Intrastriatal implants of fetal mesencephalic cells attenuate the increases in striatal proenkephalin mRNA observed after unilateral 6-hydroxydopamine-induced lesions of the striatum.

abstract：:Although it is well established that increases in tryptophan availability can increase brain serotonin synthesis, the effect of tryptophan loads on serotonin release is not as clear. We have used in vivo microdialysis in order to monitor extracellular serotonin in the lateral hypothalamus to examine this issue. Trypto...

journal_title：Brain research bulletin

authors： Schwartz DH,Hernandez L,Hoebel BG

更新日期：1990-12-01 00:00:00

abstract：:In female rats, stimulation of the uterine cervix during mating induces two daily surges of prolactin. Inhibition of hypothalamic dopamine release and stimulation of oxytocin neurons in the paraventricular nucleus (PVN) are required for prolactin secretion. We aim to better understand how stimulation of the uterine ce...

journal_title：Brain research bulletin

authors： Poletini MO,McKee DT,Szawka RE,Bertram R,Helena CV,Freeman ME

更新日期：2012-09-01 00:00:00

abstract：:The assumption was made that investigatory behaviors (i.e., ano-genital and general body sniffing) of a female conspecific by a mature male rat, has positive hedonic characteristics. Because reduced interest in pleasurable events (i.e., anhedonia) is diagnostically related to depressive behavior, the hypothesis was ad...

journal_title：Brain research bulletin

authors： Paré WP

更新日期：2000-12-01 00:00:00

abstract：:Urethane is often used as a central anaesthetic in neurophysiological studies of drug effects. In this experiment, the effect of morphine on cortical EEG and single units of hippocampus and medial thalamus were compared in urethane-anaesthetized and paralyzed-awake rats. In each case, there was evidence of a morphine-...

journal_title：Brain research bulletin

authors： Linseman MA

更新日期：1980-03-01 00:00:00

abstract：:The susceptibility of the developing brain to hypoxia should depend on the lipid composition of the brain cell membrane; the rate of lipid peroxidation; the presence of antioxidant defenses; and the development and modulation of the excitatory neurotransmitter receptors such as the N-methyl-D-aspartate (NMDA) receptor...

journal_title：Brain research bulletin

authors： Mishra OP,Delivoria-Papadopoulos M

更新日期：1999-02-01 00:00:00

abstract：:Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had...

journal_title：Brain research bulletin

authors： Eisenman JS

更新日期：1983-06-01 00:00:00

abstract：:Unit activities of thermosensitive (TS) and non-TS neurons in the medial preoptic area (MPO) of the monkey were investigated during a high fixed-ratio (FR 12-30) bar press behavior to seek cool air (CT) in a warm environment. The monkey performed the task when ambient temperature (Ta) was raised (35-43 degrees C) and ...

journal_title：Brain research bulletin

authors： Hori T,Kiyohara T,Oomura Y,Nishino H,Aou S,Fujita I

更新日期：1987-05-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a degenerative disease with a progressive loss of motor neurons in the central nervous system (CNS). However, there are unsolved problems with the therapies for this disease. α-Lipoic acid (LA) is a natural, universal antioxidant capable of scavenging hydroxyl radicals as well as...

journal_title：Brain research bulletin

authors： Wang T,Cheng J,Wang S,Wang X,Jiang H,Yang Y,Wang Y,Zhang C,Liang W,Feng H

更新日期：2018-06-01 00:00:00

abstract：:Trans-2, 4-dimethoxystibene (S3) is a synthetic stilbenes. In the present study, S3 was investigated to assess its neuroprotective effect against the toxicity induced by Abeta(25-35) in hypercholesterolemic rats. Rats were fed with hypercholesterolemic chow for six weeks, and then received a single intracerebroventric...

journal_title：Brain research bulletin

authors： Ruan CJ,Li Z,Zhang L,Chen DH,Du GH,Sun L

更新日期：2010-07-30 00:00:00

abstract：:Prostaglandin E2 may not be solely responsible for hyperthermia produced by central administration of sodium arachidonate. To determine its effect, if any, on body temperature prostacyclin sodium salt, another product of prostaglandin endoperoxides, was injected into the third cerebral ventricle of unrestrained, unane...

journal_title：Brain research bulletin

authors： Clark WG,Lipton JM

更新日期：1979-01-01 00:00:00

abstract：:The effect of regucalcin, a Ca(2+)-binding protein, on Ca(2+)-dependent protein kinase activity in the brain cytosol of rats with different ages (5 and 50 weeks old) was investigated. The addition of calmodulin (10 microg/ml) or dioctanoylglycerol (5 microg/ml) in the enzyme reaction mixture caused a significant incre...

journal_title：Brain research bulletin

authors： Hamano T,Hanahisa Y,Yamaguchi M

更新日期：1999-10-01 00:00:00

abstract：:The medial preoptic area is a key structure in the neural control of reproduction. Considerable evidence has accumulated indicating that glutamatergic innervation of the area plays an important role in this control. Sources of the glutamatergic input are unknown. Present investigations were aimed at studying this ques...

journal_title：Brain research bulletin

authors： Kocsis K,Kiss J,Csáki A,Halász B

更新日期：2003-08-30 00:00:00

abstract：:The hypothalamic suprachiasmatic nucleus (SCN) of the ring dove was demonstrated by the presence of labeled retinal processes. Horseradish peroxidase or tritiated proline were injected into the vitreous of the eye and were transported in an anterograde manner to label the SCN. After identifying the retinorecipient are...

journal_title：Brain research bulletin

authors： Cooper ML,Pickard GE,Silver R

更新日期：1983-05-01 00:00:00

abstract：:Expression of the Huntington's disease (HD) mutation in mice (R6/2 line) causes a progressive neurological phenotype that includes deterioration of motor function resembling that seen in HD. The current study sought to determine whether or not chronic treatment of R6/2 mice with lithium chloride would have an effect o...

journal_title：Brain research bulletin

authors： Wood NI,Morton AJ

更新日期：2003-08-30 00:00:00

abstract：:To examine synaptic input and association of terminals containing dopamine and other transmitters to rat striatal nitric oxide synthase-expressing neurons, an electron microscopic study using tyrosine hydroxylase (TH) immunohistochemistry combined with histochemistry for NADPH-diaphorase (NADPHd) was performed. NADPHd...

journal_title：Brain research bulletin

authors： Fujiyama F,Masuko S

更新日期：1996-01-01 00:00:00

abstract：:Epigenetic processes are involved in regulation of cell functions and survival, but their role in responses of neurons and glial cells to oxidative injury is insufficiently explored. Here, we studied the role of DNA methylation and histone deacetylation in reactions of neurons and surrounding glial cells to photodynam...

journal_title：Brain research bulletin

authors： Sharifulina SA,Komandirov MA,Uzdensky AB

更新日期：2014-03-01 00:00:00

abstract：:The neuronal tracer DiI was applied to different brain centers of the rainbow trout in order to study the connections of pretectal nuclei. Our results showed that some pretectal nuclei receive a direct projection from the contralateral retina: the parvocellular superficial pretectal nucleus, the central pretectal nucl...

journal_title：Brain research bulletin

authors： Folgueira M,Anadón R,Yáñez J

更新日期：2008-03-18 00:00:00

abstract：:Polymerase chain reaction assays are a powerful tool for detecting the presence of infectious genomes in the cerebrospinal fluid. Positive results always mean a current or pending infection of the central nervous system. Subacute (>7 days) or chronic infections induce an intrathecal humoral immune response and the app...

journal_title：Brain research bulletin

authors： Sindic CJ,Van Antwerpen MP,Goffette S

更新日期：2003-08-15 00:00:00

abstract：:Although neural occlusion has been suggested to occur between the central and reflex mechanisms increasing arterial pressure, evidence consistent with this phenomenon is lacking. To assess the possibility of neural occlusion we recorded, in chloralose-anesthetized cats, the pressor responses to statically contracting ...

journal_title：Brain research bulletin

authors： Rybicki KJ,Stremel RW,Iwamoto GA,Mitchell JH,Kaufman MP

更新日期：1989-02-01 00:00:00

abstract：:The effect of lithium chloride on the activity of the afferent nerve fibers from the abdominal organs was studied in anesthetized rats. The administration of the lithium chloride solution (0.15 M) over the mesentery increased afferent discharge rate of the splanchnic and vagal gastric nerve. Injection of the same solu...

journal_title：Brain research bulletin

authors： Niijima A,Yamamoto T

更新日期：1994-01-01 00:00:00

abstract：:Concomitant behavioral and dorsal raphe (DR) neuronal activity were recorded following acute and chronic dose response of methylphenidate (MPD) in freely moving rats previously implanted with permanent semi-microelectrodes using telemetric (wireless) technology. On experimental day (ED) 1, the neuronal and locomotor a...

journal_title：Brain research bulletin

authors： Tang B,Dafny N

更新日期：2013-09-01 00:00:00

abstract：:Calcitonin, a peptide hormone expressed in C-cells of the thyreoid gland, as well as capsaicin, isolated from chili, both, modify intracellular signalling in nociceptive neurones. The pathways triggered by the activation of either of these receptors results in a modulation of the intracellular calcium ([Ca(2+)](i)) co...

journal_title：Brain research bulletin

authors： Hagenacker T,Ledwig D,Büsselberg D

更新日期：2011-04-25 00:00:00

abstract：:Diabetic encephalopathy has recently been recognized late complication of diabetes resulting in progressive cognitive deficits. Emerging evidence has indicated that endoplasmic reticulum (ER) stress-mediated apoptosis is involved in the pathogenesis of diabetic eye and kidney as well as non-diabetic neurodegeneration....

journal_title：Brain research bulletin

authors： Zhao Y,Yan Y,Zhao Z,Li S,Yin J

更新日期：2015-02-01 00:00:00

abstract：:This study was performed to elucidate the mechanism by which adenosine triphosphate (ATP) encapsulated into liposomes was able to protect against experimental brain ischemia in the rat. After intracarotidal administration of liposomally entrapped ATP, the ATP blood level increased dramatically whereas no change was ob...

journal_title：Brain research bulletin

authors： Chapat S,Frey V,Claperon N,Bouchaud C,Puisieux F,Couvreur P,Rossignol P,Delattre J

更新日期：1991-03-01 00:00:00

abstract：:The aim of this study was to investigate whether primary vestibular afferent fibers establish direct connections with the motor and sensory trigeminal system in the brainstem of the frog. The experiments were carried out on Rana esculenta. In anaesthetized animals the trigeminal and vestibular nerves were prepared, an...

journal_title：Brain research bulletin

authors： Matesz C,Kovalecz G,Veress G,Deák A,Rácz E,Bácskai T

更新日期：2008-03-18 00:00:00

abstract：:Long chain fatty acids (FA) and 2-monoacylglycerols (MG) are produced by lipoprotein lipase (LPL) from plasma triacylglycerols (TG) in capillaries of adipose tissue and transported to adipocytes for TG synthesis. It is widely proposed FA may be transported in cells by FA-binding protein. Mode of transport of MG has re...

journal_title：Brain research bulletin

authors： Scow RO,Blanchette-Mackie EJ

更新日期：1991-09-01 00:00:00

abstract：:Body weight changes and food and water intakes were studied in CFY male and female rats after kainic acid (KA)-induced destruction of the lateral hypothalamic area (LH) or the ventromedial hypothalamic nucleus (VMH). To minimize the extent of damages, KA was iontophoretically applied by means of glass micropipettes. K...

journal_title：Brain research bulletin

authors： Lénárd L,Sándor P,Hajnal A,Jandó G,Karádi Z,Kai Y

更新日期：1991-01-01 00:00:00

abstract：:Parkinson's disease (PD) is mostly known as a dopamine deficiency syndrome due the structural and functional changes in striatal projection neurons. However, studies have considered this pathology as a multi-systemic disease in which the neurodegenerative process extends beyond the dopaminergic system. Therefore, the ...

journal_title：Brain research bulletin

authors： Leal PC,Bispo JMM,Lins LCRF,Souza MF,Gois AM,Moore C,Marchioro M,Ribeiro AM,Silva RH,Meshul CK,Santos JR

更新日期：2019-03-01 00:00:00

abstract：:Bilateral inferior olive lesions, produced by systemic administration of the neurotoxin 3-acetylpyridine (3AP) produce a proconvulsant state specific for strychnine-induced seizures and myoclonus. We have proposed that these phenomena are mediated through increased excitation of cerebellar Purkinje cells, through acti...

journal_title：Brain research bulletin

authors： Anderson MC,Chung EY,Van Woert MH

更新日期：1990-10-01 00:00:00

abstract：:The effects of chronic administration of delta 9-tetrahydrocannabinol (delta 9-THC) on the plasma and brain catecholamine (CA) levels were measured using high performance liquid chromatography-electrochemical detection (LC-EC) system. Intact male rats were injected daily with vehicle (50 microliter oil) or with delta ...

journal_title：Brain research bulletin

authors： Patel V,Borysenko M,Kumar MS

更新日期：1985-01-01 00:00:00