Abstract:
:Human hepatocellular carcinoma cells (Hep G2) were shown to secrete apo A-I as a proprotein . No apo A-I synthesis could be detected with endothelial cells from human umbilical cord veins. Conversion of proapo A-I into apo A-I is a slow (of the order of hours) process, mediated by a Ca2+/Mg2+-dependent enzyme which is present on the surface of plasma lipoprotein particles, endothelial cells and Hep G2 cells, and is probably synthesized by Hep G2 cells.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Kooistra T,van Hinsbergh V,Havekes L,Kempen HJdoi
10.1016/0014-5793(84)81379-4subject
Has Abstractpub_date
1984-05-07 00:00:00pages
109-13issue
1eissn
0014-5793issn
1873-3468journal_volume
170pub_type
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