Abstract:
:Delayed visual maturation (DVM) is characterised by visual unresponsiveness in early infancy, which subsequently improves spontaneously to normal levels. We studied the optokinetic response and recorded pattern reversal VEPs in six infants with DVM (aged 2-4 months) when they were at the stage of complete visual unresponsiveness. Although no saccades or visual tracking with the eyes or head could be elicited to visual objects, a normal full-field rapid buildup OKN response occurred when viewing biocularly or during monocular stimulation in the temporo-nasal direction of the viewing eye. Almost no monocular OKN could be elicited in the naso-temporal direction, which was significantly poorer than normal age-matched infants. No OKN quick phases were missed, and there were no other signs of "ocular motor apraxia." VEPs were normal in amplitude and latency for age. It appears, therefore, that infants with DVM are delayed in orienting to local regions of the visual field, but can respond to full-field motion. The presence of normal OKN quick-phases and slow-phases suggests normal brain stem function, and the presence of normal pattern VEPs suggests a normal retino-geniculo-striate pathway. These oculomotor and electrophysiological findings suggest delayed development of extra-striate cortical structures, possibly involving either an abnormality in figure-ground segregation or in attentional pathways.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Harris CM,Kriss A,Shawkat F,Taylor D,Russell-Eggitt Idoi
10.1016/0361-9230(96)00128-1subject
Has Abstractpub_date
1996-01-01 00:00:00pages
365-9issue
5-6eissn
0361-9230issn
1873-2747pii
0361-9230(96)00128-1journal_volume
40pub_type
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journal_title:Brain research bulletin
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:1976-01-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:2000-08-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:2012-02-10 00:00:00
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更新日期:1992-04-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(92)90045-y
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:1982-07-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2005.01.007
更新日期:2005-04-15 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:2009-06-30 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(87)90139-0
更新日期:1987-05-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:1982-07-01 00:00:00
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pub_type: 杂志文章
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