Increased expression of HERPUD1 involves in neuronal apoptosis after intracerebral hemorrhage.

abstract：:A microdialysis probe, implanted in the posterior hypothalamus (PH) was used to examine changes of extracellular norepinephrine (NE) in freely moving rats from which mean arterial pressure (mAP) and heart rate (HR) were continuously monitored. Artificial cerebrospinal fluid (aCSF) was pumped through the probe and 10-m...

journal_title：Brain research bulletin

authors： Nakata T,Berard W,Kogosov E,Alexander N

更新日期：1990-10-01 00:00:00

abstract：:Interleukin-1beta (IL-1beta), a cytokine with pronounced central effects such as fever, anorexia, analgesia, etc., is also known to activate the hypothalamo-pituitary-adrenal (HPA) axis. Corticotropin releasing hormone (CRH) neurons located in the hypothalamus are important for HPA activation. The cell bodies of CRH n...

journal_title：Brain research bulletin

authors： MohanKumar SM,MohanKumar PS

更新日期：2005-05-15 00:00:00

abstract：:The large neurons in the rat neostriatum consist of at least two morphologically distinct types in Golgi preparations: Type I large cells had smooth somata whereas type II large cells had somatic spines. In the present study, the ultrastructural morphology of the Golgi-stained large neostriatal neurons in the rat was ...

journal_title：Brain research bulletin

authors： Chang HT,Kitai ST

更新日期：1982-06-01 00:00:00

abstract：:Although increasing evidence indicates that psychiatric symptoms are crucial characteristic of the early stage of Parkinson's disease (PD) and precede motor impairments, the neuronal firing activity of the basolateral nucleus of the amygdala (BLA) in the psychiatric symptom of PD and the involved mechanism are still u...

journal_title：Brain research bulletin

authors： Chen L,Liu J,Zhang QJ,Feng JJ,Gui ZH,Ali U,Wang Y,Fan LL,Hou C,Wang T

更新日期：2011-07-15 00:00:00

abstract：:Rats were unilaterally deprived of odor stimulation by surgically sealing one naris 1, 30 or 60 days after birth. Thirty days later the laminar volumes of the olfactory bulb ipsilateral to the occluded naris were compared with those ipsilateral to the normal side. Deprivation from days 1-30 resulted in approximately 2...

journal_title：Brain research bulletin

authors： Brunjes PC,Borror MJ

更新日期：1983-11-01 00:00:00

abstract：:Effects of hypothalamic stimulation and lesion on hepatic autonomic nerve activity were investigated in anesthetized rats. Stimulation of the lateral hypothalamic area increased activity of the hepatic vagal nerve and decreased activity of the splanchnic nerve. Lesion of this area produced a rapid and strong reduction...

journal_title：Brain research bulletin

authors： Yoshimatsu H,Niijima A,Oomura Y,Katafuchi T

更新日期：1988-08-01 00:00:00

abstract：:Iontophoretic application of the sigma ligands, 1,3-di-o-tolylguanidine (DTG), dextrallorphan, and (+)-pentazocine reliably inhibited the firing rate of rubral neurons. Dextrallorphan inhibited 87% of the neurons tested, DTG inhibited 76%, and (+)-pentazocine inhibited 50%. These inhibitions were current dependent and...

journal_title：Brain research bulletin

authors： Matsumoto RR,Walker JM

更新日期：1992-09-01 00:00:00

abstract：OBJECTIVE:Parkinson's disease (PD) is a frequent degenerative disease of the nervous system with undefined pathogenesis. This study explored the protective effect of microRNA (miR)-218-5p on dopaminergic neuron injury in substantia nigra (SN) of rats with PD through the regulation of LIM and SH3 domain protein 1 (LASP1...

journal_title：Brain research bulletin

authors： Ma X,Zhang H,Yin H,Geng S,Liu Y,Liu C,Zhao J,Liu Y,Wang X,Wang Y

更新日期：2021-01-01 00:00:00

abstract：:The effects of intraseptally microinjected muscarinic (atropine sulfate, pirenzepine and gallamine) and nicotinic (hexamethonium) antagonists on spontaneous, sensory and electrically-induced hippocampal (HPC) theta EEG activity were investigated in the freely behaving cat. Administration of hexamethonium failed to eli...

journal_title：Brain research bulletin

authors： Gołebiewski H,Eckersdorf B,Konopacki J

更新日期：2002-07-01 00:00:00

abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:A method for constructing a simple spike counter from a conventional calculator by taking advantage of the "adding display to memory" function [(M+) key] is described. The modification involves connecting the (M+) key to a dissecting pin and to a metallic notebook binder which is taped on to a transparent plastic shee...

journal_title：Brain research bulletin

authors： Chan A,Dudley CA,Moss RL

更新日期：1983-12-01 00:00:00

abstract：:In this study we investigated the ability of the dentate gyrus to independently generate cholinergically induced theta rhythm in vitro. Two different experiments were performed. In Experiment I, new laminar profiles of theta phase, amplitude, and current sources and sinks were constructed. In this experiment a gradual...

journal_title：Brain research bulletin

authors： Kowalczyk T,Gołebiewski H,Konopacki J

更新日期：2009-09-28 00:00:00

abstract：:Serotonergic modulation of acetylcholine (ACh) release after neuron-specific increase of the expression of 5-HT(1B) receptors by gene transfer was studied in vitro and in vivo. The increased expression of the 5-HT(1B) receptor in vitro was induced by treating rat primary fetal septal cell cultures for 3 days with a vi...

journal_title：Brain research bulletin

authors： Riegert C,Rothmaier AK,Leemhuis J,Sexton TJ,Neumaier JF,Cassel JC,Jackisch R

更新日期：2008-07-01 00:00:00

abstract：:The olfactory bulbectomized (OBX) rat model of depression has been widely used in studies on the behavioral and neurochemical aspects of human depression. The objective of the present investigation was to assess open field (OF) activity and the brain regional 5-HT(1A) receptor densities of the sham operated (SHX) and ...

journal_title：Brain research bulletin

authors： Sato H,Skelin I,Debonnel G,Diksic M

更新日期：2008-03-28 00:00:00

abstract：:Stroke is one of the leading causes of mortality and morbidity worldwide. Due to its poor prognosis, there is a major negative impact on the patients and their family's life quality. However, despite the severity of this pathology tissue plasminogen activator (tPA) is the only FDA approved treatment for ischemic strok...

journal_title：Brain research bulletin

authors： Bruch GE,Fernandes LF,Bassi BLT,Alves MTR,Pereira IO,Frézard F,Massensini AR

更新日期：2019-10-01 00:00:00

abstract：:The Lurcher (Lc/+) mutant mouse is characterized by a considerable atrophy of the cerebellum due to a massive loss of cerebellar Purkinje and granule cells, as well as of neurons from the inferior olivary nucleus. In this study the effects of a therapeutic combination of amantadine, thiamine and L-tryptophan on the se...

journal_title：Brain research bulletin

authors： Le Marec N,Hébert C,Botez MI,Botez-Marquard T,Marchand L,Reader TA

更新日期：1999-01-15 00:00:00

abstract：:The possible existence of two separate RSA generators in the dorsal hippocampus raises questions as to the degree of coupling or independence of both. In order to answer these questions bipolar EEG recording were made in the CA1 and dentate gyrus of freely moving rats during conditions of RSA generation by different m...

journal_title：Brain research bulletin

authors： Krug M,Brödemann R,Ott T

更新日期：1981-01-01 00:00:00

abstract：:The effects of delta-9-tetrahydrocannabinol (delta-9-THC) on monosynaptic population responses in hippocampal CA1 pyramidal cells were examined in acute rats for several doses and at several post injection time periods. Delta-9-THC enhanced paired pulse inhibition in a dose-dependent manner; however biphasic dose effe...

journal_title：Brain research bulletin

authors： Weisz DJ,Gunnell DL,Teyler TJ,Vardaris RM

更新日期：1982-02-01 00:00:00

abstract：:The aim of this study was to investigate whether the histamine H1-receptor blocker, chlorpheniramine (CPA), has a reinforcing effect in goldfish. We used a place-preference procedure in an aquarium with two chambers colored black and white. On day 1, the animals were placed in the test chamber for 10 min for habituati...

journal_title：Brain research bulletin

authors： Mattioli R,Nelson CA,Huston JP,Spieler RE

更新日期：1998-01-01 00:00:00

abstract：:An animal with an unimpaired "reference" memory can distinguish between alternatives that belong to a rewarded set and those that are unrewarded. An animal with an unimpaired "working" memory can distinguish between alternatives where it has been rewarded (e.g., food has been eaten and not replaced) and those where it...

journal_title：Brain research bulletin

authors： Oades RD

更新日期：1981-08-01 00:00:00

abstract：:The effects of chemically and electrically-induced convulsions on the binding of [3H]Ro 5-4864 to peripheral benzodiazepine receptors (PBR) was studied in both peripheral tissues and the central nervous system (CNS). Acute, maximal electroshock (MES) increased the density of PBR in mouse cerebral cortex as evidenced b...

journal_title：Brain research bulletin

authors： Basile AS,Weissman BA,Skolnick P

更新日期：1987-07-01 00:00:00

abstract：:Cranioplasty is a challenge to neurosurgeons, especially considering protection of intracranial contents. In recent years, material choice for cranioplasty is still controversial, which brings complexity to this seemingly straightforward procedure. PEEK, a tough, rigid, biocompatible material, has been used more recen...

journal_title：Brain research bulletin

authors： Zhang J,Tian W,Chen J,Yu J,Zhang J,Chen J

更新日期：2019-11-01 00:00:00

abstract：:Mice selected for differences in nest-building behavior differ in the number of arginine-vasopressin (AVP)-immunoreactive neurons in the suprachiasmatic nuclei (SCN). Although previous efforts to link AVP-immunoreactive neurons in the SCN to clock function have failed, we show that differences in several circadian par...

journal_title：Brain research bulletin

authors： Bult A,Hiestand L,Van der Zee EA,Lynch CB

更新日期：1993-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a major public-health problem for which mild TBI (MTBI) makes up majority of the cases. MTBI is a poorly-understood health problem and can persist for years manifesting into neurological and non-neurological problems that can affect functional outcome. Presently, diagnosis of MTBI is ba...

journal_title：Brain research bulletin

authors： Kan EM,Ling EA,Lu J

更新日期：2012-03-10 00:00:00

abstract：:A microdrive and microelectrode costing about $2.67 is described. The assembly is lightweight, compact, and versatile and is ideal for chronic single-unit recording from behaving rats. It is easy to assemble and operate and has been used successfully by undergraduates in the teaching and research laboratory. ...

journal_title：Brain research bulletin

authors： Goldberg E,Minerbo G,Smock T

更新日期：1993-01-01 00:00:00

abstract：:The effect of environmental odors emanating from large-scale hog operations on the mood of nearby residents was determined using the POMS (Profile of Mood States). The scores for six POMS factors and the TMD (total mood disturbance score) for 44 experimental subjects were compared to those of 44 control subjects who w...

journal_title：Brain research bulletin

authors： Schiffman SS,Miller EA,Suggs MS,Graham BG

更新日期：1995-01-01 00:00:00

abstract：:The use of neurons induced from stem cells has been introduced as an effective strategy for promoting peripheral nerve regeneration (PNR). The evolution and role of native denervated Schwann cells (SCs) were often ignored when exploring the mechanisms underlying neural transplantation therapy for PNR. The aim of this ...

journal_title：Brain research bulletin

authors： Zheng Y,Huang C,Liu F,Lin H,Niu Y,Yang X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Reports from both this laboratory and others indicate that prenatal exposure of rats to cocaine can produce alterations in development, activity and responses to environmental stimuli. In order to determine a biochemical basis for these effects, radioligand receptor-binding assays for different monoaminergic receptors...

journal_title：Brain research bulletin

authors： Henderson MG,McConnaughey MM,McMillen BA

更新日期：1991-06-01 00:00:00

abstract：:Neonatal post-hemorrhagic hydrocephalus is associated with cognitive decline and a serious deterioration in the patient's quality of life. The underlying impairments to neurons are not well understood. Here, we used the method described by Cherian et al. to construct a model of hydrocephalus after intra-ventricular he...

journal_title：Brain research bulletin

authors： Chen X,Huang X,Li B,Zhao Z,Jiang L,Huang C,Lu Y

更新日期：2010-08-30 00:00:00

abstract：:Calcium/calmodulin-dependent protein-kinase II (CaMKII) is a ubiquitous intracellular enzyme, which is implicated in learning and memory mechanisms in the central nervous system, however its contribution to peripheral cholinergic neurotransmission is not well characterized. This study evaluated the impact of CaMKII on...

journal_title：Brain research bulletin

authors： Mukhamedyarov MA,Kochunova JO,Yusupova ER,Haidarov BA,Zefirov AL,Palotás A

更新日期：2010-04-05 00:00:00