Effects of D-glucose anomers on sweetness taste and insulin release in man.

abstract：:Calcium channels affect many neuronal functions, including membrane electrical excitability, synaptic transmission, cellular homeostasis, gene transcription, growth, and development. We used recently developed methods for serum-free culture of adult and embryonic rat neurons to study the development of voltage-sensiti...

journal_title：Brain research bulletin

authors： Collings MA,Brewer GJ,Evans MS

更新日期：1999-01-01 00:00:00

abstract：:Theories pertaining to the "why" of motion sickness are in short supply relative to those detailing the "how." Considering the profoundly disturbing and dysfunctional symptoms of motion sickness, it is difficult to conceive of why this condition is so strongly biologically based in humans and most other mammalian and ...

journal_title：Brain research bulletin

authors： Bowins B

更新日期：2010-01-15 00:00:00

abstract：:Wnt signaling plays an important role in the adult brain function and its dysregulation has been implicated in some neurodegenerative pathways. Despite the functional role of the Wnt signaling in adult neural circuits, there is currently no evidence regarding the relationships between exogenously Wnt signaling activat...

journal_title：Brain research bulletin

authors： Ortiz-Matamoros A,Arias C

更新日期：2018-05-01 00:00:00

abstract：:Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valua...

journal_title：Brain research bulletin

authors： Arendt T,Stieler JT,Holzer M

更新日期：2016-09-01 00:00:00

abstract：:It has been demonstrated that MK-801 potentiates the effects of the non-selective muscarinic antagonist scopolamine on memory in rats. In this study, we investigated the role of the M1-muscarinic receptor in this interaction, by administering different doses of dicyclomine (DIC) and MK-801 in combination to male Wista...

journal_title：Brain research bulletin

authors： Monteiro Moreira K,Lima Ferreira T,Vecchio Fornari R,Perez Figueredo LZ,Menezes Oliveira MG

更新日期：2005-11-30 00:00:00

abstract：:A recent in vitro electrophysiological analysis combined with anatomical approach suggests that a potential disinhibitory mechanism involving somatostatin (SST), which is released by interneurons in the superficial dorsal horn, contributes to nociceptive transmission (Yasaka et al., 2010); however, whether this mechan...

journal_title：Brain research bulletin

authors： Takahashi M,Takeda M,Matsumoto S

更新日期：2014-01-01 00:00:00

abstract：:This paper reviews and provides new data on the relationship of the peptide content in rat dorsal root ganglion (DRG) neurons to a) the neurofilament content of the soma and b) the conduction velocities of the fibres. The latter involved intracellular recordings made in vitro followed by dye injection and immunocytoch...

journal_title：Brain research bulletin

authors： Lawson SN,Perry MJ,Prabhakar E,McCarthy PW

更新日期：1993-01-01 00:00:00

abstract：:Nogo, also known as Reticulon-4, is a protein that is specific to the central nervous system (CNS), and has been identified as an inhibitor of neurite outgrowth. Nogo-A is the largest member of the Nogo family and is responsible for inhibition of CNS regeneration. The structural information and biological functions of...

journal_title：Brain research bulletin

authors： Wang T,Xiong JQ,Ren XB,Sun W

更新日期：2012-04-10 00:00:00

abstract：:Locomotor activity was increased as a function of current intensity in a series of rats with chronic stimulating electrodes in the tegmental pedunculopontine nucleus. Single pulse stimulation of these same mesencephalic locomotor region (MLR) sites antidromically activated more than one-quarter of the neurons sampled ...

journal_title：Brain research bulletin

authors： Mogenson GJ,Wu M

更新日期：1986-03-01 00:00:00

abstract：:The present study aimed to investigate the effects of sleep deprivation (SD) on the dose-dependent stimulant effect of ethanol (ETOH) on the open-field behavior of female and male mice. Sleep-deprived (48 h, multiple platforms method) or home-cage control female mice were treated with saline (SAL) or 1.4, 1.8 or 2.2g/...

journal_title：Brain research bulletin

authors： Araujo NP,Andersen ML,Abílio VC,Gomes DC,Carvalho RC,Silva RH,Ribeiro Rde A,Tufik S,Frussa-Filho R

更新日期：2006-04-14 00:00:00

abstract：:Delayed visual maturation (DVM) is characterised by visual unresponsiveness in early infancy, which subsequently improves spontaneously to normal levels. We studied the optokinetic response and recorded pattern reversal VEPs in six infants with DVM (aged 2-4 months) when they were at the stage of complete visual unres...

journal_title：Brain research bulletin

authors： Harris CM,Kriss A,Shawkat F,Taylor D,Russell-Eggitt I

更新日期：1996-01-01 00:00:00

abstract：:The formalin test was used to measure the analgesia induced by restraint in male and female rats. Animals were restrained for 30 min or left undisturbed in their cage and then (1) killed immediately to collect blood for hormonal determinations; or (2) subcutaneously injected with formalin in the hind paw (or sham-inje...

journal_title：Brain research bulletin

authors： Aloisi AM,Ceccarelli I,Lupo C

更新日期：1998-09-01 00:00:00

abstract：:A high correlation between alcohol use and smoking has long been suggested by epidemiological data. We examined the potential behavioral interactions between ethanol and nicotine using ethanol-induced motor incoordination as the test response in mice. Effect of pretreatment of various doses of (-)-nicotine, (-)-cotini...

journal_title：Brain research bulletin

authors： Dar MS,Li C,Bowman ER

更新日期：1993-01-01 00:00:00

abstract：:Increases in expression of α4βδ GABAA receptors (GABARs), triggered by fluctuations in the neurosteroid THP (3α-OH-5α[β]-pregnan-20-one), are associated with changes in mood and cognition. We tested whether α4βδ trafficking and surface expression would be altered by in vitro exposure to flumazenil, a benzodiazepine li...

journal_title：Brain research bulletin

authors： Kuver A,Smith SS

更新日期：2016-01-01 00:00:00

abstract：:Studies were conducted to determine if norepinephrine activates both protein kinase C and the cyclic AMP-dependent protein kinase in cultured rat astrocytes using phosphoproteins as markers. Norepinephrine was found to decrease 32P incorporation into an acidic 80,000 M(R) protein. A similar response was observed with ...

journal_title：Brain research bulletin

authors： Mobley PL,Combs DL

更新日期：1992-09-01 00:00:00

abstract：:The vestibular nuclei and posterior cerebellum are the destination of vestibular primary afferents and the subject of this review. The vestibular nuclei include four major nuclei (medial, descending, superior and lateral). In addition, smaller vestibular nuclei include: Y-group, parasolitary nucleus, and nucleus inter...

journal_title：Brain research bulletin

authors： Barmack NH

更新日期：2003-06-15 00:00:00

abstract：:In animal models of Fetal Alcohol Syndrome, ethanol causes a number of changes in brain development, with many of these changes being very transient. This is especially true for the process of synaptogenesis in different brain areas. Our quantitative electron microscopic study of synaptogenesis in the molecular layer ...

journal_title：Brain research bulletin

authors： Hoff SF

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVE:To establish a link between tryptophan (a precursor for 5-hydroxytryptamine (5-HT) or serotonin, involved in sleep and fatigue) and post-operative fatigue after major surgery. BACKGROUND:There is a link between tryptophan (the precursor for the neurotransmitter 5-hydroxytryptamine), and its competitive bindi...

journal_title：Brain research bulletin

authors： McGuire J,Ross GL,Price H,Mortensen N,Evans J,Castell LM

更新日期：2003-04-15 00:00:00

abstract：:Methylphenidate (MPD) is a psychostimulant that enhances dopaminergic neurotransmission in the central nervous system by using mechanisms similar to cocaine and amphetamine. The mode of action of brain circuitry responsible for an animal's neuronal response to MPD is not fully understood. The nucleus accumbens (NAc) h...

journal_title：Brain research bulletin

authors： Chong SL,Claussen CM,Dafny N

更新日期：2012-03-10 00:00:00

abstract：:Long chain fatty acids (FA) and 2-monoacylglycerols (MG) are produced by lipoprotein lipase (LPL) from plasma triacylglycerols (TG) in capillaries of adipose tissue and transported to adipocytes for TG synthesis. It is widely proposed FA may be transported in cells by FA-binding protein. Mode of transport of MG has re...

journal_title：Brain research bulletin

authors： Scow RO,Blanchette-Mackie EJ

更新日期：1991-09-01 00:00:00

abstract：:The nucleus locus coeruleus (LC) has been implicated in the modulation of the spinal sensorimotor function. The aim of the present study was to examine the effect of electrical stimulation of the LC on sensorimotor function in the trigeminal system. The following two cases of sensorimotor behaviors mediated by the tri...

journal_title：Brain research bulletin

authors： Matsutani K,Tsuruoka M,Shinya A,Furuya R,Kawawa T

更新日期：2000-12-01 00:00:00

abstract：:A reduction in nerve conduction velocity and an increase in resistance to ischemic conduction failure are early signs of neural dysfunction in both diabetic patients and animal models of diabetes. The effect of Bimoclomol (BRLP-42), a drug under clinical development for the treatment of diabetic complications, on expe...

journal_title：Brain research bulletin

authors： Bíró K,Jednákovits A,Kukorelli T,Hegedüs E,Korányi L

更新日期：1997-01-01 00:00:00

abstract：:Inflammation and oxidative stress play an important role in cerebral ischemic pathogenesis. Polydatin has been proved to elicit numerous biological effects through its anti-inflammatory and anti-oxidant properties. However, little is known regard to the mechanism of polydatin's neuroprotection in ischemic stroke. We t...

journal_title：Brain research bulletin

authors： Ji H,Zhang X,Du Y,Liu H,Li S,Li L

更新日期：2012-01-04 00:00:00

abstract：:Simple tandem repeats represent more than 1% of the human genome: occasionally they exhibit intergenerational expansibility and are associated with neuromuscular diseases. In transgenic mice the same sequences elicit similar symptoms, but do not expand. We have searched for di-, tri-, and tetra-repeats in the publishe...

journal_title：Brain research bulletin

authors： Astolfi P,Bellizzi D,Losso MA,Sgaramella V

更新日期：2001-10-01 00:00:00

abstract：:A microdialysis probe, implanted in the posterior hypothalamus (PH) was used to examine changes of extracellular norepinephrine (NE) in freely moving rats from which mean arterial pressure (mAP) and heart rate (HR) were continuously monitored. Artificial cerebrospinal fluid (aCSF) was pumped through the probe and 10-m...

journal_title：Brain research bulletin

authors： Nakata T,Berard W,Kogosov E,Alexander N

更新日期：1990-10-01 00:00:00

abstract：:Mouse models that replicate facets of human neurological diseases are often used at the pre-clinical stage to better understand the underlying mechanisms of a disease and test the target engagement of potential therapeutic interventions. We recently characterized a mouse model of childhood-onset parkinsonism-dystonia,...

journal_title：Brain research bulletin

authors： Giraldo G,Janus C

更新日期：2021-01-01 00:00:00

abstract：:Previously we have shown that systemic injection of adenosine antagonists can significantly improve cold tolerance in both rats and humans. However, it is not clear whether systemic administration of adenosine antagonist acts peripherally or centrally at the thermoregulatory site. To resolve this, theophylline (nonsel...

journal_title：Brain research bulletin

authors： Wang XL,Lee TF,Wang LC

更新日期：1990-03-01 00:00:00

abstract：:Observation of people performing movements facilitates motor planning, execution and memory formation. Tempo, a crucial aspect involved in the execution of rhythmic movements, is normally perceived and learned through auditory channels. In this work, we ascertained whether: first, the frequency of self-paced finger mo...

journal_title：Brain research bulletin

authors： Bove M,Tacchino A,Pelosin E,Moisello C,Abbruzzese G,Ghilardi MF

更新日期：2009-09-28 00:00:00

abstract：:The effect of serotonin synthesis inhibitor, p-chlorophenylalanine (PCPA), on induction and maintenance of pseudopregnancy as indicated by deciduoma formation was examined in female rats. Animals were injected with 1 mg/kg b.wt. of reserpine on the day of metestrus, and silk thread was passed through and placed in the...

journal_title：Brain research bulletin

authors： Maekawa F,Yamanouchi K

更新日期：1996-01-01 00:00:00

abstract：:Depression is a state of low mood and aversion to activity, affecting a person's thoughts, behavior, motivation, feelings and sense of well-being, which is associated with dramatical gene expression changes in hippocampus. Rodents induced by chronic unpredictable mild stress (CUMS) demonstrate typical depression-like ...

journal_title：Brain research bulletin

authors： Tao Y,Xie Z,Shi J,Ou R,Wu H,Shi H,Huang F,Wu X

更新日期：2020-09-01 00:00:00