Sigma (12-15 Hz) and delta (0.3-3 Hz) EEG oscillate reciprocally within NREM sleep.

abstract：:Acute inflammation activates macrophages or monocytes and subsequently releases several inflammatory cytokines and reactive oxygen and nitrogen species. These proinflammatory cytokines activate astrocytes and trigger neurodegenerative diseases. In this work, we chose to address the mechanistic aspects of alpha-crystal...

journal_title：Brain research bulletin

authors： Masilamoni JG,Vignesh S,Kirubagaran R,Jesudason EP,Jayakumar R

更新日期：2005-10-15 00:00:00

abstract：:Recent studies demonstrate that activation of Ca(2+)-permeable N-methyl-D-aspartate (NMDA) receptors upregulates phosphorylation of mitogen-activated protein kinases (MAPKs) in heterologous cells and neurons. In cultured rat striatal neurons, the present work systematically evaluated the role of a number of protein ki...

journal_title：Brain research bulletin

authors： Mao LM,Tang QS,Wang JQ

更新日期：2009-03-30 00:00:00

abstract：:This paper reviews and provides new data on the relationship of the peptide content in rat dorsal root ganglion (DRG) neurons to a) the neurofilament content of the soma and b) the conduction velocities of the fibres. The latter involved intracellular recordings made in vitro followed by dye injection and immunocytoch...

journal_title：Brain research bulletin

authors： Lawson SN,Perry MJ,Prabhakar E,McCarthy PW

更新日期：1993-01-01 00:00:00

abstract：:Prenatal cocaine exposure increases mu-opioid receptor binding in dopaminergic terminal areas and enhances behavioral responsiveness to mu-opioid agonists. We investigated the influence of early postnatal cocaine treatment on in vitro mu- and delta-opioid receptor activation in male and female weanling rats. Pups rece...

journal_title：Brain research bulletin

authors： Meyer JS,Shani I,Rice D

更新日期：2000-09-15 00:00:00

abstract：:An understanding of the distribution of manganese ions in the brain is of interest in connection with the development of an understanding of the neurotoxicity of this element. Information about the time dependent biodistribution of manganese ions in the brains of intact rats subsequent to single IP injections of MnCl2...

journal_title：Brain research bulletin

authors： London RE,Toney G,Gabel SA,Funk A

更新日期：1989-09-01 00:00:00

abstract：:Direct intracellular measurements of excitability changes to injected current were made in 116 cortical neurons of awake cats following antidromic or orthodromic activation by repetitive, 1-6 Hz stimulation of the pes pedunculi. The predominant effect seen in antidromically activated cells was a transient decrease in ...

journal_title：Brain research bulletin

authors： Tzebelikos E,Woody CD

更新日期：1979-09-01 00:00:00

abstract：:Individual cardiac nerves from which stimulation elicited cardioinhibition (bradycardia and negative inotropism) were identified in 24 of 38 dogs. Subsequently, 3-25 microliters of 30% horseradish peroxidase (HRP) were injected into an identified cardiac nerve. After a 3-day survival period, the medulla oblongata was ...

journal_title：Brain research bulletin

authors： Hopkins DA,Armour JA

更新日期：1982-04-01 00:00:00

abstract：:The nucleus reticularis gigantocellularis of the rat medulla oblongata was perfused in situ, and effects of noxious stimuli on the release of immunoreactive Met-enkephalin were examined. Formalin-induced and thermal but not mechanical stimuli increased the "tonic" release of immunoreactive Met-enkephalin from this nuc...

journal_title：Brain research bulletin

authors： Kuraishi Y,Sugimoto M,Hamada T,Kayanoki Y,Takagi H

更新日期：1984-01-01 00:00:00

abstract：:The microdialysis method was utilized to study the effects of N omega-nitro-L-arginine (L-NNA) and N omega-nitro-D-arginine (D-NNA), an inhibitor of nitric oxide (NO) synthesis from L-arginine and its D-enantiomer, on spontaneous and N-methyl-D-aspartate (NMDA)-evoked overflow of striatal extracellular dopamine (DA) i...

journal_title：Brain research bulletin

authors： Ishida Y,Yamamoto R,Mitsuyama Y

更新日期：1994-01-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of activation of metabotropic glutamate receptors (mGluR) on the extracellular concentrations of GABA and acetylcholine in the prefrontal cortex of freely moving rats of different groups of age. Perfusion, through the microdialysis probe, of the agonist of mG...

journal_title：Brain research bulletin

authors： Segovia G,Mora F

更新日期：2005-02-15 00:00:00

abstract：:In a previous study, it was shown that the lateral entorhinal cortex (LEC) in the left hemisphere contains higher concentration of glutamate than in the right hemisphere. The purpose of the present study was to examine potential relationship between this neurochemical asymmetry and behavior. Rats with either left, rig...

journal_title：Brain research bulletin

authors： Myhrer T,Iversen EG

更新日期：1990-08-01 00:00:00

abstract：:We have previously demonstrated that chronic 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) infusion to the substantia nigra (SN) and the locus coeruleus (LC) both produce a long-lasting neurotoxicity on dopamine (DA) and norepinephrine (NE) neurons in these two areas, respectively. In the present study, we furth...

journal_title：Brain research bulletin

authors： Chang FW,Wang SD,Lu KT,Lee EH

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:DTNBP1 gene variation and lower dysbindin-1 protein are associated with schizophrenia. Previous evidence suggests that downregulated dysbindin-1 expression results in lower expression of copper transporters ATP7A (intracellular copper transporter) and SLC31A1 (CTR1; extracellular copper transport...

journal_title：Brain research bulletin

authors： Schoonover KE,McMeekin LJ,Farmer CB,Varghese NE,Queern SL,Lapi SE,Cowell RM,Roberts RC

更新日期：2020-11-01 00:00:00

abstract：:The entopeduncular nucleus (EPN), as the medial part of the globus pallidum, has been considered the efferent structure of the striatum. Based on this, we decided to study its possible somatosensory projections and the electrophysiological relationship with the caudate nucleus (CN). Radial nerve stimulation produced e...

journal_title：Brain research bulletin

authors： Saavedra de Camargo B,Brust-Carmona H,Roig JA

更新日期：1981-03-01 00:00:00

abstract：:Gonadal hormones exert a critical influence over the architecture of specific brain areas affecting the formation of neuronal contacts. Cellular mechanisms mediating gonadal hormone actions on synapses have been studied extensively in the rat arcuate nucleus, a hypothalamic center involved in the feed-back regulation ...

journal_title：Brain research bulletin

authors： Fernandez-Galaz MC,Morschl E,Chowen JA,Torres-Aleman I,Naftolin F,Garcia-Segura LM

更新日期：1997-01-01 00:00:00

abstract：:Evidence concerning the presence or absence of common neuronglia lineages in the postnatal mammalian central nervous system is still a matter of speculation. We address this problem using optic nerve explants, which show an extremely long survival in culture. Morphological, immunocytochemical and immunochemical method...

journal_title：Brain research bulletin

authors： Omlin FX,Riederer BM

更新日期：1992-01-01 00:00:00

abstract：:The topographical distribution of cholinergic cell bodies has been studied in the rat brain and spinal cord by choline acetyltransferase (ChAT)-immunohistochemistry and acetylcholinesterase (AChE)-pharmacohistochemistry using diisopropylfluorophosphate (DFP). The ChAT-containing cells and the cells that stained intens...

journal_title：Brain research bulletin

authors： Satoh K,Armstrong DM,Fibiger HC

更新日期：1983-12-01 00:00:00

abstract：:The effects of ACTH4-10, a peptide fragment of corticotropin, on rat dorsal root ganglia (DRG), spinal cord and sciatic nerve were studied following a crush lesion of the sciatic nerve. The in vitro total protein synthesis rate of DRG L4, L5 and L6, measured one and three days after ipsilateral nerve crush, were not a...

journal_title：Brain research bulletin

authors： Edwards PM,Verhaagen J,Spierings T,Schotman P,Jennekens FG,Gispen WH

更新日期：1985-09-01 00:00:00

abstract：:Several hypotheses have been proposed to explain why some neurological patients fail to recognise objects from unusual views: that it results from difficulty identifying an object's principal axis when it is foreshortened, identifying an object when landmark features are occluded, or an inability to rotate mental imag...

journal_title：Brain research bulletin

authors： Turnbull OH,McCarthy RA

更新日期：1996-01-01 00:00:00

abstract：:Gamma-secretase (GS) is an enzyme complex that cleaves numerous substrates, and it is best known for cleaving amyloid precursor protein (APP) to form amyloid-beta (Aβ) peptides. Aberrant cleavage of APP can lead to Alzheimer's disease, so much research has been done to better understand GS structure and function in ho...

journal_title：Brain research bulletin

authors： Carroll CM,Li YM

更新日期：2016-09-01 00:00:00

abstract：:Expression of the Huntington's disease (HD) mutation in mice (R6/2 line) causes a progressive neurological phenotype that includes deterioration of motor function resembling that seen in HD. The current study sought to determine whether or not chronic treatment of R6/2 mice with lithium chloride would have an effect o...

journal_title：Brain research bulletin

authors： Wood NI,Morton AJ

更新日期：2003-08-30 00:00:00

abstract：:To compare the developmental pattern of the visual tecto- and thalamofugal pathways in the altricial pigeon, we examined the posthatch differentiation of the retinothalamic system. Choleratoxin was injected into the left and right eye to visualize the retinal innervation pattern of the lateral geniculate nucleus of th...

journal_title：Brain research bulletin

authors： Manns M,Freund N,Güntürkün O

更新日期：2008-03-18 00:00:00

abstract：:This study aimed to assess whether changes in the patterns of local field potential (LFP) oscillations of the subthalamic nucleus (STN) underlie to the clinical improvement within 60 s after turning off subthalamic DBS. We studied by spectral analysis the STN LFPs recorded in 13 nuclei from 7 patients with Parkinson's...

journal_title：Brain research bulletin

authors： Foffani G,Ardolino G,Egidi M,Caputo E,Bossi B,Priori A

更新日期：2006-03-31 00:00:00

abstract：:Complex interactions between genetic and environmental factors exert a sustained influence on the pathogenesis of schizophrenia (SCZ). Adolescent social isolation is regarded as a typical paradigm for SCZ. However, the underlying pathological mechanisms are not fully understood. In this study, adolescent Sprague-Dawle...

journal_title：Brain research bulletin

authors： Sun L,Min L,Li M,Shao F,Wang W

更新日期：2018-09-01 00:00:00

abstract：:Neurochemical analysis of norepinephrine and serotonin with high performance liquid chromatography with electrochemical detection (LCEC) in several microdissected central autonomic nuclei of 4 week old and 16 week old spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto rats (WKY), and control normotensive...

journal_title：Brain research bulletin

authors： Felten SY,Weyhenmeyer JA,Felten DL

更新日期：1984-09-01 00:00:00

abstract：:Iontophoretic application of the sigma ligands, 1,3-di-o-tolylguanidine (DTG), dextrallorphan, and (+)-pentazocine reliably inhibited the firing rate of rubral neurons. Dextrallorphan inhibited 87% of the neurons tested, DTG inhibited 76%, and (+)-pentazocine inhibited 50%. These inhibitions were current dependent and...

journal_title：Brain research bulletin

authors： Matsumoto RR,Walker JM

更新日期：1992-09-01 00:00:00

abstract：:Unit activities of thermosensitive (TS) and non-TS neurons in the medial preoptic area (MPO) of the monkey were investigated during a high fixed-ratio (FR 12-30) bar press behavior to seek cool air (CT) in a warm environment. The monkey performed the task when ambient temperature (Ta) was raised (35-43 degrees C) and ...

journal_title：Brain research bulletin

authors： Hori T,Kiyohara T,Oomura Y,Nishino H,Aou S,Fujita I

更新日期：1987-05-01 00:00:00

abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:A modified synaptosomal superfusion apparatus is described which uses less than 10 micrograms of tissue per replicate sample and facilitates the routine separation of 3H-DA, 3H-DOPAC, and 3H-HVA. A flow rate of 1.5 ml/min allows superfusion without the use of reuptake or monoamine oxidase inhibitors. Superfusate sampl...

journal_title：Brain research bulletin

authors： Petrie EC,Lombrozo L,Csernansky JG

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is a gaseous molecule that modulates several physiological processes, including signal transmission in the central nervous system. There is evidence supporting NO as a major neurotransmitter involved in motor and emotion/behavior control. We investigated the distribution and morphology of n...

journal_title：Brain research bulletin

authors： Santos-Lobato BL,Del-Bel E,Pittella JE,Tumas V

更新日期：2016-06-01 00:00:00