Sleep deprivation abolishes the locomotor stimulant effect of ethanol in mice.

abstract：:The effects of unilateral and bilateral electrolytic lesions of the dorsal raphe nuclei (DRN) of 30-day-old rats, on the spontaneous and induced ovulation, were analyzed. The bilateral lesion and the lesion on the right side of the DRN delayed the age of first vaginal estrous. None of the animals with bilateral lesion...

journal_title：Brain research bulletin

authors： Ayala ME,Rosas P,Dominguez R

更新日期：1994-01-01 00:00:00

abstract：:Brain serotonin (5-HT) levels and accumulation rate within the dorsal raphe nucleus (DR) were elevated in ovariectomized (OVX) rats after ovarian steroid treatment, which consisted of estradiol benzoate (EB) followed by progesterone (P) 48 hr later. Some animals were also given the monoamine oxidase (MAO) inhibitor pa...

journal_title：Brain research bulletin

authors： Cone RI,Davis GA,Goy RW

更新日期：1981-12-01 00:00:00

abstract：:We studied the effects of estradiol (E2) and progesterone (P) on progesterone receptor (PR) isoforms gene expression in the brain of ovariectomised female and gonadectomised male rats by RT-PCR analysis. In female rats, the expression of both PR isoforms was induced by E2 and down-regulated by P in the hypothalamus, w...

journal_title：Brain research bulletin

authors： Guerra-Araiza C,Coyoy-Salgado A,Camacho-Arroyo I

更新日期：2002-10-30 00:00:00

abstract：:The present work describes a series of experiments designed to examine the possible role of central 5-HT circuits in the control of feeding and drinking in pigeons. Acute effects (within 1 h) of intracerebroventricular (ICV) injections of 5-HT (0, 9.7, 19.4, 38.7, 77.5, 155, and 310 nmol) in 24-h food-deprived (24FD) ...

journal_title：Brain research bulletin

authors： Steffens SM,Casas DC,Milanez BC,Freitas CG,Paschoalini MA,Marino-Neto J

更新日期：1997-01-01 00:00:00

abstract：:Retinal injuries and diseases are major causes of human disability involving vision impairment by the progressive and permanent loss of retinal neurons. During development, assembly of this tissue entails a successive and overlapping, signal-regulated engagement of complex events that include proliferation of progenit...

journal_title：Brain research bulletin

authors： Ventura ALM,Dos Santos-Rodrigues A,Mitchell CH,Faillace MP

更新日期：2019-09-01 00:00:00

abstract：:We have examined the effects of the presence of the mutated human presenilin 1 gene (M146L; hps1*) on lesion-induced sprouting in the hippocampus of the mouse (C57/CBA). The entorhinal cortex was unilaterally lesioned with ibotenic acid in adult, male mice. Four weeks later the subsequent axonal sprouting in the denta...

journal_title：Brain research bulletin

authors： Kadish I,Pradier L,van Groen T

更新日期：2002-03-15 00:00:00

abstract：:Chronic exposure to drugs and alcohol leads to damage to dopaminergic neurons and their projections in the 'reward pathway' that originate in the ventral tegmental area (VTA) and terminate in the nucleus accumbens (NAc). This damage is thought to contribute to the signature symptom of addiction: chronic relapse. In th...

journal_title：Brain research bulletin

authors： Venkiteswaran K,Alexander DN,Puhl MD,Rao A,Piquet AL,Nyland JE,Subramanian MP,Iyer P,Boisvert MM,Handly E,Subramanian T,Grigson PS

更新日期：2016-05-01 00:00:00

abstract：:The study examines the influence of vestibular and leg proprioceptive cues on the maintenance of the body vertical in human stance. Vestibular body orientation cues were changed by applying bipolar currents to both mastoid bones (cosine-bell wave form of 3.3 s duration, 1 mA current intensity). Proprioceptive input wa...

journal_title：Brain research bulletin

authors： Hlavacka F,Mergner T,Krizkova M

更新日期：1996-01-01 00:00:00

abstract：:Endogenous adrenergic drive regulates the firing rate of serotonergic neurons. However, advocates of feedback theory assert that 5-hydroxytryptamine (5-HT) released in the somatodendritic region of raphe neurons regulates both rate and release of 5-HT. Experiments were done to determine if the somatodendritic region m...

journal_title：Brain research bulletin

authors： Kalsner S,Abdali SA

更新日期：2001-08-01 00:00:00

abstract：:An understanding of the distribution of manganese ions in the brain is of interest in connection with the development of an understanding of the neurotoxicity of this element. Information about the time dependent biodistribution of manganese ions in the brains of intact rats subsequent to single IP injections of MnCl2...

journal_title：Brain research bulletin

authors： London RE,Toney G,Gabel SA,Funk A

更新日期：1989-09-01 00:00:00

abstract：:Neonatal post-hemorrhagic hydrocephalus is associated with cognitive decline and a serious deterioration in the patient's quality of life. The underlying impairments to neurons are not well understood. Here, we used the method described by Cherian et al. to construct a model of hydrocephalus after intra-ventricular he...

journal_title：Brain research bulletin

authors： Chen X,Huang X,Li B,Zhao Z,Jiang L,Huang C,Lu Y

更新日期：2010-08-30 00:00:00

abstract：:Maternal immune activation during pregnancy is a risk factor for neurodevelopmental disorders, such as schizophrenia; however, a full mechanistic understanding has yet to be established. The activity of a transient cell population, the subplate neurons, is critical for the development of cortical inhibition and functi...

journal_title：Brain research bulletin

authors： Beamer E,Kovács G,Sperlágh B

更新日期：2017-10-01 00:00:00

abstract：:On the basis of the evidence that approximately 45% of Schaffer collateral boutons are zinc-positive, zinc release from Schaffer collaterals and its action were examined in hippocampal slices. When zinc release from Schaffer collaterals was examined using ZnAF-2, a membrane-impermeable zinc indicator, ZnAF-2 signal in...

journal_title：Brain research bulletin

authors： Takeda A,Nakajima S,Fuke S,Sakurada N,Minami A,Oku N

更新日期：2006-02-15 00:00:00

abstract：:Accumulating evidence points to the amyloid-β (Aβ) peptide as the culprit in the pathogenesis of Alzheimer's disease (AD). β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a protease that is responsible for initiating Aβ production. Although precise mechanisms that trigger Aβ accumulation remain unc...

journal_title：Brain research bulletin

authors： Ohno M

更新日期：2016-09-01 00:00:00

abstract：:This study analyzed the projection neurons of the anterior subdivision of the rat basolateral amygdaloid nucleus (BLa) by correlating the morphology of Golgi-stained neurons with the morphology of neurons that were retrogradely labeled by injections into the main terminal fields of BLa. In each animal multiple injecti...

journal_title：Brain research bulletin

authors： McDonald AJ

更新日期：1992-02-01 00:00:00

abstract：:Mechanisms underlying shock-induced conditioned fear - a paradigm frequently used to model posttraumatic stress disorder, PTSD - are usually studied shortly after shocks. Some of the brain regions relevant to conditioned fear were activated in all the c-Fos studies published so far, but the overlap between the activat...

journal_title：Brain research bulletin

authors： Tulogdi A,Sörös P,Tóth M,Nagy R,Biró L,Aliczki M,Klausz B,Mikics E,Haller J

更新日期：2012-07-01 00:00:00

abstract：:The effect of subarachnoid hemorrhage (SAH) on the neuropeptides and mast cells of the rat dura mater has not been reported. We examined the outcome of SAH on the rat supratentorial dura mater to determine whether dural nerves undergo effects similar to those of nerves accompanying cerebral blood vessels after SAH. Fo...

journal_title：Brain research bulletin

authors： Keller JT,Mullen BG,Zuccarello M

更新日期：1993-01-01 00:00:00

abstract：:Although neural occlusion has been suggested to occur between the central and reflex mechanisms increasing arterial pressure, evidence consistent with this phenomenon is lacking. To assess the possibility of neural occlusion we recorded, in chloralose-anesthetized cats, the pressor responses to statically contracting ...

journal_title：Brain research bulletin

authors： Rybicki KJ,Stremel RW,Iwamoto GA,Mitchell JH,Kaufman MP

更新日期：1989-02-01 00:00:00

abstract：:Interferon-alpha (IFN-alpha, 2.0 x 10(4) units) was bilaterally microinjected into the medial preoptic area and anterior hypothalamus in conscious rats treated 10 min prior with an opioid receptor antagonist, naloxone (NLX, 2 mg/kg, IM) or a prostaglandin synthetase inhibitor, acetaminophen (ACAP, 25 mg/kg, IM). The I...

journal_title：Brain research bulletin

authors： Nakashima T,Murakami T,Murai Y,Hori T,Miyata S,Kiyohara T

更新日期：1995-01-01 00:00:00

abstract：:Methoxetamine (MXE) is a novel psychoactive compound (NPS) that emerged in 2010 as a substitute for the dissociative anaesthetic ketamine. MXE has a reputation of carrying a lower risk of harm than ketamine, however a number of deaths have been reported. Currently very little is known about the psychopharmacological e...

journal_title：Brain research bulletin

authors： Horsley RR,Lhotkova E,Hajkova K,Jurasek B,Kuchar M,Palenicek T

更新日期：2016-09-01 00:00:00

abstract：:The chronic mild stress (CMS) model has been used as an animal model of depression which induces anhedonic behavior in rodents. The present study was aimed to evaluate the behavioral and physiological effects of administration of beta-carboline harmine in rats exposed to CMS procedure. To this aim, after 40 days of ex...

journal_title：Brain research bulletin

authors： Fortunato JJ,Réus GZ,Kirsch TR,Stringari RB,Fries GR,Kapczinski F,Hallak JE,Zuardi AW,Crippa JA,Quevedo J

更新日期：2010-03-16 00:00:00

abstract：:After spinal cord injury (SCI) of the cat or rat neuronal centres below the level of lesion exhibit plasticity that can be exploited by specific training paradigms. In individuals with complete or incomplete SCI, human spinal locomotor centers can be activated by appropriate afferent input. This includes to facilitate...

journal_title：Brain research bulletin

authors： Dietz V

更新日期：2009-01-15 00:00:00

abstract：:Recently published work in the rat has shown that: the incidence of electrical coupling, as measured by dye coupling, is decreased from control levels by 8 days of drinking hypertonic saline; an index of circulating testosterone, seminal vesicle weight, is also decreased by 8 days of saline drinking; and both plasma a...

journal_title：Brain research bulletin

authors： Cobbett P,Yang QZ,Hatton GI

更新日期：1987-03-01 00:00:00

abstract：:A reduction in nerve conduction velocity and an increase in resistance to ischemic conduction failure are early signs of neural dysfunction in both diabetic patients and animal models of diabetes. The effect of Bimoclomol (BRLP-42), a drug under clinical development for the treatment of diabetic complications, on expe...

journal_title：Brain research bulletin

authors： Bíró K,Jednákovits A,Kukorelli T,Hegedüs E,Korányi L

更新日期：1997-01-01 00:00:00

abstract：:A preembedding double immunostaining technique using antibodies against methionine-enkephalin and tyrosine hydroxylase was used to study synaptic relations between enkephalinergic and catecholaminergic neurons in the area postrema of the rat at the electron microscopic level. The large nuclei-containing cell bodies of...

journal_title：Brain research bulletin

authors： Guan JL,Wang QP,Shioda S,Ochiai H,Nakai Y

更新日期：1995-01-01 00:00:00

abstract：:This paper reviews and provides new data on the relationship of the peptide content in rat dorsal root ganglion (DRG) neurons to a) the neurofilament content of the soma and b) the conduction velocities of the fibres. The latter involved intracellular recordings made in vitro followed by dye injection and immunocytoch...

journal_title：Brain research bulletin

authors： Lawson SN,Perry MJ,Prabhakar E,McCarthy PW

更新日期：1993-01-01 00:00:00

abstract：:Axons of retinal ganglion cells showed responses not previously emphasized: (a) many tonic units discharged oscillations, 2--12 spikes per burst, interburst intervals 20--300 msec; (b) phasic units showed concentric or flanking ON and OFF fields, response frequency depended on balance of retinal excitation and inhibit...

journal_title：Brain research bulletin

authors： O'Benar JD

更新日期：1976-11-01 00:00:00

abstract：:The place conditioning paradigm has proven successful in identifying the neural mechanisms of drug reinforcement. Two classes of drugs, opiates and psychomotor stimulants, have received the most study, and in each case an important role for DA neurons of the mesolimbic system has been established. Moreover, both recep...

journal_title：Brain research bulletin

authors： Hoffman DC

更新日期：1989-10-01 00:00:00

abstract：:This review focuses on the maturation of brain white-matter, as revealed by magnetic resonance (MR) imaging carried out in healthy subjects. The review begins with a brief description of the nature of the MR signal and its possible biological underpinnings, and proceeds with a description of MR findings obtained in ne...

journal_title：Brain research bulletin

authors： Paus T,Collins DL,Evans AC,Leonard G,Pike B,Zijdenbos A

更新日期：2001-02-01 00:00:00

abstract：:The catecholamines dopamine, epinephrine and norepinephrine, as well as the indoleamine serotonin were measured using radioenzymatic assays, in the frontal cortex of normal rats and of rats in which serotonin synthesis had been inhibited with p-chlorophenylalanine. Besides serotonin, norepinephrine levels were signifi...

journal_title：Brain research bulletin

authors： Reader TA

更新日期：1982-05-01 00:00:00