Abstract:
:In bacterial polypeptide synthesis aminoacyl-tRNA (aa-tRNA) bound to elongation factor Tu (EF-Tu) and GTP is part of a crucial intermediate ribonucleoprotein complex involved in the decoding of messenger RNA. The conformation and topology as well as the affinity of the macromolecules in this ternary aa-tRNA X EF-Tu X GTP complex are of fundamental importance for the nature of the interaction of the complex with the ribosome. The structural elements of aa-tRNA required for interaction with EF-Tu and GTP and the resulting functional implications are presented here.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Faulhammer HG,Joshi RLdoi
10.1016/0014-5793(87)80664-6subject
Has Abstractpub_date
1987-06-15 00:00:00pages
203-11issue
2eissn
0014-5793issn
1873-3468pii
0014-5793(87)80664-6journal_volume
217pub_type
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