Abstract：
:In recent years, increasing number of data indicate that cerebral structures exert a direct, pituitary-independent, neural regulatory action on the endocrine glands. In addition, both experimental and clinical observations indicate functional asymmetry of the control system. Therefore, the objective of the present study was to study the effect of callosotomy on testicular steroidogenesis and serum gonadotrop concentrations in rats subjected to left- or right-sided orchidectomy. In animals underwent callosotomy plus left-sided orchidectomy the basal testosterone secretion in vitro of the remaining (right) testis was significantly higher than that of intact controls, and of rats subjected to sham surgery plus left orchidectomy. In contrast, either sham operation or callosotomy plus right-sided orchidectomy did not interfere with testicular steroidogenesis. Sham surgery or callosotomy plus left orchidectomy induced a significant rise in serum follicle-stimulating hormone concentration while right orchidectomy combined either with sham surgery or callosotomy did not alter this parameter. There was no statistically significant difference between experimental groups in serum testosterone and luteinizing hormone concentrations. The results indicate the involvement of the corpus callosum in a pituitary-independent neural control of testicular steroidogenesis. The data further suggest a different response in steroidogenesis of the left and the right testis following hemicastration and callosotomy.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Banczerowski P,Csaba Z,Csernus V,Gerendai Idoi
10.1016/s0361-9230(00)00337-3keywords:
subject
Has Abstractpub_date
2000-09-15 00:00:00pages
227-32issue
2eissn
0361-9230issn
1873-2747pii
S0361-9230(00)00337-3journal_volume
53pub_type
杂志文章abstract：:Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valua...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
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journal_title：Brain research bulletin
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更新日期：2019-10-01 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
doi：10.1016/0361-9230(83)90211-3
更新日期：1983-06-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2015.08.001
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pub_type： 杂志文章
doi：10.1016/j.brainresbull.2008.06.008
更新日期：2008-09-30 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2013.09.008
更新日期：2013-10-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(85)90059-0
更新日期：1985-07-01 00:00:00
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更新日期：2011-01-15 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/0361-9230(91)90275-o
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pub_type： 杂志文章
doi：10.1016/s0361-9230(80)80013-x
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pub_type： 杂志文章
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journal_title：Brain research bulletin
pub_type： 杂志文章
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(87)90021-9
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journal_title：Brain research bulletin
pub_type： 杂志文章
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journal_title：Brain research bulletin
pub_type： 杂志文章,评审
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更新日期：2019-02-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2018.02.019
更新日期：2018-05-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2013.11.008
更新日期：2014-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2017.02.001
更新日期：2018-01-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(98)00050-1
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(02)00753-0
更新日期：2002-05-01 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2010.12.005
更新日期：2011-04-05 00:00:00
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journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2006.05.008
更新日期：2006-07-31 00:00:00
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pub_type： 杂志文章
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