Effects of locus coeruleus activation and inactivation on hippocampal formation theta rhythm in anesthetized rats.

abstract：:Massively obese males often show symptoms of hypogonadism, but the mechanism for this is unclear. Increased endogenous opioid inhibition of the hypothalamic GnRH pulse generator resulting in insufficient stimulation of the pituitary gonadotroph has been proposed as a possible mechanism. If this hypothesis is correct, ...

journal_title：Brain research bulletin

authors： Blank DM,Clark RV,Heymsfield SB,Rudman DR,Blank MS

更新日期：1994-01-01 00:00:00

abstract：:Nagase genetically analbuminemic rats (NAR) were run to fatigue. Administration of branched chain amino acids (BCAA) before exhaustive exercise, resulted in a post-fatigue decreased tryptophan uptake (-22%, p < 0.05) and 5-hydroxytryptophan (5-HTP) uptake (-29%, p < 0.01) into the synaptosomes isolated from the striat...

journal_title：Brain research bulletin

authors： Yamamoto T,Newsholme EA

更新日期：2000-05-01 00:00:00

abstract：:Postpartum female rats exhibit a suppression of anxiety-related behaviors when compared to diestrous virgin females, pregnant females, and males. This blunted anxiety promotes optimal maternal care and involves elevated GABA neurotransmission, possibly including greater density of GABA(A) and benzodiazepine receptors ...

journal_title：Brain research bulletin

authors： Miller SM,Lonstein JS

更新日期：2011-08-10 00:00:00

abstract：:Histopathological effects of the artemisinin antimalarial, beta-arteether, were evaluated in rats. Arteether (3.125-12.5 mg/kg/day, IM, in sesame oil) was administered for 7 consecutive days. Seven days following the last injection, histological evaluation of the brainstem was performed. Rats treated with 12.5 mg/kg s...

journal_title：Brain research bulletin

authors： Genovese RF,Newman DB,Li Q,Peggins JO,Brewer TG

更新日期：1998-01-01 00:00:00

abstract：:When applied by iontophoresis onto single sympathetic preganglionic neurones in the intermediolateral nucleus of segments T1-T3 in the cat, oxytocin and vasopressin each had an excitatory effect. This effect consisted of a prolonged (30-300 sec) after-discharge following termination of application. These results indic...

journal_title：Brain research bulletin

authors： Backman SB,Henry JL

更新日期：1984-11-01 00:00:00

abstract：:In a search for morphofunctional relationships in the head of the caudate nucleus (CN), we recorded extracellular unit activity in intact cats and in cats that had received bilateral injections of 6-OHDA into the substantia nigra (SN) 30 days previously. Only units firing spontaneously and continuously for 2 min were ...

journal_title：Brain research bulletin

authors： Gasteiger EL,Roig JA,Zarco-Coronado I,Estrada Y,Vargas E,Brust-Carmona H

更新日期：1984-01-01 00:00:00

abstract：:Here we have investigated whether differences in levels of dopamine D1-like, D2-like receptors, dopamine D3 receptors, and dopamine transporter could be related to behaviors such as immobility response and locomotion between Wistar rats and Sprague-Dawley rats. The levels of the dopamine receptors and transporter were...

journal_title：Brain research bulletin

authors： Zamudio S,Fregoso T,Miranda A,De La Cruz F,Flores G

更新日期：2005-04-30 00:00:00

abstract：:Rats implanted with electrodes for polygraphic recording were deprived of REM sleep for 24 hr. Following REM sleep deprivation animals were injected with quipazine maleate (7.5 mg/kg IP) and were polygraphically recorded for 48 hr. The results show that quipazine reduces REM sleep rebound and that it has a biphasic ef...

journal_title：Brain research bulletin

authors： Zak R,Radulovacki M

更新日期：1982-03-01 00:00:00

abstract：:Neonatal rats, when spinalized on the fourteenth postnatal day, showed minimal recovery of function in their hindlimbs. Bridging the cut spinal cord with E16 fetal spinal cord tissue did not improve functional recovery. Bridging, plus treatment with GM1 ganglioside, caused a significant (p less than 0.05) improvement ...

journal_title：Brain research bulletin

authors： Commissiong JW,Sauve Y,Csonka K,Karoum F,Toffano G

更新日期：1991-07-01 00:00:00

abstract：:miR-196a is located in the posterior trunk and plays a role in limb development. Here we show that miR-196a is able to induce eye anomaly in Xenopus laevis. Microinjection of synthetic miRNA precursor molecule for mammalian miR-196a into Xenopus embryo is sufficient for miR-196a overexpression during early development...

journal_title：Brain research bulletin

authors： Qiu R,Liu Y,Wu JY,Liu K,Mo W,He R

更新日期：2009-04-06 00:00:00

abstract：:Serotonin 5-HT1A receptors belong to the superfamily of G-protein-coupled receptors. Receptor activation of G-proteins can be determined by agonist-stimulated [35S]GTPgammaS binding in the presence of excess GDP, and in vitro autoradiographic adaptation of this technique allows visualization of receptor-activated G-pr...

journal_title：Brain research bulletin

authors： Sim LJ,Xiao R,Childers SR

更新日期：1997-01-01 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:The assumption was made that investigatory behaviors (i.e., ano-genital and general body sniffing) of a female conspecific by a mature male rat, has positive hedonic characteristics. Because reduced interest in pleasurable events (i.e., anhedonia) is diagnostically related to depressive behavior, the hypothesis was ad...

journal_title：Brain research bulletin

authors： Paré WP

更新日期：2000-12-01 00:00:00

abstract：:In previous studies we have demonstrated that spinal motoneurons in the adult cat can regenerate CNS-type axons through CNS scar tissue into denervated ventral roots. This scar tissue, which appears to support and sustain the growth of injured CNS axons, has been shown to have a persistent defect in the blood-brain ba...

journal_title：Brain research bulletin

authors： Risling M,Fried K,Linda H,Carlstedt T,Cullheim S

更新日期：1993-01-01 00:00:00

abstract：:Although increasing evidence indicates that psychiatric symptoms are crucial characteristic of the early stage of Parkinson's disease (PD) and precede motor impairments, the neuronal firing activity of the basolateral nucleus of the amygdala (BLA) in the psychiatric symptom of PD and the involved mechanism are still u...

journal_title：Brain research bulletin

authors： Chen L,Liu J,Zhang QJ,Feng JJ,Gui ZH,Ali U,Wang Y,Fan LL,Hou C,Wang T

更新日期：2011-07-15 00:00:00

abstract：:Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in people over 60 years of age in the US and many other developed countries. Increasingly sophisticated methods for the diagnosis and treatment of macular degeneration are not effective for the majority of patients in whom late stage...

journal_title：Brain research bulletin

authors： Rowe-Rendleman C,Glickman RD

更新日期：2004-02-15 00:00:00

abstract：:Previous work in our laboratory suggests that the indirect stimulation of prolactin gene transcription observed in male rats between 3 and 6 h following estrogen injection results from an inhibition of dopamine release from the tuberoinfundibular dopaminergic neurons. To evaluate further the role of dopamine in the re...

journal_title：Brain research bulletin

authors： Shaw-Bruha CM,Happe HK,Murrin LC,Rodriguez-Sierra JF,Shull JD

更新日期：1996-01-01 00:00:00

abstract：:Cocaine is a major stimulant drug which can have rewarding and locomotor activating effects. It is used by non-addicts to enhance concentration and performance in a work or social setting. It was suggested that cocaine may amplify the impact of mood and sensory stimulation on behaviour. Here we tested whether cocaine ...

journal_title：Brain research bulletin

authors： Pum ME,Rubio AR,Carey RJ,Silva MA,Müller CP

更新日期：2011-02-28 00:00:00

abstract：:We celebrate in 1998 the centenary of the discovery of the Golgi apparatus. Neurones have played a special role in the history of this cell organelle, primarily because the endocellular apparatus was discovered in nerve cells by Camillo Golgi when he was studying the cerebellum of an owl. In the following years, the a...

journal_title：Brain research bulletin

authors： Dröscher A

更新日期：1998-10-01 00:00:00

abstract：:Image analysis methods are being developed for measuring the density and distribution of perivascular noradrenergic nerves and their varicosities, demonstrated by fluorescence histochemistry. Image analysis is recommended in comparison with other methods for the quantitation of fluorescence, because image resolution i...

journal_title：Brain research bulletin

authors： Cowen T,Burnstock G

更新日期：1982-07-01 00:00:00

abstract：:Urethane is often used as a central anaesthetic in neurophysiological studies of drug effects. In this experiment, the effect of morphine on cortical EEG and single units of hippocampus and medial thalamus were compared in urethane-anaesthetized and paralyzed-awake rats. In each case, there was evidence of a morphine-...

journal_title：Brain research bulletin

authors： Linseman MA

更新日期：1980-03-01 00:00:00

abstract：:Chemical preconditioning using the mitochondrial toxin, 3-nitropropionic acid (3-NP) has been reported to induce neuroprotection against subsequent global ischemia. To investigate the underlying mechanisms, Mongolian gerbils were pretreated with either vehicle or 3-NP at the dose of 3 or 10 mg/kg, intraperitoneal, 3 d...

journal_title：Brain research bulletin

authors： Garnier P,Bertrand N,Demougeot C,Prigent-Tessier A,Marie C,Beley A

更新日期：2002-05-01 00:00:00

abstract：:Somatostatin immunoreactive (SOM-I) perikarya were first observed in the ventral horn at E12, in the presumptive intermediate gray area at E14, and in the alar plate of the rostral spinal cord at E14. In general, after their initial appearance, their density increased and then decreased during development. A moderate ...

journal_title：Brain research bulletin

authors： Ho RH

更新日期：1988-07-01 00:00:00

abstract：:Delayed visual maturation (DVM) is characterised by visual unresponsiveness in early infancy, which subsequently improves spontaneously to normal levels. We studied the optokinetic response and recorded pattern reversal VEPs in six infants with DVM (aged 2-4 months) when they were at the stage of complete visual unres...

journal_title：Brain research bulletin

authors： Harris CM,Kriss A,Shawkat F,Taylor D,Russell-Eggitt I

更新日期：1996-01-01 00:00:00

abstract：:Electroretinographic evoked potentials (ERGs) were recorded in dark adapted crayfish by the application of pulses of light (0.09 Cd/ft2) presented every 2.5 min. Heterolateral illumination (HI) for sixty min (0.06-0.3 Cd/ft2) induced up to 50% decrease in ERG after a latency of 12-25 min. ERG depression was proportion...

journal_title：Brain research bulletin

authors： Barrera-Mera B,Abasta EM

更新日期：1978-03-01 00:00:00

abstract：:Methylphenidate (MPD), commonly known as Ritalin, is the most frequently prescribed drug to treat children and adults with attention deficit hyperactivity disorder (ADHD). Adolescence is a period of development involving numerous neuroplasticities throughout the central nervous system (CNS). Exposure to a psychostimul...

journal_title：Brain research bulletin

authors： Yang PB,Swann AC,Dafny N

更新日期：2006-12-11 00:00:00

abstract：:The localization of CGRP mRNA in neurons of the rat brain and spinal cord was assessed by in situ hybridization histochemistry (ISH) using a radiolabeled synthetic 57-mer oligodeoxynucleotide probe complementary to the rat prepro CGRP mRNA. Results were compared with previously published findings of CGRP-immunoreactiv...

journal_title：Brain research bulletin

authors： Kresse A,Jacobowitz DM,Skofitsch G

更新日期：1995-01-01 00:00:00

abstract：:Previous research has demonstrated that while primary visual cortex lesions in rats will disrupt performance of a learned brightness discrimination, the neural traces associated with this discrimination are spared. Moreover, the spared neural traces may, in certain instances, influence the postoperative reinstatement ...

journal_title：Brain research bulletin

authors： Levere TE,Davis N,Fontaine CW

更新日期：1978-01-01 00:00:00

abstract：:This study investigated the effects of neonatal unilateral adrenalectomy on the serotonin- (5-HT) and thyrotropin-releasing hormone-like immunoreactivities (TRH-LI) in the intermediolateral cell column (IML) of the rat spinal cord where the sympathetic preganglionic neurons innervating the adrenal medulla are located....

journal_title：Brain research bulletin

authors： Poulat P,Marlier L,Rajaofetra N,Privat A

更新日期：1993-01-01 00:00:00

abstract：:The antidepressant desipramine has been shown to decrease synaptic membrane concentrations of the norepinephrine re-uptake transporter (NET) in vivo and in vitro, on both an acute and a chronic basis. The possible contribution of decreased NET synthesis to the chronic downregulation of the NETs has not been definitive...

journal_title：Brain research bulletin

authors： Zavosh A,Schaefer J,Ferrel A,Figlewicz DP

更新日期：1999-07-01 00:00:00