Effects of oxytocin and vasopressin on thoracic sympathetic preganglionic neurones in the cat.

Abstract:

:When applied by iontophoresis onto single sympathetic preganglionic neurones in the intermediolateral nucleus of segments T1-T3 in the cat, oxytocin and vasopressin each had an excitatory effect. This effect consisted of a prolonged (30-300 sec) after-discharge following termination of application. These results indicate that oxytocin and vasopressin each exert excitatory effects on sympathetic preganglionic neurones and support the possibility that they may be chemical mediators of synaptic transmission in the intermediolateral nucleus, perhaps in cardioacceleratory and/or pressor pathways descending from the paraventricular nucleus of the hypothalamus.

journal_name

Brain Res Bull

journal_title

Brain research bulletin

authors

Backman SB,Henry JL

doi

10.1016/0361-9230(84)90201-6

subject

Has Abstract

pub_date

1984-11-01 00:00:00

pages

679-84

issue

5

eissn

0361-9230

issn

1873-2747

pii

0361-9230(84)90201-6

journal_volume

13

pub_type

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