In vitro autoradiographic localization of 5-HT1A receptor-activated G-proteins in the rat brain.

abstract：:Rearing preweanling rat pups away from their mothers by feeding through chronic intragastric cannulas has been shown to result in alterations in the growth of specific organs. In the present study, artificially reared (AR) rats and their normally reared (NR) siblings were sacrificed at various ages during this procedu...

journal_title：Brain research bulletin

authors： Diaz J,Moore E,Petracca F,Stamper C

更新日期：1983-12-01 00:00:00

abstract：:Hypothalamic-pituitary-adrenal (HPA) responses to single-dose nicotine (NIC) are sexually diergic: Female rats have higher adrenocorticotropic hormone (ACTH) and corticosterone (CORT) responses than do males. In the present study we determined HPA responses in male and female rats following single doses of NIC, a sing...

journal_title：Brain research bulletin

authors： Gentile NE,Andrekanic JD,Karwoski TE,Czambel RK,Rubin RT,Rhodes ME

更新日期：2011-05-30 00:00:00

abstract：:In experimental studies on peripheral nerve repair, the possibility to objectively compare original and post-operative innervation is of decisive importance for the selection of the proper nerve-reconstruction strategy. Herewith we report serious drawbacks encountered with the standard method of pre- and post-operativ...

journal_title：Brain research bulletin

authors： Popratiloff AS,Neiss WF,Skouras E,Streppel M,Guntinas-Lichius O,Angelov DN

更新日期：2001-01-01 00:00:00

abstract：:In the frog Rana esculenta the left dorsal habenula includes a lateral and a medial component, whereas the right dorsal habenula is only represented by one nucleus. The efferents of the habenular nuclei to the interpeduncular nucleus were herein investigated with the retrograde horseradish peroxidase tracing. Injectio...

journal_title：Brain research bulletin

authors： Gugliemotti V,Fiorino L

更新日期：1998-01-01 00:00:00

abstract：:Histopathological effects of the artemisinin antimalarial, beta-arteether, were evaluated in rats. Arteether (3.125-12.5 mg/kg/day, IM, in sesame oil) was administered for 7 consecutive days. Seven days following the last injection, histological evaluation of the brainstem was performed. Rats treated with 12.5 mg/kg s...

journal_title：Brain research bulletin

authors： Genovese RF,Newman DB,Li Q,Peggins JO,Brewer TG

更新日期：1998-01-01 00:00:00

abstract：:Since the groundbreaking work of Ramon y Cajal, the cerebellar Purkinje cell has always represented an ideal model for studying the organization, development and function of synaptic circuits. Purkinje cells receive distinct types of glutamatergic and GABAergic synapses, each characterized by exquisite sub-cellular an...

journal_title：Brain research bulletin

authors： Sassoè-Pognetto M,Patrizi A

更新日期：2017-03-01 00:00:00

abstract：:To clarify the role of febrile temperatures on the immune system, rats were immunized with sheep erythrocytes and their core temperature was then changed by continuously cooling or heating the preoptic area for five days. Core temperatures of up to 2 degrees C above or below normal were associated with a high titre of...

journal_title：Brain research bulletin

authors： Brandt S,Banet M

更新日期：1984-08-01 00:00:00

abstract：:Mechanisms underlying shock-induced conditioned fear - a paradigm frequently used to model posttraumatic stress disorder, PTSD - are usually studied shortly after shocks. Some of the brain regions relevant to conditioned fear were activated in all the c-Fos studies published so far, but the overlap between the activat...

journal_title：Brain research bulletin

authors： Tulogdi A,Sörös P,Tóth M,Nagy R,Biró L,Aliczki M,Klausz B,Mikics E,Haller J

更新日期：2012-07-01 00:00:00

abstract：:Chronic pain and depressive disorders have been estimated to co-occur in up to 80% of patients and traditional antidepressants and analgesics have shown limited clinical efficacy. α- (phenylselanyl) acetophenone (PSAP) is an organic selenium compound which has already demonstrated antioxidant, antidepressant and antin...

journal_title：Brain research bulletin

authors： Sousa FSS,Birmann PT,Baldinotti R,Fronza MG,Balaguez R,Alves D,Brüning CA,Savegnago L

更新日期：2018-09-01 00:00:00

abstract：:In post-natal kittens which were given injections of HRP in the suprasylvian gyrus (polysensory cortex), the cortico-cortical connections were studied qualitatively and quantitatively. These connections originate essentially from cortical cells localized in cortices of the upper part of the hemisphere. They are formed...

journal_title：Brain research bulletin

authors： Ben Hamida C

更新日期：1985-11-01 00:00:00

abstract：:The spontaneous activity of hippocampal and denate units was investigated in acute and chronic experiments on adult rats. Spontaneous unitary discharges from both regions were measured before and after brief tetanic stimulation of the entorhinal cortex. An increase in the frequency of spontaneous unit activity was obt...

journal_title：Brain research bulletin

authors： Deadwyler SA,Gribkoff V,Cotman C,Lynch G

更新日期：1976-01-01 00:00:00

abstract：:Diminished sensitivity to kainic acid (KA) lesioning action is present in the hippocampus of the lactating dam. Given that KA can alter blood-brain barrier (BBB) permeability, we investigated whether lactation would protect BBB permeability after treatment with this neurotoxin. Adult virgin or lactating (13-15 days pp...

journal_title：Brain research bulletin

authors： Solís CD,Morales T

更新日期：2019-01-01 00:00:00

abstract：:Electrical stimulation has been shown to have neuroprotective effects on ganglion cells and photoreceptors in axotomized and dystrophic retinas from Royal College of Surgeons (RCS) rats. This study determined whether electrical stimulation also has a neuroprotective effect on cells in the inner nuclear layer (INL) of ...

journal_title：Brain research bulletin

authors： Schmid H,Herrmann T,Kohler K,Stett A

更新日期：2009-04-06 00:00:00

abstract：:The involvement of alpha-amino-3-hydroxy-5-methylizoxazole-4-propionic acid (AMPA) receptors in induction of long-term potentiation (LTP) was examined in rat hippocampal slice preparation. Using conventional extracellular recording, excitatory postsynaptic potentials (EPSPs) and population action potentials (PSs), evo...

journal_title：Brain research bulletin

authors： Kapus G,Székely JI,Durand J,Ruiz A,Tarnawa I

更新日期：2000-08-01 00:00:00

abstract：:Under standard laboratory conditions rats given access to three separate macronutrient sources compose a diet yielding 31% of their total daily calories as protein, 34% as carbohydrate, and 34% as fat. This selection pattern is dramatically altered with restored access following a 48 h fast. During the first hour of r...

journal_title：Brain research bulletin

authors： Bernardini J,Kamara K,Castonguay TW

更新日期：1993-01-01 00:00:00

abstract：:Rats self-administered cocaine or received saline during 3 daily 5 h sessions and were euthanized 1 h after the final session. Quantitative in situ hybridization revealed that cocaine self-administration increased levels of preprodynorphin, but not preproenkephalin, c-fos, or zif/268 mRNAs in a patchy pattern in the d...

journal_title：Brain research bulletin

authors： Daunais JB,Roberts DC,McGinty JF

更新日期：1995-01-01 00:00:00

abstract：:In alpha-chloralose-anesthetized Sprague-Dawley (SD) rats with unilateral nucleus tractus solitarius (NTS) lesions, injection of the alpha(1)-adrenergic receptor agonist phenylephrine into the contralateral NTS dose-dependently increased arterial pressure (AP). Bunazosin (0.1 nmol) or prazosin (0.36 nmol), an alpha(1)...

journal_title：Brain research bulletin

authors： Tsukamoto K,Ito S,Katsunuma N,Hiratsuka M,Masubuchi Y,Kanai T,Kawabe T,Yajima Y,Kanmatsuse K

更新日期：2002-08-15 00:00:00

abstract：:The goal of this study was to determine if the dorsal noradrenergic bundle (DNAB) plays an essential role in mediating increased plasma renin activity (PRA) and hypothalamic activation, as indicated by increased Fos expression, in response to a small volume blood loss in unanesthetized animals. Male Sprague-Dawley rat...

journal_title：Brain research bulletin

authors： Jaworski RL,Blair ML

更新日期：2004-07-15 00:00:00

abstract：:Rodent models for the study of neurogenic bladder dysfunction after spinal cord injury (SCI) are difficult to standardize, particularly when evaluating the specific contribution of the SCI to end-organ function. The purpose of this study was to evaluate the degree of bladder dysfunction associated with a highly reprod...

journal_title：Brain research bulletin

authors： Munoz A

更新日期：2017-05-01 00:00:00

abstract：:Administering increasing dosages of 5alpha-dihydrotestosterone propionate (DHTP) (0, 40, or 80 microgram/100 g in oil daily) to ovariectomized female rats treated concurrently with estradiol benzoate (EB) (1 microgram/100 g in oil daily) caused significant, equivalent reduction in lordotic responsiveness in rats maint...

journal_title：Brain research bulletin

authors： Menniti FS,Erskine MS,Baum MJ

更新日期：1981-07-01 00:00:00

abstract：:Inhibition of glycolysis and fatty acid oxidation by combined treatment with 2-deoxyglucose (2DG) and methyl palmoxirate, or inhibition of glycolysis and lipolysis by combined treatment with 2DG and nicotonic acid synergistically increased food intake in rats. Methyl palmoxirate treatment alone increased food intake i...

journal_title：Brain research bulletin

authors： Friedman MI,Tordoff MG,Ramirez I

更新日期：1986-12-01 00:00:00

abstract：:Thyroid hormones are essential for neonatal brain development. It is well established that absence of thyroid hormones during critical periods of development can alter sensory functions such as visual and auditory processing, but there are few studies on rat somatosensory system development at mild, long-term, and irr...

journal_title：Brain research bulletin

authors： Afarinesh MR,Shafiei F,Sabzalizadeh M,Haghpanah T,Taheri M,Parsania S,Golshan F,Sheibani V

更新日期：2020-02-01 00:00:00

abstract：:Cultures of endothelial cells (EC) derived from human (autopsy) and canine brain microvessels were characterized with respect to growth, morphology, and biochemical features. The endothelial nature of these cells was confirmed by analyses of angiotensin-converting enzyme activity, Factor VIII-related antigen, and ultr...

journal_title：Brain research bulletin

authors： Gerhart DZ,Broderius MA,Drewes LR

更新日期：1988-11-01 00:00:00

abstract：:We have studied the effects of 14-methoxymetopon (HS 198), a potent opioid agonist, on the responses to the tail electric stimulation test and plus-maze activity of adult male rats. The prototype mu agonist morphine was used as the drug of reference. Besides we addressed the effects of HS 198 on the serum corticostero...

journal_title：Brain research bulletin

authors： Urigüen L,Fernández B,Romero EM,De Pedro N,Delgado MJ,Guaza C,Schmidhammer H,Viveros MP

更新日期：2002-03-15 00:00:00

abstract：:The effects of electrical stimulation of the "mesencephalic locomotor region" and adjacent dorsolateral tegmentum were assessed and compared in the same rats in freely moving conditions or when lightly anesthetized and suspended over a moving treadmill. In freely moving conditions, electrical brain stimulation (EBS) o...

journal_title：Brain research bulletin

authors： Depoortere R,Di Scala G,Sandner G

更新日期：1990-11-01 00:00:00

abstract：:The relationship between the "passions" (emotions or feelings) and psychopathology has been a constant throughout the history of medicine. In this context, melancholy was considered a perversion of the soul (corruption of the passions). One of the most influential authors on this subject was René Descartes, who discus...

journal_title：Brain research bulletin

authors： López-Muñoz F,Rubio G,Molina JD,Alamo C

更新日期：2011-04-25 00:00:00

abstract：:miR-196a is located in the posterior trunk and plays a role in limb development. Here we show that miR-196a is able to induce eye anomaly in Xenopus laevis. Microinjection of synthetic miRNA precursor molecule for mammalian miR-196a into Xenopus embryo is sufficient for miR-196a overexpression during early development...

journal_title：Brain research bulletin

authors： Qiu R,Liu Y,Wu JY,Liu K,Mo W,He R

更新日期：2009-04-06 00:00:00

abstract：:Space motion sickness (SMS) and spatial orientation and motion perception disturbances occur in 70-80% of astronauts. People select "rest frames" to create the subjective sense of spatial orientation. In microgravity, the astronaut's rest frame may be based on visual scene polarity cues and on the internal head and bo...

journal_title：Brain research bulletin

authors： Harm DL,Parker DE,Reschke MF,Skinner NC

更新日期：1998-11-15 00:00:00

abstract：:Fibroblast growth factor 9 (FGF9) is a member of the fibroblast growth factor family and is widely expressed in the central nervous system (CNS). However, it is not clear how the working mechanism of FGF9 is involved in cerebellar development. To address this question, we deleted the Fgf9 gene specifically in GABAergi...

journal_title：Brain research bulletin

authors： Guo M,Chen H,Duan W,Li Z,Li Y,Ma Y,Xu X,Yi L,Bi Y,Liu Y,Zhang J,Li C

更新日期：2020-01-01 00:00:00

abstract：:The aim of this magnetic resonance imaging study was to find a geometrical characterization of the deeper part of the corpus callosum. Its shape was studied in 12 middle-aged persons free of white matter pathology. Profiles of curvatures were measured showing that this surface was close to a minimal one, especially at...

journal_title：Brain research bulletin

authors： Stievenart JL,Iba-Zizen MT,Tourbah A,Lopez A,Thibierge M,Abanou A,Cabanis EA

更新日期：1997-01-01 00:00:00