Neuronal firing patterns during generalized penicillin epilepsy in the awake cat.

abstract：:Here we have investigated whether differences in levels of dopamine D1-like, D2-like receptors, dopamine D3 receptors, and dopamine transporter could be related to behaviors such as immobility response and locomotion between Wistar rats and Sprague-Dawley rats. The levels of the dopamine receptors and transporter were...

journal_title：Brain research bulletin

authors： Zamudio S,Fregoso T,Miranda A,De La Cruz F,Flores G

更新日期：2005-04-30 00:00:00

abstract：OBJECTIVE:Cerebral ischemic stroke (IS) threatens the daily life of individuals, with high mortality. Emerging studies have deciphered the independent roles of the long non-coding RNA growth-arrest-specific transcript 5 (GAS5), microRNA (miR)-455-5p and phosphatase and tensin homolog (PTEN) in IS, but the understanding...

journal_title：Brain research bulletin

authors： Wu R,Yun Q,Zhang J,Bao J

更新日期：2021-02-01 00:00:00

abstract：:A method for bulk preparation of glomerular particles from subdivisions of the bovine cerebellum is presented. This method represents a modification of that previously reported by Hajos et al. [8], which increases the yield of glomerular protein by five-fold (5.5 mg/g wet wt) without compromising structural integrity ...

journal_title：Brain research bulletin

authors： Terrian DM,Butcher WI,Wu PH,Armstrong DL

更新日期：1985-05-01 00:00:00

abstract：:Most neurodegenerative diseases are characterized by intracellular aggregates of insoluble proteins. As for the majority of these disorders, aetiology and pathogenesis are only poorly understood; current nosological concepts are largely based on these molecular signatures of protein aggregates which also provide valua...

journal_title：Brain research bulletin

authors： Arendt T,Stieler JT,Holzer M

更新日期：2016-09-01 00:00:00

abstract：:The brain serotoninergic (5HTergic) system of epileptic subjects can influence their vulnerability to stress. We studied the putative dependency of 5HT neurotransmission parameters on emotional stress, and the presence, types and severity of seizures using rats with genetic generalized (absence and/or audiogenic) epil...

journal_title：Brain research bulletin

authors： Midzyanovskaya IS,Kuznetsova GD,van Luijtelaar EL,van Rijn CM,Tuomisto L,Macdonald E

更新日期：2006-05-31 00:00:00

abstract：:Our previous results showed that neurochemical destruction of the amygdaloid terminal field of the mesolimbic dopaminergic system caused disturbances in body weight regulation and feeding. In the present experiments, it was studied whether 6-hydroxydopamine (6-OHDA)-induced bilateral lesions of the mesolimbic dopamine...

journal_title：Brain research bulletin

authors： Lénárd L,Karádi Z,Jandó G,Yoshimatsu H,Hajnal A,Sándor P,Oomura Y

更新日期：1991-09-01 00:00:00

abstract：:Evidence exists that nitric oxide (NO) may mediate both protective and pathological responses during brain hypoxia (HP). Reactive oxygen species have also been implicated in the pathophysiological response of the brain tissues to HP. Therefore, this study investigated whether a NO precursor, l-arginine (l-arg), a free...

journal_title：Brain research bulletin

authors： Abdel Baky NA,Zaidi ZF,Fatani AJ,Sayed-Ahmed MM,Yaqub H

更新日期：2010-08-30 00:00:00

abstract：:Cranioplasty is a challenge to neurosurgeons, especially considering protection of intracranial contents. In recent years, material choice for cranioplasty is still controversial, which brings complexity to this seemingly straightforward procedure. PEEK, a tough, rigid, biocompatible material, has been used more recen...

journal_title：Brain research bulletin

authors： Zhang J,Tian W,Chen J,Yu J,Zhang J,Chen J

更新日期：2019-11-01 00:00:00

abstract：:The effects of post-training intra-hippocampal injections of group I mGluR agonists and antagonists, were examined in the contextual fear test, in rats. It was found that (S)-3,5-dihydroxyphenylglycine (DHPG) (a mGluR1-5 agonist) decreased, and (RS)-1-aminoindan-1,5-dicarboxylic acid (AIDA) (a mGluR1 antagonist) incre...

journal_title：Brain research bulletin

authors： Maciejak P,Taracha E,Lehner M,Szyndler J,Bidziński A,Skórzewska A,Wisłowska A,Zienowicz M,Płaźnik A

更新日期：2003-11-15 00:00:00

abstract：:Pretreatment with the 5-HT2 antagonist ketanserin and the 5-HT1A/2 antagonist spiperone did not reduce nicotine-induced hypomotility in mice, nor did MDL 7222, a selective 5-HT3 antagonist. In addition, 8-OH-DPAT and buspirone, 5-HT1A agonists, had no significant effects on nicotine-induced hypomotility. However, 8-OH...

journal_title：Brain research bulletin

authors： Damaj MI,Glennon RA,Martin BR

更新日期：1994-01-01 00:00:00

abstract：:In the present study, cellular tropism and relative transduction efficiency of AAV2/6, AAV2/8 and AAV2/9 vectors have been tested for the cornea using primary cultures of human corneal fibroblasts. The AAV6, AAV8 and AAV9 serotypes having AAV2 ITR plasmid encoding for alkaline phosphatase (AP) gene were generated by t...

journal_title：Brain research bulletin

authors： Sharma A,Ghosh A,Hansen ET,Newman JM,Mohan RR

更新日期：2010-02-15 00:00:00

abstract：:Accumulating evidence points to the amyloid-β (Aβ) peptide as the culprit in the pathogenesis of Alzheimer's disease (AD). β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a protease that is responsible for initiating Aβ production. Although precise mechanisms that trigger Aβ accumulation remain unc...

journal_title：Brain research bulletin

authors： Ohno M

更新日期：2016-09-01 00:00:00

abstract：:The assumption was made that investigatory behaviors (i.e., ano-genital and general body sniffing) of a female conspecific by a mature male rat, has positive hedonic characteristics. Because reduced interest in pleasurable events (i.e., anhedonia) is diagnostically related to depressive behavior, the hypothesis was ad...

journal_title：Brain research bulletin

authors： Paré WP

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Nitric oxide (NO) is a gaseous molecule that modulates several physiological processes, including signal transmission in the central nervous system. There is evidence supporting NO as a major neurotransmitter involved in motor and emotion/behavior control. We investigated the distribution and morphology of n...

journal_title：Brain research bulletin

authors： Santos-Lobato BL,Del-Bel E,Pittella JE,Tumas V

更新日期：2016-06-01 00:00:00

abstract：:Three models of inducing spinal trauma in experimental animals--weight-dropping model, severance-by-knife model, and laceration-type-lesions model--are reviewed critically. Contributions by these models in understanding paraplegia in anatomical and pathological terms are brought out. Important distinctions between sub...

journal_title：Brain research bulletin

authors： Das GD

更新日期：1989-01-01 00:00:00

abstract：:In alpha-chloralose-anesthetized Sprague-Dawley (SD) rats with unilateral nucleus tractus solitarius (NTS) lesions, injection of the alpha(1)-adrenergic receptor agonist phenylephrine into the contralateral NTS dose-dependently increased arterial pressure (AP). Bunazosin (0.1 nmol) or prazosin (0.36 nmol), an alpha(1)...

journal_title：Brain research bulletin

authors： Tsukamoto K,Ito S,Katsunuma N,Hiratsuka M,Masubuchi Y,Kanai T,Kawabe T,Yajima Y,Kanmatsuse K

更新日期：2002-08-15 00:00:00

abstract：:The distribution of calcitonin gene-related peptide (CGRP)-like immunoreactive (LI) nerve cells and terminals (BST) was studied in the rat. Only the fusiform nucleus was found to consistently contain CGRP-LI neurons. The CRGP-LI terminals had a wide distribution in the BST, being most numerous in the oval and the fusi...

journal_title：Brain research bulletin

authors： Ju G

更新日期：1991-11-01 00:00:00

abstract：:A high correlation between alcohol use and smoking has long been suggested by epidemiological data. We examined the potential behavioral interactions between ethanol and nicotine using ethanol-induced motor incoordination as the test response in mice. Effect of pretreatment of various doses of (-)-nicotine, (-)-cotini...

journal_title：Brain research bulletin

authors： Dar MS,Li C,Bowman ER

更新日期：1993-01-01 00:00:00

abstract：:The rostral pons of the cat and rhesus monkey were examined for the presence of labeled cells following injections of horseradish peroxidase (HRP) into the lumbar spinal cord. Labeled cells were found in the ipsilateral dorsolateral pontine tegmentum and in the contralateral ventrolateral pontine reticular formation. ...

journal_title：Brain research bulletin

authors： Hancock MB,Fougerousse CL

更新日期：1976-03-01 00:00:00

abstract：:The ability of homotypic cortical tissue grafts to induce recovery of function after a gustatory neocortex (GN) lesion was studied using the conditioned taste aversion (CTA) paradigm. On acquisition day, 26 GN-lesioned and 8 sham-lesioned rats were presented with a saccharin solution, followed by an injection of the i...

journal_title：Brain research bulletin

authors： Yirmiya R,Zhou FC,Holder MD,Deems DA,Garcia J

更新日期：1988-05-01 00:00:00

abstract：:Postpartum female rats exhibit a suppression of anxiety-related behaviors when compared to diestrous virgin females, pregnant females, and males. This blunted anxiety promotes optimal maternal care and involves elevated GABA neurotransmission, possibly including greater density of GABA(A) and benzodiazepine receptors ...

journal_title：Brain research bulletin

authors： Miller SM,Lonstein JS

更新日期：2011-08-10 00:00:00

abstract：:Acute inflammation activates macrophages or monocytes and subsequently releases several inflammatory cytokines and reactive oxygen and nitrogen species. These proinflammatory cytokines activate astrocytes and trigger neurodegenerative diseases. In this work, we chose to address the mechanistic aspects of alpha-crystal...

journal_title：Brain research bulletin

authors： Masilamoni JG,Vignesh S,Kirubagaran R,Jesudason EP,Jayakumar R

更新日期：2005-10-15 00:00:00

abstract：:Trisomy of the whole or distal part of human chromosome 21 (HSA 21) (Ts21) results in Down Syndrome (DS), which is characterized in part by mental retardation and associated neurological abnormalities. Structural abnormalities observed frequently include reduced brain weight, decreased number and depth of sulci in the...

journal_title：Brain research bulletin

authors： Coyle JT,Oster-Granite ML,Gearhart JD

更新日期：1986-06-01 00:00:00

abstract：:The effects of streptozotocin-induced (STZ) diabetes on the release of gonadotropins was studied in female rats. In the first experiment, rats were ovariectomized and 2 days later were injected with STZ. Three weeks later rats were treated with estrogen and progesterone and blood samples were taken via intraatrial can...

journal_title：Brain research bulletin

authors： Kienast SG,Fadden C,Steger RW

更新日期：1993-01-01 00:00:00

abstract：:Effects of acute exposure (2 hr) to either 1.5% halothane or 0.5% methoxyflurane were investigated in the Sprague Dawley rat. Pituitary (PIT) and central nervous system (CNS) substance P (SP)-like and beta-endorphin (beta-end)-like immunoreactivities were evaluated immediately after anesthetic exposure (2 h), after ri...

journal_title：Brain research bulletin

authors： Karuri AR,Agarwal RK,Engelking LR,Kumar MS

更新日期：1998-03-15 00:00:00

abstract：:The pattern of NADPH-diaphorase expression was studied in the retina and optic tectum of the cichlid fish Tilapia mariae during the first developmental stages. NADPH-diaphorase activity was seen early, at hatching. In the retina a few cell bodies of the retinal inner nuclear layer showed a faint labeling. Scattered la...

journal_title：Brain research bulletin

authors： Villani L,Minelli D,Giuliani A,Quaglia A

更新日期：2001-03-15 00:00:00

abstract：:Metallothioneins (MTs) (I+II) play pivotal roles in metal-related cell homeostasis because of their high affinity for metals forming clusters. The main functional role of MTs is to sequester and/or dispense zinc participating in zinc homeostasis. Consistent with this role, MT gene expression is transcriptionally induc...

journal_title：Brain research bulletin

authors： Mocchegiani E,Giacconi R,Cipriano C,Muzzioli M,Fattoretti P,Bertoni-Freddari C,Isani G,Zambenedetti P,Zatta P

更新日期：2001-05-15 00:00:00

abstract：:The effects of intrathecally (i.t.) administered naloxone or glibenclamide, a blocker of adenosine triphosphate-sensitive potassium (KATP) channels, on the antinociception produced by i.t. apomorphine were observed by an integrated electromyogram measurement of hindlimb flexor reflex in lightly pentobarbital-anestheti...

journal_title：Brain research bulletin

authors： Hu WM,Kang YM,Qiao JT

更新日期：1999-02-01 00:00:00

abstract：:Pax6 is an important transcription factor expressed in several discrete domains of the developing central nervous system. It has been reported that Pax6 is involved in the specification of subtypes of hindbrain motor neurons. Pax6 homozygous mutant (rSey2/rSey2) rats die soon after birth, probably due to impaired resp...

journal_title：Brain research bulletin

authors： Ikeda K,Onimaru H,Inada H,Tien Lin S,Arata S,Osumi N

更新日期：2019-10-01 00:00:00

abstract：:Blood-brain barrier permeability (BBB) to the inhibitory neurotransmitter gamma-amino butyric acid (GABA) was studied in rats following intraperitoneal (i.p) injections of GABA alone and in combination with L-Arginine (L-Arg). Administration of GABA (600 mg/kg body weight [b. wt.]) alone increased brain GABA concentra...

journal_title：Brain research bulletin

authors： Shyamaladevi N,Jayakumar AR,Sujatha R,Paul V,Subramanian EH

更新日期：2002-01-15 00:00:00