当前位置： SCI文献检索 > BRAIN RESEARCH BULLETIN期刊下所有文献 > Partial recovery of gustatory function after neural tissue transplantation to the lesioned gustatory neocortex.

Partial recovery of gustatory function after neural tissue transplantation to the lesioned gustatory neocortex.

Abstract：

:The ability of homotypic cortical tissue grafts to induce recovery of function after a gustatory neocortex (GN) lesion was studied using the conditioned taste aversion (CTA) paradigm. On acquisition day, 26 GN-lesioned and 8 sham-lesioned rats were presented with a saccharin solution, followed by an injection of the illness-inducing agent lithium chloride (LiCl). On the test day, 2 days later, saccharin was presented again. The GN-lesioned rats showed significantly less aversion to saccharin on the test day, indicating that the lesion impaired their ability to form taste-illness association. Nine of the lesioned rats were then bilaterally transplanted with fetal GN tissue. Nine weeks after the transplantation, the rats were presented with a LiCl solution, which served as both a tastant and an illness-inducing agent. An NaCl solution, which tasted very similar to the LiCl solution, was used to test the CTA to salt 3 days later. The nontransplanted rats consumed significantly more LiCl than the transplanted and sham-operated rats on the acquisition day, but both transplanted and nontransplanted rats consumed more NaCl than sham-operated rats on the test day. Nissl and Golgi stainings showed numerous somata and extensive arborization of neurons within the grafts. The results indicate that fetal GN grafts can restore the ability to integrate gustatory and visceral inputs but not to form long-lasting taste-illness associations.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Yirmiya R,Zhou FC,Holder MD,Deems DA,Garcia J

doi

10.1016/0361-9230(88)90222-5

subject

Has Abstract

pub_date

1988-05-01 00:00:00

pages

619-25

issue

5

eissn

0361-9230

issn

1873-2747

pii

0361-9230(88)90222-5

journal_volume

20

pub_type

杂志文章

相关文献

BRAIN RESEARCH BULLETIN文献大全
  • Effects of intraplantar injection of carrageenan on central dopamine release.

    abstract：:The present study examined the changes of extracellular concentration of dopamine and its metabolite homovanillic acid in the striatum, the periaqueductal gray and the dorsal horn of lumbar spinal cord following intraplantar injection of carrageenan. In vivo microdialysis and high-performance liquid chromatography wit...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(00)00460-3

    authors： Gao X,Zhang YQ,Zhang LM,Wu GC

    更新日期：2001-03-01 00:00:00

  • beta-Amyloid-induced toxicity in rat hippocampal cells: in vitro evidence for the involvement of free radicals.

    abstract：:The conditions under which amyloid is toxic to primary rat hippocampal neurons were investigated. Synthetic A beta (1-42) peptide elicited neurotoxic activity following "aging" for 7 to 14 days at 37 degrees C in Modified Eagles Media. Neurotoxicity included decreases in neurite length, cell number, and a loss in 3-[4...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(95)02034-x

    authors： Manelli AM,Puttfarcken PS

    更新日期：1995-01-01 00:00:00

  • Localization of tissue plasminogen activator mRNA in adult rat brain.

    abstract：:The distribution of tissue plasminogen activator (tPA) messenger RNA in rat brain was studied using in situ hybridization with 35S UTP-labeled RNA probes derived from a full-length tPA cDNA. Sense strand controls produced low, even backgrounds, with small elevations in the hippocampus. Full-length antisense probes pro...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(95)00008-3

    authors： Ware JH,Dibenedetto AJ,Pittman RN

    更新日期：1995-01-01 00:00:00

  • Neuroanatomical investigation of the gonadotrophin-releasing hormone 1 system in the seasonally breeding Cape dune mole-rat, Bathyergus suillus.

    abstract：:The gonadotrophin-releasing hormone 1 (GnRH1) system has been investigated immunohistochemically in Cape dune mole-rats (Bathyergus suillus), subterranean rodents that normally display severe aggression towards conspecifics. These animals breed seasonally and show a reduced mean plasma level of luteinising hormone dur...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2008.07.004

    authors： Hart L,Bennett NC,Kalamatianos T,Oosthuizen MK,Jarvis JU,O'Riain MJ,Coen CW

    更新日期：2008-10-22 00:00:00

  • Input from the medial septum regulates adult hippocampal neurogenesis.

    abstract：:Neural progenitors in the subgranular zone of the hippocampal formation form a continuously proliferating cell population, generating new granule neurons throughout adult life. Between 10 days and 1 month after their formation, many of the newly generated cells die. The present study investigated whether a partial les...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2005.06.018

    authors： Van der Borght K,Mulder J,Keijser JN,Eggen BJ,Luiten PG,Van der Zee EA

    更新日期：2005-09-30 00:00:00

  • Expression and functional characterization of transient receptor potential vanilloid 4 in the dorsal root ganglion and spinal cord of diabetic rats with mechanical allodynia.

    abstract：:Diabetic mechanical allodynia (DMA) is a common manifestation in patients with diabetes mellitus, and currently, no effective treatment is available. Transient receptor potential vanilloid 4 (TRPV4) is involved in mechanical hypersensitivity resulting from varying aetiologies in animal, but its expression pattern duri...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2020.05.010

    authors： Cui YY,Li MY,Li YT,Ning JY,Gou XC,Shi J,Li YQ

    更新日期：2020-09-01 00:00:00

  • Frontostriatal deficits in unipolar major depression.

    abstract：:Recent accounts of major depression have tended to focus on dysfunction of frontothalamic-striatal reentrant circuits as a possible source of the disorder. Evidence of frontostriatal involvement in unipolar major depression from lesion and neuropsychological studies, and functional and structural imaging studies is ex...

    journal_title：Brain research bulletin

    pub_type： 杂志文章,评审

    doi：10.1016/s0361-9230(98)00126-9

    authors： Rogers MA,Bradshaw JL,Pantelis C,Phillips JG

    更新日期：1998-11-01 00:00:00

  • Activation of orexin/hypocretin projections to basal forebrain and paraventricular thalamus by acute nicotine.

    abstract：:Orexin/hypocretin neurons of the lateral hypothalamus/perifornical area project to a diverse array of brain regions and are responsive to a variety of psychostimulant drugs. It has been shown that orexin neurons are activated by systemic nicotine administration suggesting a possible orexinergic contribution to the eff...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2008.09.014

    authors： Pasumarthi RK,Fadel J

    更新日期：2008-12-16 00:00:00

  • An electrophysiological and behavioural study of self-stimulation in the orbitofrontal cortex of the rhesus monkey.

    abstract：:It was found that neurons in the posterior orbitofrontal cortex, area 13, of the rhesus monkey were activated from self-stimulation electrodes (in 142 of 168 possible instances), and that neurons in the anterior orbitofrontal areas were much less likely to be activated from the self-stimulation electrodes (in only 28 ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(80)90181-1

    authors： Mora F,Avrith DB,Rolls ET

    更新日期：1980-03-01 00:00:00

  • Electrophysiological study of neurotropin-induced responses in guinea pig hypothalamic neurons.

    abstract：:To investigate the direct actions of neurotropin (NSP, a nonproteinaceous extract from inflamed skin of rabbits which is in therapeutic use), intracellular recordings were made from neurons of the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LHA) in slices of guinea pig brain. In the VMH, NSP...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(92)90144-m

    authors： Shimizu N,Duan S,Hori T,Oomura Y

    更新日期：1992-12-01 00:00:00

  • Similar effects of estrogen and lateral hypothalamic lesions on feeding behavior of female rats.

    abstract：:Many similarities exist between the inhibitory influence of estrogen on food intake (FI) and body weight (BWt) in female rats and the effect of lateral hypothalamic (LH) lesions on energy balance. Thus, a possible interaction of small electrolytic LH lesions (0.8 mA/10 sec) with hormone-dependent changes in FI, BWt an...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(78)90085-0

    authors： Nance DM,Gorski RA

    更新日期：1978-09-01 00:00:00

  • Organization of GABA and GABA-transaminase containing neurons in the gustatory zone of the nucleus of the solitary tract.

    abstract：:Previous cytoarchitectural and electron micrographic studies have indicated that the gustatory zone of the nucleus of the solitary tract (NST) may contain local circuit neurons. It is known that neurons of the caudal "visceroceptive" NST contain GABA, glutamic acid decarboxylase (EC 4.1.1.15), and GABA-transaminase (G...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(88)90202-x

    authors： Lasiter PS,Kachele DL

    更新日期：1988-10-01 00:00:00

  • Golgi impregnated somatostatin immunoreactive neurons in lamina II of the rat spinal cord.

    abstract：:The morphology of somatostatin immunoreactive (SOM-I) neurons in lamina (L) II of the rat spinal cord was determined using a combination of Golgi impregnation and immunohistochemistry. Golgi-impregnated SOM-I neurons that resembled islet, stalked and other cells were observed. Islet cells are considered to be inhibito...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(92)90192-z

    authors： Mather CS,Ho RH

    更新日期：1992-02-01 00:00:00

  • Fate of septohippocampal neurons following intracerebroventricular injections of colchicine.

    abstract：:Injection of colchicine into the lateral ventricles (ICV) of rats results in a selective loss of neurons immunoreactive for choline acetyltransferase (ChAT) in the medial septum (MS) and a concomitant loss of acetylcholinesterase (AChE) positive fibers in the hippocampus. To determine if this loss of cholinergic cells...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(92)90132-h

    authors： Ginn SR,Peterson GM

    更新日期：1992-11-01 00:00:00

  • Changes in retention of a visual discrimination task following unilateral and bilateral transections of temporo-entorhinal connections in rats.

    abstract：:In a previous study, it was shown that the lateral entorhinal cortex (LEC) in the left hemisphere contains higher concentration of glutamate than in the right hemisphere. The purpose of the present study was to examine potential relationship between this neurochemical asymmetry and behavior. Rats with either left, rig...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(90)90074-a

    authors： Myhrer T,Iversen EG

    更新日期：1990-08-01 00:00:00

  • Association of dopaminergic terminals and neurons releasing nitric oxide in the rat striatum: an electron microscopic study using NADPH-diaphorase histochemistry and tyrosine hydroxylase immunohistochemistry.

    abstract：:To examine synaptic input and association of terminals containing dopamine and other transmitters to rat striatal nitric oxide synthase-expressing neurons, an electron microscopic study using tyrosine hydroxylase (TH) immunohistochemistry combined with histochemistry for NADPH-diaphorase (NADPHd) was performed. NADPHd...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(96)00035-4

    authors： Fujiyama F,Masuko S

    更新日期：1996-01-01 00:00:00

  • REM-dreams recall in patients with narcolepsy-cataplexy.

    abstract：:An abundant recall of dreams has been observed in clinical studies on patients with narcolepsy-cataplexy (NC), a neurological disorder characterized by an altered sleep architecture. Laboratory studies have shown that dream experiences developed during 1st-rapid eye movement (REM) sleep by NC patients are longer and m...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2009.10.021

    authors： Mazzetti M,Bellucci C,Mattarozzi K,Plazzi G,Tuozzi G,Cipolli C

    更新日期：2010-01-15 00:00:00

  • Lateral habenula as a link between dopaminergic and serotonergic systems contributes to depressive symptoms in Parkinson's disease.

    abstract：:Degeneration of substantia nigra dopaminergic neurons is a key pathological change of Parkinson's disease (PD), and its motor consequences have been widely recognized. Recently, mood disorders associated with PD have begun to attract a great deal of interest, however, their pathogenesis remains unclear. PD is associat...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2014.11.006

    authors： Luo XF,Zhang BL,Li JC,Yang YY,Sun YF,Zhao H

    更新日期：2015-01-01 00:00:00

  • Neuronal firing patterns during generalized penicillin epilepsy in the awake cat.

    abstract：:Single unit activity was recorded in the neocortex of awake cats during spontaneous spike wave discharges. Ongoing activity was interrupted during paroxysmal events and was replaced by (1) bursts of action potentials coincident with the EEG spike and cessation of firing during the wave, or (2) cessation of firing for ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(77)90065-x

    authors： Wray DV,Hablitz JJ

    更新日期：1977-09-01 00:00:00

  • Dopamine in the hippocampal dentate gyrus modulates spatial learning via D1-like receptors.

    abstract：:Increasing evidence supports that dopamine (DA) plays an important role in the hippocampal function via activation of D1-like receptors (D1Rs). As the entry structure of the hippocampal formation, the hippocampal dentate gyrus (DG) is critically involved in spatial learning and memory. Despite a number of studies inve...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2018.11.010

    authors： Wang F,Wan P,Wang W,Xiao B,Jin H,Jin Q

    更新日期：2019-01-01 00:00:00

  • Single unit response of neurons within the hamster suprachiasmatic nucleus to GABA and low chloride perfusate during the day and night.

    abstract：:Using the in vitro hamster hypothalamic slice preparation, the effects of GABA and 80% chloride (Cl-) reduced medium on the single unit activity of SCN neurons was investigated. GABA 10(-4) M produced inhibitory responses in 55% of the 69 SCN neurons examined. No statistically significant day-night difference was obse...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(90)90257-z

    authors： Liou SY,Albers HE

    更新日期：1990-07-01 00:00:00

  • Intrastriatal implants of fetal mesencephalic cells attenuate the increases in striatal proenkephalin mRNA observed after unilateral 6-hydroxydopamine-induced lesions of the striatum.

    abstract：:Unilateral injections of 6-hydroxydopamine (6-OHDA) cause significant bilateral increases in striatal proenkephalin (PEK) mRNA in rat brain. We have tested the possibility that implantation of fetal mesencephalic cells can normalize these changes. Two types of grafts were used: 1) embryonic day-15 mesencephalic cells ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(91)90050-t

    authors： Cadet JL,Zhu SM,Angulo JA

    更新日期：1991-11-01 00:00:00

  • Early exposure to a low dose of bisphenol A affects socio-sexual behavior of juvenile female rats.

    abstract：:Play behavior is affected by alteration of the hormonal environment during development. In fact, congenital adrenal hyperplasia or early administration of diethylstilbestrol are able to modify female play behavior in mammals. In this research, play behavior of female rats was used to explore the effects of perinatal e...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2004.11.014

    authors： Porrini S,Belloni V,Della Seta D,Farabollini F,Giannelli G,Dessì-Fulgheri F

    更新日期：2005-04-15 00:00:00

  • Imunoreactivity of zinc transporter 7 (ZNT7) in mouse dorsal root ganglia.

    abstract：:In the present study, we showed for the first time the localization of ZNT7 immunoreactivity in the mouse dorsal root ganglion (DRG) by means of immunohistochemistry and confocal laser scanning microscopy. Our results revealed that ZNT7 immunoreactivity was abundantly expressed in the nerve cells of the mouse DRG. Str...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2007.06.022

    authors： Zhang L,Chi ZH,Ren H,Rong M,Dahlstrom A,Huang L,Wang ZY

    更新日期：2007-09-28 00:00:00

  • Medullary cells of origin of physiologically identified cardiac nerves in the dog.

    abstract：:Individual cardiac nerves from which stimulation elicited cardioinhibition (bradycardia and negative inotropism) were identified in 24 of 38 dogs. Subsequently, 3-25 microliters of 30% horseradish peroxidase (HRP) were injected into an identified cardiac nerve. After a 3-day survival period, the medulla oblongata was ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(82)90073-9

    authors： Hopkins DA,Armour JA

    更新日期：1982-04-01 00:00:00

  • Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis.

    abstract：:The role of several hippocampal innervations in the sensitivity to barbital-induced narcosis was studied in selected mice strains. The outbred and inbred mouse strains HS/lgb, SABRA/HUC, C57BL, CBA/LAC, and BALB/c were tested for barbital-induced sleep (315 mg/kg). The relatively short sleeping HS/lbg (HS) and the lon...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(95)00077-r

    authors： Yanai J,Pick CG

    更新日期：1995-01-01 00:00:00

  • Electrophysiological correlates among the radial nerve, the caudate and the entopeduncular nuclei in cats.

    abstract：:The entopeduncular nucleus (EPN), as the medial part of the globus pallidum, has been considered the efferent structure of the striatum. Based on this, we decided to study its possible somatosensory projections and the electrophysiological relationship with the caudate nucleus (CN). Radial nerve stimulation produced e...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(81)80050-0

    authors： Saavedra de Camargo B,Brust-Carmona H,Roig JA

    更新日期：1981-03-01 00:00:00

  • Developmental neurotoxicity of low dose diazinon exposure of neonatal rats: effects on serotonin systems in adolescence and adulthood.

    abstract：:The developmental neurotoxicity of organophosphate pesticides targets serotonin (5HT) systems, which are involved in emotional and appetitive behaviors. We exposed neonatal rats to daily doses of diazinon on postnatal days 1-4, using doses (0.5 or 2mg/kg) spanning the threshold for barely-detectable cholinesterase inh...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2007.10.008

    authors： Slotkin TA,Ryde IT,Levin ED,Seidler FJ

    更新日期：2008-03-28 00:00:00

  • Vasoactive intestinal peptide modulates luteinizing hormone subunit gene expression in the anterior pituitary in female rat.

    abstract：:The direct monosynaptic pathway which exists between vasoactive intestinal peptide (VIP) and GnRH neurons in the hypothalamic preoptic area provides a neuroanatomical background for the modulatory effects of VIP exerted on GnRH neurons activity. Though central microinjection of VIP revealed its involvement in the modu...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2005.07.007

    authors： Gajewska A,Wolińska-Witort E,Kochman K

    更新日期：2005-10-30 00:00:00

  • Factors controlling adrenal weight and corticosterone secretion in male rats as revealed by median eminence lesions and pharmacological alteration of prolactin secretion.

    abstract：:To determine whether or not prolactin, as well as ACTH, was involved in the control of adrenal weight and steroid release, lesions in the median eminence which had previously resulted in impaired steroid release and atrophy of the adrenal were placed in animals in which the plasma prolactin was allowed to rise as a re...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(87)90066-9

    authors： Marubayashi U,McCann SM,Antunes-Rodrigues J

    更新日期：1987-11-01 00:00:00