Abstract：
:Sleep EEG in the sigma and delta frequency bands was subjected to spectral analysis in 8 normal young adults. In each subject, power density of sigma and delta oscillated reciprocally during NREM sleep, confirming an observation made initially with period/amplitude analysis. In REM sleep, power density for both frequency bands was at its lowest levels. Correlation coefficients between power density of delta vs. 1/sigma for all artifact-free 20-s epochs of NREM sleep/night were highly significant for each subject. These results show that cyclic oscillation of EEG within sleep is not limited to delta frequencies. The reciprocal relation of sigma to delta holds implications for the EEG mechanisms of NREM sleep. This dynamic pattern may also prove useful for sleep stage scoring and for a finer empirical analysis of sleep in psychiatric and neurological disorders.
journal_name
Brain Res Bulljournal_title
Brain research bulletinauthors
Uchida S,Maloney T,March JD,Azari R,Feinberg Idoi
10.1016/0361-9230(91)90286-ssubject
Has Abstractpub_date
1991-07-01 00:00:00pages
93-6issue
1eissn
0361-9230issn
1873-2747pii
0361-9230(91)90286-Sjournal_volume
27pub_type
杂志文章abstract：:Early life Stress is a worldwide concern linked with development of later life neurological disorders. Early developmental age is sensitive to many prominent environmental insults like malnourishment, immune inflammation, abuse, maternal separation, alcohol and drugs. Hence, an individual during an early age encounter...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2019.02.005
更新日期：2019-04-01 00:00:00
abstract：:The loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) and the accumulation of protein inclusions (Lewy bodies) are the pathological hallmarks of Parkinson's disease (PD). PD is triggered by genetic alterations, environmental/occupational exposures and aging. However, the exact molecular mechani...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2017.03.009
更新日期：2017-07-01 00:00:00
abstract：:The effect of subarachnoid hemorrhage (SAH) on the neuropeptides and mast cells of the rat dura mater has not been reported. We examined the outcome of SAH on the rat supratentorial dura mater to determine whether dural nerves undergo effects similar to those of nerves accompanying cerebral blood vessels after SAH. Fo...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(93)90146-3
更新日期：1993-01-01 00:00:00
abstract：:The present study investigates the protective effects of electroacupuncture (EA) application on cardiac function, while simultaneously exploring the underlying neurobiological mechanisms, in rats that have experienced thoracic surgery-induced stress. Mean arterial and left intraventricular pressures were monitored as ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2012.06.008
更新日期：2012-10-01 00:00:00
abstract：:Human autopsy brain tissue is widely used to study neurodegenerative diseases such as Alzheimer's, Parkinson's and other diseases. However, when it comes to an evaluation of data obtained from such tissue, it is essential to consider potential postmortem effects on protein composition, posttranslational modification a...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2016.01.005
更新日期：2016-03-01 00:00:00
abstract：:Subcutaneous administration of the alpha 2-adrenoreceptor antagonists, yohimbine and tolazoline, at doses up to 1000 micrograms/kg, had no effect on water intake of female rats. However, when these compounds were administered SC in combination with either the beta-adrenoreceptor agonist, isoproterenol (10 to 25 microg...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(83)90083-7
更新日期：1983-01-01 00:00:00
abstract：:Promoting remyelination and/or minimizing demyelination are key therapeutic strategies under investigation for diseases and injuries like multiple sclerosis (MS), spinal cord injury, stroke, and virus-induced encephalopathy. Myelination is essential for efficacious neuronal signaling. This myelination process is origi...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2019.07.013
更新日期：2019-10-01 00:00:00
abstract：:The effects of a unilateral lesion made on the right or left side of the preoptic area (POA) or anterior hypothalamic area (AHA) made on each day of the estrous cycle, were analyzed. Ovulation rate decreased among the animals with a lesion performed on the day of estrous on the right side of POA (1/7 vs. 7/7, p < 0.05...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(94)90230-5
更新日期：1994-01-01 00:00:00
abstract：:Spinal cord ischemia-reperfusion injury(SCII)affects nerve function through many mechanisms, which are complex and not fully understood. Recently, accumulating evidence has indicated that long noncoding RNAs (lncRNAs) play an increasingly important role in SCII. We investigated the role of lncRNA growth arrest-specifi...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2020.12.005
更新日期：2020-12-11 00:00:00
abstract：:The non-adenosine nucleoside guanosine (Guo) was demonstrated to decrease quinolinic acid(QA)-induced seizures, spontaneously emerged absence epileptic seizures and lipopolysaccharide(LPS)-evoked induction of absence epileptic seizures suggesting its antiepileptic potential. It was also described previously that intra...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2016.05.001
更新日期：2016-06-01 00:00:00
abstract：:The efferent and centrifugal afferent connections of the main olfactory bulb (MOB) of the mouse were studied by orthograde and retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP). MOB projects ipsilaterally to the anterior olfactory nucleus, taenia tecta, anterior hippocampal c...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(84)90148-5
更新日期：1984-06-01 00:00:00
abstract：:Among the brain areas studied only pars distalis and pars intermedia are found to contain beta-lipotropin activating enzyme indicating the these may be the exclusive organs for a physiologically significant conversion of beta-lipotropin into beta-endorphin. beta-Endorphin inactivating enzyme is found to be rather unif...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(77)90079-x
更新日期：1977-07-01 00:00:00
abstract：:Mounting clinical and experimental evidence suggests the gut-brain interplay as a novel important paradigm in translational neuroscience, including the critical role for gut microbiota in modulating brain development and behavior, as well as neuroimmune and neuroendocrine responses. Animal models are an indispensable ...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2019.03.003
更新日期：2019-05-01 00:00:00
abstract：:Maternal immune activation during pregnancy is a risk factor for neurodevelopmental disorders, such as schizophrenia; however, a full mechanistic understanding has yet to be established. The activity of a transient cell population, the subplate neurons, is critical for the development of cortical inhibition and functi...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2017.10.006
更新日期：2017-10-01 00:00:00
abstract：:In response to the growing interest in the prosimian Microcebus murinus for studies on cerebral aging, the stereotaxic atlas of its brain was carried out in view of further anatomical, biochemical, electrophysiological, and behavioral investigations as well as for therapeutic experiments. This primate, which could be ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(97)00458-9
更新日期：1998-05-01 00:00:00
abstract：:Blood-brain barrier permeability (BBB) to the inhibitory neurotransmitter gamma-amino butyric acid (GABA) was studied in rats following intraperitoneal (i.p) injections of GABA alone and in combination with L-Arginine (L-Arg). Administration of GABA (600 mg/kg body weight [b. wt.]) alone increased brain GABA concentra...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(01)00755-9
更新日期：2002-01-15 00:00:00
abstract：:Extracellular recordings were made from 467 anti-dromically identified neurosecretory neurons and 148 non-neurosecretory neurons in the paraventricular nucleus of the hypothalamus of hemispherectomized cats under pentobarbital anesthesia. Stimulation of the dorsal, median, and pontine raphe nuclei excited 31%, 26%, an...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(92)90105-7
更新日期：1992-04-01 00:00:00
abstract：:The C57BL/6J (B6) inbred mouse strain was compared to the A/J inbred strain for motor activity in an open-field, exploration of a hole-board, motor coordination in the coat-hanger test, and spatial learning in the Morris water maze. B6 mice displayed a higher number of segment crossings in the open-field and of hole-p...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/s0361-9230(02)00782-7
更新日期：2002-06-01 00:00:00
abstract：:Long chain fatty acids (FA) and 2-monoacylglycerols (MG) are produced by lipoprotein lipase (LPL) from plasma triacylglycerols (TG) in capillaries of adipose tissue and transported to adipocytes for TG synthesis. It is widely proposed FA may be transported in cells by FA-binding protein. Mode of transport of MG has re...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/0361-9230(91)90147-c
更新日期：1991-09-01 00:00:00
abstract：:The elevated plus-maze is an animal model used to study anxiety. In a second session, rats show a reduction in the exploratory behavior even when the two sessions are separated by intervals as large as 7 days. The aim of the present study was to investigate whether the reduction in the exploratory behavior is maintain...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2010.01.007
更新日期：2010-04-05 00:00:00
abstract：:We quantitated the activity of ornithine decarboxylase (ODC) in homogenates and subcellular fractions of inner ear tissues from the rat and guinea pig and demonstrate inhibition of cochlear ODC by the aminoglycoside neomycin. Subcellular fractionation showed the enzyme associated with the post-mitochondrial supernatan...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(87)90056-6
更新日期：1987-12-01 00:00:00
abstract：:After injecting a mixture of tritiated amino acids into various regions of the frontal cortices of cats, autoradiograms of the mesodiencephalic junctional region were processed. When the injections were placed in the lateral part of the motor area of the hand or arm regions, silver grains were manifested in the nucleu...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(83)90149-1
更新日期：1983-04-01 00:00:00
abstract：:In order to test the functional significance of noradrenergic neurotransmission for brain maturation, rat pups were injected daily with clonidine from 8-21 days of postnatal life. In adulthood, single cell responses to microiontophoretically applied neurotransmitters were studied in different layers of the hippocampus...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(89)90212-8
更新日期：1989-10-01 00:00:00
abstract：:Peroxynitrite (ONOO-) is a strong biological oxidant formed by the diffusion-limited reaction of nitric oxide (NO-) and superoxide anion (O2-). It has long been theorized that peroxynitrite generation could be the cause in a number of pathological conditions ranging from atherosclerosis to inflammatory, autoimmune, he...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/j.brainresbull.2017.05.008
更新日期：2017-07-01 00:00:00
abstract：:Here we asked if insulin activation of the nucleus accumbens in vitro is reflected by an increase in (3)H-deoxyglucose ([(3)H]DG) uptake, thus subserving a new model to study molecular mechanisms of central insulin actions. Additionally, we investigated the dependence of this insulin effect on endocannabinoids and cor...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/j.brainresbull.2016.05.009
更新日期：2016-06-01 00:00:00
abstract：:A classical approach to the control of food consumption has been to assume separate mechanisms for the arousal to eat, on the one hand, and the satiation of feeding responses, on the other. The present paper is concerned with a single, and a comparatively simple, neuronal mechanism which is endowed with properties to ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(85)90008-5
更新日期：1985-10-01 00:00:00
abstract：:The nucleus reticularis gigantocellularis of the rat medulla oblongata was perfused in situ, and effects of noxious stimuli on the release of immunoreactive Met-enkephalin were examined. Formalin-induced and thermal but not mechanical stimuli increased the "tonic" release of immunoreactive Met-enkephalin from this nuc...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(84)90223-5
更新日期：1984-01-01 00:00:00
abstract：:In precollicular decerebrate cats, the vestibulospinal reflex (VSR) was intermittently recorded from the triceps brachii during sinusoidal roll tilt of the whole animal (at 0.15 Hz, +/- 10 degrees), leading to selective stimulation of labyrinth receptors. This reflex, tested during and after a 3-h period of sustained ...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(94)90156-2
更新日期：1994-01-01 00:00:00
abstract：:This study is a summary of investigations in the last decade with several collaborators on representatives of different vertebrate stocks. The results suggest that in the main vertebrate stocks (Agnathi, Chondrichthyes, Actinopterygii, Sarcopterygii-Amniotes), which had their parallel brain evolutions from the laminar...
journal_title：Brain research bulletin
pub_type： 杂志文章,评审
doi：10.1016/s0361-9230(01)00713-4
更新日期：2002-02-01 00:00:00
abstract：:This study tested for the presence of androgen receptor-immunoreactivity in somatostatin, galanin, vasopressin, corticotropin-releasing hormone, and oxytocin neurons in the rat forebrain. The brains of adult male Sprague-Dawley rats were fixed with 4% paraformaldehyde. Androgen receptor was visualized in coronal secti...
journal_title：Brain research bulletin
pub_type： 杂志文章
doi：10.1016/0361-9230(94)90117-1
更新日期：1994-01-01 00:00:00
