Calcitonin gene-related peptide-like immunoreactivity and its relation with neurotensin- and corticotropin-releasing hormone-like immunoreactive neurons in the bed nuclei of the stria terminalis in the rat.

abstract：:The central nervous system (CNS) histaminergic neurons have been shown to regulate feeding behavior and are a target of leptin in the brain. The present study aimed to examine the involvement of the histaminergic system in the leptin-mediated regulation of cardiovascular dynamics. We investigated the cardiovascular re...

journal_title：Brain research bulletin

authors： Rao SP,Dunbar JC

更新日期：2005-01-15 00:00:00

abstract：:Spontaneous locomotion and motor coordination was evaluated in young (5-6 month old) and aged (24-25 month old) rats. Animals were tested for spontaneous locomotor activity in Digiscan Animal Activity Monitors during the nocturnal cycle. Aged animals exhibited a significant hypoactivity compared to their young counter...

journal_title：Brain research bulletin

authors： Emerich DF,McDermott P,Krueger P,Banks M,Zhao J,Marszalkowski J,Frydel B,Winn SR,Sanberg PR

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To establish a link between tryptophan (a precursor for 5-hydroxytryptamine (5-HT) or serotonin, involved in sleep and fatigue) and post-operative fatigue after major surgery. BACKGROUND:There is a link between tryptophan (the precursor for the neurotransmitter 5-hydroxytryptamine), and its competitive bindi...

journal_title：Brain research bulletin

authors： McGuire J,Ross GL,Price H,Mortensen N,Evans J,Castell LM

更新日期：2003-04-15 00:00:00

abstract：:To investigate the direct actions of neurotropin (NSP, a nonproteinaceous extract from inflamed skin of rabbits which is in therapeutic use), intracellular recordings were made from neurons of the ventromedial hypothalamic nucleus (VMH) and lateral hypothalamic area (LHA) in slices of guinea pig brain. In the VMH, NSP...

journal_title：Brain research bulletin

authors： Shimizu N,Duan S,Hori T,Oomura Y

更新日期：1992-12-01 00:00:00

abstract：:Chronic stress, a risk factor for the development of psychiatric disorders, is known to induce alterations in neuronal networks in many brain areas. Previous studies have shown that chronic stress changes the expression of the cannabinoid receptor 1 (CB1) in the brains of adult rats, but neurophysiological consequence...

journal_title：Brain research bulletin

authors： Hu W,Zhang M,Czéh B,Zhang W,Flügge G

更新日期：2011-07-15 00:00:00

abstract：:Among the brain areas studied only pars distalis and pars intermedia are found to contain beta-lipotropin activating enzyme indicating the these may be the exclusive organs for a physiologically significant conversion of beta-lipotropin into beta-endorphin. beta-Endorphin inactivating enzyme is found to be rather unif...

journal_title：Brain research bulletin

authors： Kenessey A,Graf L

更新日期：1977-07-01 00:00:00

abstract：:Postpartum female rats exhibit a suppression of anxiety-related behaviors when compared to diestrous virgin females, pregnant females, and males. This blunted anxiety promotes optimal maternal care and involves elevated GABA neurotransmission, possibly including greater density of GABA(A) and benzodiazepine receptors ...

journal_title：Brain research bulletin

authors： Miller SM,Lonstein JS

更新日期：2011-08-10 00:00:00

abstract：:Crested Ducks (CR) occasionally show intracranial fat bodies. Additionally, behavioral abnormalities such as motor incoordination can be observed. Here, it is shown that a behavioral test helps to identify CR that have a problematical fat body. The ducks were put on their backs, and the time required for them to stand...

journal_title：Brain research bulletin

authors： Cnotka J,Tiemann I,Frahm HD,Rehkämper G

更新日期：2008-06-15 00:00:00

abstract：:The conditions under which amyloid is toxic to primary rat hippocampal neurons were investigated. Synthetic A beta (1-42) peptide elicited neurotoxic activity following "aging" for 7 to 14 days at 37 degrees C in Modified Eagles Media. Neurotoxicity included decreases in neurite length, cell number, and a loss in 3-[4...

journal_title：Brain research bulletin

authors： Manelli AM,Puttfarcken PS

更新日期：1995-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease and is clinically characterised by the death of corticospinal motor neurons (CSMNs), spinal and brainstem MNs and the degeneration of the corticospinal tract. Degeneration of CSMNs and MNs leads inexorably to muscle wastage and weakness, ...

journal_title：Brain research bulletin

authors： Fogarty MJ

更新日期：2018-06-01 00:00:00

abstract：:A cDNA for Drosophila choline acetyltransferase (ChAT) was expressed in E. coli and the recombinant enzyme partially purified. Kinetic analysis yielded the following constants for the recombinant enzyme; KmAcCoA = 29 microM, KmCoA = 25 microM, Kmcholine = 330 microM, and Kmacetylcholine = 2 mM. The recombinant Drosoph...

journal_title：Brain research bulletin

authors： Carbini L,Rodriguez G,Hersh LB

更新日期：1990-01-01 00:00:00

abstract：:Electrophysiological responses to olfactory and gustatory stimuli were recorded in the same neural elements in the parabrachial nuclei (PbN) of rats under Flaxedil. Responses to olfactory stimuli varied in temporal pattern and magnitude from responses to gustatory stimuli. Intravenous infusion of Nembutal while record...

journal_title：Brain research bulletin

authors： Di Lorenzo PM,Garcia J

更新日期：1985-12-01 00:00:00

abstract：:Neuroimaging studies in patients suffering from affective disorders have shown decreased volume and reduced regional cerebral blood flow in multiple areas of the prefrontal cortex, including the medial prefrontal cortex and the orbitofrontal cortex. This aberrant brain activity is among other things attributed to chro...

journal_title：Brain research bulletin

authors： Gerrits M,Westenbroek C,Fokkema DS,Jongsma ME,Den Boer JA,Ter Horst GJ

更新日期：2003-10-15 00:00:00

abstract：:"Responder" Sprague-Dawley (SD) rats that were sensitive to electroacupuncture (EA) in an acute thermal pain test (i.e. tail flick latency [TFL] test) maintained sensitivity to EA in the warm allodynia test after peripheral nerve injury. Similarly, the "non-responder" SD rats that were insensitive to EA in the TFL tes...

journal_title：Brain research bulletin

authors： Kim SK,Moon HJ,Park JH,Lee G,Shin MK,Hong MC,Bae H,Jin YH,Min BI

更新日期：2007-10-19 00:00:00

abstract：:Calcitonin, a peptide hormone expressed in C-cells of the thyreoid gland, as well as capsaicin, isolated from chili, both, modify intracellular signalling in nociceptive neurones. The pathways triggered by the activation of either of these receptors results in a modulation of the intracellular calcium ([Ca(2+)](i)) co...

journal_title：Brain research bulletin

authors： Hagenacker T,Ledwig D,Büsselberg D

更新日期：2011-04-25 00:00:00

abstract：:The distribution of enkephalin-like cell bodies in the thalamus of the rat was studied by means of intratissular injections of colchicine and using an indirect immunoperoxidase technique. The densest clusters of immunoreactive perikarya were observed in the nuclei geniculatum lateralis ventralis, medialis dorsalis, ce...

journal_title：Brain research bulletin

authors： Coveñas R,Alonso JR,Conrath M

更新日期：1989-10-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family, and is widely expressed in the adult mammalian brain. Besides its well known neuroprotective activity after traumatic brain injury the evidences regarding its activity dependent release by the pathophysiology of major depression ar...

journal_title：Brain research bulletin

authors： Yuluğ B,Ozan E,Gönül AS,Kilic E

更新日期：2009-03-30 00:00:00

abstract：:A continuous rhythmic discharge in the subthalamic nucleus (STN), lateral habenular nucleus, and ventral tegmental area (VTA) is associated with tremor in cats lightly anesthetized with barbiturate. The pontine raphe nuclei centralis superior and inferior also show barbiturate dependent slow wave and unitary activity....

journal_title：Brain research bulletin

authors： Sutin J,Tsubokawa T,McBride R

更新日期：1976-01-01 00:00:00

abstract：:Isolated, superfused bullfrog retinas were stimulated in such a manner as to allow examination of the dynamics of the shift in the stimulus-response curve that accompanies light adaptation of cone photoreceptors. Observed phenomena were highly temperature dependent with complex Arrhenius relationships, suggesting that...

journal_title：Brain research bulletin

authors： Haynes LW,Sillman AJ

更新日期：1987-05-01 00:00:00

abstract：:Trans-2, 4-dimethoxystibene (S3) is a synthetic stilbenes. In the present study, S3 was investigated to assess its neuroprotective effect against the toxicity induced by Abeta(25-35) in hypercholesterolemic rats. Rats were fed with hypercholesterolemic chow for six weeks, and then received a single intracerebroventric...

journal_title：Brain research bulletin

authors： Ruan CJ,Li Z,Zhang L,Chen DH,Du GH,Sun L

更新日期：2010-07-30 00:00:00

abstract：:Cellular and molecular mechanisms involved in the generation of seizures and the magnitude of neural cells injury are not fully understood. We evaluated astrocyte and/or neuronal injury in rats in the pentylenetetrazol model of acute seizures by measuring S100B and NSE levels in cerebrospinal fluid. Additionally, we d...

journal_title：Brain research bulletin

authors： Oses JP,Leke R,Portela LV,Lara DR,Schmidt AP,Casali EA,Wofchuk S,Souza DO,Sarkis JJ

更新日期：2004-09-30 00:00:00

abstract：:Theories pertaining to the "why" of motion sickness are in short supply relative to those detailing the "how." Considering the profoundly disturbing and dysfunctional symptoms of motion sickness, it is difficult to conceive of why this condition is so strongly biologically based in humans and most other mammalian and ...

journal_title：Brain research bulletin

authors： Bowins B

更新日期：2010-01-15 00:00:00

abstract：:Although iron is involved in brain function, very little is known about the regulation of its concentrations in the central nervous system. We quantitatively measured the entry and exit rates of iron, transferrin (its major transport protein), and albumin in mice. The blood to brain transport of iron greater than tran...

journal_title：Brain research bulletin

authors： Banks WA,Kastin AJ,Fasold MB,Barrera CM,Augereau G

更新日期：1988-12-01 00:00:00

abstract：:An understanding of the distribution of manganese ions in the brain is of interest in connection with the development of an understanding of the neurotoxicity of this element. Information about the time dependent biodistribution of manganese ions in the brains of intact rats subsequent to single IP injections of MnCl2...

journal_title：Brain research bulletin

authors： London RE,Toney G,Gabel SA,Funk A

更新日期：1989-09-01 00:00:00

abstract：:Epigenetic processes are involved in regulation of cell functions and survival, but their role in responses of neurons and glial cells to oxidative injury is insufficiently explored. Here, we studied the role of DNA methylation and histone deacetylation in reactions of neurons and surrounding glial cells to photodynam...

journal_title：Brain research bulletin

authors： Sharifulina SA,Komandirov MA,Uzdensky AB

更新日期：2014-03-01 00:00:00

abstract：:The regeneration of brain tissue remains one of the greatest unsolved challenges in medicine and by many is considered unfeasible. Indeed, the adult mammalian brain does not regenerate tissue, but there is ongoing endogenous neurogenesis, which is upregulated after injury and contributes to tissue repair. This endogen...

journal_title：Brain research bulletin

authors： Modo M,Badylak SF

更新日期：2019-08-01 00:00:00

abstract：:Deep hypothermic circulatory arrest in cardiothoracic surgery evokes severe brain damages. On the other hand, blood pressure stimuli discontinuation to the brain has been found to induce alterations in neurotransmitter release, including glutamate, in numerous brain regions. Furthermore, it is well established that ex...

journal_title：Brain research bulletin

authors： Kouvelas D,Amaniti E,Pourzitaki C,Kapoukranidou D,Thomareis O,Papazisis G,Vasilakos D

更新日期：2009-04-29 00:00:00

abstract：:Plasma gonadotropins, prolactin and hypothalamic tyrosine hydroxylase (TH) activity were evaluated at 15 and 30 min after third ventricular injection of bombesin at doses of 100 or 1000 ng and secretin at doses of 1000 and 5000 ng in ovariectomized (OVX) unanesthetized rats. Bombesin had no effect on plasma gonadotrop...

journal_title：Brain research bulletin

authors： Babu GN,Vijayan E

更新日期：1983-07-01 00:00:00

abstract：:The nucleus locus coeruleus (LC) has been implicated in the modulation of the spinal sensorimotor function. The aim of the present study was to examine the effect of electrical stimulation of the LC on sensorimotor function in the trigeminal system. The following two cases of sensorimotor behaviors mediated by the tri...

journal_title：Brain research bulletin

authors： Matsutani K,Tsuruoka M,Shinya A,Furuya R,Kawawa T

更新日期：2000-12-01 00:00:00

abstract：:Intelligence depends on the ability of the brain to acquire and apply rules and representations. At the neuronal level these properties have been shown to critically depend on the prefrontal cortex. Here we present, in the context of the Distributed Adaptive Control architecture (DAC), a biologically based model for f...

journal_title：Brain research bulletin

authors： Duff A,Fibla MS,Verschure PF

更新日期：2011-06-30 00:00:00