Abstract:
:In eleven acute precollicular rats, cortical and hippocampal EEG activity was recorded. Hippocampal theta activity of low frequency (mean 4.5 c/sec) was found in nine rats and in four occupied above 50% of the recording time. In contrast, in the cortex the synchronized EEG activity dominated. The electrical stimulation of the posterior hypothalamus induced the theta rhythm, or increased its frequency. The large amounts of theta activity in some rats suggests that the forebrain theta pacemakers, partly modulated by the posterior hypothalamus, are released from brain stem inhibitory influences.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Gottesmann C,Gandolfo G,Zernicki Bdoi
10.1016/0361-9230(89)90006-3subject
Has Abstractpub_date
1989-06-01 00:00:00pages
959-62issue
6eissn
0361-9230issn
1873-2747pii
0361-9230(89)90006-3journal_volume
22pub_type
杂志文章abstract::We studied mitochondria in the satellite cell sheaths which envelope the spinal ganglion neurons of rabbits aged 12, 42, and 79 months. While the mean cytoplasmic volume of satellite cell sheaths did not change significantly with age, the mean percentage of cytoplasmic volume occupied by mitochondria decreased with ag...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(03)00101-1
更新日期:2003-07-15 00:00:00
abstract::Cranioplasty is a challenge to neurosurgeons, especially considering protection of intracranial contents. In recent years, material choice for cranioplasty is still controversial, which brings complexity to this seemingly straightforward procedure. PEEK, a tough, rigid, biocompatible material, has been used more recen...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2019.08.010
更新日期:2019-11-01 00:00:00
abstract::In precollicular decerebrate cats, the vestibulospinal reflex (VSR) was intermittently recorded from the triceps brachii during sinusoidal roll tilt of the whole animal (at 0.15 Hz, +/- 10 degrees), leading to selective stimulation of labyrinth receptors. This reflex, tested during and after a 3-h period of sustained ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(94)90156-2
更新日期:1994-01-01 00:00:00
abstract::Nagase genetically analbuminemic rats (NAR) were run to fatigue. Administration of branched chain amino acids (BCAA) before exhaustive exercise, resulted in a post-fatigue decreased tryptophan uptake (-22%, p < 0.05) and 5-hydroxytryptophan (5-HTP) uptake (-29%, p < 0.01) into the synaptosomes isolated from the striat...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(99)00276-2
更新日期:2000-05-01 00:00:00
abstract::Intra-arterial administration of papaverine has been revealed to cause an increase in the blood-brain tumor barrier (BTB) permeability. The exact mechanism of papaverine opening the BTB in chemotherapy of malignant cerebral tumors, however, has not been well described. We used a rat brain glioma (C6) model for studyin...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2010.08.009
更新日期:2010-11-20 00:00:00
abstract::Neurochemical analysis of norepinephrine and serotonin with high performance liquid chromatography with electrochemical detection (LCEC) in several microdissected central autonomic nuclei of 4 week old and 16 week old spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto rats (WKY), and control normotensive...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(84)90095-9
更新日期:1984-09-01 00:00:00
abstract::Cats pretreated with morphine (5 mg/kg, IP) received naloxone into the area of the locus coeruleus (LC) or the area of the substantia nigra (SN). The LC-treated animals stopped the morphine-induced stereotyped behavior and showed normal but hyperactive behavior. The SN-treated animals, however, ceased their movements ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(79)80006-4
更新日期:1979-05-01 00:00:00
abstract::The objective of this study was to determine the organization of coactivation in the arm and shoulder muscles. Normal human subjects made alternate movements of a joint in the horizontal plane, either adduction-abduction of the second finger and shoulder, ulnar-radial deviation of the wrist, or extension-flexion of th...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(02)00952-8
更新日期:2003-02-15 00:00:00
abstract::Mechanisms underlying shock-induced conditioned fear - a paradigm frequently used to model posttraumatic stress disorder, PTSD - are usually studied shortly after shocks. Some of the brain regions relevant to conditioned fear were activated in all the c-Fos studies published so far, but the overlap between the activat...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2012.04.001
更新日期:2012-07-01 00:00:00
abstract::To investigate the direct actions of neurotropin (NSP, a nonproteinaceous extract from inflamed skin of rabbits which is in therapeutic use), intracellular recordings were made from neurons of the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LHA) in slices of guinea pig brain. In the VMH, NSP...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(92)90144-m
更新日期:1992-12-01 00:00:00
abstract::We examined some developmental and behavioral sequelae of exposing Binghamton Heterogeneous Stock (HET) mice to a 0.5% aqueous lead acetate solution (as the only available fluid source) for either none, one, two, or three generations. Lead exposure, regardless of generation, resulted in decreased body weight and a del...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(94)00228-s
更新日期:1995-01-01 00:00:00
abstract::An animal with an unimpaired "reference" memory can distinguish between alternatives that belong to a rewarded set and those that are unrewarded. An animal with an unimpaired "working" memory can distinguish between alternatives where it has been rewarded (e.g., food has been eaten and not replaced) and those where it...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(81)90086-1
更新日期:1981-08-01 00:00:00
abstract::A method is described for the removal of discrete areas of the monkey brain. A detailed mapping of norepinephrine, dopamine, choline acetyltransferase and glutamic acid decarboxylase in the newborn and pubescent monkey brain is presented. ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(80)80016-5
更新日期:1980-07-01 00:00:00
abstract::Trisomy of the whole or distal part of human chromosome 21 (HSA 21) (Ts21) results in Down Syndrome (DS), which is characterized in part by mental retardation and associated neurological abnormalities. Structural abnormalities observed frequently include reduced brain weight, decreased number and depth of sulci in the...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/0361-9230(86)90074-2
更新日期:1986-06-01 00:00:00
abstract::Efferent projections from the basal forebrain to the cat's cerebral cortex were traced with the retrograde horseradish peroxidase technique. Different areas of the cerebral cortex of 51 cats were injected with small amounts of horseradish peroxidase. The entire basal forebrain was screened for labeled neurons. Followi...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(84)90165-5
更新日期:1984-05-01 00:00:00
abstract::Mounting clinical and experimental evidence suggests the gut-brain interplay as a novel important paradigm in translational neuroscience, including the critical role for gut microbiota in modulating brain development and behavior, as well as neuroimmune and neuroendocrine responses. Animal models are an indispensable ...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2019.03.003
更新日期:2019-05-01 00:00:00
abstract::Thyroid-stimulating hormone (TSH) stimulates the synthesis and release of thyroid hormones including triiodothyronine (T3) and thyroxine (T4). Semiquantitative analyses using northern blot and in situ hybridization suggested that TSH gene transcription is upregulated under conditions of hypothyroidism. However, no qua...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2007.06.004
更新日期:2007-09-14 00:00:00
abstract::Induction of expression of immediate-early gene c-Fos in the striatum is a common effect of many drugs of abuse, including morphine. Previous studies have shown that the morphine-mediated c-Fos response is attenuated by antagonists of the N-methyl-D-aspartate (NMDA) subtype of glutamate receptor. Other evidence sugges...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/s0361-9230(00)00451-2
更新日期:2001-01-15 00:00:00
abstract::Anxiety disorders and nicotine use are significant contributors to global morbidity and mortality as independent and comorbid diseases. Early-life stress, potentially via stress-induced hypothalamic-pituitary-adrenal axis (HPA) dysregulation, can exacerbate both. However, little is known about the factors that predisp...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2017.08.001
更新日期:2018-04-01 00:00:00
abstract::Subpallial structures are highly conserved across the different vertebrate species. They are instrumental in the neural processing relevant to adaptive learning, decision making, motivation and behavioural strategies. Of the striatal regions, our attention has been focussed on the medial and ventral striatum (MSt), no...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2008.02.025
更新日期:2008-06-15 00:00:00
abstract::After injecting a mixture of tritiated amino acids into various regions of the frontal cortices of cats, autoradiograms of the mesodiencephalic junctional region were processed. When the injections were placed in the lateral part of the motor area of the hand or arm regions, silver grains were manifested in the nucleu...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(83)90149-1
更新日期:1983-04-01 00:00:00
abstract::Various hypotheses are reviewed concerning the mechanisms of feeding induced by insulin or 2DG. New data are presented to show that elevated plasma ketone levels are not sufficient to suppress 2DG feeding, suggesting that nourishment of the brain either does not occur or is not sufficient to stop 2DG feeding. We find ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(85)90111-x
更新日期:1985-06-01 00:00:00
abstract::The effects of intracarotidly injected neuropeptide Y (NPY; 0.1 micrograms/kg) on the local cerebral blood volume (CBV) and blood flow (CBF) in the parieto-temporal cortex were examined by the photoelectric method in 17 anesthetized cats. CBV reflects the cumulative crosssectional area of the cerebral microvascular be...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(93)90107-m
更新日期:1993-01-01 00:00:00
abstract::The present study in piglets was designed to examine cerebrovascular effects of tumor necrosis factor-alpha (TNF alpha) and potential mechanisms involved. Anesthetized new-born pigs with closed cranial windows implanted were used. Effects of nitric oxide synthase (NOS) inhibitors, NG-nitro-L-arginine (L-NNA) and amino...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(95)02142-6
更新日期:1996-01-01 00:00:00
abstract::Thyroid hormones are essential for neonatal brain development. It is well established that absence of thyroid hormones during critical periods of development can alter sensory functions such as visual and auditory processing, but there are few studies on rat somatosensory system development at mild, long-term, and irr...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2019.11.015
更新日期:2020-02-01 00:00:00
abstract::Although interleukin-1β (IL-1β) is a prototypical pro-inflammatory cytokine, the specific mechanisms underlying the role of its cognate receptor, the interleukin-1 receptor (IL-1R) in peripheral sensitization remain to be investigated. Since emerging evidence in the literature indicates that IL-1β can modulate membran...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2017.01.019
更新日期:2017-04-01 00:00:00
abstract::Mutations in PLA2G6, which encodes calcium-independent phospholipase A(2) group VIA (iPLA2-VIA), underlie the autosomal recessive disorder infantile neuroaxonal dystrophy (INAD). INAD typically presents in the first year of life, and leads to optic atrophy and psychomotor regression. We have examined PLA2G6 expression...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2010.08.011
更新日期:2010-11-20 00:00:00
abstract::Behavioral abnormalities have been reported in young and adult animals exposed to benzodiazepines prenatally. The presence of neurochemical alterations in the GABAergic system after prenatal benzodiazepine exposure was assessed in a chick model which avoids prenatal and postnatal maternal effects. The GABAA receptor c...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/0361-9230(89)90143-3
更新日期:1989-09-01 00:00:00
abstract::The alpha-2 adrenoreceptor agonist clonidine in low dose inhibits the release of noradrenaline and aggravates absence seizures. The present study examines properties of two types of spike-wave discharges (SWD) in a genetic model of absence epilepsy, the WAG/Rij rats. After reduction of noradrenergic neurotransmission ...
journal_title:Brain research bulletin
pub_type: 杂志文章
doi:10.1016/j.brainresbull.2004.11.004
更新日期:2005-01-30 00:00:00
abstract::Cerebral malaria (CM) is the severe neurological complication associated with Plasmodium falciparum infection. In clinical settings CM is predominantly characterized by fever, epileptic seizures, and asexual forms of parasite on blood smears, coma and even death. Cognitive impairment in the children and adults even af...
journal_title:Brain research bulletin
pub_type: 杂志文章,评审
doi:10.1016/j.brainresbull.2020.01.020
更新日期:2020-04-01 00:00:00