journal_title：Dermatologic therapy

authors： Taraz M,Niknam S,Ehsani AH

更新日期：2017-05-01 00:00:00

abstract：:Pemphigus vulgaris (PV), an autoimmune blistering disease is treated with immunosuppressive medications. As the immunosuppressive effect of rituximab, the first-line therapy of PV, lasts more than 6 months, many concerns have raised due to the ongoing novel coronavirus disease (COVID-19) pandemic. With this background...

journal_title：Dermatologic therapy

authors： Beyzaee AM,Rahmatpour Rokni G,Patil A,Goldust M

更新日期：2020-10-13 00:00:00

abstract：:Bexarotene is a retinoid that specifically binds retinoid X receptors and has numerous effects on cellular growth and differentiation. It is approved for the treatment of cutaneous T cell lymphoma both topically and systemically. Adverse effects include hyperlipidemia, central hypothyroidism, and neutropenia with bexa...

journal_title：Dermatologic therapy

authors： Schadt CR

更新日期：2013-09-01 00:00:00

abstract：:Leishmaniasis is an infectious disease caused by parasitic flagellates of the genus Leishmania. The authors present a case of 44-year-old man with Crohn's disease treated successfully with infliximab. This case report shows rare visceral leishmaniasis with cutaneous symptoms in an immunocompromised patient. Skin manif...

journal_title：Dermatologic therapy

authors： Juzlova K,Votrubova J,Kacerovska D,Lukas M,Bortlik M,Rohacova H,Nohynkova E,Vojackova N,Fialova J,Hercogova J

更新日期：2014-05-01 00:00:00

abstract：:Photodermatoses can be classified into five general categories: 1) idiopathic photodermatoses, including polymorphic light eruption (PMLE), actinic prurigo, hyroa vacciniforme, chronic actinic dermatitis, and solar urticaria; 2) photodermatoses which are secondary to exogenous agents, including phototoxic and photoall...

journal_title：Dermatologic therapy

authors： Yashar SS,Lim HW

更新日期：2003-01-01 00:00:00

abstract：:Acrodermatitis continua of Hallopeau (ACH) is a chronic, inflammatory, and relapsing disorder characterized by the progressive destruction of fingernails and toenails. This condition is rare, difficult to treat, and often misdiagnosed. Several antipsoriatic treatments have been used, without any therapeutic guideline ...

journal_title：Dermatologic therapy

authors： Lanna C,Cesaroni GM,Mazzilli S,Lozzi F,Palumbo V,Diluvio L,Bianchi L,Campione E

更新日期：2019-07-01 00:00:00

abstract：:For effective treatment of vitiligo, it is as important to arrest the progression of the disease, as it is to induce repigmentation. Epidermal oxidative stress has been documented in vitiligo patients, and there is much support for a free-radical-mediated damage as an initial pathogenic event in melanocyte degeneratio...

journal_title：Dermatologic therapy

authors： Parsad D,Kanwar A

更新日期：2010-05-01 00:00:00