Theta in hippocampal slices: relation to synaptic responses of dentate neurons.

abstract：:The possible competition of MIF-1 (Pro-Leu-Gly-NH2) with 3H-naloxone or 3H-D-Ala-D-Leu-enkephalin (DADLE) for mu and delta opiate receptors in the rat striatum was examined under conditions of varying temperatures and concentrations of sodium and GTP. MIF-1, in concentrations ranging from 10(-14) to 10(-3) M, failed t...

journal_title：Brain research bulletin

authors： Luciano MG,Zadina JE,Kastin AJ,Coy DH

更新日期：1981-12-01 00:00:00

abstract：:Phase and amplitude depth profiles of EEG theta-like activity (TLA) induced by bath perfusion of 50 micro M of the cholinergic agonist carbachol were investigated using rat hippocampal formation slices. The data showed that the amplitude and phase of laminar profiles of TLA recorded in vitro were the same as the type ...

journal_title：Brain research bulletin

authors： Kowalczyk T,Konopacki J

更新日期：2002-09-30 00:00:00

abstract：:Little is known about the behavioral, nutritional, and metabolic events that control dietary intake quality. Two experiments are described that manipulate nutritional conditions that have been hypothesized to affect dietary item choice so as to assess what effect, if any, the added factor of genetic obesity has in mod...

journal_title：Brain research bulletin

authors： Castonguay TW,Rowland NE,Stern JS

更新日期：1985-06-01 00:00:00

abstract：:The role of calmodulin (CaM) in organelle motility (fast axonal transport) in the axoplasm of the squid giant axon was evaluated directly using video-enhanced microscopy. Addition of 6 microM CaM to extruded squid axoplasm produced a 2.6-fold increase in the number of organelles moving per minute per unit area of axop...

journal_title：Brain research bulletin

authors： Rivera DT,Langford GM,Weiss DG,Nelson DJ

更新日期：1995-01-01 00:00:00

abstract：:The putative behavioral effects of the enantiomers of BAY K 8644 and the behavioral responses to (+/-)-BAY K 8644 following chronic injection were assessed on motor function in mice. The interaction of the enantiomers of BAY K 8644 with mouse brain dihydropyridine binding sites was also evaluated. The calcium channel ...

journal_title：Brain research bulletin

authors： O'Neill SK,Bolger GT

更新日期：1988-12-01 00:00:00

abstract：:Neonatal rats, when spinalized on the fourteenth postnatal day, showed minimal recovery of function in their hindlimbs. Bridging the cut spinal cord with E16 fetal spinal cord tissue did not improve functional recovery. Bridging, plus treatment with GM1 ganglioside, caused a significant (p less than 0.05) improvement ...

journal_title：Brain research bulletin

authors： Commissiong JW,Sauve Y,Csonka K,Karoum F,Toffano G

更新日期：1991-07-01 00:00:00

abstract：:Bilateral inferior olive lesions, produced by systemic administration of the neurotoxin 3-acetylpyridine (3AP) produce a proconvulsant state specific for strychnine-induced seizures and myoclonus. We have proposed that these phenomena are mediated through increased excitation of cerebellar Purkinje cells, through acti...

journal_title：Brain research bulletin

authors： Anderson MC,Chung EY,Van Woert MH

更新日期：1990-10-01 00:00:00

abstract：:Five polymorphisms (rs4713916, rs4713902, rs1360780, rs9296158 and rs3800373) of FKBP5 gene were analyzed in a case-control study comprising 423 Mexican individuals (146 individuals with suicide attempt and 277 controls). The SNP's were genotyped using the TaqMan-allelic assay. Genotype and allele frequencies were com...

journal_title：Brain research bulletin

authors： Hernández-Díaz Y,González-Castro TB,Tovilla-Zárate CA,Juárez-Rojop IE,López-Narváez ML,Pérez-Hernández N,Rodríguez-Pérez JM,Genis-Mendoza AD

更新日期：2021-01-01 00:00:00

abstract：:Neuropathic pain (NP) is a challenge due to our limited understanding of the mechanisms that initiate and maintain chronic pain. The prelimbic division (PrL) of the medial prefrontal cortex (mPFC) is an important area of the emotional and cognitive components of pain and pharmacological systems can interact into the n...

journal_title：Brain research bulletin

authors： Medeiros P,Oliveira-Silva M,Negrini-Ferrari SE,Medeiros AC,Elias-Filho DH,Coimbra NC,de Freitas RL

更新日期：2020-12-01 00:00:00

abstract：:Polymerase chain reaction assays are a powerful tool for detecting the presence of infectious genomes in the cerebrospinal fluid. Positive results always mean a current or pending infection of the central nervous system. Subacute (>7 days) or chronic infections induce an intrathecal humoral immune response and the app...

journal_title：Brain research bulletin

authors： Sindic CJ,Van Antwerpen MP,Goffette S

更新日期：2003-08-15 00:00:00

abstract：:The ability of homotypic cortical tissue grafts to induce recovery of function after a gustatory neocortex (GN) lesion was studied using the conditioned taste aversion (CTA) paradigm. On acquisition day, 26 GN-lesioned and 8 sham-lesioned rats were presented with a saccharin solution, followed by an injection of the i...

journal_title：Brain research bulletin

authors： Yirmiya R,Zhou FC,Holder MD,Deems DA,Garcia J

更新日期：1988-05-01 00:00:00

abstract：:Pax6 is an important transcription factor expressed in several discrete domains of the developing central nervous system. It has been reported that Pax6 is involved in the specification of subtypes of hindbrain motor neurons. Pax6 homozygous mutant (rSey2/rSey2) rats die soon after birth, probably due to impaired resp...

journal_title：Brain research bulletin

authors： Ikeda K,Onimaru H,Inada H,Tien Lin S,Arata S,Osumi N

更新日期：2019-10-01 00:00:00

abstract：:The present study examined whether the induction of scent marking behavior and grooming of the flank gland region by injection of arginine-vasopressin (AVP) or oxytocin (OXY) into the anterior hypothalamus-medial preoptic area (AH-MPOA) required the presence of the flank glands. The flank glands were surgically remove...

journal_title：Brain research bulletin

authors： Albers HE,Ferris CF

更新日期：1986-09-01 00:00:00

abstract：:Urethane is often used as a central anaesthetic in neurophysiological studies of drug effects. In this experiment, the effect of morphine on cortical EEG and single units of hippocampus and medial thalamus were compared in urethane-anaesthetized and paralyzed-awake rats. In each case, there was evidence of a morphine-...

journal_title：Brain research bulletin

authors： Linseman MA

更新日期：1980-03-01 00:00:00

abstract：:Neonatal hippocampal lesions in rats produce behavioral and neurochemical abnormalities post-puberty that are used in animal models for developmentally linked pathology in schizophrenia. In one model, adult rats exhibit enhanced sensitivity to the locomotor-activating effects of amphetamine, if they had sustained exci...

journal_title：Brain research bulletin

authors： Swerdlow NR,Halim N,Hanlon FM,Platten A,Auerbach PP

更新日期：2001-05-01 00:00:00

abstract：:We showed previously that the number and time of spike-wave discharges (SWDs) were increased after intraperitoneal (i.p.) injection of lipopolysaccharide (LPS), an effect, which was completely abolished by cyclooxygenase-2 (COX-2) inhibitor indomethacin (IND) pretreatment in Wistar Albino Glaxo/Rijswijk (WAG/Rij) rats...

journal_title：Brain research bulletin

authors： Kovács Z,Dobolyi A,Juhász G,Kékesi KA

更新日期：2014-05-01 00:00:00

abstract：:The effects of intracarotidly injected neuropeptide Y (NPY; 0.1 micrograms/kg) on the local cerebral blood volume (CBV) and blood flow (CBF) in the parieto-temporal cortex were examined by the photoelectric method in 17 anesthetized cats. CBV reflects the cumulative crosssectional area of the cerebral microvascular be...

journal_title：Brain research bulletin

authors： Kobari M,Fukuuchi Y,Tomita M,Tanahashi N,Yamawaki T,Takeda H,Matsuoka S

更新日期：1993-01-01 00:00:00

abstract：:We propose that separate sensory and hedonic representations exist in each of the primary structures of the somatosensory system, including brainstem, thalamic and cortical components. In the dorsal horn of the spinal cord, the hedonic representation, which consists primarily of nociceptive-specific, wide dynamic rang...

journal_title：Brain research bulletin

authors： Sewards TV,Sewards M

更新日期：2002-07-01 00:00:00

abstract：:In this study, we compared the depression-like symptoms induced by olfactory bulbectomy (OBX) in the two inbred Wistar and Long Evans rat strains. We also analyzed the self-regulated oral intake of nicotine in these strains and the effect of nicotine on the depression-like symptoms of olfactory bulbectomy. Furthermore...

journal_title：Brain research bulletin

authors： Vieyra-Reyes P,Mineur YS,Picciotto MR,Túnez I,Vidaltamayo R,Drucker-Colín R

更新日期：2008-09-05 00:00:00

abstract：:Gamma-secretase (GS) is an enzyme complex that cleaves numerous substrates, and it is best known for cleaving amyloid precursor protein (APP) to form amyloid-beta (Aβ) peptides. Aberrant cleavage of APP can lead to Alzheimer's disease, so much research has been done to better understand GS structure and function in ho...

journal_title：Brain research bulletin

authors： Carroll CM,Li YM

更新日期：2016-09-01 00:00:00

abstract：:The glutamatergic system is an important target in many neurodegenerative diseases and for several neurotoxic drugs. Organotellurium compounds are often very good free radical scavengers' agents. Recently, we reported that diethyl-2-phenyl-2-tellurophenyl vinylphosphonate is a compound with low toxicity in vitro and i...

journal_title：Brain research bulletin

authors： Avila DS,Gubert P,Palma A,Colle D,Alves D,Nogueira CW,Rocha JB,Soares FA

更新日期：2008-05-15 00:00:00

abstract：:Accumulating evidence points to the amyloid-β (Aβ) peptide as the culprit in the pathogenesis of Alzheimer's disease (AD). β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a protease that is responsible for initiating Aβ production. Although precise mechanisms that trigger Aβ accumulation remain unc...

journal_title：Brain research bulletin

authors： Ohno M

更新日期：2016-09-01 00:00:00

abstract：:Methylphenidate (MPD), commonly known as Ritalin, is the most frequently prescribed drug to treat children and adults with attention deficit hyperactivity disorder (ADHD). Adolescence is a period of development involving numerous neuroplasticities throughout the central nervous system (CNS). Exposure to a psychostimul...

journal_title：Brain research bulletin

authors： Yang PB,Swann AC,Dafny N

更新日期：2006-12-11 00:00:00

abstract：:Increasing evidence supports that dopamine (DA) plays an important role in the hippocampal function via activation of D1-like receptors (D1Rs). As the entry structure of the hippocampal formation, the hippocampal dentate gyrus (DG) is critically involved in spatial learning and memory. Despite a number of studies inve...

journal_title：Brain research bulletin

authors： Wang F,Wan P,Wang W,Xiao B,Jin H,Jin Q

更新日期：2019-01-01 00:00:00

abstract：:Developmental changes in the control of neurite extension by extracellular factors can be examined by utilizing cultures of neurons from various aged embryos. Several conditioned media and tissue extracts were added to cultures of chick embryo retinal neurons on collagen substrates for 1, 3 and 5 days in vitro. Neurit...

journal_title：Brain research bulletin

authors： Thompson JM,Lu AH,Ruch S

更新日期：1987-04-01 00:00:00

abstract：:We recently reported that human recombinant interleukin-6 (hrIL-6) microinjected into the preoptic area (POA) of guinea pigs induced fever at high doses, suggesting that IL-6 may be another endogenous pyrogen. This study was undertaken to determine whether hrIL-6 affects the single-unit activity of thermosensitive and...

journal_title：Brain research bulletin

authors： Xin L,Blatteis CM

更新日期：1992-07-01 00:00:00

abstract：:"Responder" Sprague-Dawley (SD) rats that were sensitive to electroacupuncture (EA) in an acute thermal pain test (i.e. tail flick latency [TFL] test) maintained sensitivity to EA in the warm allodynia test after peripheral nerve injury. Similarly, the "non-responder" SD rats that were insensitive to EA in the TFL tes...

journal_title：Brain research bulletin

authors： Kim SK,Moon HJ,Park JH,Lee G,Shin MK,Hong MC,Bae H,Jin YH,Min BI

更新日期：2007-10-19 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the mature brain. At an early developmental period, it acts in an excitatory manner that influences many processes of proliferation, migration, and differentiation of the neurons. Previous evidence indicated that manipulation of the GABAergi...

journal_title：Brain research bulletin

authors： Naderipoor P,Amani M,Abedi A,Sakhaie N,Sadegzadeh F,Saadati H

更新日期：2021-01-10 00:00:00

abstract：:Nicotinic acetylcholine (ACh) and dopamine (DA) receptor activation has been found to be important for working memory. The regional distribution of these receptors in the brain has been well characterized. However, the relationship of the region-specific nicotinic ACh and DA binding density to memory performance has n...

journal_title：Brain research bulletin

authors： Levin ED,Torry D,Christopher NC,Yu X,Einstein G,Schwartz-Bloom RD

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To establish a link between tryptophan (a precursor for 5-hydroxytryptamine (5-HT) or serotonin, involved in sleep and fatigue) and post-operative fatigue after major surgery. BACKGROUND:There is a link between tryptophan (the precursor for the neurotransmitter 5-hydroxytryptamine), and its competitive bindi...

journal_title：Brain research bulletin

authors： McGuire J,Ross GL,Price H,Mortensen N,Evans J,Castell LM

更新日期：2003-04-15 00:00:00