Abstract:
:This paper reviews and provides new data on the relationship of the peptide content in rat dorsal root ganglion (DRG) neurons to a) the neurofilament content of the soma and b) the conduction velocities of the fibres. The latter involved intracellular recordings made in vitro followed by dye injection and immunocytochemistry. Because neurofilament-poor DRG neurones have C-fibres, and A-fibre neurones are neurofilament rich, the soma neurofilament content of peptide containing neurones allowed predictions to be made about their conduction velocity ranges. Substance P-like immunoreactive (SP-LI) neurones were mostly small, neurofilament poor, but a few (15%) were neurofilament rich. From conduction velocity measurements, about half the C-fibre neurones studied and 10% of A delta-neurones but no A alpha/beta-neurones showed SP-LI. CGRP-LI neurones were also mainly neurofilament poor neurones, but 32% were neurofilament rich, including small, medium, and large neurones. Fibres of CGRP-LI neurones conducted in the C, A delta or A alpha/beta ranges. Neurones with somatostatin-LI (SOM-LI) were all neurofilament poor; preliminary data is consistent with SOM-LI neurones having C-fibres.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Lawson SN,Perry MJ,Prabhakar E,McCarthy PWdoi
10.1016/0361-9230(93)90250-fsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
239-43issue
3-4eissn
0361-9230issn
1873-2747pii
0361-9230(93)90250-Fjournal_volume
30pub_type
杂志文章abstract::Studies have indicated that glutamate receptor subunit 3 peptide B antibodies (GluR3B Ab's) by directing against a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid subtype glutamate receptors (AMPARs) subunit 3 (GluR3B) was involved in the hippocampal neuron damage in the pathogenesis of epilepsy. Glutamate accumula...
journal_title:Brain research bulletin
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journal_title:Brain research bulletin
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journal_title:Brain research bulletin
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journal_title:Brain research bulletin
pub_type: 杂志文章
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journal_title:Brain research bulletin
pub_type: 杂志文章
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journal_title:Brain research bulletin
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更新日期:1983-07-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
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更新日期:1997-01-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(87)90063-3
更新日期:1987-12-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:2002-06-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:1990-06-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(92)90088-f
更新日期:1992-09-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2005.09.004
更新日期:2006-01-30 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(81)90118-0
更新日期:1981-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:1992-02-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(83)90121-1
更新日期:1983-11-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(84)90189-8
更新日期:1984-02-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(78)90058-8
更新日期:1978-01-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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更新日期:1999-01-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2011-04-25 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2012.01.004
更新日期:2012-03-10 00:00:00
abstract::Previously we have shown that systemic injection of adenosine antagonists can significantly improve cold tolerance in both rats and humans. However, it is not clear whether systemic administration of adenosine antagonist acts peripherally or centrally at the thermoregulatory site. To resolve this, theophylline (nonsel...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(90)90094-g
更新日期:1990-03-01 00:00:00
abstract::The place conditioning paradigm has proven successful in identifying the neural mechanisms of drug reinforcement. Two classes of drugs, opiates and psychomotor stimulants, have received the most study, and in each case an important role for DA neurons of the mesolimbic system has been established. Moreover, both recep...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(89)90224-4
更新日期:1989-10-01 00:00:00
abstract::Methylphenidate (MPD) is currently one of the most prescribed drug therapies for attention deficit/hyperactivity disorder (ADHD) and moreover is abused for cognitive enhancement and used for recreation by the young and adults. Methylphenidate is used for prolonged periods of time and its mechanism of action on the bra...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2011.10.008
更新日期:2012-03-10 00:00:00
abstract::In precollicular decerebrate cats, the vestibulospinal reflex (VSR) was intermittently recorded from the triceps brachii during sinusoidal roll tilt of the whole animal (at 0.15 Hz, +/- 10 degrees), leading to selective stimulation of labyrinth receptors. This reflex, tested during and after a 3-h period of sustained ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(94)90156-2
更新日期:1994-01-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(80)90195-1
更新日期:1980-03-01 00:00:00
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journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2005.09.020
更新日期:2006-03-15 00:00:00
abstract::Interleukin-33 (IL-33) is closely related to the regulation of immunological cells, and its receptor ST2 is a member of the interleukin-1 (IL-1) receptor family. Inflammatory responses play critical roles in neuronal damage and white matter injury (WMI) post intracerebral hemorrhage (ICH). In this study, we tried to e...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2019.05.016
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:In humans, activation of the diving reflex by a cold stimulus to the face results in bradycardia, peripheral vasoconstriction and an increase in blood pressure. However, responses of the cerebral blood flow have not yet been evaluated. We undertook this study to assess the effect of cold face sti...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(03)00065-0
更新日期:2003-06-30 00:00:00