当前位置： SCI文献检索 > BRAIN RESEARCH BULLETIN期刊下所有文献 > Organization of GABA and GABA-transaminase containing neurons in the gustatory zone of the nucleus of the solitary tract.

Organization of GABA and GABA-transaminase containing neurons in the gustatory zone of the nucleus of the solitary tract.

Abstract：

:Previous cytoarchitectural and electron micrographic studies have indicated that the gustatory zone of the nucleus of the solitary tract (NST) may contain local circuit neurons. It is known that neurons of the caudal "visceroceptive" NST contain GABA, glutamic acid decarboxylase (EC 4.1.1.15), and GABA-transaminase (GABA-T; 4-aminobutyrate: 2-oxoglutarate aminotransferase; EC 2.6.1.19). The present study was conducted to determine whether or not neurons in the gustatory zone of the NST of rat contain GABA and the principle degradative enzyme of GABA, GABA-T. Transganglionic transport of horseradish peroxidase (HRP) was used to identify chorda tympani (CT) nerve terminal fields. Immunohistochemical studies were combined with transport experiments to evaluate the organization of GABA immunoreactive neurons in CT terminal fields. Results show that GABA immunoreactive neurons and puncta are located within CT terminal fields. These neurons evince small ovoid morphologies resembling Golgi interneurons, and comprise an average of 18% of total neurons in CT terminal fields. Independent histochemical studies reveal that approximately 82% of GABA immunoreactive neurons within CT terminal fields exhibit GABA-T activity. Retrograde transport of HRP was used in additional studies to evaluate whether or not axons of putative GABAergic neurons project to the second-order central gustatory relay located in the caudal parabrachial nucleus (PBNc), to the caudal NST, or to regions surrounding the rostral or caudal NST. Combined studies indicate that GABA immunoreactive neurons in the gustatory NST do not project axons to the PBNc, to the caudal NST, or to regions adjacent to the rostral or caudal NST.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Lasiter PS,Kachele DL

doi

10.1016/0361-9230(88)90202-x

subject

Has Abstract

pub_date

1988-10-01 00:00:00

pages

623-36

issue

4

eissn

0361-9230

issn

1873-2747

pii

0361-9230(88)90202-X

journal_volume

21

pub_type

杂志文章

相关文献

BRAIN RESEARCH BULLETIN文献大全
  • Monkey P3 in an "oddball" paradigm: pharmacological support for multiple neural sources.

    abstract：:Two experiments examined the effects of the alpha-2 antagonist L657,743 on monkey electroencephalographic (EEG) and event-related potential (ERP) activity following auditory and visual stimuli. In the first experiment, EEG was recorded before and after the administration of a saline placebo or L657,743 (0.01, 0.05 mg/...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(93)90142-x

    authors： Pineda JA,Westerfield M

    更新日期：1993-01-01 00:00:00

  • Lower GABAA receptor binding in the amygdala and hypothalamus of spontaneously hypertensive rats.

    abstract：:The central GABAergic system is associated with normal blood pressure regulation, but the role of GABA receptors in genetic hypertension remains unclear. This study was conducted to investigate GABAA receptor binding in several brain regions of spontaneously hypertensive (SHR) rats during development of hypertension. ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(94)00164-v

    authors： Kunkler PE,Hwang BH

    更新日期：1995-01-01 00:00:00

  • Protective effects of trans-2, 4-dimethoxystibene on cognitive, impairments induced by Abeta(25-35) in, hypercholesterolemic rats.

    abstract：:Trans-2, 4-dimethoxystibene (S3) is a synthetic stilbenes. In the present study, S3 was investigated to assess its neuroprotective effect against the toxicity induced by Abeta(25-35) in hypercholesterolemic rats. Rats were fed with hypercholesterolemic chow for six weeks, and then received a single intracerebroventric...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2010.04.016

    authors： Ruan CJ,Li Z,Zhang L,Chen DH,Du GH,Sun L

    更新日期：2010-07-30 00:00:00

  • Neuron transplantation into mice hippocampus alters sensitivity to barbital narcosis.

    abstract：:The role of several hippocampal innervations in the sensitivity to barbital-induced narcosis was studied in selected mice strains. The outbred and inbred mouse strains HS/lgb, SABRA/HUC, C57BL, CBA/LAC, and BALB/c were tested for barbital-induced sleep (315 mg/kg). The relatively short sleeping HS/lbg (HS) and the lon...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(95)00077-r

    authors： Yanai J,Pick CG

    更新日期：1995-01-01 00:00:00

  • Evidence that nitric oxide production increases gamma-amino butyric acid permeability of blood-brain barrier.

    abstract：:Blood-brain barrier permeability (BBB) to the inhibitory neurotransmitter gamma-amino butyric acid (GABA) was studied in rats following intraperitoneal (i.p) injections of GABA alone and in combination with L-Arginine (L-Arg). Administration of GABA (600 mg/kg body weight [b. wt.]) alone increased brain GABA concentra...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(01)00755-9

    authors： Shyamaladevi N,Jayakumar AR,Sujatha R,Paul V,Subramanian EH

    更新日期：2002-01-15 00:00:00

  • Effects of 14-methoxymetopon, a potent opioid agonist, on the responses to the tail electric stimulation test and plus-maze activity in male rats: neuroendocrine correlates.

    abstract：:We have studied the effects of 14-methoxymetopon (HS 198), a potent opioid agonist, on the responses to the tail electric stimulation test and plus-maze activity of adult male rats. The prototype mu agonist morphine was used as the drug of reference. Besides we addressed the effects of HS 198 on the serum corticostero...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(01)00760-2

    authors： Urigüen L,Fernández B,Romero EM,De Pedro N,Delgado MJ,Guaza C,Schmidhammer H,Viveros MP

    更新日期：2002-03-15 00:00:00

  • Task-dependent differences in corticobulbar excitability of the submental motor projections: Implications for neural control of swallowing.

    abstract：:It has been suggested that the primary motor cortex plays a substantial role in the neural circuitry that controls swallowing. Although its role in the voluntary oral phase of swallowing is undisputed, its precise role in motor control of the more reflexive, pharyngeal phase of swallowing is unclear. The contribution ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2010.11.006

    authors： Doeltgen SH,Ridding MC,Dalrymple-Alford J,Huckabee ML

    更新日期：2011-01-15 00:00:00

  • Bovine pineal antireproductive tripeptide binds to luteinizing hormone-releasing hormone: a model for peptide modulation by sequence specific peptide interactions?

    abstract：:We report results of chromatographic, pH titration and nuclear magnetic resonance (NMR) spectroscopy studies demonstrating that the bovine pineal antireproductive tripeptide, Thr-Ser-Lys (BPART), binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5 (His-Trp-Ser-Tyr). BPART and LHRH hav...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(86)90219-4

    authors： Root-Bernstein RS,Westall FC

    更新日期：1986-10-01 00:00:00

  • Magnetic resonance imaging studies of the brains of anesthetized rats treated with manganese chloride.

    abstract：:An understanding of the distribution of manganese ions in the brain is of interest in connection with the development of an understanding of the neurotoxicity of this element. Information about the time dependent biodistribution of manganese ions in the brains of intact rats subsequent to single IP injections of MnCl2...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(89)90152-4

    authors： London RE,Toney G,Gabel SA,Funk A

    更新日期：1989-09-01 00:00:00

  • Spinal projections from the nucleus locus coeruleus and nucleus subcoeruleus in the cat and monkey as demonstrated by the retrograde transport of horseradish peroxidase.

    abstract：:The rostral pons of the cat and rhesus monkey were examined for the presence of labeled cells following injections of horseradish peroxidase (HRP) into the lumbar spinal cord. Labeled cells were found in the ipsilateral dorsolateral pontine tegmentum and in the contralateral ventrolateral pontine reticular formation. ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(76)90072-1

    authors： Hancock MB,Fougerousse CL

    更新日期：1976-03-01 00:00:00

  • Inhibition of fatty acid amide hydrolase (FAAH) reduces spinal nociceptive responses and expression of spinal long-term potentiation (LTP).

    abstract：:Fatty acid amide hydrolase (FAAH) is an enzyme that metabolizes endocannabinoids and fatty acid amides possibly linked to activation of the opioid system. To examine how this enzyme affects spinal signalling, electrophysiological recordings in the dorsal horn and qPCR on dorsal horn tissue following systemic administr...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2011.11.009

    authors： Eriksen GS,Jacobsen LM,Mahmood A,Pedersen LM,Gjerstad J

    更新日期：2012-02-10 00:00:00

  • Near-infrared laser illumination transforms the fluorescence absorbing X-Gal reaction product BCI into a transparent, yet brightly fluorescent substance.

    abstract：:The beta-galactosidase protein generated by the bacterial LacZ gene is widely used to map gene expression patterns. The ease of its use is only rivaled by green fluorescent protein, which can be used in combination with various other procedures such as immunocytochemistry, flow cytometry, or tract tracing. The beta-ga...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2005.11.007

    authors： Matei VA,Feng F,Pauley S,Beisel KW,Nichols MG,Fritzsch B

    更新日期：2006-06-15 00:00:00

  • Sigma (12-15 Hz) and delta (0.3-3 Hz) EEG oscillate reciprocally within NREM sleep.

    abstract：:Sleep EEG in the sigma and delta frequency bands was subjected to spectral analysis in 8 normal young adults. In each subject, power density of sigma and delta oscillated reciprocally during NREM sleep, confirming an observation made initially with period/amplitude analysis. In REM sleep, power density for both freque...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(91)90286-s

    authors： Uchida S,Maloney T,March JD,Azari R,Feinberg I

    更新日期：1991-07-01 00:00:00

  • Hippocampal theta activity in the acute precollicular rat.

    abstract：:In eleven acute precollicular rats, cortical and hippocampal EEG activity was recorded. Hippocampal theta activity of low frequency (mean 4.5 c/sec) was found in nine rats and in four occupied above 50% of the recording time. In contrast, in the cortex the synchronized EEG activity dominated. The electrical stimulatio...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(89)90006-3

    authors： Gottesmann C,Gandolfo G,Zernicki B

    更新日期：1989-06-01 00:00:00

  • The conduction velocity and central projections of retinofugal fibers in the rabbit.

    abstract：:IN anesthetized and paralyzed rabbits, action potentials were elicited antidromically following electrical stimulation of optic tract terminals at the geniculate level (LGN). The conduction velocity spectrum extended from 7 m.s-1 to 34 m.s-1. The distribution of conduction velocities indicated four major modes at 10, ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(80)90207-5

    authors： Molotchnikoff S,Lessard I

    更新日期：1980-11-01 00:00:00

  • Molecular and cellular mechanisms of opiate action: studies in the rat locus coeruleus.

    abstract：:We have studied the molecular and cellular mechanisms underlying the acute and chronic effects of opiate on neurons of the rat locus coeruleus (LC). Acutely, opiates inhibit LC neurons by activating K+ channels and inhibiting a novel sodium-dependent inward current. Both of these actions are mediated via pertussis tox...

    journal_title：Brain research bulletin

    pub_type： 杂志文章,评审

    doi：10.1016/0361-9230(94)90166-x

    authors： Nestler EJ,Alreja M,Aghajanian GK

    更新日期：1994-01-01 00:00:00

  • Developmental disruptions and behavioral impairments in rats following in utero RNAi of Dyx1c1.

    abstract：:Developmental malformations of cortex have been shown to co-occur with language, learning, and other cognitive deficits in humans. Rodent models have repeatedly shown that animals with such developmental malformations have deficits related to auditory processing and learning. More specifically, freeze-lesion induced m...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2006.11.005

    authors： Threlkeld SW,McClure MM,Bai J,Wang Y,LoTurco JJ,Rosen GD,Fitch RH

    更新日期：2007-03-15 00:00:00

  • Immunohistochemical estimation of brain choline acetyltransferase and somatostatin related to the impairment of avoidance learning induced by thiamine deficiency.

    abstract：:We have found that thiamine-deficient (TD) rats show significant impairment of avoidance learning on the 25th day after the start of TD diet, as measured by passive-avoidance task. Administration of physostigmine (0.1 mg/kg, i.p.) from the 14th day after the start of TD diet improved the impairment of avoidance learni...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(00)00248-3

    authors： Nakagawasai O,Tadano T,Hozumi S,Tan-No K,Niijima F,Kisara K

    更新日期：2000-06-01 00:00:00

  • NMDA-glutamatergic activation of the ventral tegmental area induces hippocampal theta rhythm in anesthetized rats.

    abstract：:Glutamate afferents reaching the ventral tegmental area (VTA) affect dopamine (DA) cells in this structure probably mainly via NMDA receptors. VTA appears to be one of the structures involved in regulation of hippocampal theta rhythm, and this work aimed at assessing the role of glutamatergic activation of the VTA in ...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2014.06.001

    authors： Matulewicz P,Orzeł-Gryglewska J,Kuśmierczak M,Jurkowlaniec E

    更新日期：2014-08-01 00:00:00

  • Serotonin 1B receptor regulation after dorsal subiculum deafferentation.

    abstract：:The subiculum may be the key structure in the transfer of relevant processed information from the hippocampal formation to cortical areas. We investigated the location of the serotonin 1B receptor (5-HT1B) in the hippocampus with the specific ligand serotonin-O-carboxymethyl-glycyl[125I]tyrosinamide in rat brain secti...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(95)00066-n

    authors： Aït Amara D,Segu L,Naïli S,Buhot MC

    更新日期：1995-01-01 00:00:00

  • Isolation of glycosaminoglycans from basement membranes of brain microvessels.

    abstract：:Although the core protein of a heparan sulfate proteoglycan has been detected in brain microvessel basement membranes by immunoperoxidase staining, cytochemical evidence of a glycosaminoglycan component, in the form of discrete staining with ruthenium red, is not found. To resolve this discrepancy, we examined the gly...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(88)90005-6

    authors： Schmidley JW,Blue P

    更新日期：1988-01-01 00:00:00

  • Molecular cloning and altered expression of Pbx4 in the spinal cord during tail regeneration of Gekko japonicus.

    abstract：:Transcription factor Pbx4 is recruited to form dimeric or trimeric complexes with Hox and/or Meis homeodomain proteins and participates in patterning the hindbrain and retina during vertebrate CNS development. We characterized a Pbx4 cDNA isolated from a Gekko japonicus brain and spinal cord cDNA library. Northern blo...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2009.08.010

    authors： Wang Y,Jiang X,Liu Y,Gu X,Huan Y,Ren L,Ding F,Gu X

    更新日期：2009-12-16 00:00:00

  • The effect of callosotomy on testicular steroidogenesis in hemiorchidectomized rats: a pituitary-independent regulatory mechanism.

    abstract：:In recent years, increasing number of data indicate that cerebral structures exert a direct, pituitary-independent, neural regulatory action on the endocrine glands. In addition, both experimental and clinical observations indicate functional asymmetry of the control system. Therefore, the objective of the present stu...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/s0361-9230(00)00337-3

    authors： Banczerowski P,Csaba Z,Csernus V,Gerendai I

    更新日期：2000-09-15 00:00:00

  • Downregulation of LncRNA Gas5 inhibits apoptosis and inflammation after spinal cord ischemia-reperfusion in rats.

    abstract：:Spinal cord ischemia-reperfusion injury(SCII)affects nerve function through many mechanisms, which are complex and not fully understood. Recently, accumulating evidence has indicated that long noncoding RNAs (lncRNAs) play an increasingly important role in SCII. We investigated the role of lncRNA growth arrest-specifi...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2020.12.005

    authors： Zhang Z,Li X,Chen F,Li Z,Wang D,Ren X,Ma H

    更新日期：2020-12-11 00:00:00

  • Effect of mild and chronic neonatal hypothyroidism on sensory information processing in a rodent model: A behavioral and electrophysiological study.

    abstract：:Thyroid hormones are essential for neonatal brain development. It is well established that absence of thyroid hormones during critical periods of development can alter sensory functions such as visual and auditory processing, but there are few studies on rat somatosensory system development at mild, long-term, and irr...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2019.11.015

    authors： Afarinesh MR,Shafiei F,Sabzalizadeh M,Haghpanah T,Taheri M,Parsania S,Golshan F,Sheibani V

    更新日期：2020-02-01 00:00:00

  • Cysteamine effects on somatostatin, catecholamines, pineal NAT and melatonin in rats.

    abstract：:The thiol reagent cysteamine was administered to adult male rats with the aim of investigating its effect on different neural and pineal components. As expected, immunoreactive somatostatin decreased in the median eminence (ME) (p less than 0.05) and gastric antrum (p less than 0.05) after cysteamine; however, no sign...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(86)90051-1

    authors： Webb SM,Champney TH,Steger RW,Vaughan MK,Reiter RJ

    更新日期：1986-03-01 00:00:00

  • Calmodulin regulates fast axonal transport of squid axoplasm organelles.

    abstract：:The role of calmodulin (CaM) in organelle motility (fast axonal transport) in the axoplasm of the squid giant axon was evaluated directly using video-enhanced microscopy. Addition of 6 microM CaM to extruded squid axoplasm produced a 2.6-fold increase in the number of organelles moving per minute per unit area of axop...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(94)00256-8

    authors： Rivera DT,Langford GM,Weiss DG,Nelson DJ

    更新日期：1995-01-01 00:00:00

  • Bradykinesia in patients with Parkinson's disease having levodopa-induced dyskinesias.

    abstract：:We investigated the likelihood that bradykinesia coexisted with levodopa-induced dyskinesias (LID) in 10 dyskinetic Parkinson's disease patients (DPD). Their motor performance was compared to that of 10 age/gender-matched non-dyskinetic patients (NDPD) and 10 healthy controls. Whole-body movement (WBM) and rapid alter...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2006.02.015

    authors： Ghassemi M,Lemieux S,Jog M,Edwards R,Duval C

    更新日期：2006-05-15 00:00:00

  • Up-regulated microRNA-218-5p ameliorates the damage of dopaminergic neurons in rats with Parkinson's disease via suppression of LASP1.

    abstract：OBJECTIVE:Parkinson's disease (PD) is a frequent degenerative disease of the nervous system with undefined pathogenesis. This study explored the protective effect of microRNA (miR)-218-5p on dopaminergic neuron injury in substantia nigra (SN) of rats with PD through the regulation of LIM and SH3 domain protein 1 (LASP1...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/j.brainresbull.2020.10.019

    authors： Ma X,Zhang H,Yin H,Geng S,Liu Y,Liu C,Zhao J,Liu Y,Wang X,Wang Y

    更新日期：2021-01-01 00:00:00

  • Plasma gonadotropin, prolactin levels and hypothalamic tyrosine hydroxylase activity following intraventricular bombesin and secretin in ovariectomized conscious rats.

    abstract：:Plasma gonadotropins, prolactin and hypothalamic tyrosine hydroxylase (TH) activity were evaluated at 15 and 30 min after third ventricular injection of bombesin at doses of 100 or 1000 ng and secretin at doses of 1000 and 5000 ng in ovariectomized (OVX) unanesthetized rats. Bombesin had no effect on plasma gonadotrop...

    journal_title：Brain research bulletin

    pub_type： 杂志文章

    doi：10.1016/0361-9230(83)90053-9

    authors： Babu GN,Vijayan E

    更新日期：1983-07-01 00:00:00